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TSAPSVLEIRALPGTDTYRNLLAQVAEGARDRDLDDENPFDQVRLLKEAGFGRLRIPTELGGAGLSVRQL FSAIIDVAQADPIVAHIFRTHFWFVEERLRTLADPVSAAWLTKVNEGNLFANAFSEKGSLAVGSLVFNTR LLPVGDAYRLNGEKFYSTGTLFADYLTVTATTDRDSVASVIVPGDRDGVRLVDDWDGFGQRRTGTGTTIF SQVDVAADEILSETPYDAAPVPTTQYASLQLYILAIVAGVLRAVVDDGEALLRSRQRNFSHALTERPVDD PLLQRTLGELSATAFAAEATVLAAADAIEAATATLRDGVPDAQLAQEAQVAVAKAKVHIDAVALDAATKL LDLGGASAASRTRNLDRHWRNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1422c | - | - | 100% (405) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4123 | - | 7e-31 | 28.83% (385) | monooxygenase |
| M. abscessus ATCC 19977 | MAB_0075 | - | 1e-11 | 23.37% (398) | putative hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 2e-11 | 23.83% (386) | hypothetical protein Mb3121c |
| M. gilvum PYR-GCK | Mflv_4943 | - | 1e-11 | 23.56% (399) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3094c | - | 2e-11 | 23.83% (386) | hypothetical protein Rv3094c |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 8e-09 | 22.49% (378) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_3433 | - | 9e-12 | 26.26% (377) | oxidoreductase |
| M. avium 104 | MAV_3422 | - | 2e-79 | 41.22% (393) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5001 | - | 1e-167 | 73.12% (398) | pesticide degrading monooxygenase |
| M. thermoresistible (build 8) | TH_3393 | - | 3e-53 | 37.34% (391) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. ulcerans Agy99 | MUL_2707 | - | 1e-10 | 24.93% (377) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 2e-39 | 32.48% (391) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1422c|M.abscessus_ATCC_199 ------MTSAPSVLEIRALPGTDTYRNLLAQVAEGARDR--DLDDENPFD
MSMEG_5001|M.smegmatis_MC2_155 ------MTTVEN--AKRIIPGSPQWSALLAKIAAGARDR--DLGDENPFD
MAV_3422|M.avium_104 ------MPVAFH--RQDTPAGAAAVQPVLAEIAADYRLRLADGGTEPPLR
TH_3393|M.thermoresistible__bu -----VTEPLTMARIVDTAEALAVAARLSGSFAAEASTR--DAERLLPYE
Mvan_3173|M.vanbaalenii_PYR-1 -MATDITDRIPDTLLRTPADALAAAEEVAEAIAAGSAER--ERAGAVLTP
Mflv_4943|M.gilvum_PYR-GCK MP-------VDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
Mb3121c|M.bovis_AF2122/97 ---------------MNQSETEIEILAEKIARWARARSAEIERDRRLPDE
Rv3094c|M.tuberculosis_H37Rv ---------------MNQSETEIEILAEKIARWARARSAEIERDRRLPDE
MMAR_3433|M.marinum_M ---------------------MTAGITDTFVHSLAQRAHEAEKLRRLPAA
MUL_2707|M.ulcerans_Agy99 -----MPSPTLDCHTERYGGLMTAGITDTFVHSLAQRAHEAEKLRRLPAA
:
MAB_1422c|M.abscessus_ATCC_199 QVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAHIFRTH
MSMEG_5001|M.smegmatis_MC2_155 EVNALKRAGFGTLRLPESLGGAGFTVPQLFSAVIDVAQADPIVAHIFRTH
MAV_3422|M.avium_104 GLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPDLAHILRIH
TH_3393|M.thermoresistible__bu QVCELKRSGLLTLSVPAEHGGLDVPATVLAEVFRLLAHGDPSVAQIPHSH
Mvan_3173|M.vanbaalenii_PYR-1 QLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVGQLLLSH
Mflv_4943|M.gilvum_PYR-GCK VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mb3121c|M.bovis_AF2122/97 LVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGWCVSIA
Rv3094c|M.tuberculosis_H37Rv LVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGWCVSIA
MMAR_3433|M.marinum_M TVTELTASGFPDLLKPARYGGQQAEFSAIFDPVRRMAHGCASTAWTAAFY
MUL_2707|M.ulcerans_Agy99 TVTELTASGFPDLLKPARYGGQQAEFSAIFDPVRRMAHGCASTAWPAAFY
. : : . .. :* .
MAB_1422c|M.abscessus_ATCC_199 FWFVEERLRTLADPVSAAWLTKVNEGNLFANAFSEKGSLAVGSLVFNTRL
MSMEG_5001|M.smegmatis_MC2_155 FWFTEERLRTSSDPVSQRWLREIADGKIFGNAFSEKGSLAVGSLVFNTRL
MAV_3422|M.avium_104 YALVEELQVTPRRPGSDRWIAVVAEGGLIGGANAEQSQKSVGGNHRDTRL
TH_3393|M.thermoresistible__bu FTFLEVLRLQGTERQRGFFYGLVLEGALFANAQSERG-PHPIDVDTTVLL
Mvan_3173|M.vanbaalenii_PYR-1 FVVAQAISGLGHTQPAPRIYADLLAGAQLGNASAERGTAHALDRRTTVTR
Mflv_4943|M.gilvum_PYR-GCK SLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCRA
MLBr_00737|M.leprae_Br4923 KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
Mb3121c|M.bovis_AF2122/97 ITSALLVAYLPARSREEMFGGGR---GVAAGVWAPRGTARSVD-------
Rv3094c|M.tuberculosis_H37Rv ITSALLVAYLPARSREEMFGGGR---GVAAGVWAPRGTARSVD-------
MMAR_3433|M.marinum_M ALHNWMLALFDERAQSEGFTTTP---FLAPAPLAPTGRGLPAD-------
MUL_2707|M.ulcerans_Agy99 ALHNWMLALFDERAQSEGFTTTP---FLAPAPLAPTGRGLPAD-------
MAB_1422c|M.abscessus_ATCC_199 LP---VGDAYRLNGEKFYSTGTLFADYLTVTATTDRD---------SVAS
MSMEG_5001|M.smegmatis_MC2_155 LPDPADPGALRLNGEKFYSTGTLFADYLTVTATTDHD---------SVAN
MAV_3422|M.avium_104 VT---TPDGLRLRGRKFYSTGAQFSDYLRITAQDDDG---------APTA
TH_3393|M.thermoresistible__bu RRG---AGDYLLTGRKFYSTGALFADWIVVRASVPADAADAPTAATPKAV
Mvan_3173|M.vanbaalenii_PYR-1 RD-----GHWVLNGTKYYATGTLGATWIAVAARIEGRENGD------TAT
Mflv_4943|M.gilvum_PYR-GCK TAV---DGGYRITGSKAWITHGGIADFYNLFARTG--EGSQG-----ISC
MLBr_00737|M.leprae_Br4923 KAD---GDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANG-----ISA
Mb3121c|M.bovis_AF2122/97 -------GGVVVSGRWPFCSGINHADIMFAG--CFVDDR--------QVP
Rv3094c|M.tuberculosis_H37Rv -------GGVVVSGRWPFCSGINHADIMFAG--CFVDDR--------QVP
MMAR_3433|M.marinum_M -------GGVRLSGRWSWATGVMDGNWIIVGTLCGSDDA--------IYP
MUL_2707|M.ulcerans_Agy99 -------GGVRLSGRWSWATGVMDGNWIIVGTLCGSDDA--------IYP
. : * : : .
MAB_1422c|M.abscessus_ATCC_199 VIVPGDRDGVRL-VDDWDGFGQRRTGTGTTIFSQVDVAADEIL-------
MSMEG_5001|M.smegmatis_MC2_155 VVIPADREGVRL-VDDWDGFGQRRTGTGTTVLTDVAVSPEEVL-------
MAV_3422|M.avium_104 VVIPVDRAGVEH-LDDWDGIGQRQTGSGTTVFNDVAVADDEVF-------
TH_3393|M.thermoresistible__bu AFVPRHAPGLTV-IDDWDGMGQRTTASGSVTLDEVRVPADHVV-------
Mvan_3173|M.vanbaalenii_PYR-1 AFVRPDQEGVTLDLESWSAFGQRGTASGEVRLNNVVVDDDLLID------
Mflv_4943|M.gilvum_PYR-GCK FLVPRDTEGLTFGKPEEK-MGLHAVPTTAAHYDDANLDSDRRIG------
MLBr_00737|M.leprae_Br4923 FIVHKDDEGFSIGPKEKK-LGIKGSPTTELYFDKCRIPGDRIIG------
Mb3121c|M.bovis_AF2122/97 SVVALNKDELQV-LDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDG--
Rv3094c|M.tuberculosis_H37Rv SVVALNKDELQV-LDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDG--
MMAR_3433|M.marinum_M ALALLPANDIRI-IDVWHTDGMRATGSNDVVIEDVFVPTYRLIKVTDIYA
MUL_2707|M.ulcerans_Agy99 ALALLPANDIRI-IDVWHTDGMRATGSNDVVIEDVFVPTYRLIKVTDIYA
. . * : : . : .
MAB_1422c|M.abscessus_ATCC_199 ----SETPYDAAPVPTTQYASLQLYILAIVAGVLRAVVDDGEALLRSRQR
MSMEG_5001|M.smegmatis_MC2_155 ----TDSPYDADPVPTVQYASLQLFIHAVVAGILANVVDDGVALLRSRER
MAV_3422|M.avium_104 ----PLG--STIGVNRARGALVQLYLHAVAAGILRSLTEDAAALVRGRRR
TH_3393|M.thermoresistible__bu ------PFTPIFRRPTVYGARAQLWHAALDVGIATAALEEG-VRLAARAR
Mvan_3173|M.vanbaalenii_PYR-1 ---EGPPPDPITADPSVLGAFDQALHAAIDIGIARAALEDGAVFVRTRSR
Mflv_4943|M.gilvum_PYR-GCK ------TEGQGLQIAFSALDSGRLGIAAVAVGLAQAALDEAVAYSQERTT
MLBr_00737|M.leprae_Br4923 ------EPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
Mb3121c|M.bovis_AF2122/97 ------PIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKG
Rv3094c|M.tuberculosis_H37Rv ------PIVDRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKG
MMAR_3433|M.marinum_M GTTPGSKVHEAPAYRWPLVPALALVAAMPALGAAEHVADVFTARLGERIL
MUL_2707|M.ulcerans_Agy99 GTTPGSKVHEAPAYRWPLVPALALVAAMPALGAAEHVADVFPARLGERIL
* : :
MAB_1422c|M.abscessus_ATCC_199 N---FSHALTERPVDDPLLQRTLGELSATAFAAEATVLAAADAIEAATAT
MSMEG_5001|M.smegmatis_MC2_155 N---FSHAVAERPTDDPLLQRQLGVLASTAYVARAAVLDAAAAIGAATDS
MAV_3422|M.avium_104 T---YTFASADTPTADPQLLQIVGEIDAVAYTAHALVRNAAAELAPALQA
TH_3393|M.thermoresistible__bu P---HFESGAPVATDDPTLIQSAGEVAVTVRAAQALLGEAARAVDAATAD
Mvan_3173|M.vanbaalenii_PYR-1 PWKEALDAGIERADQEPHVVRRFGELTARLYALEALLARGTALIDEAYAA
Mflv_4943|M.gilvum_PYR-GCK FG--------RKIIDHQGLAFLLADMAAAVDSARATYLDAARRRDAGLP-
MLBr_00737|M.leprae_Br4923 FG--------ESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD
Mb3121c|M.bovis_AF2122/97 LG------STRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHD
Rv3094c|M.tuberculosis_H37Rv LG------STRTLAERSATQAAAATAESALGAARALFYEVIEAAWQVSHD
MMAR_3433|M.marinum_M AY------EGAKQQDKPAAQVRVGEARVRLRALHGLLADTVGRIEDILAT
MUL_2707|M.ulcerans_Agy99 AY------EGAKQQDKPAAQVRVGEARVRLRALHGLLADTVGRIEDILAT
. .
MAB_1422c|M.abscessus_ATCC_199 LRDGVPDAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASRTRN
MSMEG_5001|M.smegmatis_MC2_155 AKDGVPDADLAAEAQLKVAKVKVHLDDIAPEAATRLLELGGASAASRQRG
MAV_3422|M.avium_104 ARDTGIDPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQASAL
TH_3393|M.thermoresistible__bu -----LTEDTAAAASIAVATAKVAAERAALRASTALFELGGTRSATVSAN
Mvan_3173|M.vanbaalenii_PYR-1 P---EVTRDAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSGTDGAVN
Mflv_4943|M.gilvum_PYR-GCK -------------YSRHASVAKLVATDAAMKVTTDAVQVLGGAGYTRDYR
MLBr_00737|M.leprae_Br4923 -------------LGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFP
Mb3121c|M.bovis_AF2122/97 A------EAVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAP
Rv3094c|M.tuberculosis_H37Rv A------EAVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAP
MMAR_3433|M.marinum_M G------DRVPRPVRADARLAAAHIVHESRAVIGELLEASGASAHFLNNP
MUL_2707|M.ulcerans_Agy99 G------DRVARPIRADARLAAAHIVHESRAVIGELLEASGASAHFLYNP
: : * .
MAB_1422c|M.abscessus_ATCC_199 LDRHWRNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF-
MSMEG_5001|M.smegmatis_MC2_155 LDRHWRNIRTITLHNPVAYKARVIGQNLLHGTPVPANAYF-
MAV_3422|M.avium_104 LDRHWRNLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF-
TH_3393|M.thermoresistible__bu LSRFWRDARTHTLHDPTRWKLHHIGRYLLSGTRPPRHGQL-
Mvan_3173|M.vanbaalenii_PYR-1 LDRHWRNVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL
Mflv_4943|M.gilvum_PYR-GCK VERYMREAKITQIFEGTNQIQRLVISRHLTRG---------
MLBr_00737|M.leprae_Br4923 VERFMRDAKITQIYEGTNQIQRVVMSRALLR----------
Mb3121c|M.bovis_AF2122/97 LQRRFRDAFTATAHFQVN-EASRELPGRVLLDQPADVSML-
Rv3094c|M.tuberculosis_H37Rv LQRRFRDAFTATAHFQVN-EASRELPGRVLLDQPADVSML-
MMAR_3433|M.marinum_M LQRAKRDVDVISGHVVFDYDVSRELAGALAIGRKISPVAMV
MUL_2707|M.ulcerans_Agy99 LQRAKRDVDVISGHVVFDYDVSRELAGALAIGRKISPVAMV
:.* *: . :