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M. smegmatis MC2 155 MSMEG_0286 (-)

annotation: GntR-family protein transcriptional regulator
coordinates: 317634 - 318320
length: 228

TLAHTIRTALDVTLAGLQEGDPVPAERELAARFGVARETVRQALHELLVAGRIERRGRGTVVARPKLVHA
LSLQSYTEGAQTVGRTPGRMLVTREIIEASTELASGLDIATGAPVLHLERVLLADDQRIGLESTYLAAAR
FGRFEHDFDPATSLYAAIRATGVEFASATERIETALPTPREATLLECTTALPMLLLNRCSVDTDGVAIEV
VRALYRGDRVAFETVLT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0286--100% (228)GntR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_0650-1e-5653.39% (221) GntR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_4659-2e-1829.38% (211) GntR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0816c-1e-1330.56% (216) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_2603-2e-1729.46% (224) UbiC transcription regulator-associated domain-containing
M. tuberculosis H37RvRv0792c-1e-1330.56% (216) GntR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1498c-6e-7866.37% (223) GntR family transcriptional regulator
M. marinum MMMAR_2560-9e-1531.03% (232) GntR family transcriptional regulator
M. avium 104MAV_5032-8e-1731.08% (222) GntR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_3932-7e-1934.62% (208) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_0525-1e-1429.19% (209) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_0056-2e-8875.34% (223) UbiC transcription regulator-associated domain-containing

CLUSTAL 2.0.9 multiple sequence alignment


Mb0816c|M.bovis_AF2122/97           MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv        MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M               MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MSMEG_0286|M.smegmatis_MC2_155      -------------------------MTLAHTIRTALDVTLAGLQEGDPVP
Mvan_0056|M.vanbaalenii_PYR-1       -----------------------MNVPKPYLVRTGLDGILDGLQEGDPFP
MAB_1498c|M.abscessus_ATCC_199      -------------------MTADVRLPKHYQVRTELEHILSALNEGDPVP
Mflv_2603|M.gilvum_PYR-GCK          -----------MPLTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRFE
MUL_0525|M.ulcerans_Agy99           ------MEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRLP
TH_3932|M.thermoresistible__bu      -----MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR-PGDRLP
MAV_5032|M.avium_104                ----------------------------MLRSQILEGAYGGLAAARPALP
                                                                                    . 

Mb0816c|M.bovis_AF2122/97           SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPV-------
Rv0792c|M.tuberculosis_H37Rv        SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPV-------
MMAR_2560|M.marinum_M               TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLGTFVAEPV-------
MSMEG_0286|M.smegmatis_MC2_155      AERELAARFGVARETVRQALHELLVAGRIERR-GRGTVVARPK-------
Mvan_0056|M.vanbaalenii_PYR-1       PERELAARFGVARETVRQALHELLVEGRIERR-GRGTVVSRPK-------
MAB_1498c|M.abscessus_ATCC_199      PERDLAERFAVSRETVRQALHELLVEGRIERR-GRGTVVAAPK-------
Mflv_2603|M.gilvum_PYR-GCK          NELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVGTQVVQN--------
MUL_0525|M.ulcerans_Agy99           SEAELIEYFGVARMTVRQAVQELRTEGLVISEHGRGVFVRPAPPIRWLAS
TH_3932|M.thermoresistible__bu      SEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVARQPVR-----
MAV_5032|M.avium_104                SESALAAELGVSRNAIREALELLRGEGLITRVQGSGTFVTGAK-------
                                     *  *     : * : * *:  *   * :    * *  *           

Mb0816c|M.bovis_AF2122/97           ----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL--
Rv0792c|M.tuberculosis_H37Rv        ----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL--
MMAR_2560|M.marinum_M               ----KQDLESGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGR--
MSMEG_0286|M.smegmatis_MC2_155      ----LVHALS-LQSYTEGAQTVGRTPGRMLVTREIIEASTELASGLDIAT
Mvan_0056|M.vanbaalenii_PYR-1       ----LVQPLS-LRSYTEGAQRMGRTPGRLLVTWENITVDAEIAAALDVSP
MAB_1498c|M.abscessus_ATCC_199      ----LLQPLS-LRSYTEGAQSQGRTPGRLLVTWENITGDADLCRDLGIRG
Mflv_2603|M.gilvum_PYR-GCK          ----PVHRRVELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAE
MUL_0525|M.ulcerans_Agy99           DRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLRLTA
TH_3932|M.thermoresistible__bu      ----YRLSATRDASFTRGMRELGHPVRIEVLGAETTRCRR---LRTELHT
MAV_5032|M.avium_104                ----LRQDLNRLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPE
                                                                  :                   

Mb0816c|M.bovis_AF2122/97           -VEVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAM
Rv0792c|M.tuberculosis_H37Rv        -VEVLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAM
MMAR_2560|M.marinum_M               -SEVLRIQRRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTM
MSMEG_0286|M.smegmatis_MC2_155      GAPVLHLERVLLADDQRIGLESTYLA-----AARFGRFEHDFDPATSLYA
Mvan_0056|M.vanbaalenii_PYR-1       SARVMHLERVLLADDVRIGLESTYLP-----RHRFGDLEQHFDPTTSLYS
MAB_1498c|M.abscessus_ATCC_199      GSTVIHLERVLLADGAKLGLESTYLA-----KARFAELRNTFDPSTSLYA
Mflv_2603|M.gilvum_PYR-GCK          GREVASIQRLRCANGEPLALMTNHLP-------ADIAPDAEELGNIGLYQ
MUL_0525|M.ulcerans_Agy99           DDEVVVRSRRYLADGKPVETATSYIP---VAFAQGTKIEQTDTGPGGIYA
TH_3932|M.thermoresistible__bu      AGEVLTTTTLRHVDGQPWSVSVTSIA-----LDRFPGIAQQWSGSTSLFD
MAV_5032|M.avium_104                NAPILFIERLRSVGGLPLSLDTTSLR-------IGAIRIDADLDKQDVFA
                                       :         ..         :                         

Mb0816c|M.bovis_AF2122/97           WERR-LGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDG
Rv0792c|M.tuberculosis_H37Rv        WERR-LGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDG
MMAR_2560|M.marinum_M               WEQR-LGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGD
MSMEG_0286|M.smegmatis_MC2_155      AIRA-TGVEFASATERIETALPTPREATLLECTTALPMLLLNRCSVDTDG
Mvan_0056|M.vanbaalenii_PYR-1       AIRA-RGVKFGSATERIETVLPSPREAELLESTTAMPMLLLNRRSVDVDG
MAB_1498c|M.abscessus_ATCC_199      AIRA-LGVQFGSAVERIETVLASPREASLLDTSIAMPMLLMNRRTLDTDG
Mflv_2603|M.gilvum_PYR-GCK          ALRA-RGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMARTAFDDSG
MUL_0525|M.ulcerans_Agy99           RFEE-AGHTLARFNEEVGARMPTPEERRALQLPPGAPVLTVVRTAYDTKD
TH_3932|M.thermoresistible__bu      FLWQTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHG
MAV_5032|M.avium_104                LIEQELGERLGWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDG
                                          *  :      . :  .       *      *:* :        .

Mb0816c|M.bovis_AF2122/97           KPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv        KPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MMAR_2560|M.marinum_M               KPLEVVLFHHRPERYEFCVTLPRTMPGQRAGMTER----
MSMEG_0286|M.smegmatis_MC2_155      VAIEVVRALYRGDRVAFETVLT-----------------
Mvan_0056|M.vanbaalenii_PYR-1       VPIEVVRALYRGDRVAFEATLDDR---------------
MAB_1498c|M.abscessus_ATCC_199      RPIERVRSLFRGDRVAFEAVLKE----------------
Mflv_2603|M.gilvum_PYR-GCK          AAVEFGNHCYRASRYYFDTTLVDR---------------
MUL_0525|M.ulcerans_Agy99           VAVEVCDTVKVASAYLLEYDFSAR---------------
TH_3932|M.thermoresistible__bu      APVAVVRHRFRGDRVELTVDLA-----------------
MAV_5032|M.avium_104                TPFDLETVRYRGDRCSLVTTATREDAPPQ----------
                                     ..         .   :