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HLEGKKVVVVGGSAGIGRRVAADVVDHGGSAVVVGHSKARVDETLDDLVNRGGDAWGISAELTDRDAVTD IQRVLGEQHRDATLLVNAAGFFIPKPFLEYGQLDYDAYMELNYALFFLTQTVVRGMIAGGDGGSIVNIGS MWAHQALGVTPSTGHSMQKAGLHALTHNLAIELARHKIRVNAVSPAAVRTPALQRWFPTDEIDATLGEFA PLHPLGRVGTPTDIAGAIRYLLSDESSWITGMILNVDGGFTAGRN*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4440 | - | - | 100% (256) | glucose-1-dehydrogenase |
M. smegmatis MC2 155 | MSMEG_4419 | - | e-105 | 71.54% (253) | glucose-1-dehydrogenase |
M. smegmatis MC2 155 | MSMEG_6753 | - | 4e-27 | 32.67% (251) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1963c | - | 3e-29 | 30.56% (252) | short chain dehydrogenase |
M. gilvum PYR-GCK | Mflv_0661 | - | 1e-25 | 30.36% (247) | short-chain dehydrogenase/reductase SDR |
M. tuberculosis H37Rv | Rv1928c | - | 3e-29 | 30.56% (252) | short chain dehydrogenase |
M. leprae Br4923 | MLBr_02565 | fabG | 4e-18 | 31.08% (251) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. abscessus ATCC 19977 | MAB_4680c | - | 4e-27 | 35.09% (265) | putative short-chain dehydrogenase/reductase |
M. marinum M | MMAR_0629 | - | 3e-27 | 34.39% (253) | dehydrogenase |
M. avium 104 | MAV_2775 | - | 5e-28 | 32.02% (253) | short chain dehydrogenase |
M. thermoresistible (build 8) | TH_3505 | - | 1e-29 | 36.90% (252) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_0336 | - | 7e-23 | 31.72% (268) | short chain dehydrogenase |
M. vanbaalenii PYR-1 | Mvan_0489 | - | 1e-25 | 30.36% (247) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment Mb1963c|M.bovis_AF2122/97 -------------------------------------------------- Rv1928c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_2775|M.avium_104 -------------------------------------------------- MSMEG_4440|M.smegmatis_MC2_155 -------------------------------------------------- TH_3505|M.thermoresistible__bu -------------------------------------------------- MMAR_0629|M.marinum_M -------------------------------------------------- Mflv_0661|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0489|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4680c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0336|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02565|M.leprae_Br4923 MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI Mb1963c|M.bovis_AF2122/97 -------------------------------------------------- Rv1928c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_2775|M.avium_104 -------------------------------------------------- MSMEG_4440|M.smegmatis_MC2_155 -------------------------------------------------- TH_3505|M.thermoresistible__bu -------------------------------------------------- MMAR_0629|M.marinum_M -------------------------------------------------- Mflv_0661|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0489|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4680c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0336|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02565|M.leprae_Br4923 GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK Mb1963c|M.bovis_AF2122/97 -------------------------------------------------- Rv1928c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_2775|M.avium_104 -------------------------------------------------- MSMEG_4440|M.smegmatis_MC2_155 -------------------------------------------------- TH_3505|M.thermoresistible__bu -------------------------------------------------- MMAR_0629|M.marinum_M -------------------------------------------------- Mflv_0661|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0489|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_4680c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0336|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02565|M.leprae_Br4923 GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK Mb1963c|M.bovis_AF2122/97 -------------------------------------------------- Rv1928c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_2775|M.avium_104 -------------------------------------------------- MSMEG_4440|M.smegmatis_MC2_155 -------------------------------------------------- TH_3505|M.thermoresistible__bu -------------------------------------------------- MMAR_0629|M.marinum_M -------------------------------------------------- Mflv_0661|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0489|M.vanbaalenii_PYR-1 ------------------------------------------MREVRPFT MAB_4680c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_0336|M.ulcerans_Agy99 -------------------------------------------------- MLBr_02565|M.leprae_Br4923 ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD Mb1963c|M.bovis_AF2122/97 --MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDAL Rv1928c|M.tuberculosis_H37Rv --MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAIAARHLDAL MAV_2775|M.avium_104 ----MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAIAARDFEAL MSMEG_4440|M.smegmatis_MC2_155 --------MHLEGKKVVVVGGSAGIGRRVAADVVDHGGSAVVVGHSKARV TH_3505|M.thermoresistible__bu -LTIAPADILLTDRVAVVTGGGAGLGRGIAAGFAAFGARVAIWERDPDSC MMAR_0629|M.marinum_M ----------MAGLTALITGATSGIGRATAHGLAELGATVLVSGRDEARG Mflv_0661|M.gilvum_PYR-GCK -------MTAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADT-DGEG Mvan_0489|M.vanbaalenii_PYR-1 NRRRVSAVKAGDRRVAIVTAAAAGIGKAIALRWCREGGCCVMADT-DGEG MAB_4680c|M.abscessus_ATCC_199 -MNGNSALLQG--KNVIVTGGARGLGAAFSRHIVSQGGRVVIADVLDGDG MUL_0336|M.ulcerans_Agy99 ------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVIADVEEERG MLBr_02565|M.leprae_Br4923 STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE .::... *:* *. Mb1963c|M.bovis_AF2122/97 EKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELG-GIDIAVCNA Rv1928c|M.tuberculosis_H37Rv EKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELG-GIDIAVCNA MAV_2775|M.avium_104 QRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELG-GIDIAVCNA MSMEG_4440|M.smegmatis_MC2_155 DETLDDLVNRG-GDAWGISAELTDRDAVTDIQRVLGEQHR-DATLLVNAA TH_3505|M.thermoresistible__bu ARTAEEIG------ALGIVTDVRDSAAVSAALRQTTEQLG-SPTILVNNA MMAR_0629|M.marinum_M REVVDEVTARG-GRGIFLAAELRDVTGVRNLATAAADAGAGKVDILINSA Mflv_0661|M.gilvum_PYR-GCK LDAAVHELAESGAAVCGVAGDVCLSDVANSVVERALTEFG-RLDTLFNVV Mvan_0489|M.vanbaalenii_PYR-1 LDAAVHELAESGAAVCGVAGDVCLSDVANSVVERALTEFG-RLDTLFNVV MAB_4680c|M.abscessus_ATCC_199 RQLA----AELGDAARFTHLDVTDAEQWRELIDTTLAGFG-TITGLVNNA MUL_0336|M.ulcerans_Agy99 ESLA----AALGADAMFCRTDVSQPEQVAAVVAAAVDNFG-GLHVMVNNA MLBr_02565|M.leprae_Br4923 ALDETANRVGG----TTLSLDVTADDAVDKITEHLHDYQGGHADILVNNA :: . . Mb1963c|M.bovis_AF2122/97 GII--TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQGGVII Rv1928c|M.tuberculosis_H37Rv GII--TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQGGVII MAV_2775|M.avium_104 GII--SVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQGRGGAII MSMEG_4440|M.smegmatis_MC2_155 GFF--IPKPFLEYGQLDYDAYMELNY-ALFFLTQTVVRGMIAGGDGGSIV TH_3505|M.thermoresistible__bu GGT--FSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAGQPGSIV MMAR_0629|M.marinum_M GAF--PFGPTADTSPDDFDAVFALNVRAPYFLVGALAPTMAKRGR-GSIV Mflv_0661|M.gilvum_PYR-GCK GGS--LARNVEEISEEQWRSQIDMNLGSVFQMSKPVIPLLRQGGG-GSIV Mvan_0489|M.vanbaalenii_PYR-1 GGS--LARNVEEISEEQWRSQIDMNLGSVFQMSKPVIPLLRQGGG-GSIV MAB_4680c|M.abscessus_ATCC_199 GIS--SAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGC-GSIV MUL_0336|M.ulcerans_Agy99 GVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHGG-GSIV MLBr_02565|M.leprae_Br4923 GIT--RDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKG-GRVI * : : * * :: Mb1963c|M.bovis_AF2122/97 NTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVNSVSPG Rv1928c|M.tuberculosis_H37Rv NTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVNSVSPG MAV_2775|M.avium_104 TTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRVNSVSPG MSMEG_4440|M.smegmatis_MC2_155 NIGSMWAHQALGVTPSTGHSMQKAGLHALTHNLAIELARHKIRVNAVSPA TH_3505|M.thermoresistible__bu NITSIEG--ARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNAIAPD MMAR_0629|M.marinum_M NVTTMVA--EFGAAGTGLYGASKAAIALLTKSWAAEYGPSGVRVNAVSPG Mflv_0661|M.gilvum_PYR-GCK NVASTAG--ILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIAPG Mvan_0489|M.vanbaalenii_PYR-1 NVASTAG--ILAENRCSAYSASKGGVVLLTKNMALDFARDNIRVNAIAPG MAB_4680c|M.abscessus_ATCC_199 NISSAAG--LVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVHPG MUL_0336|M.ulcerans_Agy99 NLTSIGG--IQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNAIAPG MLBr_02565|M.leprae_Br4923 VLSSMAG--IAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPG : . : * .: :: * . : :*:: * Mb1963c|M.bovis_AF2122/97 YILTELVEPYTEY-------------QPLWEPKIPLGRLGRPEELAGLYL Rv1928c|M.tuberculosis_H37Rv YILTELVEPYTEY-------------QPLWEPKIPLGRLGRPEELAGLYL MAV_2775|M.avium_104 YIRTELVEPLHEY-------------HRQWQPKIPLGRMGRPDELAGIYL MSMEG_4440|M.smegmatis_MC2_155 AVRTPALQRWFPTDE-------IDATLGEFAPLHPLGRVGTPTDIAGAIR TH_3505|M.thermoresistible__bu IAVTEGLQRMSP-----------DGIPPEVGHAIPLGRPGHVDEIAGAAV MMAR_0629|M.marinum_M PTRTEGTVEMGE-------------ALDQLAAAAPAGRPADPTEIASTIV Mflv_0661|M.gilvum_PYR-GCK GTRTPRIERFLAEH---------PEHASMMVDLCAMQRFAGPDEIAAPAV Mvan_0489|M.vanbaalenii_PYR-1 GTRTPRIERFLAEH---------PEHASMMVDLCAMQRFAGPDEIAAPAV MAB_4680c|M.abscessus_ATCC_199 VIYTPMTAKEGFRE---------GEGN---MPIAAMGRVGNADEVAGAVA MUL_0336|M.ulcerans_Agy99 NIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIAEAAL MLBr_02565|M.leprae_Br4923 FIETQMTAAIPLAT------------REVGRRLNSLLQGGLPVDVAETIA * . : . ::* Mb1963c|M.bovis_AF2122/97 YLASEASSYMTGSDIVIDGGYTCP-------------------- Rv1928c|M.tuberculosis_H37Rv YLASEASSYMTGSDIVIDGGYTCP-------------------- MAV_2775|M.avium_104 YLASAASSYMTGSDIVIDGGYSCP-------------------- MSMEG_4440|M.smegmatis_MC2_155 YLLSDESSWITGMILNVDGGFTAG-------RN----------- TH_3505|M.thermoresistible__bu FLASEMSSYITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR MMAR_0629|M.marinum_M YLASDAASFIHGAVVPVDGGRAAV-------------------- Mflv_0661|M.gilvum_PYR-GCK FLASPEASYITGAVLPVDGGMTAGVTFRAFEAV----------- Mvan_0489|M.vanbaalenii_PYR-1 FLASPEASYITGAVLPVDGGMTAGVTFRAFEAV----------- MAB_4680c|M.abscessus_ATCC_199 YLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ----------- MUL_0336|M.ulcerans_Agy99 YFAGERSRYVTGTVLPVDGGTVAGKVIRRSR------------- MLBr_02565|M.leprae_Br4923 YFAIPASNAVTGNVIRVCGQAMLGA------------------- :: : : * : : *