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IYERIRAVGGEFEGKKVVVVGGSAGMGRQAALDIVDRGGSAVVIGRSKRRVDDTVADVKSRGGQAWGIAA ELTDRAAVADVQTALSEHHGDATLMVNAAGFFVPKPFLDYDAESYDSYLDLNYALFFLTQTVVAGMVAQT VGGSIVNIGSMWAHQAIGATPSTAYSMQKAALHALTHNLAIELAGNGIRVNAVAPAVVKTPLYEKFIPAD EIDATLATFAPMHPLGRVGTPADVANAITFLLSDQADWITGAILNVDGGVMAGRN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4419 | - | - | 100% (266) | glucose-1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4440 | - | e-105 | 71.54% (253) | glucose-1-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 4e-31 | 32.26% (248) | 2-deoxy-D-gluconate 3-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 2e-29 | 34.50% (258) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2469 | - | 3e-28 | 34.13% (252) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 3e-29 | 34.50% (258) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-20 | 26.36% (258) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0296 | - | 2e-25 | 31.87% (251) | putative 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase |
| M. marinum M | MMAR_0629 | - | 4e-30 | 32.79% (247) | dehydrogenase |
| M. avium 104 | MAV_3962 | - | 2e-32 | 35.20% (250) | NAD-dependent epimerase/dehydratase:Short-chain |
| M. thermoresistible (build 8) | TH_2925 | - | 8e-31 | 33.47% (242) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 9e-27 | 32.56% (258) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_0325 | - | 1e-28 | 34.12% (255) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2469|M.gilvum_PYR-GCK ---------MS---SRVAVVTGG--ASGMGESTCHELGRRGHKVAVLDLN
MAV_3962|M.avium_104 --------------MRVAVVTGG--ASGMGEATCHELGRRGMKIAVLDVD
TH_2925|M.thermoresistible__bu ---------MSSEVVPVAVVTGG--ARGIGEAIAAALIDAGYRTAVIDVN
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
MAB_0296|M.abscessus_ATCC_1997 ---------------MVAVVTGAG--GGVGSRVVTTLARRHERVVAVDID
Mb2788c|M.bovis_AF2122/97 -------MTSLDLTGRTAIITGAS--RGIGLAIAQQLAAAGAHVVLTARR
Rv2766c|M.tuberculosis_H37Rv -------MTSLDLTGRTAIITGAS--RGIGLAIAQQLAAAGAHVVLTARR
MUL_2173|M.ulcerans_Agy99 -------MTSLDLTGRTAIITGAS--RGIGLAIAQRLAGAGANVVLTARK
MMAR_0629|M.marinum_M ------------MAGLTALITGAT--SGIGRATAHGLAELGATVLVSGRD
Mvan_0325|M.vanbaalenii_PYR-1 -----MNTTAATLSGRTALVTGST--SGLGAGIAEALADAGAHVVITGRT
MSMEG_4419|M.smegmatis_MC2_155 MIYERIRAVGGEFEGKKVVVVGGS--AGMGRQAALDIVDRGGSAVVIGRS
* :.
Mflv_2469|M.gilvum_PYR-GCK GEAAQRVAEELRADGVT--ALGIAADVTDRAAVEDAFAKVRTELGPVHIL
MAV_3962|M.avium_104 EHAAQRVTDDLRTGGAT--ALGVGADVTDRAAVEQAFAKVRSELGPVTVL
TH_2925|M.thermoresistible__bu EKAITRAADSDAARQGK--LIPLQLSITDRPAVERAMGELADAHGPIRAL
MLBr_01807|M.leprae_Br4923 VADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVL
MAB_0296|M.abscessus_ATCC_1997 EVAIKQLVEYAADEGLD--VIGQILDITDDTAVAVGVSDIESRVGPITAL
Mb2788c|M.bovis_AF2122/97 QEAADEAAAQVGDRALG-----VGAHAVDEDAARRCVDLTLERFGSVDIL
Rv2766c|M.tuberculosis_H37Rv QEAADEAAAQVGDRALG-----VGAHAVDEDAARRCVDLTLERFGSVDIL
MUL_2173|M.ulcerans_Agy99 QESADAAAAEVGERAVG-----VGAHAVDEEAARGCVDLALERFGSVDIL
MMAR_0629|M.marinum_M EARGREVVDEVTARGGRGIFLAAELRDVTG-VRNLATAAADAGAGKVDIL
Mvan_0325|M.vanbaalenii_PYR-1 RARGEQVVTQIESQGGRAVFVPVDFAAGPGTITDLVVTATEALGGRLDIL
MSMEG_4419|M.smegmatis_MC2_155 KRRVDDTVADVKSRGGQAWGIAAELTDRAA-VADVQTALSEHHG-DATLM
. :
Mflv_2469|M.gilvum_PYR-GCK VTSAG-LVDFAPFLDISPQLWQRLIDVNLNGTFHCAQAAIPDMLAAGWGR
MAV_3962|M.avium_104 VTSAG-MFGFSPFLDITAESWSRIIDVNLTGTFHCCQVALPDMVAANWGR
TH_2925|M.thermoresistible__bu VNNAG-MTLPGSFLDQTDEDWDRIVDVNLKGTFVMSQVVARQMVEERTGA
MLBr_01807|M.leprae_Br4923 VANAG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGR
MAB_0296|M.abscessus_ATCC_1997 VNGAG-VLRTGAAVEFSDADWARTFDVNVRAPFVLSREVARRMIPRRAGS
Mb2788c|M.bovis_AF2122/97 INNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGA
Rv2766c|M.tuberculosis_H37Rv INNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEHGGA
MUL_2173|M.ulcerans_Agy99 INNAGTNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGEHGGV
MMAR_0629|M.marinum_M IN-SAGAFPFGPTADTSPDDFDAVFALNVRAPYFLVGALAPTMAKRGRGS
Mvan_0325|M.vanbaalenii_PYR-1 VNNVATLVQPAPTADVTAEEITTAFGVSVATPFLLTGLIAPAMVQRGDGA
MSMEG_4419|M.smegmatis_MC2_155 VN-AAGFFVPKPFLDYDAESYDSYLDLNYALFFLTQTVVAGMVAQTVGGS
: . . :. *
Mflv_2469|M.gilvum_PYR-GCK IVMISSSSA--QRGSPGMAHYAASKGALISLTRSLAREYGAAGITVNNIP
MAV_3962|M.avium_104 IVMISSSSA--QRGSPFAAHYAASKGAVITLTKSLAREYAPHGITVNNIP
TH_2925|M.thermoresistible__bu IVNISSVSA--HGVRTGPPAYAAAKAGVEGLSRLMAVQLGPSGIRVNTVV
MLBr_01807|M.leprae_Br4923 YIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVA
MAB_0296|M.abscessus_ATCC_1997 VVTVASNAA--LVARKGMTAYAASKAAANAFTKSLGLELAEYGIRCNVVA
Mb2788c|M.bovis_AF2122/97 VVNTASIGG--MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
Rv2766c|M.tuberculosis_H37Rv VVNTASIGG--MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNAIC
MUL_2173|M.ulcerans_Agy99 VINTASIGG--MHQSPAMGMYNATNAALIHVTKQLALELSPR-VRVNAIC
MMAR_0629|M.marinum_M IVNVTTMVA--EFGAAGTGLYGASKAAIALLTKSWAAEYGPSGVRVNAVS
Mvan_0325|M.vanbaalenii_PYR-1 IVNIGSISG--IIGAAGSALYGATKASVHLLTKAWAAEYGPSGVRVNAVA
MSMEG_4419|M.smegmatis_MC2_155 IVNIGSMWAHQAIGATPSTAYSMQKAALHALTHNLAIELAGNGIRVNAVA
: : . * :.. .:: . : . : * :
Mflv_2469|M.gilvum_PYR-GCK PSGIETPMQLQSQAAGFLPPNEQ-----MAASIPVGHLGTGDDIAAAVGF
MAV_3962|M.avium_104 PSGIETPMQHQGQAAGYLPSNEQ-----IAANIPLGYLGTGADIAAAVGF
TH_2925|M.thermoresistible__bu VGTTATPWLLSRKTDEELAT--------MRESTLLDRLGEPEDVAATVAF
MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDSKYQEAA---------LQAIPLGRIGAVEEIAGAVSF
MAB_0296|M.abscessus_ATCC_1997 PGSTDTPMLRAMLGDSSDAGLVAGSLGDYKPGIPLGRVAQPQHIADAVAF
Mb2788c|M.bovis_AF2122/97 PGVVRTRLAEALWKDHEDPL---------AATIALGRIGEPADIASAVAF
Rv2766c|M.tuberculosis_H37Rv PGVVRTRLAEALWKDHEDPL---------AATIALGRIGEPADIASAVAF
MUL_2173|M.ulcerans_Agy99 PGVVRTKLAEALWKDHEDPL---------AANIALGRIGEPVDVAEAVGF
MMAR_0629|M.marinum_M PGPTRT------EGTVEMGEALDQ----LAAAAPAGRPADPTEIASTIVY
Mvan_0325|M.vanbaalenii_PYR-1 PGPIAT------ERTREFGDAIAP----VLARVPSHRMSTVAEVASAVVF
MSMEG_4419|M.smegmatis_MC2_155 PAVVKTPLYEKFIPADEIDATLAT----FAPMHPLGRVGTPADVANAITF
. * . .:* :: :
Mflv_2469|M.gilvum_PYR-GCK LCSEQAGFITGQTLGVNGGSVMA-----------------
MAV_3962|M.avium_104 LTSDEARYITGQVLGVNGGAVMLTVRIR------------
TH_2925|M.thermoresistible__bu LCSPAARHVTGQLVSVSGGQWMP-----------------
MLBr_01807|M.leprae_Br4923 LASEDAGYISGAVIPVDGGLGMGH----------------
MAB_0296|M.abscessus_ATCC_1997 LLSDQAAHITMHTLVVDGGATLGV----------------
Mb2788c|M.bovis_AF2122/97 LVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH----
Rv2766c|M.tuberculosis_H37Rv LVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH----
MUL_2173|M.ulcerans_Agy99 LVSDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS----
MMAR_0629|M.marinum_M LASDAASFIHGAVVPVDGGRAAV-----------------
Mvan_0325|M.vanbaalenii_PYR-1 LAGPEAANIHGTILSVDGGATAVRDEPAAVTKLGNHPHPG
MSMEG_4419|M.smegmatis_MC2_155 LLSDQADWITGAILNVDGGVMAGRN---------------
* . * : : :.**