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MVAVVTGAGGGVGSRVVTTLARRHERVVAVDIDEVAIKQLVEYAADEGLDVIGQILDITDDTAVAVGVSD IESRVGPITALVNGAGVLRTGAAVEFSDADWARTFDVNVRAPFVLSREVARRMIPRRAGSVVTVASNAAL VARKGMTAYAASKAAANAFTKSLGLELAEYGIRCNVVAPGSTDTPMLRAMLGDSSDAGLVAGSLGDYKPG IPLGRVAQPQHIADAVAFLLSDQAAHITMHTLVVDGGATLGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0296 | - | - | 100% (252) | putative 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2723c | - | 3e-27 | 30.24% (248) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_3844c | - | 3e-24 | 32.33% (266) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 4e-28 | 33.33% (246) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2501 | - | 5e-32 | 35.48% (248) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1941 | - | 4e-28 | 33.33% (246) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-28 | 33.06% (248) | 3-oxoacyl- |
| M. marinum M | MMAR_0402 | - | 2e-29 | 35.06% (251) | short chain dehydrogenase |
| M. avium 104 | MAV_1395 | - | 2e-32 | 33.73% (252) | 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0294 | fabG | 3e-32 | 33.33% (249) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_2925 | - | 1e-36 | 35.77% (246) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 7e-29 | 33.20% (250) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_4185 | - | 1e-31 | 33.33% (249) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2501|M.gilvum_PYR-GCK ----------MKN----------AVVTGGASGIGAAVVERLRADGLQVAT
MUL_0315|M.ulcerans_Agy99 ----------MRPDSSPSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MSMEG_0294|M.smegmatis_MC2_155 ----------MNR---------VAVVTGGASGMGEATCHELGRRGHKVAV
Mvan_4185|M.vanbaalenii_PYR-1 ----------MTR---------VAVVTGGASGMGEATCHELGRRGCKVAV
MAV_1395|M.avium_104 ----------------------MAVVTGGGSGIGRAIVERLAHDGHRVAV
MAB_0296|M.abscessus_ATCC_1997 ---------------------MVAVVTGAGGGVGSRVVTTLARRHERVVA
TH_2925|M.thermoresistible__bu ---------------MSSEVVPVAVVTGGARGIGEAIAAALIDAGYRTAV
Mb1976|M.bovis_AF2122/97 -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MMAR_0402|M.marinum_M ----------------MTGGGRVALVTGAAGGQGWAIVQRLRAEGHSVAA
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:***. * * * .
Mflv_2501|M.gilvum_PYR-GCK IDLNPGDAK-------------FSYAADVTDRSAVDAALDEIRAELGPVT
MUL_0315|M.ulcerans_Agy99 LDLKTPDGG-------------LAFSADVTNRSQVDAALAAIRQRLGPVT
MSMEG_0294|M.smegmatis_MC2_155 LDVDVDAAQRVTDHLRSEGVTAFAVGADVTDRAAVEEAFAKVRSELGAVG
Mvan_4185|M.vanbaalenii_PYR-1 LDLDGQAAQRVAEELRGDGVPALGVAADVTDRAAVEDAFAKVRTELGPVH
MAV_1395|M.avium_104 LDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGSVQ
MAB_0296|M.abscessus_ATCC_1997 VDIDEVAIKQLVEYAADEGLDVIGQILDITDDTAVAVGVSDIESRVGPIT
TH_2925|M.thermoresistible__bu IDVNEKAITRAADSDAARQGKLIPLQLSITDRPAVERAMGELADAHGPIR
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIG---CGAAACRVDVSDEQQIIAMVDACVAAFGGVD
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIG---CGAAACRVDVSDEQQIIAMVDACVAAFGGVD
MMAR_0402|M.marinum_M CDLRADRLDALVAESGD--DAVISLALDVTDEAQWQEAVERAVTRFGALT
MLBr_01807|M.leprae_Br4923 THRASVVPD-----------WFFGVECDVTDNDAIGAAFKAVEEHQGPVE
. .::: . * :
Mflv_2501|M.gilvum_PYR-GCK VLVNAAGLDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAGWG
MUL_0315|M.ulcerans_Agy99 ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MSMEG_0294|M.smegmatis_MC2_155 ILVTSAGMFGYASFADITEQSWAQMIDVNLSGTFRCCQVALPDMVDAGWG
Mvan_4185|M.vanbaalenii_PYR-1 ILVTSAGLVDFAPFLEISPDRWQRLIEVNLNGTFHCAQVAIPDMLAAGWG
MAV_1395|M.avium_104 VLVTSAAITGFKPFAEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWG
MAB_0296|M.abscessus_ATCC_1997 ALVNGAGVLRTGAAVEFSDADWARTFDVNVRAPFVLSREVARRMIPRRAG
TH_2925|M.thermoresistible__bu ALVNNAGMTLPGSFLDQTDEDWDRIVDVNLKGTFVMSQVVARQMVEERTG
Mb1976|M.bovis_AF2122/97 KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Rv1941|M.tuberculosis_H37Rv KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
MMAR_0402|M.marinum_M ALINNAGVLHRAALVDETAAGFESAWRVNCLGAFLGMRAALGALSAAEGP
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
*: *.: : : :* . : : . :
Mflv_2501|M.gilvum_PYR-GCK RIVNISSSSTHSGQPYMSPYVAAKSAVNGLTKSLALEYGPAGITVNAVPP
MUL_0315|M.ulcerans_Agy99 RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MSMEG_0294|M.smegmatis_MC2_155 RIVLISSSSAQRGTPFAAHYAASKGALLTLTKSLAREYAKHGITVNNIPP
Mvan_4185|M.vanbaalenii_PYR-1 RIVMISSSSAQRGSPGMAHYAASKGALISFTRSLAREYGPAGITVNNVPP
MAV_1395|M.avium_104 RVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAAHGITANTVPP
MAB_0296|M.abscessus_ATCC_1997 SVVTVASNAALVARKGMTAYAASKAAANAFTKSLGLELAEYGIRCNVVAP
TH_2925|M.thermoresistible__bu AIVNISSVSAHGVRTGPPAYAAAKAGVEGLSRLMAVQLGPSGIRVNTVVV
Mb1976|M.bovis_AF2122/97 AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
Rv1941|M.tuberculosis_H37Rv AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
MMAR_0402|M.marinum_M VIVNICSTGAIRPFPHHCAYGAAKWALRGLTQTAAAELAPAGIRVNAVFP
MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
: : * * :* . ::: . : .* * :
Mflv_2501|M.gilvum_PYR-GCK GFIDTPMLRKAEQ----RGFLGDTEQQIQQTP-------VRRMGRPEDIA
MUL_0315|M.ulcerans_Agy99 GFIDTPMLRNAAA----QGHLGDIEQNIARTP-------VRRIGKPEDIA
MSMEG_0294|M.smegmatis_MC2_155 SGIETPMQHASQA----AGYLPPNETIAANIP-------LGRLGAPADIA
Mvan_4185|M.vanbaalenii_PYR-1 SGIETPMQHQSQA----AGFLPPNEQMAASIP-------VGHLGTGDDIA
MAV_1395|M.avium_104 FSVDTPMLRAAQE----AGNLPPVKYLAKASP-------VGRLGTGEDIA
MAB_0296|M.abscessus_ATCC_1997 GSTDTPMLRAMLG------DSSDAGLVAGSLGDYKPGIPLGRVAQPQHIA
TH_2925|M.thermoresistible__bu GTTATPWLLSRKT------DEELATMRESTL--------LDRLGEPEDVA
Mb1976|M.bovis_AF2122/97 AFVDTPMQQTAMAMFDGALGAGGARSMIARL--------QGRMAAPEEMA
Rv1941|M.tuberculosis_H37Rv AFVDTPMQQTAMAMFDGALGAGGARSMIARL--------QGRMAAPEEMA
MMAR_0402|M.marinum_M GPIATSMLD----------EPTQARLAAVSM--------FGRLGRPAEVA
MLBr_01807|M.leprae_Br4923 GFIDTEMTRAMDS--------KYQEAALQAIP-------LGRIGAVEEIA
* ::. .:*
Mflv_2501|M.gilvum_PYR-GCK AACAFFISEEAGYITGQILGVNGGRNT---
MUL_0315|M.ulcerans_Agy99 AACAFLVSEEAGYITGQILGVNGGRNT---
MSMEG_0294|M.smegmatis_MC2_155 AAVGFLCSEEAGFITGQTLGVNGGSVM---
Mvan_4185|M.vanbaalenii_PYR-1 AAVGFLCSEEAGFITGQTLGVNGGSVMA--
MAV_1395|M.avium_104 AACAFLCSDEAGYITGQIIGVNGGEVI---
MAB_0296|M.abscessus_ATCC_1997 DAVAFLLSDQAAHITMHTLVVDGGATLGV-
TH_2925|M.thermoresistible__bu ATVAFLCSPAARHVTGQLVSVSGGQWMP--
Mb1976|M.bovis_AF2122/97 GIVVFLLSDDASMITGTTQIADGGTIAALW
Rv1941|M.tuberculosis_H37Rv GIVVFLLSDDASMITGTTQIADGGTIAALW
MMAR_0402|M.marinum_M DAVAFLVSENSSFITGSELVVDGGQCLQVP
MLBr_01807|M.leprae_Br4923 GAVSFLASEDAGYISGAVIPVDGGLGMGH-
*: * : :: ..**