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M. thermoresistible (build 8) TH_2925 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 2987928 - 2988677
length: 250

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2925--100% (250)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3102-4e-4140.74% (243) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3693-4e-3535.68% (241) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1385fabG2e-3233.74% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2501-6e-4040.00% (245) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1350fabG2e-3233.74% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG11e-2829.92% (244) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0296-1e-3635.77% (246) putative 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
M. marinum MMMAR_4715-4e-3739.42% (241) 3-oxoacyl-
M. avium 104MAV_0942-2e-3739.00% (241) 3-oxoacyl-(acyl-carrier-protein) reductase, putative
M. smegmatis MC2 155MSMEG_6538-1e-3737.76% (241) 3-oxoacyl-(acyl-carrier-protein) reductase, putative
M. ulcerans Agy99MUL_0315fabG29e-3739.00% (241) 3-oxoacyl-
M. vanbaalenii PYR-1Mvan_4157-3e-4141.22% (245) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1385|M.bovis_AF2122/97            ---MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv         ---MASLLN-----------ARTAVITGGAQGLGLAIGQRFVAEGARVVL
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mflv_2501|M.gilvum_PYR-GCK          ---MK-----------------NAVVTGGASGIGAAVVERLRADGLQVAT
Mvan_4157|M.vanbaalenii_PYR-1       ---MK-----------------NAVVTGGASGIGAAIAERLRADGMRVAT
MMAR_4715|M.marinum_M               ---MK-----------------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99           ---MRPDSS-------PSWCTITSVVTGGASGIGLAIARRLSADGTDVAT
MAV_0942|M.avium_104                ---MK-----------------TAVVTGGGSGIGLAVVERLRADGLNVAS
MSMEG_6538|M.smegmatis_MC2_155      ---MT---------------AKTALVTGGASGIGKAIAERLASDGHQVAI
TH_2925|M.thermoresistible__bu      ---MSSEVVP------------VAVVTGGARGIGEAIAAALIDAGYRTAV
MAB_0296|M.abscessus_ATCC_1997      ---------------------MVAVVTGAGGGVGSRVVTTLARRHERVVA
                                                            ::**.  *:*  :   :      .. 

Mb1385|M.bovis_AF2122/97            GDVNLEATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGGLD
Rv1350|M.tuberculosis_H37Rv         GDVNLEATEVAAKRLGG-DDVALAVRCDVTQADDVDILIRTAVERFGGLD
MLBr_01807|M.leprae_Br4923          THR---ASVVPDWFFG--------VECDVTDNDAIGAAFKAVEEHQGPVE
Mflv_2501|M.gilvum_PYR-GCK          IDLNPGDAKFS-------------YAADVTDRSAVDAALDEIRAELGPVT
Mvan_4157|M.vanbaalenii_PYR-1       IDLNPGDEKFS-------------YAADVTDRAAVDAVLSEIHTELGPVT
MMAR_4715|M.marinum_M               LDLKTPDGELA-------------FSADVTNRSQVDAALTAIRQRLGPVT
MUL_0315|M.ulcerans_Agy99           LDLKTPDGGLA-------------FSADVTNRSQVDAALAAIRQRLGPVT
MAV_0942|M.avium_104                IDLRPSDAELA-------------FTADVTDRSQVDAALSAIRAQLGPVT
MSMEG_6538|M.smegmatis_MC2_155      LDLNPGDGPHA-------------YTADVTDRAQVDGVFKAVREELGPVS
TH_2925|M.thermoresistible__bu      IDVNEKAITRAADSDAARQGKLIPLQLSITDRPAVERAMGELADAHGPIR
MAB_0296|M.abscessus_ATCC_1997      VDIDEVAIKQLVEYAADEGLDVIGQILDITDDTAVAVGVSDIESRVGPIT
                                     .                         .:*:   :   .       * : 

Mb1385|M.bovis_AF2122/97            VMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRG
Rv1350|M.tuberculosis_H37Rv         VMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMRERKRG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
Mflv_2501|M.gilvum_PYR-GCK          VLVNAAGLDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAGWG
Mvan_4157|M.vanbaalenii_PYR-1       VLVNAAGLDRFKKFLDLTFDEWQKVVDVNLNGVFHCTQAVLPDMIEAGWG
MMAR_4715|M.marinum_M               ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MUL_0315|M.ulcerans_Agy99           ILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGWG
MAV_0942|M.avium_104                VLVNAAGLDGFKKFNNITFEDWQRVIDVNLNGVFHTTQAVLPDMIEAGWG
MSMEG_6538|M.smegmatis_MC2_155      ILVNAAGLSDFTPFTDISFDHWQRVVNVNLHGVFHVVQAALPDMVAAGWG
TH_2925|M.thermoresistible__bu      ALVNNAGMTLPGSFLDQTDEDWDRIVDVNLKGTFVMSQVVARQMVEERTG
MAB_0296|M.abscessus_ATCC_1997      ALVNGAGVLRTGAAVEFSDADWARTFDVNVRAPFVLSREVARRMIPRRAG
                                     :*  **:         :  .: : . *:: . :   : .   *     *

Mb1385|M.bovis_AF2122/97            AIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAP
Rv1350|M.tuberculosis_H37Rv         AIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAIAP
MLBr_01807|M.leprae_Br4923          RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
Mflv_2501|M.gilvum_PYR-GCK          RIVNISSSSTHSGQPYMSPYVAAKSAVNGLTKSLALEYGPAGITVNAVPP
Mvan_4157|M.vanbaalenii_PYR-1       RIVNISSSSTHSGQPYMSPYVAAKSAVNGLTKSLALEYGPDGITVNAVPP
MMAR_4715|M.marinum_M               RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MUL_0315|M.ulcerans_Agy99           RIVNISSSSTHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAVPP
MAV_0942|M.avium_104                RIVNISSSSTHSGAPYMSHYVAAKSAVNGLTKSLALEYGPKGITVNAVPP
MSMEG_6538|M.smegmatis_MC2_155      RIVNISSSSTHSGVPYMSSYVSAKSAVNGLTKSLALEFGPAGITVNAVPP
TH_2925|M.thermoresistible__bu      AIVNISSVSAHGVRTGPPAYAAAKAGVEGLSRLMAVQLGPSGIRVNTVVV
MAB_0296|M.abscessus_ATCC_1997      SVVTVASNAALVARKGMTAYAASKAAANAFTKSLGLELAEYGIRCNVVAP
                                      : :.*          . * ::*:.  .:::  . : .  .*  *.:  

Mb1385|M.bovis_AF2122/97            GLIRSAMTEAMPQR---------IWDQKLAEVPMGRAGEPSEVASVAVFL
Rv1350|M.tuberculosis_H37Rv         GLIRSAMTEAMPQR---------IWDQKLAEVPMGRAGEPSEVASVAVFL
MLBr_01807|M.leprae_Br4923          GFIDTEMTRAMDSK---------YQEAALQAIPLGRIGAVEEIAGAVSFL
Mflv_2501|M.gilvum_PYR-GCK          GFIDTPMLRKAEQRG-----FLGDTEQQIQQTPVRRMGRPEDIAAACAFF
Mvan_4157|M.vanbaalenii_PYR-1       GFIDTPMLRKAEQRG-----FLGDTQKQIEQTPVRRMGRPEDIAAACSFL
MMAR_4715|M.marinum_M               GFIDTPMLRNAAAQG-----HLGDIEQNIARTPVRRIGKPEDIAAACAFL
MUL_0315|M.ulcerans_Agy99           GFIDTPMLRNAAAQG-----HLGDIEQNIARTPVRRIGKPEDIAAACAFL
MAV_0942|M.avium_104                GFIDTPMLRAAEKNG-----FLGDIEETIARTPVRRMGTPQDIAAACAFL
MSMEG_6538|M.smegmatis_MC2_155      GFIDTPMLRAAEARG-----ELGDIDDTIAATPVRRMGRPEDIAATCSFL
TH_2925|M.thermoresistible__bu      GTTATPWLLSRKTD--------EELATMRESTLLDRLGEPEDVAATVAFL
MAB_0296|M.abscessus_ATCC_1997      GSTDTPMLRAMLGDSSDAGLVAGSLGDYKPGIPLGRVAQPQHIADAVAFL
                                    *   :                            : * .  ..:* .  *:

Mb1385|M.bovis_AF2122/97            ASDLSSYMTGTVLDVTGGRFI--
Rv1350|M.tuberculosis_H37Rv         ASDLSSYMTGTVLDVTGGRFI--
MLBr_01807|M.leprae_Br4923          ASEDAGYISGAVIPVDGGLGMGH
Mflv_2501|M.gilvum_PYR-GCK          ISEEAGYITGQILGVNGGRNT--
Mvan_4157|M.vanbaalenii_PYR-1       ISEEAGYITGQILGVNGGRNT--
MMAR_4715|M.marinum_M               VSEEAGYITGQILGVNGGRNT--
MUL_0315|M.ulcerans_Agy99           VSEEAGYITGQILGVNGGRNT--
MAV_0942|M.avium_104                VSEEAGYITGQILGVNGGRNT--
MSMEG_6538|M.smegmatis_MC2_155      ISEEAGYITGQIIGVNGGRNT--
TH_2925|M.thermoresistible__bu      CSPAARHVTGQLVSVSGGQWMP-
MAB_0296|M.abscessus_ATCC_1997      LSDQAAHITMHTLVVDGGATLGV
                                     *  : :::   : * **