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DVGLAGKHILVTGGTRGIGRATVEKLLAEGARVSAVARTADSIAKAAESMGDPSNLRFVAADLSDESGCA SAASAALDGFGALDGVVNNASAFSIDRGHPGRAEWSELFQLKLLGYESVIQAALPHISAGGGIVNVSGIA SMRHWPQSPHVSAVNSGVESLTRHYAAELVERRIRVNVVVPGTTATDRYLGRVSRVQERDGVDAEEARRQ IDRTVPLGRPVHPEEIAAAIVFLLGDVSASTTGAVLVVDGGAVVSRSAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4125 | - | - | 100% (260) | oxidoreductase, short chain dehydrogenase/reductase family protein |
| M. smegmatis MC2 155 | MSMEG_1689 | - | 1e-33 | 39.77% (259) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_4382 | - | 9e-31 | 35.04% (254) | dehydrogenase/reductase SDR family protein member 10 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 7e-24 | 29.77% (262) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_5148 | - | 5e-29 | 34.11% (258) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2766c | fabG | 7e-24 | 29.77% (262) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-17 | 29.92% (254) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0164 | - | 3e-26 | 31.91% (257) | short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0587 | - | 2e-28 | 35.34% (249) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2567 | - | 3e-26 | 33.59% (259) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2488 | - | 2e-28 | 35.57% (253) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0336 | - | 9e-27 | 33.21% (265) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1185 | - | 5e-29 | 33.99% (253) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MUL_0336|M.ulcerans_Agy99 --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MMAR_0587|M.marinum_M ---------------MGQLEGKTALVTGGNSGIGLAAAQRLAAEGAHVFL
TH_2488|M.thermoresistible__bu ----------------MEFQGLHVLVTGGTGGIGLACARAFAEAGAEVTV
Mflv_5148|M.gilvum_PYR-GCK --------------MDLGLSGKRFVVSGGTRGIGRAVVEGLLAEGASVAF
Mvan_1185|M.vanbaalenii_PYR-1 --------------MELGLEGKRFAVTGGTRGIGRAVVEGLLAEGASVAY
MSMEG_4125|M.smegmatis_MC2_155 --------------MDVGLAGKHILVTGGTRGIGRATVEKLLAEGARVSA
MAB_0164|M.abscessus_ATCC_1997 -------MNLTDFQSLYDLSGRTAIVTGGTRGIGYAIAEALGACGASVVV
MAV_2567|M.avium_104 ------------------MRGKGYVVVGGTAGMGLAAARALAREGASVVV
: . : *. *:* * . : * *
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFGSV
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQVG----DRALGVGAHAVDEDAARRCVDLTLERFGSV
MLBr_01807|M.leprae_Br4923 THR--------ASVVP----DWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAALG----ADAMFCRTDVSQPEQVAAVVAAAVDNFGGL
MMAR_0587|M.marinum_M TGRNQATIDAAVASIG----SRAHGIRADVSNIEDLARVADAIAAAGRGL
TH_2488|M.thermoresistible__bu TGR-DAGRGAAAAGAH----PRLRFIRGDLA---DLASVQNLIRYAD-AV
Mflv_5148|M.gilvum_PYR-GCK CARTPAAVEQAQAELSA-NGAAVAGAVVDVGDAAAVEAWVTQAAGMFSGL
Mvan_1185|M.vanbaalenii_PYR-1 CARTYEPVP------------GAVGTAVDVGDGAALATWVDATADAFSGL
MSMEG_4125|M.smegmatis_MC2_155 VARTADSIAKAAESMG--DPSNLRFVAADLSDESGCASAASAALDGFGAL
MAB_0164|M.abscessus_ATCC_1997 SSRKSDACTAAAKELHDKGYR-ALGVPAHMGELGDIDALVTATVDEYGGV
MAV_2567|M.avium_104 VGRDADRGKNAAEEVAAAGAASAHDLVFDVSQPGAAVAAVDEAVRLLGRL
. :
Mb2788c|M.bovis_AF2122/97 DILINNAGTNPAYG-PLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
Rv2766c|M.tuberculosis_H37Rv DILINNAGTNPAYG-PLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDM--LIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
MUL_0336|M.ulcerans_Agy99 HVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAH
MMAR_0587|M.marinum_M DVLFANAGGGEFVL--LGDITIEHFTNGFMTNVAGTLFTVQTMLP-LLNS
TH_2488|M.thermoresistible__bu DVLVNNAASFPGAL--TVEQDAESFTRTFATNVTGTYFLTAGLIPGMLAR
Mflv_5148|M.gilvum_PYR-GCK DGVVANVS-ALAIP--ETHEN---WRTTFEVDLMGTVGMVDAAMPYLLES
Mvan_1185|M.vanbaalenii_PYR-1 DGVVANVS-ALAIP--ETHEN---WHTSFDVDLMGTVNLVDAALPYLLEA
MSMEG_4125|M.smegmatis_MC2_155 DGVVNNAS-AFSID--RGHPGRAEWSELFQLKLLGYESVIQAALPHISAG
MAB_0164|M.abscessus_ATCC_1997 DIVVNAAANPVAQP--MGSYTPEALGKSFDVNVRGPVFLVQAALPHLTAS
MAV_2567|M.avium_104 DGIAVTMGTAGMMP--IDSDD-DAWDNAFHDVLLATVRSVQAALPHLAVN
. : . : : .
Mb2788c|M.bovis_AF2122/97 HGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
Rv2766c|M.tuberculosis_H37Rv HGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
MUL_0336|M.ulcerans_Agy99 GGGSIVNLTSIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNA
MMAR_0587|M.marinum_M G-ASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRVNT
TH_2488|M.thermoresistible__bu GRGSIVNITSMVATKAVPGASVYSSSKAAVESLTRSWAVEFAAHGIRVNA
Mflv_5148|M.gilvum_PYR-GCK DAGSIVTVSSVSGREVDFAAGPYGTMKAAIIHYTQGLAFKYAGQGVRANT
Mvan_1185|M.vanbaalenii_PYR-1 DSGSIVTISSVSGREIDFAAGPYGTMKAAIIHYTQGLAFKLAAQGVRANT
MSMEG_4125|M.smegmatis_MC2_155 --GGIVNVSGIASMRHWPQSPHVSAVNSGVESLTRHYAAELVERRIRVNV
MAB_0164|M.abscessus_ATCC_1997 EHASVLNVVSVAAFQYVPMLSMYAAMKATLMSFTRSMAAEYTARGIRVNA
MAV_2567|M.avium_104 GGAIVTTAAYSARSPHEPRLP-YASLKAAVATFTRGIARTHGKSGIRANS
. : :. : : * : .*
Mb2788c|M.bovis_AF2122/97 ICPG------------VVRTRLA----EALWKDHEDPLAATIALGRIGEP
Rv2766c|M.tuberculosis_H37Rv ICPG------------VVRTRLA----EALWKDHEDPLAATIALGRIGEP
MLBr_01807|M.leprae_Br4923 VAPG------------FIDTEMT----RAMDSKYQEAALQAIPLGRIGAV
MUL_0336|M.ulcerans_Agy99 IAPGNIPTPLLASSAAGLDQEQV----ERFTAQIRQTMREDRPLKREGTP
MMAR_0587|M.marinum_M VVPG-------PVETPGLKGLAP----EGQEQQLLEGEAAKVPMGRLGKP
TH_2488|M.thermoresistible__bu VAPG-------PTST---DGVAT----EWGETN--EALGRALPIGRTADP
Mflv_5148|M.gilvum_PYR-GCK VSPGNTYFP---GGVWTSIEEND-----PQLFATALALN---PTGRMATP
Mvan_1185|M.vanbaalenii_PYR-1 VSPGNTYFP---GGVWPSIEQSD-----PELFATALALN---PTGRMATP
MSMEG_4125|M.smegmatis_MC2_155 VVPGTTATDRYLGRVSRVQERDG-----VDAEEARRQIDRTVPLGRPVHP
MAB_0164|M.abscessus_ATCC_1997 LAPGTVDTYMLQQNP----------------QEIIDAMAAQSFMGRVAHT
MAV_2567|M.avium_104 VAPGAVETDALHAIRGYVAESKGYPYAEALERALVEDFGFDAALGRPGQP
: ** *
Mb2788c|M.bovis_AF2122/97 ADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv ADIASAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MLBr_01807|M.leprae_Br4923 EEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH------------
MUL_0336|M.ulcerans_Agy99 EDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR------
MMAR_0587|M.marinum_M AEIAAAVLFLASDQSSFMTGSEMFVDGGTEQL-------------
TH_2488|M.thermoresistible__bu DEIAQAVVFLASSRASFITGAVLHVDGGGIAV-------------
Mflv_5148|M.gilvum_PYR-GCK QEVANAVVFLSSPAASFITGTNLLVDG--ALTRGVQF--------
Mvan_1185|M.vanbaalenii_PYR-1 QEVANAVVFLSSAAASFITGTNLLVDG--ALTRGVQL--------
MSMEG_4125|M.smegmatis_MC2_155 EEIAAAIVFLLGDVSASTTGAVLVVDGGAVVSRSAD---------
MAB_0164|M.abscessus_ATCC_1997 DEMIGPALLLLSDAGSFITGQVIVADGGGGVQR------------
MAV_2567|M.avium_104 DEIGALIAFLLSDICAFVTGQTIYADGGAP---------------
:: : . :* : **