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QLSGYHALVTGGTAGIGRACADLLAREGARVTITGRDADRGAAAAAELGDNVRFVQADLSDLQSVKALAE QCDTADIVVNNAASFPGALTVEQDIASYERTFDTNVRGTYFLVAQLAPGMFARGRGSIVNVTSMVASKGV AGASTYSASKAAVESLTRTWAAEFGPRGVRVNSVAPGPTRTEGVEAEWGDTNEQLGKALPLGRTAQPEEI AHAVLFLCSPRASFITGSTLHADGGGAAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1689 | - | - | 100% (240) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_6753 | - | 1e-80 | 63.75% (240) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_5383 | - | 3e-42 | 41.91% (241) | dehydrogenase/reductase SDR family protein member 4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 1e-34 | 37.55% (245) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 2e-34 | 36.21% (243) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 1e-34 | 37.55% (245) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-26 | 32.76% (232) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0164 | - | 2e-34 | 38.87% (247) | short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0629 | - | 4e-56 | 49.19% (246) | dehydrogenase |
| M. avium 104 | MAV_3655 | fabG | 2e-34 | 38.08% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_2488 | - | 5e-89 | 67.50% (240) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2173 | fabG | 4e-33 | 34.85% (241) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1212 | - | 6e-92 | 70.83% (240) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2882c|M.bovis_AF2122/97 -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv -----------MMDLSQRLAGRVAVITGGGSGIGLAAGRRMRAEGATIVV
TH_2488|M.thermoresistible__bu ----------------MEFQGLHVLVTGGTGGIGLACARAFAEAGAEVTV
Mvan_1212|M.vanbaalenii_PYR-1 ----------------MELTGQTALITGGTAGIGLACAQLMAREGADVVI
MSMEG_1689|M.smegmatis_MC2_155 ----------------MQLSGYHALVTGGTAGIGRACADLLAREGARVTI
MMAR_0629|M.marinum_M ------------------MAGLTALITGATSGIGRATAHGLAELGATVLV
MAB_0164|M.abscessus_ATCC_1997 -------MNLTDFQSLYDLSGRTAIVTGGTRGIGYAIAEALGACGASVVV
Mflv_2424|M.gilvum_PYR-GCK ---------MAITASDILLTGRVAVVTGGGAGIGRGIAQGLAAFGASVAI
MAV_3655|M.avium_104 -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
MUL_2173|M.ulcerans_Agy99 -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: . ::**. *** . . : * : :
Mb2882c|M.bovis_AF2122/97 GDVDVEAG-----GAAADELSGLFVPTDVCDEDAVNGLFDGAAETYG-RI
Rv2857c|M.tuberculosis_H37Rv GDVDVEAG-----GAAADELSGLFVPTDVCDEDAVNGLFDGAAETYG-RI
TH_2488|M.thermoresistible__bu TGRDAGRG---AAAAGAH-PRLRFIRGDLADLASVQNLIRYAD-----AV
Mvan_1212|M.vanbaalenii_PYR-1 TGRDPGRG---EAAAASD-PRLRFLRCDLADRTSIESLVQQAP-----PV
MSMEG_1689|M.smegmatis_MC2_155 TGRDADRG---AAAAAELGDNVRFVQADLSDLQSVKALAEQCD-----TA
MMAR_0629|M.marinum_M SGRDEARGREVVDEVTARGGRGIFLAAELRDVTGVRNLATAAADAGAGKV
MAB_0164|M.abscessus_ATCC_1997 SSRKSDACTAAAKELHDKGYRALGVPAHMGELGDIDALVTATVDEYG-GV
Mflv_2424|M.gilvum_PYR-GCK WERDPDTC-----AAAAAAIGGLGLEVDVRDAAAVDTALDRTERELG-TV
MAV_3655|M.avium_104 TARKQEAA---DEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERFG-SV
MUL_2173|M.ulcerans_Agy99 TARKQESA---DAAAAEVGERAVGVGAHAVDEEAARGCVDLALERFG-SV
MLBr_01807|M.leprae_Br4923 THR-----------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQG-PV
: . :
Mb2882c|M.bovis_AF2122/97 DIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLA
Rv2857c|M.tuberculosis_H37Rv DIAFNNAGISPPEDNLIENTELAAWQRVQDVNLKSVYLCCRAALRHMVLA
TH_2488|M.thermoresistible__bu DVLVNNAAS--FPGALTVEQDAESFTRTFATNVTGTYFLTAGLIPGMLAR
Mvan_1212|M.vanbaalenii_PYR-1 DILVNNAAS--FPGAMTVDQDAATFQRTFDTNVGGTYFLTAAVVPAMLLR
MSMEG_1689|M.smegmatis_MC2_155 DIVVNNAAS--FPGALTVEQDIASYERTFDTNVRGTYFLVAQLAPGMFAR
MMAR_0629|M.marinum_M DILINSAGA--FPFGPTADTSPDDFDAVFALNVRAPYFLVGALAPTMAKR
MAB_0164|M.abscessus_ATCC_1997 DIVVNAAAN--PVAQPMGSYTPEALGKSFDVNVRGPVFLVQAALPHLTAS
Mflv_2424|M.gilvum_PYR-GCK SILVNNAGG--TFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAA
MAV_3655|M.avium_104 DILVNNAGTN-PAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGE
MUL_2173|M.ulcerans_Agy99 DILINNAGTN-PAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGE
MLBr_01807|M.leprae_Br4923 EVLVANAGIT--SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
.: . *. *:
Mb2882c|M.bovis_AF2122/97 GK-GSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRV
Rv2857c|M.tuberculosis_H37Rv GK-GSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGIRV
TH_2488|M.thermoresistible__bu GR-GSIVNITSMVATK-AVPGASVYSSSKAAVESLTRSWAVEFAAHGIRV
Mvan_1212|M.vanbaalenii_PYR-1 GR-GAIVNVTSMVAWK-GVPGASVYSASKAAVESLTRTWAAEFAPH-VRV
MSMEG_1689|M.smegmatis_MC2_155 GR-GSIVNVTSMVASK-GVAGASTYSASKAAVESLTRTWAAEFGPRGVRV
MMAR_0629|M.marinum_M GR-GSIVNVTTMVAEF-GAAGTGLYGASKAAIALLTKSWAAEYGPSGVRV
MAB_0164|M.abscessus_ATCC_1997 EH-ASVLNVVSVAAFQ-YVPMLSMYAAMKATLMSFTRSMAAEYTARGIRV
Mflv_2424|M.gilvum_PYR-GCK EQTGSVINVTSIEGSR-AAPGYAAYAAAKAGVVNYTKTASFELAPYGIRV
MAV_3655|M.avium_104 HG-GSIVNTASIGGLH-QSPAMGMYNATKAALIHVTKQLALELSPR-VRV
MUL_2173|M.ulcerans_Agy99 HG-GVVINTASIGGMH-QSPAMGMYNATNAALIHVTKQLALELSPR-VRV
MLBr_01807|M.leprae_Br4923 RF-GRYIFMGSVVGLS-GVPGQANYAASKSGLIGMARSLARELGSRSITA
. : :. . . * : :. : :: . : : .
Mb2882c|M.bovis_AF2122/97 NALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLA
Rv2857c|M.tuberculosis_H37Rv NALCPGPVNTPLLQELFAKNPERAARRMVHVPLGRFAEPDEIAAAVAFLA
TH_2488|M.thermoresistible__bu NAVAPGPTSTDGV-ATEWG--ETNEALGRALPIGRTADPDEIAQAVVFLA
Mvan_1212|M.vanbaalenii_PYR-1 NSVAPGPTDTEGV-VAEWG--DTNDELGRALPLGRTATPGEIAQAVLFLA
MSMEG_1689|M.smegmatis_MC2_155 NSVAPGPTRTEGV-EAEWG--DTNEQLGKALPLGRTAQPEEIAHAVLFLC
MMAR_0629|M.marinum_M NAVSPGPTRTEG--TVEMG--EALDQLAAAAPAGRPADPTEIASTIVYLA
MAB_0164|M.abscessus_ATCC_1997 NALAPGTVDTYML-QQNPQ--EIIDAMAAQSFMGRVAHTDEMIGPALLLL
Mflv_2424|M.gilvum_PYR-GCK NGLAPDLTMTEGLQKLAFG--ELSGTVARMVPMRRAGHVDEMASAAVFLA
MAV_3655|M.avium_104 NAIAPGVVRTRLA-EALWK--DHEDPLSSSIALGRIGEPIDVAAAVAFLV
MUL_2173|M.ulcerans_Agy99 NAICPGVVRTKLA-EALWK--DHEDPLAANIALGRIGEPVDVAEAVGFLV
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMTRAMDSK---YQEAALQAIPLGRIGAVEEIAGAVSFLA
* :.*. * * . :: . *
Mb2882c|M.bovis_AF2122/97 SDDASFITASTFLVDGGISSAYVTPL------------
Rv2857c|M.tuberculosis_H37Rv SDDASFITASTFLVDGGISSAYVTPL------------
TH_2488|M.thermoresistible__bu SSRASFITGAVLHVDGGGIAV-----------------
Mvan_1212|M.vanbaalenii_PYR-1 SPRAGFVTGSVLHADGGGTAI-----------------
MSMEG_1689|M.smegmatis_MC2_155 SPRASFITGSTLHADGGGAAV-----------------
MMAR_0629|M.marinum_M SDAASFIHGAVVPVDGGRAAV-----------------
MAB_0164|M.abscessus_ATCC_1997 SDAGSFITGQVIVADGGGGVQR----------------
Mflv_2424|M.gilvum_PYR-GCK SDMASYITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA
MAV_3655|M.avium_104 SDAASWITGETLVIDGGTVLGAAQGFRSAPTPS-----
MUL_2173|M.ulcerans_Agy99 SDAASWITGETMVIDGGLLLGSAAGFQSRPGSAS----
MLBr_01807|M.leprae_Br4923 SEDAGYISGAVIPVDGGLGMGH----------------
* ..:: . .. ***