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SAVRTSPDITMALTVDGIRAAIQPALERLSATARFREDTRDYAYDDVYELAAHGVGLTGIARTEGGAGGT VRDVADLTITIARADSNVAQALRPTFLVAHQIAARHDVPLRAVNLERLRNRALFAGTGNERNGGASGSVS TTARRVEGGYVINGRKYYSTGGLYASYFSAQALTEDGTVVHFTVPVDRPGVDRLDDFDAIGQRLTQSGST QLTEVRVDDDETVVMADSIPDNPWRGSFAQLYLAAVQAGIAARALDDAVQYVREKGRPIKHSSATRSVDD PYIRQTVGEIAARAQGARAAVLLAAEALQNQRGLRREQARHAGAEAAVTVAQAGVVAVESALRAAELLFD VGGGSITDRSLGFDRHWRNARTAANHNPRQWKLAVAGAYHLVGEEPPTTGLF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4094 | - | - | 100% (403) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4391 | - | 2e-51 | 34.54% (388) | acyl-CoA dehydrogenase-family protein |
| M. smegmatis MC2 155 | MSMEG_5001 | - | 3e-51 | 34.20% (386) | pesticide degrading monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | 8e-09 | 26.64% (244) | hypothetical protein Mb3121c |
| M. gilvum PYR-GCK | Mflv_4370 | - | 1e-11 | 23.42% (380) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3094c | - | 8e-09 | 26.64% (244) | hypothetical protein Rv3094c |
| M. leprae Br4923 | MLBr_00660 | fadE23 | 1e-06 | 25.52% (239) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1422c | - | 4e-52 | 35.51% (383) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_4034 | fadE | 1e-10 | 23.87% (377) | acyl-CoA dehydrogenase FadE |
| M. avium 104 | MAV_3422 | - | 2e-52 | 35.99% (389) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_3393 | - | 5e-44 | 33.66% (407) | PUTATIVE Acyl-CoA dehydrogenase, type 2, C-terminal domain |
| M. ulcerans Agy99 | MUL_3778 | fadE19 | 3e-07 | 22.93% (362) | acyl-CoA dehydrogenase FadE19 |
| M. vanbaalenii PYR-1 | Mvan_3173 | - | 3e-42 | 32.03% (409) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3121c|M.bovis_AF2122/97 --------------------MNQSETEIEILAEKIARWARARSAEIERDR
Rv3094c|M.tuberculosis_H37Rv --------------------MNQSETEIEILAEKIARWARARSAEIERDR
MAB_1422c|M.abscessus_ATCC_199 -MTSAPSV--------LEIRALPGTDTYRNLLAQVAEGARD--RDLD--D
MAV_3422|M.avium_104 -MPVAFHR--------QDT--PAGAAAVQPVLAEIAADYRL--RLADGGT
MSMEG_4094|M.smegmatis_MC2_155 -MSAVRTS--------PDITMALTVDGIRAAIQPALERLSATARFREDTR
TH_3393|M.thermoresistible__bu ----VTEP--------LTMARIVDTAEALAVAARLSGSFAAEASTRDAER
Mvan_3173|M.vanbaalenii_PYR-1 MATDITDR--------IPDTLLRTPADALAAAEEVAEAIAAGSAERERAG
Mflv_4370|M.gilvum_PYR-GCK -MASPPANAAEAGIPSAEVNDEDFQAILAATREFVRTAVVPREQEILSTD
MMAR_4034|M.marinum_M -MTAP------------QVSDEDFAQILAQTRHFVRSVVLPREQQILDED
MUL_3778|M.ulcerans_Agy99 -MTTAIS---------AGTLPKEYQDLRDTVADFARSVVAPVSAKHDEEH
MLBr_00660|M.leprae_Br4923 -MAINLELS---------RKLQAVIVKTHQGAAELMRPIARKYDLKEHTY
Mb3121c|M.bovis_AF2122/97 RLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGW
Rv3094c|M.tuberculosis_H37Rv RLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAGW
MAB_1422c|M.abscessus_ATCC_199 ENPFDQVRLLKEAGFGRLRIPTELGGAGLSVRQLFSAIIDVAQADPIVAH
MAV_3422|M.avium_104 EPPLRGLKLVRDHRLGALRLARELGGAGYTAPEFFDYLVALAAADPDLAH
MSMEG_4094|M.smegmatis_MC2_155 DYAYDDVYELAAHGVGLTGIARTEGGAGGTVRDVADLTITIARADSNVAQ
TH_3393|M.thermoresistible__bu LLPYEQVCELKRSGLLTLSVPAEHGGLDVPATVLAEVFRLLAHGDPSVAQ
Mvan_3173|M.vanbaalenii_PYR-1 AVLTPQLRLVAESGLLGISVPTAHGGPGLPASTVVEVLRRLARADGAVGQ
Mflv_4370|M.gilvum_PYR-GCK QVPDDLREQTKSMGLFGYAIPQEWGGLGLNLAQDVELAMELGYTSLALRS
MMAR_4034|M.marinum_M RVPEDLRDQAKQMGLFGYAIPPQWGGLGLNLVQDVELAMELGYTSLAVRS
MUL_3778|M.ulcerans_Agy99 SFPYEVVAKMGEMGLFGLPFPEEYGGMGGDYFALALALEELGKVNQSVAI
MLBr_00660|M.leprae_Br4923 PVELDTLFNLFAGAAESFAFAGADALGDEDNKDENHNGANMAALLQTLEA
.. . :.
Mb3121c|M.bovis_AF2122/97 CVSIAITSALLVAY-LPARSR--EEMFGG---GRGVAAG-VWAPRGTARS
Rv3094c|M.tuberculosis_H37Rv CVSIAITSALLVAY-LPARSR--EEMFGG---GRGVAAG-VWAPRGTARS
MAB_1422c|M.abscessus_ATCC_199 IFRTHFWFVEERLR-TLADPV--SAAWLTKVNEGNLFAN-AFSEKGSLAV
MAV_3422|M.avium_104 ILRIHYALVEELQV-TPRRPG--SDRWIAVVAEGGLIGG-ANAEQSQKSV
MSMEG_4094|M.smegmatis_MC2_155 ALRPTFLVAHQIAA-RHDVPL--RAVNLERLRNRALFAG-TGNERNGGAS
TH_3393|M.thermoresistible__bu IPHSHFTFLEVLRL-QGTERQ--RGFFYGLVLEGALFAN-AQSERG-PHP
Mvan_3173|M.vanbaalenii_PYR-1 LLLSHFVVAQAISG-LGHTQP--APRIYADLLAGAQLGN-ASAERGTAHA
Mflv_4370|M.gilvum_PYR-GCK MFGTNNGIAGQVLVGYGTDEQ--KKTWLERIASGEIVASFALTEPGAGSN
MMAR_4034|M.marinum_M MFGTNNGIAGQVLVGFGTDEQ--KARWLEPIASGDVVASFALTEPGAGSS
MUL_3778|M.ulcerans_Agy99 TLEAGVGLGAMPIYRFGNEEQ--KSKWLPDLLAGRALAGFGLTEPGAGSD
MLBr_00660|M.leprae_Br4923 CWGDVAMLLSIPYQGLGNAAISAVATNKQLERLGKVWAAMAITEPGFGSD
. .
Mb3121c|M.bovis_AF2122/97 VDG--------------GVVVSGRWPFCSG--INHADIMFAGCFVDDR--
Rv3094c|M.tuberculosis_H37Rv VDG--------------GVVVSGRWPFCSG--INHADIMFAGCFVDDR--
MAB_1422c|M.abscessus_ATCC_199 GSLVFNTRLLPVGD---AYRLNGEKFYSTG--TLFADYLTVTATTDRD--
MAV_3422|M.avium_104 GGNHRDTRLVTTPD---GLRLRGRKFYSTG--AQFSDYLRITAQDDDG--
MSMEG_4094|M.smegmatis_MC2_155 GSVSTTARRVEG-----GYVINGRKYYSTG--GLYASYFSAQALTEDG--
TH_3393|M.thermoresistible__bu IDVDTTVLLRRGAG---DYLLTGRKFYSTG--ALFADWIVVRASVPADAA
Mvan_3173|M.vanbaalenii_PYR-1 LDRRTTVTRRD--G---HWVLNGTKYYATG--TLGATWIAVAARIEGREN
Mflv_4370|M.gilvum_PYR-GCK PSGLRTKAVRDGDGPHSGWILNGQKRFITN--APNADLFVTFARSRPADD
MMAR_4034|M.marinum_M PAGLRTKAVRDGDD----WLITGQKRFITN--APVADLFVVFARTRPASD
MUL_3778|M.ulcerans_Agy99 AGSTRTTARLDGGE----WVVNGSKQFITNSGTDITSLVTITAVTGSIAD
MLBr_00660|M.leprae_Br4923 SAAVSTTATLDGDE----YVINGEKIFVTAG--SRATHIVVWATLDKSLG
: * : : : . .
Mb3121c|M.bovis_AF2122/97 ---------QVPSVVALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPA
Rv3094c|M.tuberculosis_H37Rv ---------QVPSVVALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPA
MAB_1422c|M.abscessus_ATCC_199 --------SVASVIVPGDRDGVRLVDDWDGFGQRRTGTGTTIFSQVDVAA
MAV_3422|M.avium_104 --------APTAVVIPVDRAGVEHLDDWDGIGQRQTGSGTTVFNDVAVAD
MSMEG_4094|M.smegmatis_MC2_155 --------TVVHFTVPVDRPGVDRLDDFDAIGQRLTQSGSTQLTEVRVDD
TH_3393|M.thermoresistible__bu DAPTAATPKAVAFVPRHAPGLTV-IDDWDGMGQRTTASGSVTLDEVRVPA
Mvan_3173|M.vanbaalenii_PYR-1 GD------TATAFVRPDQEGVTLDLESWSAFGQRGTASGEVRLNNVVVDD
Mflv_4370|M.gilvum_PYR-GCK KGA-----GIAVFLVPADTPGVDIGAKDKKMGQEGAWTADVNFTDVEVPD
MMAR_4034|M.marinum_M KSP-----GIAVFLVPAQSAGVEVGAKDAKMGQEGAWTADVSFTDVRVDD
MUL_3778|M.ulcerans_Agy99 GKK-----EISTIIVPSGTPGFIVEPVYNKVGWNASDTHPLSFDDARVPE
MLBr_00660|M.leprae_Br4923 ------HAAIKSFIVPREHPGVTVERLEYKLGIRGSDTAAIRFDNVRIPK
.* . : : :. :
Mb3121c|M.bovis_AF2122/97 DRVFSVF--DGPIVDR-PLYRFPVFGFFALSIGAAALGNARAAIDDLVEL
Rv3094c|M.tuberculosis_H37Rv DRVFSVF--DGPIVDR-PLYRFPVFGFFALSIGAAALGNARAAIDDLVEL
MAB_1422c|M.abscessus_ATCC_199 DEILSETPYDAAPV---PTTQYASLQLYILAIVAGVLRAVVDDGEALLRS
MAV_3422|M.avium_104 DEVFPLG--STIGV---NRARGALVQLYLHAVAAGILRSLTEDAAALVRG
MSMEG_4094|M.smegmatis_MC2_155 DETVVMA--DSIPD---NPWRGSFAQLYLAAVQAGIAARALDDAVQYVRE
TH_3393|M.thermoresistible__bu DHVV----PFTPIFRR-PTVYGARAQLWHAALDVGIATAALEEG-VRLAA
Mvan_3173|M.vanbaalenii_PYR-1 DLLIDEGPPPDPITAD-PSVLGAFDQALHAAIDIGIARAALEDGAVFVRT
Mflv_4370|M.gilvum_PYR-GCK TALVGGSEDLGYRA---AMTSLARGRVHIAALAVGAAQRALDESVAYAAT
MMAR_4034|M.marinum_M AALVGGSEDIGYRA---AMTSLARGRVHIAAIAVGAAQRALDESVAYAST
MUL_3778|M.ulcerans_Agy99 ENLLG-IRGKGYAN---FLSILDEGRIAIAALATGVAQGCVDESVKYAKE
MLBr_00660|M.leprae_Br4923 DNLLGNPEIEVGKGFSGVMETFDNTRPIVAAMAVGVGRAALEEIRKILTD
. :: .
Mb3121c|M.bovis_AF2122/97 AGGK---------KGLGSTRTLAERSATQAAAATAESALGAARALFYEVI
Rv3094c|M.tuberculosis_H37Rv AGGK---------KGLGSTRTLAERSATQAAAATAESALGAARALFYEVI
MAB_1422c|M.abscessus_ATCC_199 RQRN---FSHALTERPVDDPLLQRTLGELSATAFAAEATVLAAADAIEAA
MAV_3422|M.avium_104 RRRT---YTFASADTPTADPQLLQIVGEIDAVAYTAHALVRNAAAELAPA
MSMEG_4094|M.smegmatis_MC2_155 KGRP---IKHSSATRSVDDPYIRQTVGEIAARAQGARAAVLLAAEALQNQ
TH_3393|M.thermoresistible__bu RARP---HFESGAPVATDDPTLIQSAGEVAVTVRAAQALLGEAARAVD--
Mvan_3173|M.vanbaalenii_PYR-1 RSRPWKEALDAGIERADQEPHVVRRFGELTARLYALEALLARGTALID--
Mflv_4370|M.gilvum_PYR-GCK ATQG--------GTPIGDFQLVQAMLADQQTGVMAGRALVRDAARLWVT-
MMAR_4034|M.marinum_M ATQG--------GVTIGSFQLVQAMLADQQTGVLAGRALVRDAARMWVS-
MUL_3778|M.ulcerans_Agy99 RQSF--------GQPIGSYQAISFKIARMEARAHVARTAYYEAAAKMLA-
MLBr_00660|M.leprae_Br4923 AGIE-----ICYDKPSHSQNAAAAEFLRMEADWEASYLLSLRAAWQADN-
. :
Mb3121c|M.bovis_AF2122/97 EAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYD
Rv3094c|M.tuberculosis_H37Rv EAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYD
MAB_1422c|M.abscessus_ATCC_199 TATLRDGVPDAQLAQEAQVAVAKAKVHIDAVALDAATKLLDLGGASAASR
MAV_3422|M.avium_104 LQAARDTGIDPELEAAASIAAARVKVAIQEPALRAASRVFDAGGASAVQA
MSMEG_4094|M.smegmatis_MC2_155 RGLRRE--QARHAGAEAAVTVAQAGVVAVESALRAAELLFDVGGGSITDR
TH_3393|M.thermoresistible__bu -AATAD--LTEDTAAAASIAVATAKVAAERAALRASTALFELGGTRSATV
Mvan_3173|M.vanbaalenii_PYR-1 -EAYAAPEVTRDAAAQASLTVAAAKALAQQDAVEIAGAIFELTGTSGTDG
Mflv_4370|M.gilvum_PYR-GCK -------------GQDRRIAPSAAKLFCTEMAGKVADLAVQIHGGSGYMR
MMAR_4034|M.marinum_M -------------GADRRIAPSAAKLFCTEMAGKVADLAVQIHGGSGYMR
MUL_3778|M.ulcerans_Agy99 -------------GKPFKKEAAIAKMISSEAAMDNARDAAQVHGGYGFMN
MLBr_00660|M.leprae_Br4923 -------------NIPNSKEASMSKAKAGRMASDVTLKAVELAGTAGYSE
: : *
Mb3121c|M.bovis_AF2122/97 NAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML--
Rv3094c|M.tuberculosis_H37Rv NAPLQRRFRDAFTATAHFQVNEASRELPGRVLLDQPADVSML--
MAB_1422c|M.abscessus_ATCC_199 TRNLDRHWRNIRTISLHNPVHYKARVIGQNLLHGTPLPANAYF-
MAV_3422|M.avium_104 SALLDRHWRNLRTLFSHNPTVYKARVLGDVVVNGAALPDTSFF-
MSMEG_4094|M.smegmatis_MC2_155 SLGFDRHWRNARTAANHNPRQWKLAVAGAYHLVGEEPPTTGLF-
TH_3393|M.thermoresistible__bu SANLSRFWRDARTHTLHDPTRWKLHHIGRYLLSGTRPPRHGQL-
Mvan_3173|M.vanbaalenii_PYR-1 AVNLDRHWRNVRVHSLHDPARWKYVHLGNHTLHDTRPPRLGLIL
Mflv_4370|M.gilvum_PYR-GCK EVPVERIYRDVRLLRLYEGTSEIQKLIIGGGLVKGAKGK-----
MMAR_4034|M.marinum_M GVPVERIYRDVRLLRLYEGTSEIQQLIIGSNLIKAANR------
MUL_3778|M.ulcerans_Agy99 EYPVARHYRDSKILEIGEGTTEVQLMLIARSLGLS---------
MLBr_00660|M.leprae_Br4923 KALLEKWARDSKILDIFEGTQQIQQLVVARRLLGLSSSELK---
. : *: :