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VNQSETEIEILAEKIARWARARSAEIERDRRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEA VARGDASAGWCVSIAITSALLVAYLPARSREEMFGGGRGVAAGVWAPRGTARSVDGGVVVSGRWPFCSGI NHADIMFAGCFVDDRQVPSVVALNKDELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPIVDR PLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTLAERSATQAAAATAESALGAARALF YEVIEAAWQVSHDAEAVPVTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAFTATA HFQVNEASRELPGRVLLDQPADVSML
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3121c | - | - | 100% (376) | hypothetical protein Mb3121c |
| M. bovis AF2122 / 97 | Mb3601c | - | 2e-28 | 28.12% (345) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb1706 | fadE16 | 7e-12 | 23.16% (380) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3440 | - | 4e-37 | 33.52% (352) | acyl-CoA dehydrogenase type 2 |
| M. tuberculosis H37Rv | Rv3094c | - | 0.0 | 100.00% (376) | hypothetical protein Rv3094c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0075 | - | 2e-37 | 29.94% (354) | putative hydroxylase |
| M. marinum M | MMAR_1556 | - | 1e-179 | 83.24% (376) | dehydrogenase |
| M. avium 104 | MAV_2166 | - | 2e-40 | 30.08% (369) | acyl-CoA dehydrogenase domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2077 | - | 6e-35 | 29.00% (369) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_2929 | - | 9e-36 | 28.65% (370) | PUTATIVE acyl-CoA dehydrogenase, C- domain protein |
| M. ulcerans Agy99 | MUL_3474 | - | 1e-176 | 80.83% (386) | dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3194 | - | 2e-35 | 31.55% (355) | acyl-CoA dehydrogenase type 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3440|M.gilvum_PYR-GCK --------------------------MTAVEQAHALRDVVGAHAAESEQL
Mvan_3194|M.vanbaalenii_PYR-1 ----------------------------MVERARGMRDLVRAQAAESEQI
Mb3121c|M.bovis_AF2122/97 -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
Rv3094c|M.tuberculosis_H37Rv -----------MNQ----------SETEIEILAEKIARWARARSAEIERD
MMAR_1556|M.marinum_M -----------MNQPDLSAAPLRRADSEMENLAEKIALTAREMSAEIDRD
MUL_3474|M.ulcerans_Agy99 MTEPPSLPGVLMNQPDLSAAPLRRADSEMEDLAEKIALTAREMSAEIDRD
MSMEG_2077|M.smegmatis_MC2_155 ----------------MTISVSGAAAATTSAITDEFVTRLAERAREAEEL
TH_2929|M.thermoresistible__bu ---------------------MSATAAQTAEITAEFVQRLAERAAEADEL
MAV_2166|M.avium_104 ----------------------MVEHHPLHGITDEFVARLGERAEEAERL
MAB_0075|M.abscessus_ATCC_1997 ------------MEGQRGGRTIVAMTERVIDRINDLAEQLREQAWEAEKL
: : * :.
Mflv_3440|M.gilvum_PYR-GCK RTLAPAVVDAMWSSGLMSAFNPSAAGGSEPTFAEMIETWIEMAWQDGSFG
Mvan_3194|M.vanbaalenii_PYR-1 RTMTPAIVEAMWSTGLMSAFNPAPAGGVEPSFAEMIETWIEMAWQDGSFG
Mb3121c|M.bovis_AF2122/97 RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
Rv3094c|M.tuberculosis_H37Rv RRLPDELVTRLREAGLLRATMPREVAAPELAPGRALRCAEAVARGDASAG
MMAR_1556|M.marinum_M RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
MUL_3474|M.ulcerans_Agy99 RRLPDELVARLGEAGLLRATMPREVQAAELAPGPALRCAEAVARGDASAG
MSMEG_2077|M.smegmatis_MC2_155 RRLPDATMTDLAASGFTELLTPARFGGQQADFPALLDPVRRMAHGCASSA
TH_2929|M.thermoresistible__bu RRLPAATIDDLTASGFTELLVPARYGGRQAEFPALLDPVRRMAHGCTSSA
MAV_2166|M.avium_104 RRLPAATVDEFRQTELFRLLLPARFGGLEASFPELLQPIRRMAQGCASSA
MAB_0075|M.abscessus_ATCC_1997 GRLPDETAKMLKAAGLIRLLQPQKYGGYEAHPREFAETVMTTAALDPASG
:. : : : * . : * : .
Mflv_3440|M.gilvum_PYR-GCK WVGIANFPSSFAAASYLPDSGFAEVFTANDNRVTMGGQFFPNGQGVAVDG
Mvan_3194|M.vanbaalenii_PYR-1 WVGIANLPSSFAAATYLPDGGFAEVFTANHNRVTMGGQFFPNGQGHAVDG
Mb3121c|M.bovis_AF2122/97 WCVSIAITSALLVA-YLPARSREEMFGGG--RGVAAGVWAPRGTARSVDG
Rv3094c|M.tuberculosis_H37Rv WCVSIAITSALLVA-YLPARSREEMFGGG--RGVAAGVWAPRGTARSVDG
MMAR_1556|M.marinum_M WCVSIAITSALLVA-YLPASSRDEMFGAG--RSVAAGVWAPRGKAKSVDG
MUL_3474|M.ulcerans_Agy99 WCVSIAITSALLVA-YLPASSRDEMFGAG--RSVAAGVWAPRGKAKSVDG
MSMEG_2077|M.smegmatis_MC2_155 WTIGFLALHNWMLA-LFGEQAQAEAYATR--PFLAPAPLAPNGRGLPTEG
TH_2929|M.thermoresistible__bu WTIGFFALHNWMLA-LFDEQAQQEVFADR--PVLAPAPLAPTGRGLPVDG
MAV_2166|M.avium_104 WTLGFYALHNWMLS-LFDPQAQREVFASG--PVLAPAPLAPTGRATPADG
MAB_0075|M.abscessus_ATCC_1997 WICGVVGVHPWQVA-FADSRVAEEMWGEDQ-DIWMASPYAPTGVAKPVDG
* : * : . * * . ..:*
Mflv_3440|M.gilvum_PYR-GCK GYRLTGAWSFGSGTGHAEYVAAGFFPMVDGEMRWAGEGIPDMQVAVVPRD
Mvan_3194|M.vanbaalenii_PYR-1 GYRLTGSWSFGSGTGHAEYVAAGFLPMVDGEIRWAGDGVPDMQVAVVPRA
Mb3121c|M.bovis_AF2122/97 GVVVSGRWPFCSGINHADIMFAGCF----------VDDRQVPSVVALNKD
Rv3094c|M.tuberculosis_H37Rv GVVVSGRWPFCSGINHADIMFAGCF----------VDDRQVPSVVALNKD
MMAR_1556|M.marinum_M GVVVSGRWPFCSGINHADMMFAGCF----------VEGQPVPSVVALPKD
MUL_3474|M.ulcerans_Agy99 GVVVSGRWPFCSGINHADMMFAGCF----------VEGQPVPSVVALPKD
MSMEG_2077|M.smegmatis_MC2_155 GVRLSGRWSWATGVMHANWIMVGALCG--------PDDAIYPALALLPAS
TH_2929|M.thermoresistible__bu GVRLTGRWSWATGVMHANWVLVGALCG--------PEDAIYPALALLPAA
MAV_2166|M.avium_104 GVRLTGRWSWATGAMDADWLIVGALIE--------RTDRIDPALVVVPAG
MAB_0075|M.abscessus_ATCC_1997 GYIFNGRWQFSSGTDHCDWIILGAMLG--DADGTPIMPPKMLHMILPRAD
* ..* * : :* ..: : * : :
Mflv_3440|M.gilvum_PYR-GCK QVSFKDGWHVQGLRGTGSYDYAIDDVFVPHDRTFALFTREPK------RG
Mvan_3194|M.vanbaalenii_PYR-1 EVSFKDGWHVQGLKGTGSYDYSIDDVFVPHDRTFALFTREPR------RG
Mb3121c|M.bovis_AF2122/97 ELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPI--------V
Rv3094c|M.tuberculosis_H37Rv ELQVLDTWHTLGLRGTGSHDCVADDVFVPADRVFSVFDGPI--------V
MMAR_1556|M.marinum_M DLRALDTWHTLGLRGTGSHDCVAEEVFVPADRVFSVFDGPS--------I
MUL_3474|M.ulcerans_Agy99 DLRALDTWHTLGLCGTGSHDCVAEEVFVPADRVFSVFDGPT--------I
MSMEG_2077|M.smegmatis_MC2_155 DIEVVDVWHTDGMRATGSNDVVVTDAFVPEHRLVSVIDVYTGTAPGAKVH
TH_2929|M.thermoresistible__bu DVTVEDTWHTVGMRATGSADVVVTEAFVPEHRLLRVTDIYAGTTPGAALH
MAV_2166|M.avium_104 QVEVVDTWHTAGMRGTGSHDVVIADVFVPEHRLVAVADIYGGTAPGAREH
MAB_0075|M.abscessus_ATCC_1997 YQIVEDSWNVVGLRGTGSKDIIVNDAFVPSYRVMDGDQVIDGTAQRDAGM
* *:. *: .*** * :.*** * .
Mflv_3440|M.gilvum_PYR-GCK SSPAGRMGMMPVTAAGHAAWALGVAKSMLDDVAELAATKFRMSDMASLAS
Mvan_3194|M.vanbaalenii_PYR-1 SSPATRMGMMPVTAAGHAAWALGVAKSMLDDVSELAATKFRMSDMAALAS
Mb3121c|M.bovis_AF2122/97 DRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTLAE
Rv3094c|M.tuberculosis_H37Rv DRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGGKKGLGSTRTLAE
MMAR_1556|M.marinum_M DRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKRTLAE
MUL_3474|M.ulcerans_Agy99 DRPLYRFPVFGFFALSIGAAALGNARAAIDDLVELAGDKKGLGAKRTLAE
MSMEG_2077|M.smegmatis_MC2_155 DAATYRWPMVPALALLAAMPALGSAERAVEIYAQRLSERVIAYEGVKQKD
TH_2929|M.thermoresistible__bu DAAAYRWPMVPALALLAAMPALGSAERVTDLFAERLGHRVIAYEGVAQRD
MAV_2166|M.avium_104 AAATYRWPMVPALALTAAMPVLGAAERVVQLFADRLGERVLAYSAVAQKD
MAB_0075|M.abscessus_ATCC_1997 TDTLYRMPWSTMFPLGISSAVIGIAEGALAAHLEYQRER-VGAQGTAVKD
. * . . .:* *. : : .
Mflv_3440|M.gilvum_PYR-GCK RPTFQKDLAHHVAAWRAARLLVLDAFTGAEGAVAAGA----------ELT
Mvan_3194|M.vanbaalenii_PYR-1 RPTFQKGLAHHVAAWRAARLLVLDAFGTAEAAVAGGD----------DLT
Mb3121c|M.bovis_AF2122/97 RSATQAAAATAESALGAARALFYEVIEAAWQVSHDAE----------AVP
Rv3094c|M.tuberculosis_H37Rv RSATQAAAATAESALGAARALFYEVIEAAWQVSHDAE----------AVP
MMAR_1556|M.marinum_M RSATQTAVATAEAALGAARALFYEAIDSAWQASHNPD----------PVP
MUL_3474|M.ulcerans_Agy99 RSATQTAVATAEAALGAARALFYEAIDSAWQASHNPDPVPVPVPVPVPVP
MSMEG_2077|M.smegmatis_MC2_155 KPAAVAHLGEARVRLRALRGLLADTVGEIEDTVTAGD----------PVS
TH_2929|M.thermoresistible__bu KPIAQAHLGRARVRLRALHGLLADTVGQIQQLVAAGD----------PVP
MAV_2166|M.avium_104 QPAAQIRLGEARVRLDALRALVAQTADRIEAIVAGGD----------RVS
MAB_0075|M.abscessus_ATCC_1997 DPYVLFAIGEAAADINAARQEILANVDKIWGIVDSGK----------EVS
. . * : . :.
Mflv_3440|M.gilvum_PYR-GCK PTMRADMRVAAVFATDTARGCAEWAHLAAGTTSIREGSRLERAFRDIYTG
Mvan_3194|M.vanbaalenii_PYR-1 PTLRADMRVAAVFATDTARACAEWAHLVAGTSSIREGSRLERAFRDVYTG
Mb3121c|M.bovis_AF2122/97 VTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAFTA
Rv3094c|M.tuberculosis_H37Rv VTMRNRLRLAATHAVRTSADVVRSMYDLAGGTAIYDNAPLQRRFRDAFTA
MMAR_1556|M.marinum_M VALRNRLRLAATHAARTSADVVRIMYDLAGSSAIYDGSPLQRRFRDAFTA
MUL_3474|M.ulcerans_Agy99 VALRNRLRLAATHAARTSADVVRTMYDLAGSSAIYDGSPLQRRFRDAFTA
MSMEG_2077|M.smegmatis_MC2_155 REVRAQARLAAAHIVRESRAVIALLLASSGASAHFLDNPLQRISRDVGVL
TH_2929|M.thermoresistible__bu RPVRADARLAAAHIVHESRAIIGDLLAASGASVQFLSHPMQRFQRDVDVL
MAV_2166|M.avium_104 RSVRAEARLAAARTVHESRAIIADVTEASGASAHFLSSPMQRAKRDVDIA
MAB_0075|M.abscessus_ATCC_1997 FADRAAGRRTQVRAAWRAVMAVDQIFSRSGGNAMRLDKPLQRYWRDAHTG
* * : . . : :* . . ::* **
Mflv_3440|M.gilvum_PYR-GCK TQHAFIS-EKVAIDAAQVWLGVVEDQFGL---
Mvan_3194|M.vanbaalenii_PYR-1 TQHAFIS-EKVAIDAAQVWLGVVEDQFGL---
Mb3121c|M.bovis_AF2122/97 TAHFQVN-EASRELPGRVLLDQPADVSML---
Rv3094c|M.tuberculosis_H37Rv TAHFQVN-EASRELPGRVLLDQPADVSML---
MMAR_1556|M.marinum_M TAHFQVN-EASRELPGRVLLGQHCDTSML---
MUL_3474|M.ulcerans_Agy99 TAHFQVN-EASRELPGRVLLGQHCDTSML---
MSMEG_2077|M.smegmatis_MC2_155 SGHVIFDHDTSCELAGALSIGMKISPIAMI--
TH_2929|M.thermoresistible__bu AGHVVFDYDTSRELAGALELGLKVSPLAMI--
MAV_2166|M.avium_104 AGHVVFDYDTSRELAGALAIGAKISPISMI--
MAB_0075|M.abscessus_ATCC_1997 LAHAIHVPSTVFHASALSSLGIEPQGPLRSMI
* . .. :. .