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MAGRPVDHQRRAELLDAIVDYAVEHGFSELTWRPVAAALGVTSNTLVHHFGTKEQMFQAVLERLRARLLV ATDELLGSRTDLASAARLAWELSSDPKRGPEFRLFFAVYGRALQAPEQFTNFLQRVVADWMGSLCKAQGP EVEPAAARQRATLVIATIRGLLLDLLATDDQDRVRDAAEAFLTSL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4070 | - | - | 100% (185) | transcriptional regulator, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_2406 | - | 7e-23 | 35.80% (176) | transcriptional regulator, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_5190 | - | 6e-08 | 28.41% (176) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 1e-05 | 38.71% (62) | hypothetical protein Mb2184c |
| M. gilvum PYR-GCK | Mflv_2461 | - | 5e-09 | 35.23% (176) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 3e-05 | 27.22% (158) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 6e-06 | 29.00% (100) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2952c | - | 2e-08 | 26.74% (187) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0108 | - | 7e-25 | 36.67% (180) | transcriptional regulatory protein |
| M. avium 104 | MAV_3916 | - | 3e-22 | 36.26% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1623 | - | 3e-07 | 28.57% (98) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1881 | - | 5e-24 | 37.08% (178) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4193 | - | 4e-07 | 34.43% (122) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3916|M.avium_104 -----------------------------MA-RTPDRQRRR-ELLDGLIA
MUL_1881|M.ulcerans_Agy99 -----------------------------MA-RTPDLQRRR-QLLDALVE
MSMEG_4070|M.smegmatis_MC2_155 -----------------------------MAGRPVDHQRRA-ELLDAIVD
MMAR_0108|M.marinum_M -------------------MISTSGTERRADGRQLRYQHRRGEIFDAVMA
Mflv_2461|M.gilvum_PYR-GCK MYLRYKNKYFFRGRLPATDGAGNNGGVAERWTRQRRVDHTRALLLDAAEE
Mvan_4193|M.vanbaalenii_PYR-1 --------------------------MAERWTRQRRVEHTRTLLLDAAEE
Rv2506|M.tuberculosis_H37Rv --------------MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAER
MAB_2952c|M.abscessus_ATCC_199 --MYARKNAKVIALGGWSVVVANLEGRASRRTQAQRSAEMRTRLLDATVE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mb2184c|M.bovis_AF2122/97 ------------------------------MPSADVGRQTRAQILRAAMD
TH_1623|M.thermoresistible__bu ----------------VRSRSNEETMASSTRRVGAETSKTRDTLLNCVEQ
::
MAV_3916|M.avium_104 EFAAGGIGDRSLRRVAEAVGTSHRMLLHHFGSREGLLLAIVEEVERRQMR
MUL_1881|M.ulcerans_Agy99 DFATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQMS
MSMEG_4070|M.smegmatis_MC2_155 YAVEHGFSELTWRPVAAALGVTSNTLVHHFGTKEQMFQAVLERLRARLLV
MMAR_0108|M.marinum_M HVLEHGITGLSFRTLAAAVGVSHVTLRHHFGTKDQLLVEILGAIGTR-IV
Mflv_2461|M.gilvum_PYR-GCK VVARQGFGAAALEVIADAAGYTRGAIYAHFGTKEELFLAVMERQLQRFLD
Mvan_4193|M.vanbaalenii_PYR-1 VVARLGFGAAALEVIADAAGYTRGAIYSHFGTKEELFLAVMERQLQRFLD
Rv2506|M.tuberculosis_H37Rv LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
MAB_2952c|M.abscessus_ATCC_199 CLVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQRTQ
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
Mb2184c|M.bovis_AF2122/97 IASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEA
TH_1623|M.thermoresistible__bu MMLAEGYASVTYRALAAKAGVTPSLVQYYFPTLDDIFIAAIRRYSERNIA
* :. * : :* : :
MAV_3916|M.avium_104 VLTELP-------REPAEGFAAMWADL-----RRPELREFERLFFECYSR
MUL_1881|M.ulcerans_Agy99 LLPELP-------TSPAESFTAMWADV-----RRPELRQLERLFFECYSR
MSMEG_4070|M.smegmatis_MC2_155 ATDELLG----SRTDLASAARLAWELS-----SDPKRGPEFRLFFAVYGR
MMAR_0108|M.marinum_M IPEQLG----------ADDVEALWRRW-----NEPGAQRRSQLLFEAYAQ
Mflv_2461|M.gilvum_PYR-GCK GFTDIVESFRSLEEMDVDRLAGRWRELTIGNPDRAALGYEFTLFLVRNPE
Mvan_4193|M.vanbaalenii_PYR-1 GFTDIVESFQSLEELDVDKLAGRWRELTIGNPDRAALGYEFTLFLVRNPE
Rv2506|M.tuberculosis_H37Rv GARDVTTR----SANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPA
MAB_2952c|M.abscessus_ATCC_199 AAIREIARLQGNPDPVSAVLDFMWEIH-----QGPIFVATMELWIAS--R
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEH---DGQGYRLIFENDNITEPR
Mb2184c|M.bovis_AF2122/97 EVVAPAMAAPPGVDRVRALMHAWVGYLERDVFPGGCFFAAAAADVDSQPG
TH_1623|M.thermoresistible__bu QLNKVLAER--ADDPLRALWEYSWDEATG--ALMTEFMALGNHRKNIRSE
MAV_3916|M.avium_104 AAQGEKPFARMLPDAVDDWLRQAETHAGAPFDPAMAR-----LGLAVIRG
MUL_1881|M.ulcerans_Agy99 AAQGEKRFAQMVPHAVYGWLAEASAVTEGSADPALVR-----LGLAVIRG
MSMEG_4070|M.smegmatis_MC2_155 ALQAPEQFTNFLQRVVADWMGSLCKAQGPEVEPAAARQ-RATLVIATIRG
MMAR_0108|M.marinum_M AVRHPDEYRGFLDRIVTDWIETIRQHAVQAGCPSDEAENFATLLIAQLRG
Mflv_2461|M.gilvum_PYR-GCK ARVRVAEQRRRTADSLAEYISVHVEKIGGRLRIPAPT--LARILIATYEG
Mvan_4193|M.vanbaalenii_PYR-1 ARARVAAQRRQTADSLAGYITSHIEKIGGRMRVPAAT--LARVLIATNEG
Rv2506|M.tuberculosis_H37Rv VAER--QVRKAQRQYVEVWVGVLRELNPGLAEADARL--MAHAVFGLLNS
MAB_2952c|M.abscessus_ATCC_199 TDKVLAQQIQRMEPFVNSALAAAIVQLLPEHPAPAELAKIVYTAMDTLRG
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVG--LVGISVDCARY
Mb2184c|M.bovis_AF2122/97 PVRDRIAATG-RAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAME
TH_1623|M.thermoresistible__bu IASATRKVRKIQLDALSAKFGKDAR-LGAEFDLSLPALQLLLSGLPKLLN
MAV_3916|M.avium_104 LLLDLVATGDEAGVDAAARAFVNLLNAGA---------------------
MUL_1881|M.ulcerans_Agy99 LLLDLVATDDDAGVDAAARAFAQLLSR-----------------------
MSMEG_4070|M.smegmatis_MC2_155 LLLDLLATDDQDRVRDAAEAFLTSL-------------------------
MMAR_0108|M.marinum_M LQFDLLASNDRARVAAALGTVVDGVRAKRAEWDASR--------------
Mflv_2461|M.gilvum_PYR-GCK ITLGGHIDGEDLARPFLELVLADVQPAESPDSERWD--------------
Mvan_4193|M.vanbaalenii_PYR-1 VTLGSHVDGEDLFRPFLEMVLGNVEPAG----------------------
Rv2506|M.tuberculosis_H37Rv TPHSMKAADSKPARTVRARAVLRAMTVAALSAADRCL-------------
MAB_2952c|M.abscessus_ATCC_199 ILIASFVDGDVERARRRWARASAHLRAVAVAAFPSLG-------------
MLBr_00815|M.leprae_Br4923 WLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-----------------
Mb2184c|M.bovis_AF2122/97 ANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES-------------
TH_1623|M.thermoresistible__bu LEAGVGVKTAHHEMAAAFERYMDALQPTAGTAETKTGAKSTPQRKSAAHR
MAV_3916|M.avium_104 ------
MUL_1881|M.ulcerans_Agy99 ------
MSMEG_4070|M.smegmatis_MC2_155 ------
MMAR_0108|M.marinum_M ------
Mflv_2461|M.gilvum_PYR-GCK ------
Mvan_4193|M.vanbaalenii_PYR-1 ------
Rv2506|M.tuberculosis_H37Rv ------
MAB_2952c|M.abscessus_ATCC_199 ------
MLBr_00815|M.leprae_Br4923 ------
Mb2184c|M.bovis_AF2122/97 ------
TH_1623|M.thermoresistible__bu PKSPGH