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YARKNAKVIALGGWSVVVANLEGRASRRTQAQRSAEMRTRLLDATVECLVAHGYAGTTTPRIAEMAGVTR GAQAYHFQSKEDLVVAAIEHLAQQRTQAAIREIARLQGNPDPVSAVLDFMWEIHQGPIFVATMELWIASR TDKVLAQQIQRMEPFVNSALAAAIVQLLPEHPAPAELAKIVYTAMDTLRGILIASFVDGDVERARRRWAR ASAHLRAVAVAAFPSLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2952c | - | - | 100% (228) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2392 | - | 9e-42 | 45.15% (206) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_0377 | - | 2e-41 | 45.95% (185) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2936c | - | 3e-13 | 26.74% (172) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0925 | - | 1e-11 | 29.35% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2912c | - | 3e-13 | 26.74% (172) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 5e-07 | 29.55% (132) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1796 | - | 4e-12 | 30.40% (125) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4851 | - | 1e-16 | 30.56% (180) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6139 | - | 2e-12 | 31.20% (125) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_1623 | - | 3e-08 | 27.74% (137) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_2044 | - | 2e-12 | 30.40% (125) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2337 | - | 3e-70 | 65.84% (202) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2936c|M.bovis_AF2122/97 ---------------------------MARTQQQRREETVARLLQASIDT
Rv2912c|M.tuberculosis_H37Rv ---------------------------MARTQQQRREETVARLLQASIDT
MMAR_1796|M.marinum_M ---------------------------MARTQQQRREETVARLLQASIDT
MUL_2044|M.ulcerans_Agy99 ---------------------------MARTQQQRREETVARLLQASIDT
MSMEG_6139|M.smegmatis_MC2_155 ---------------------------MARTQQQRREETVARLLDASIQT
MAB_2952c|M.abscessus_ATCC_199 -MYARKNAKVIALGGWSVVVANLEGRASRRTQAQRSAEMRTRLLDATVEC
Mvan_2337|M.vanbaalenii_PYR-1 ---MRTGVERAATR--------------RRTQAERTAAMRTRLLDATVEC
Mflv_0925|M.gilvum_PYR-GCK --MARSPAARRPPG----------------GNQERAERTRRTVIDETVRY
MAV_4851|M.avium_104 MSIAAGQQPGRPAGP----------TRRTTAPRKRGDDTRARIIDETVRC
MLBr_02677|M.leprae_Br4923 ------------------------MESQRRTQEERSTATRDALTLARHRL
TH_1623|M.thermoresistible__bu -VRSRSNEETMAS--------------STRRVGAETSKTRDTLLNCVEQM
. :
Mb2936c|M.bovis_AF2122/97 IIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLET
Rv2912c|M.tuberculosis_H37Rv IIEVGYARASAAVITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLET
MMAR_1796|M.marinum_M IVEVGYARASAAIITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLDI
MUL_2044|M.ulcerans_Agy99 IVGVGYARASAAIITKRAGVSVGALFRHFETMGDFMAATAYEVLRRQLDI
MSMEG_6139|M.smegmatis_MC2_155 IIDVGYARASAAVIARRAQVSDGALFRHFPTMGDFMAATAHEVMRRQLEV
MAB_2952c|M.abscessus_ATCC_199 LVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQRTQA
Mvan_2337|M.vanbaalenii_PYR-1 LVTYGYAGTTTPRIVEIAGVTRGAQVHHFRSKEDLVVAAIEHLAEQRIQA
Mflv_0925|M.gilvum_PYR-GCK ILDEGFAAPSVRRITERAGLTWGVVQYHFGDLGGLLMAVVDQGIAELTGA
MAV_4851|M.avium_104 IIEEGFAAATAKHVAERAGVTWGVIQYHFGDRNGLLMAVVDDGVARLVES
MLBr_02677|M.leprae_Br4923 WRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQ
TH_1623|M.thermoresistible__bu MLAEGYASVTYRALAAKAGVTPSLVQYYFPTLDDIFIAAIRRYSERNIAQ
*:* :. * : . * :. .
Mb2936c|M.bovis_AF2122/97 FTKQVAEIPADR--PALPAALTILRDITAGSTNAVLYELMVAART-----
Rv2912c|M.tuberculosis_H37Rv FTKQVAEIPADR--PALPAALTILRDITAGSTNAVLYELMVAART-----
MMAR_1796|M.marinum_M FTKQVAEIPADR--PALEAALAILRDITAGATNAVLYELMIAART-----
MUL_2044|M.ulcerans_Agy99 FTKQVAEIPADR--PALEAALAILRDITAGATNAVLYELMIAART-----
MSMEG_6139|M.smegmatis_MC2_155 FTKRIAEIPAEE--PPLQAVLTILRDVTGNDTNTVMYELLIAART-----
MAB_2952c|M.abscessus_ATCC_199 AIREIARLQGNP--DPVSAVLDFMWEIHQGPIFVATMELWIASRT-----
Mvan_2337|M.vanbaalenii_PYR-1 AIRQNGRLLSSP--DPVPRVLDFLWESHQGDMFVATIELWVAART-----
Mflv_0925|M.gilvum_PYR-GCK LERLRTETANLPAEHRTEVVVDALWQAFSSPTSMAALEILISTRA-----
MAV_4851|M.avium_104 LS--SADVSELPLRQRVEVVIDTAWSCYSSPTSMAAFEILHATRG-----
MLBr_02677|M.leprae_Br4923 IASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAF
TH_1623|M.thermoresistible__bu LNKVLAERADDP----LRALWEYSWDEATGALMTEFMALGNHRKN-----
. . :
Mb2936c|M.bovis_AF2122/97 -------------------DEKLKETLQNVLGQYSAKIHDAARALPGAES
Rv2912c|M.tuberculosis_H37Rv -------------------DEKLKETLQNVLGQYSAKIHDAARALPGAES
MMAR_1796|M.marinum_M -------------------DDKLKETLQHVLGQYRAKIYDAARTLPGAEG
MUL_2044|M.ulcerans_Agy99 -------------------DDKLKETLQHVLGQYRAKIYDAARTLPGAEG
MSMEG_6139|M.smegmatis_MC2_155 -------------------DEKLRVTLQEVLTEYAANIYETARTIPGFEQ
MAB_2952c|M.abscessus_ATCC_199 -------------------DKVLAQQIQRMEPFVNSALAAAIVQLLPEHP
Mvan_2337|M.vanbaalenii_PYR-1 -------------------DDVLAREVARVEPMVNSTLVAAIDQLLPNTF
Mflv_0925|M.gilvum_PYR-GCK -------------------ARDSDVNAQLVDTMRQFTELGRHLGEDLDAP
MAV_4851|M.avium_104 -------------------ALGDSSRRHLLDMNAAIGQLGRLITTD---P
MLBr_02677|M.leprae_Br4923 RDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYESAMAIRRHHR
TH_1623|M.thermoresistible__bu ---------------IRSEIASATRKVRKIQLDALSAKFGKDARLGAEFD
:
Mb2936c|M.bovis_AF2122/97 FPEET----FPVIVALMTNVFDG---AAIVRGVLPQPELEEQRIPMLTAL
Rv2912c|M.tuberculosis_H37Rv FPEET----FPVIVALMTNVFDG---AAIVRGVLPQPELEEQRIPMLTAL
MMAR_1796|M.marinum_M FPEET----FPAIVAVLTNVFDG---AAIVGAVLPQPDIDEQRIPVLAAL
MUL_2044|M.ulcerans_Agy99 FPEGT----FPAIVAVLTNVFDG---AAIVGAVLPQPDIDEQRIPVLAAL
MSMEG_6139|M.smegmatis_MC2_155 FPQNESRHEAMAAVALLVNTFDG---AAIIRPVLPQPDLEDARIALLSSL
MAB_2952c|M.abscessus_ATCC_199 APAELAKIVYTAMDTLRGILIAS---FVDGDVERARRRWARASAHLRAVA
Mvan_2337|M.vanbaalenii_PYR-1 SHKRIRNAIFTAMDALRGILVVS---FVDRDLDLARRRWDRACVDLGSAL
Mflv_0925|M.gilvum_PYR-GCK QATEIGNLIW---ATLRGIVLAQ---MVS----PQPLDTSRDRRTLVDVL
MAV_4851|M.avium_104 ANAGVAEVIW---ATLRGVVLAQ---MVI----GTTVDWSLERRALIDMV
MLBr_02677|M.leprae_Br4923 LPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGEL
TH_1623|M.thermoresistible__bu LSLPALQLLLSGLPKLLNLEAGVGVKTAHHEMAAAFERYMDALQPTAGTA
.
Mb2936c|M.bovis_AF2122/97 LTAGL-------------------
Rv2912c|M.tuberculosis_H37Rv LTAGL-------------------
MMAR_1796|M.marinum_M LSAAVPDTAP--------------
MUL_2044|M.ulcerans_Agy99 LSAAVPDTAP--------------
MSMEG_6139|M.smegmatis_MC2_155 FSR---------------------
MAB_2952c|M.abscessus_ATCC_199 VAAFPSLG----------------
Mvan_2337|M.vanbaalenii_PYR-1 ADALKAAPSE--------------
Mflv_0925|M.gilvum_PYR-GCK NTYMRAKGR---------------
MAV_4851|M.avium_104 TRVLQ-------------------
MLBr_02677|M.leprae_Br4923 LPRAATSSLL--------------
TH_1623|M.thermoresistible__bu ETKTGAKSTPQRKSAAHRPKSPGH