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MARTPDRQRRRELLDGLIAEFAAGGIGDRSLRRVAEAVGTSHRMLLHHFGSREGLLLAIVEEVERRQMRV LTELPREPAEGFAAMWADLRRPELREFERLFFECYSRAAQGEKPFARMLPDAVDDWLRQAETHAGAPFDP AMARLGLAVIRGLLLDLVATGDEAGVDAAARAFVNLLNAGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3916 | - | - | 100% (181) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1363 | - | 7e-07 | 33.00% (100) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2626 | - | 2e-06 | 29.41% (119) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1510c | - | 3e-06 | 35.48% (62) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1253 | - | 1e-06 | 25.56% (180) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1474c | - | 3e-06 | 35.48% (62) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3199c | - | 4e-07 | 45.61% (57) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1645 | - | 1e-69 | 72.47% (178) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_4070 | - | 3e-22 | 36.26% (182) | transcriptional regulator, TetR family protein, putative |
| M. thermoresistible (build 8) | TH_4015 | - | 3e-06 | 34.25% (73) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1881 | - | 6e-70 | 72.47% (178) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3785 | - | 1e-06 | 25.00% (200) | hypothetical protein Mvan_3785 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1645|M.marinum_M ----------------------------MPVARTPDLQRRRQLLDALVED
MUL_1881|M.ulcerans_Agy99 ------------------------------MARTPDLQRRRQLLDALVED
MAV_3916|M.avium_104 ------------------------------MARTPDRQRRRELLDGLIAE
MSMEG_4070|M.smegmatis_MC2_155 -----------------------------MAGRPVDHQRRAELLDAIVDY
Mb1510c|M.bovis_AF2122/97 ---------------------------MPKVSEDHLAARRRQILDGARRC
Rv1474c|M.tuberculosis_H37Rv ---------------------------MPKVSEDHLAARRRQILDGARRC
MAB_3199c|M.abscessus_ATCC_199 -------------------------MTRAGTKGMPRAERERQILDAACQE
Mflv_1253|M.gilvum_PYR-GCK -----------------------MLKSRTPERGRKGEQTRERLLGAAIAE
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
Mvan_3785|M.vanbaalenii_PYR-1 ---------------------MTEAAAPARRPNRRGQATRANMLEAALKS
. :* .
MMAR_1645|M.marinum_M FATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQ---
MUL_1881|M.ulcerans_Agy99 FATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQ---
MAV_3916|M.avium_104 FAAGGIGDRSLRRVAEAVGTSHRMLLHHFGSREGLLLAIVEEVERRQ---
MSMEG_4070|M.smegmatis_MC2_155 AVEHGFSELTWRPVAAALGVTSNTLVHHFGTKEQMFQAVLERLRARL---
Mb1510c|M.bovis_AF2122/97 FAEYGYDKATVRRLEQAIGMSRGAIFHHFRDKDALFFALAREDTERM---
Rv1474c|M.tuberculosis_H37Rv FAEYGYDKATVRRLEQAIGMSRGAIFHHFRDKDALFFALAREDTERM---
MAB_3199c|M.abscessus_ATCC_199 FGRSGYVGMSLAAVAAAVGVSKPMVLAYFGSKEQLYIACVERAGATVGDH
Mflv_1253|M.gilvum_PYR-GCK FKRDGMAAADIGAIVSAAGVAHGTFFFHFPTKEHVLVELENREQERMAA-
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
Mvan_3785|M.vanbaalenii_PYR-1 LASGDPGSVSANRIAKDIGATWGAVQYQFGDADGFWAAVLHRTAERRAD-
. : * : . * : . ..
MMAR_1645|M.marinum_M ---------------MSLLPELP---TSPAESFTAMWADVRRPELRQLER
MUL_1881|M.ulcerans_Agy99 ---------------MSLLPELP---TSPAESFTAMWADVRRPELRQLER
MAV_3916|M.avium_104 ---------------MRVLTELP---REPAEGFAAMWADLRRPELREFER
MSMEG_4070|M.smegmatis_MC2_155 ---------------LVATDELLGSRTDLASAARLAWELSSDPKRGPEFR
Mb1510c|M.bovis_AF2122/97 ---------------AAVASREG--LIGVMRDMLAAPDQFDWLATRLEIA
Rv1474c|M.tuberculosis_H37Rv ---------------AAVASREG--LIGVMRDMLAAPDQFDWLATRLEIA
MAB_3199c|M.abscessus_ATCC_199 IEAAMTAAPPTLALPRAVLQAIFQALAPRPSDWLVIWDQTLPEGSEALAA
Mflv_1253|M.gilvum_PYR-GCK --------------ELTRFYRRPHDVRATLTKAVTVLEALERRLGSRLFK
TH_4015|M.thermoresistible__bu -------------VRTDAGTEPKNPYERILRANRTYLEAYRANRAIMIVW
Mvan_3785|M.vanbaalenii_PYR-1 --------------VFASVDPDASLRDRVASIIDTLYDGLAEPDSRAIEN
MMAR_1645|M.marinum_M LFFECYSRAAQG-----------------------EKRFAQMVPRAVYGW
MUL_1881|M.ulcerans_Agy99 LFFECYSRAAQG-----------------------EKRFAQMVPHAVYGW
MAV_3916|M.avium_104 LFFECYSRAAQG-----------------------EKPFARMLPDAVDDW
MSMEG_4070|M.smegmatis_MC2_155 LFFAVYGRALQA-----------------------PEQFTNFLQRVVADW
Mb1510c|M.bovis_AF2122/97 RKLRNDPDFSRG-----------------------WAERSAELAAATTDR
Rv1474c|M.tuberculosis_H37Rv RKLRNDPDFSRG-----------------------WAERSAELAAATTDR
MAB_3199c|M.abscessus_ATCC_199 ARVARTRLAALAGQGVAAVGSAATQLRDAQDIGVLTQGWMGMVGAMITWW
Mflv_1253|M.gilvum_PYR-GCK DFLALHFSTRRPPS---------------------EEWSAHPVIVAVVED
TH_4015|M.thermoresistible__bu EQVASLNEHVEQLR----------------------REYSDRFAARIERA
Mvan_3785|M.vanbaalenii_PYR-1 LRAALPRDPAELER--------------------LYPQTAAELFSWGQSW
.
MMAR_1645|M.marinum_M LAEANAVT--EGSADPALVR----LGLAVIRG------------------
MUL_1881|M.ulcerans_Agy99 LAEASAVT--EGSADPALVR----LGLAVIRG------------------
MAV_3916|M.avium_104 LRQAETHA--GAPFDPAMAR----LGLAVIRG------------------
MSMEG_4070|M.smegmatis_MC2_155 MGSLCKAQ--GPEVEPAAARQRATLVIATIRG------------------
Mb1510c|M.bovis_AF2122/97 LRRQKQANRVRDDVPSDVLR---CYLDLVLDG------------------
Rv1474c|M.tuberculosis_H37Rv LRRQKQANRVRDDVPSDVLR---CYLDLVLDG------------------
MAB_3199c|M.abscessus_ATCC_199 IRHPEQSAEQMAERASRLIGIIASAGISEAEAPEGGAVPRPGTPVRGSGS
Mflv_1253|M.gilvum_PYR-GCK LERARDRGEIPADVDVMLRG------VSFLVG------------------
TH_4015|M.thermoresistible__bu IIRWQEAGLADPAIDPRYAA---AALSGMLSN------------------
Mvan_3785|M.vanbaalenii_PYR-1 LQ-ICHNAFAGLGVDPDRVREVATLIPGAMRG------------------
:
MMAR_1645|M.marinum_M ----------------------------LLLDLVATDDDAGVDAAARAFA
MUL_1881|M.ulcerans_Agy99 ----------------------------LLLDLVATDDDAGVDAAARAFA
MAV_3916|M.avium_104 ----------------------------LLLDLVATGDEAGVDAAARAFV
MSMEG_4070|M.smegmatis_MC2_155 ----------------------------LLLDLLATDDQDRVRDAAEAFL
Mb1510c|M.bovis_AF2122/97 ----------------------------LLARLASGEDPQRLAAVLDLVE
Rv1474c|M.tuberculosis_H37Rv ----------------------------LLARLASGEDPQRLAAVLDLVE
MAB_3199c|M.abscessus_ATCC_199 GQPLNAAFDLFGRRWAILVVWELRSGTKTLPELKAEMGDASSSVLATRLK
Mflv_1253|M.gilvum_PYR-GCK --------------------------LYALLITMPESREIRAPVIDEYVT
TH_4015|M.thermoresistible__bu ----------------------------FAYRWSVQDADYDLDTAAEQLS
Mvan_3785|M.vanbaalenii_PYR-1 -----------------------------LVSERQLGSYADLDVARRGLT
.
MMAR_1645|M.marinum_M QLLSR--------------------------------------
MUL_1881|M.ulcerans_Agy99 QLLSR--------------------------------------
MAV_3916|M.avium_104 NLLNAGA------------------------------------
MSMEG_4070|M.smegmatis_MC2_155 TSL----------------------------------------
Mb1510c|M.bovis_AF2122/97 NSVRRS-------------------------------------
Rv1474c|M.tuberculosis_H37Rv NSVRRS-------------------------------------
MAB_3199c|M.abscessus_ATCC_199 ELTAAHIVRNQDGQYSLTTVGKGLLVALAPLHLWAKAWSASVR
Mflv_1253|M.gilvum_PYR-GCK TYMDALHAA----------------------------------
TH_4015|M.thermoresistible__bu LLWANALGVRVPAHHEPAHA-----------------------
Mvan_3785|M.vanbaalenii_PYR-1 NALVAYLQAAD--------------------------------