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MISTSGTERRADGRQLRYQHRRGEIFDAVMAHVLEHGITGLSFRTLAAAVGVSHVTLRHHFGTKDQLLVE ILGAIGTRIVIPEQLGADDVEALWRRWNEPGAQRRSQLLFEAYAQAVRHPDEYRGFLDRIVTDWIETIRQ HAVQAGCPSDEAENFATLLIAQLRGLQFDLLASNDRARVAAALGTVVDGVRAKRAEWDASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0108 | - | - | 100% (201) | transcriptional regulatory protein |
| M. marinum M | MMAR_1597 | - | 1e-78 | 67.66% (201) | transcriptional regulatory protein |
| M. marinum M | MMAR_1645 | - | 2e-17 | 34.34% (166) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 6e-06 | 26.40% (197) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0925 | - | 4e-06 | 22.39% (201) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 6e-06 | 26.40% (197) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3193c | - | 9e-06 | 26.63% (184) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3916 | - | 7e-19 | 34.08% (179) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4070 | - | 8e-25 | 36.67% (180) | transcriptional regulator, TetR family protein, putative |
| M. thermoresistible (build 8) | TH_4019 | - | 8e-08 | 40.62% (64) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1881 | - | 7e-17 | 33.73% (166) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 7e-07 | 32.50% (80) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3916|M.avium_104 -----------MA-RTPDRQRRRELLDGLIAEFAAGGIGDRSLRRVAEAV
MUL_1881|M.ulcerans_Agy99 -----------MA-RTPDLQRRRQLLDALVEDFATHGVGDRSLRDVAAAV
MSMEG_4070|M.smegmatis_MC2_155 -----------MAGRPVDHQRRAELLDAIVDYAVEHGFSELTWRPVAAAL
Mb0335|M.bovis_AF2122/97 --------------MQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAA
Rv0328|M.tuberculosis_H37Rv --------------MQQQRTNRDKLLDGALACLRERGYGNTSSRDIARAA
MMAR_0108|M.marinum_M MISTSGTERRADGRQLRYQHRRGEIFDAVMAHVLEHGITGLSFRTLAAAV
TH_4019|M.thermoresistible__bu ---MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRAVAAEA
MAB_3193c|M.abscessus_ATCC_199 ----MSAAGTGTKRYPKGEAKRQEILSAALTVLERDGEAGASMRVIAKEA
Mflv_0925|M.gilvum_PYR-GCK MARSPAARRPPGGNQERAERTRRTVIDETVRYILDEGFAAPSVRRITERA
Mvan_4092|M.vanbaalenii_PYR-1 ----MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLEDIGAAA
* ::. * . :
MAV_3916|M.avium_104 GTSHRMLLHHFGSREGLLLAIVEEVERRQMRVLTELP-----REPAEGFA
MUL_1881|M.ulcerans_Agy99 GTSHRMLLHHFGSRDNLLVAVVEEVERRQMSLLPELP-----TSPAESFT
MSMEG_4070|M.smegmatis_MC2_155 GVTSNTLVHHFGTKEQMFQAVLERLRARLLVATDELLGSR--TDLASAAR
Mb0335|M.bovis_AF2122/97 GVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGPAGQIL
Rv0328|M.tuberculosis_H37Rv GVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGPAGQIL
MMAR_0108|M.marinum_M GVSHVTLRHHFGTKDQLLVEILGAIGTR--IVIPEQLG-------ADDVE
TH_4019|M.thermoresistible__bu GIPASLTAYYFATLDDLLVAALSSVADGYTERIREIIE-----RPGDRLR
MAB_3193c|M.abscessus_ATCC_199 NISLAGLMHYFPTRDVILTEIQRGADATFEERYRNSE------IELDPGE
Mflv_0925|M.gilvum_PYR-GCK GLTWGVVQYHFGDLGGLLMAVVDQGIAELTGALERLRTETANLPAEHRTE
Mvan_4092|M.vanbaalenii_PYR-1 GISGPAIYRHFPNKEALLVELLVGISTRLLAGAVEVVD-----RAGDDAD
. :* :: .
MAV_3916|M.avium_104 AMWADLRR--PELREFERLFFECYSRAAQGEKPFARMLP-----DAVDDW
MUL_1881|M.ulcerans_Agy99 AMWADVRR--PELRQLERLFFECYSRAAQGEKRFAQMVP-----HAVYGW
MSMEG_4070|M.smegmatis_MC2_155 LAWELSSD--PKRGPEFRLFFAVYGRALQAPEQFTNFLQ-----RVVADW
Mb0335|M.bovis_AF2122/97 AVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVD
Rv0328|M.tuberculosis_H37Rv AVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGYADVRQHSVD
MMAR_0108|M.marinum_M ALWRRWNE--PGAQRRSQLLFEAYAQAVRHPDEYRGFLD-----RIVTDW
TH_4019|M.thermoresistible__bu GLAELIVESAGPGRERALAERELSTLAARRPALQP----------VARRW
MAB_3193c|M.abscessus_ATCC_199 VLAQAMLDKANKPGSGTVYLSLAAAAAVDPEHPAGAYLRDRYERMRARIA
Mflv_0925|M.gilvum_PYR-GCK VVVDALWQAFSSPTSMAALEILISTRAARDSDVNAQLVD-------TMRQ
Mvan_4092|M.vanbaalenii_PYR-1 SALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPAAKRQVRRKQRQYVEIW
MAV_3916|M.avium_104 LRQAETHAGAPFDPA---MAR----LGLAVIRGLLLDLVATGDEAGVDAA
MUL_1881|M.ulcerans_Agy99 LAEASAVTEGSADPA---LVR----LGLAVIRGLLLDLVATDDDAGVDAA
MSMEG_4070|M.smegmatis_MC2_155 MGSLCKAQGPEVEPA---AARQRATLVIATIRGLLLDLLATDDQDRVRDA
Mb0335|M.bovis_AF2122/97 LAGAALAGTDIAPPE---NLSTIVSVLMAVIDGLMIQWIADPSATPRSTE
Rv0328|M.tuberculosis_H37Rv LAGAALAGTDIAPPE---NLSTIVSVLMAVIDGLMIQWIADPSATPRSTE
MMAR_0108|M.marinum_M IETIRQHAVQAGCPSD--EAENFATLLIAQLRGLQFDLLASNDRARVAAA
TH_4019|M.thermoresistible__bu RDNVAELASTLTDDP------QAIAALVAASDGLCTAILIDNAPADVDFA
MAB_3193c|M.abscessus_ATCC_199 AYVRGRQVDGTVPAHV--DADFAATALIAAADGIQIQWMSDPSIDMGEHM
Mflv_0925|M.gilvum_PYR-GCK FTELGRHLGEDLDAP---QATEIGNLIWATLRGIVLAQMVSPQPLDTSRD
Mvan_4092|M.vanbaalenii_PYR-1 VDVLRRRTPGLTETDARLMAHAAFGLLNSTPHGVKPGLNKAAEASSRTVL
: *:
MAV_3916|M.avium_104 ARAFVNLLNAGA-------
MUL_1881|M.ulcerans_Agy99 ARAFAQLLSR---------
MSMEG_4070|M.smegmatis_MC2_155 AEAFLTSL-----------
Mb0335|M.bovis_AF2122/97 VIRALASIGAVVTSQLR--
Rv0328|M.tuberculosis_H37Rv VIRALASIGAVVTSQLR--
MMAR_0108|M.marinum_M LGTVVDGVRAKRAEWDASR
TH_4019|M.thermoresistible__bu HGVLRRALGVPAEHQP---
MAB_3193c|M.abscessus_ATCC_199 RRVWELLLR----------
Mflv_0925|M.gilvum_PYR-GCK RRTLVDVLNTYMRAKGR--
Mvan_4092|M.vanbaalenii_PYR-1 RTMTVAALTSAGRRA----
: