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TAAKPALVPVRQIPAHELVVDQMRRALELGQFRPGDRLPTERELSEMLDVSRTTVRTAVAVLEREGLIAV RRGRGGGFTVQAPEYDPVEMRREMRRNKRAVRDAFDYRVVVETGATRLAAERRRAADLNDLHKLLNGMDE ALKTALDDQSPKHTTDFQTLDSAFHLGIAQAAQNDRLLDAVADARRRMWLPVGAIFGRLEPNANDYHESI LEAIENREPELAAARMEAHINDTRHTIESWLKR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3822 | - | - | 100% (244) | regulatory protein GntR, HTH |
M. smegmatis MC2 155 | MSMEG_1117 | - | 1e-23 | 34.19% (234) | transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_2599 | - | 6e-23 | 34.30% (242) | GntR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3086c | - | 3e-10 | 27.52% (218) | GntR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_4061 | - | 4e-26 | 35.74% (235) | regulatory protein GntR, HTH |
M. tuberculosis H37Rv | Rv3060c | - | 3e-10 | 27.52% (218) | GntR family transcriptional regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2272c | - | 2e-11 | 29.38% (177) | putative transcriptional regulator, GntR |
M. marinum M | MMAR_0749 | - | 2e-16 | 31.05% (219) | GntR family transcriptional regulator |
M. avium 104 | MAV_2542 | - | 3e-13 | 36.69% (139) | regulatory protein GntR, HTH |
M. thermoresistible (build 8) | TH_4115 | - | 2e-13 | 29.20% (226) | PUTATIVE - |
M. ulcerans Agy99 | MUL_1381 | - | 2e-16 | 31.05% (219) | GntR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_0606 | - | 1e-118 | 86.53% (245) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3822|M.smegmatis_MC2_155 MTAAKP---------ALVPVRQIPAHELVVDQMRRALELGQFRPGDRLPT Mvan_0606|M.vanbaalenii_PYR-1 MTAERPS--------ALSPVRQIPAHELVVDQMRRALELGQFRPGDRLPT Mflv_4061|M.gilvum_PYR-GCK MAAPDPADSSDASEALLRPVRPLNAFEDTVERLLQTIRLGVLTPGESLPP MMAR_0749|M.marinum_M ----------------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPT MUL_1381|M.ulcerans_Agy99 -------------------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPT MAB_2272c|M.abscessus_ATCC_199 ----------------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPT Mb3086c|M.bovis_AF2122/97 ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS Rv3060c|M.tuberculosis_H37Rv ------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGS MAV_2542|M.avium_104 -MPKREPLAPMATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPY TH_4115|M.thermoresistible__bu ---------------------VQSSYIQVADQLRDLILRGDLAVGQKLPS : : * : MSMEG_3822|M.smegmatis_MC2_155 ERELSEMLDVSRTTVRTAVAVLEREGLIAVRRGRGGGFTVQAPEYDPVEM Mvan_0606|M.vanbaalenii_PYR-1 ERELSEMLDVSRTTVRTAVAVLERDGLIAVRRGRGGGFTVQAPPVDPAEM Mflv_4061|M.gilvum_PYR-GCK ERELAARLGVSRDTVREAIKSLADAGYLVSRRGRYGGTFLADALPAPRAD MMAR_0749|M.marinum_M EPELCEMTGTARNTVREAVQALVHVGILERRQG--SGTYVIADVEQGSAL MUL_1381|M.ulcerans_Agy99 EPELCEMTGTARNTVREAVQALVHVGILERRQG--SGTYVIADVEQGSAL MAB_2272c|M.abscessus_ATCC_199 EPELCELTGTSRNTIREAVQALVHAGMLERRQG--SGTYVLS-LGGSSAI Mb3086c|M.bovis_AF2122/97 ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATR Rv3060c|M.tuberculosis_H37Rv ESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATR MAV_2542|M.avium_104 EAELMDHFQVSRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPEIVAR TH_4115|M.thermoresistible__bu EAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSER--L * : .:* :* *: : *:* * : MSMEG_3822|M.smegmatis_MC2_155 RREMRRNKR--AVRDAFDYRVVVETGATRLAAERRRAADLNDLHKLLNGM Mvan_0606|M.vanbaalenii_PYR-1 RRELRRNKR--AIRDAFDYRIIVETGATRLAAERRRAIELADLRKLLVGM Mflv_4061|M.gilvum_PYR-GCK GTEMHRDD----IDDAVRLREILEVGAARMAAVR----------TLAAVE MMAR_0749|M.marinum_M AEYFAAAR----ERDLWELREAVEVTAAVLSARRRDAADIEDLRALLARR MUL_1381|M.ulcerans_Agy99 AEYFAAAR----ERDLWELREAVEVTAAVLSARRRDAADIEDLRVLLARR MAB_2272c|M.abscessus_ATCC_199 ADYFAAAN----NRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRR Mb3086c|M.bovis_AF2122/97 AVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR-A Rv3060c|M.tuberculosis_H37Rv AVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR-A MAV_2542|M.avium_104 PAGFLLEMAGTTLADVMTARMGIEPYAARLLAEDGTAAAHRELRELIEEI TH_4115|M.thermoresistible__bu EGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAALAAAARGGDQVEELK : : * :: : . : MSMEG_3822|M.smegmatis_MC2_155 DEALKTALDDQSPKHTTDFQTLDSAFHLGIAQAAQNDRLLDAVADARRRM Mvan_0606|M.vanbaalenii_PYR-1 EAALDAALKDQSAQRTTEFQTLDTAFHMGIAQAAQNDRLLDAVADARRRM Mflv_4061|M.gilvum_PYR-GCK REALRSRLTDVRGADPADYRRLDSRLHLAIAEAAGVPSLVPLVAQNRMRL MMAR_0749|M.marinum_M NELWSREPAN--DKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTI MUL_1381|M.ulcerans_Agy99 NELWSREPAN--DKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTI MAB_2272c|M.abscessus_ATCC_199 NELWAPHHVE--PHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLM Mb3086c|M.bovis_AF2122/97 EERWRPGLPP----PPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKS Rv3060c|M.tuberculosis_H37Rv EERWRPGLPP----PPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKS MAV_2542|M.avium_104 PAAWETGKLG---AASTALHRRLVELSGNATLTVIVGMLHEIFERHMTAA TH_4115|M.thermoresistible__bu RTAAMVDPAD-----QEAAMQQSADFHSAILRASGNKLLEAMGRPVSAVA MSMEG_3822|M.smegmatis_MC2_155 WLPVG--AIFGRLEPNANDYHESILEAIENREPELAAARMEAHINDTRHT Mvan_0606|M.vanbaalenii_PYR-1 WLPVG--AIFGRLEPNANDYHESILEAIENRDPELAGSRMEAHINDTRNT Mflv_4061|M.gilvum_PYR-GCK NELLDRIPLMTRNIAHSDEQHEAIVSAILAGDADTAAQTMAAHVWGSAAL MMAR_0749|M.marinum_M HRAVE--AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRP- MUL_1381|M.ulcerans_Agy99 HRAVE--AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRR- MAB_2272c|M.abscessus_ATCC_199 DHYMR--GNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLS Mb3086c|M.bovis_AF2122/97 GTQSA--GEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGW Rv3060c|M.tuberculosis_H37Rv GTQSA--GEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGW MAV_2542|M.avium_104 FLSVQN-VVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMENASAE TH_4115|M.thermoresistible__bu RSKFRRTVPGLEFWERNQRAHQELLKAILAGDENLAYELATRHIDEDLSP : : : : * . MSMEG_3822|M.smegmatis_MC2_155 IESWLKR------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 LESWLKR------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK LHGFLD-------------------------------------------- MMAR_0749|M.marinum_M -------------------------------------------------- MUL_1381|M.ulcerans_Agy99 -------------------------------------------------- MAB_2272c|M.abscessus_ATCC_199 RDQPGRNFPHHPHD------------------------------------ Mb3086c|M.bovis_AF2122/97 LQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAA Rv3060c|M.tuberculosis_H37Rv LQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAA MAV_2542|M.avium_104 LLKGHEKTKVRDIMH----------------------------------- TH_4115|M.thermoresistible__bu YYLPPEEADRDGAGA----------------------------------- MSMEG_3822|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_0749|M.marinum_M -------------------------------------------------- MUL_1381|M.ulcerans_Agy99 -------------------------------------------------- MAB_2272c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 SGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLV Rv3060c|M.tuberculosis_H37Rv SGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLV MAV_2542|M.avium_104 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MSMEG_3822|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_0749|M.marinum_M -------------------------------------------------- MUL_1381|M.ulcerans_Agy99 -------------------------------------------------- MAB_2272c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 VTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPE Rv3060c|M.tuberculosis_H37Rv VTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPE MAV_2542|M.avium_104 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MSMEG_3822|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_0749|M.marinum_M -------------------------------------------------- MUL_1381|M.ulcerans_Agy99 -------------------------------------------------- MAB_2272c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 VASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLIL Rv3060c|M.tuberculosis_H37Rv VASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLIL MAV_2542|M.avium_104 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MSMEG_3822|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_0606|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_4061|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_0749|M.marinum_M -------------------------------------------------- MUL_1381|M.ulcerans_Agy99 -------------------------------------------------- MAB_2272c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3086c|M.bovis_AF2122/97 VELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRH Rv3060c|M.tuberculosis_H37Rv VELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRH MAV_2542|M.avium_104 -------------------------------------------------- TH_4115|M.thermoresistible__bu -------------------------------------------------- MSMEG_3822|M.smegmatis_MC2_155 --------- Mvan_0606|M.vanbaalenii_PYR-1 --------- Mflv_4061|M.gilvum_PYR-GCK --------- MMAR_0749|M.marinum_M --------- MUL_1381|M.ulcerans_Agy99 --------- MAB_2272c|M.abscessus_ATCC_199 --------- Mb3086c|M.bovis_AF2122/97 LDAAASWWL Rv3060c|M.tuberculosis_H37Rv LDAAASWWL MAV_2542|M.avium_104 --------- TH_4115|M.thermoresistible__bu ---------