For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
STEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSRSVLREAVRLVEHHQVARMRRG PNGGLFICEPNAGPATRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEERW RPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQSAGEAVEAAGQVHNEHSDIVAAVTA GDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAA SGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQYR KPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGN TMLDLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3060c | - | - | 100% (490) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) |
| M. tuberculosis H37Rv | Rv0494 | - | 2e-05 | 26.84% (231) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3086c | - | 0.0 | 100.00% (490) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2114 | - | 7e-15 | 32.58% (178) | GntR domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2272c | - | 2e-13 | 27.98% (218) | putative transcriptional regulator, GntR |
| M. marinum M | MMAR_1630 | - | 0.0 | 72.21% (493) | transcriptional regulatory protein |
| M. avium 104 | MAV_3932 | - | 0.0 | 72.82% (493) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 5e-15 | 27.71% (231) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_2873 | - | 1e-19 | 29.54% (237) | PUTATIVE regulatory protein GntR, HTH |
| M. ulcerans Agy99 | MUL_3832 | - | 1e-12 | 27.46% (244) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4590 | - | 3e-14 | 27.56% (225) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3060c|M.tuberculosis_H37Rv --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Mb3086c|M.bovis_AF2122/97 --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
MMAR_1630|M.marinum_M -----------MGQLSVEPDVIRADKRAARVARHIEAEIVRRGWTVGASL
MAV_3932|M.avium_104 --------------MNAEPRTGPAKTLASALARDIEAEIVRRGWAVGESL
Mflv_2114|M.gilvum_PYR-GCK MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mvan_4590|M.vanbaalenii_PYR-1 MTRNTPLAPMIGPDAVASRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MSMEG_5201|M.smegmatis_MC2_155 MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
TH_2873|M.thermoresistible__bu ----------VEDDMEVT--SLREPKMADRVATVLRRMFIRGEIPEGTML
MUL_3832|M.ulcerans_Agy99 -----MTALGIGPDPRRR---LSAPRIAEIVADELRRQIIDGELADGDLL
MAB_2272c|M.abscessus_ATCC_199 ------------------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARI
:: :. .: * :
Rv3060c|M.tuberculosis_H37Rv GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Mb3086c|M.bovis_AF2122/97 GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
MMAR_1630|M.marinum_M GSEGALQQRYGVSRSVLREAVRLVEHHQVARMRRGPNGGLLICAPDAGPA
MAV_3932|M.avium_104 GSEPALQQRFGVSRSVLREAVRLVEHHQVARMRRGPNGGLYICEPDAGPA
Mflv_2114|M.gilvum_PYR-GCK PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
Mvan_4590|M.vanbaalenii_PYR-1 PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MSMEG_5201|M.smegmatis_MC2_155 PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
TH_2873|M.thermoresistible__bu PPESELMERFGVSRPTLREAFRVLESESLIVVQRGVRGGARVTRPRRETL
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAB_2272c|M.abscessus_ATCC_199 PTEPELCELTGTSRNTIREAVQALVHAGMLERRQGS--GTYVLSLGG---
: * .* :***.: : : ::* * :
Rv3060c|M.tuberculosis_H37Rv TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----IERL
Mb3086c|M.bovis_AF2122/97 TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----IERL
MMAR_1630|M.marinum_M TRAVVIYLEYLGITLGELLDARLVFEPLAASLAAEHIDEAG-----IDRL
MAV_3932|M.avium_104 TRAVVIYLEYLGTTLADLLNARLVLEPLAASLAAERIDEAG-----IARL
Mflv_2114|M.gilvum_PYR-GCK ARPAGLLLELSGATIADLLTAKSAIEPMAARLLAE--SGSAAAFDELEQL
Mvan_4590|M.vanbaalenii_PYR-1 ARPAGLLLELSGATIADLLTAKSGIEPMAARLLAE--SGSPEAFDELERM
MSMEG_5201|M.smegmatis_MC2_155 ARPVGLLLELSGADIADLLVARSAIEPMAARLLAE--NGTEEQFAELDRM
TH_2873|M.thermoresistible__bu ARYAGLILEYEGVTVKDVYEARVALEVPMVVQLAK--DRNPAVIAELERI
MUL_3832|M.ulcerans_Agy99 AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MAB_2272c|M.abscessus_ATCC_199 --SSAIADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDD-----IEQL
: . :: :* . *: . : ::
Rv3060c|M.tuberculosis_H37Rv RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
Mb3086c|M.bovis_AF2122/97 RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
MMAR_1630|M.marinum_M RAVLRAEEQRKPGLPAVRDEFHVALARQSKNPVLQLFIEILMRLTRRYAL
MAV_3932|M.avium_104 RAVLHAEQQWRPGLPMPRDEFHIALAEQSKNPVLQLFIKVLMRLTTRYAL
Mflv_2114|M.gilvum_PYR-GCK LEELVADSHQSPRLAEATGAFHLRVVQLSGNATLSIVAGMLHEITVRHTA
Mvan_4590|M.vanbaalenii_PYR-1 LEELAADSHKSSRLAEATGLFHLRVVQLSGNATLSIVAGMLHEITVRHTA
MSMEG_5201|M.smegmatis_MC2_155 LEEHIPSDWQSDRLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQ
TH_2873|M.thermoresistible__bu VEAESKLEPGAETVSQLT-DFHGAIARLSGNKTLQIVTDMLHHVIEKANR
MUL_3832|M.ulcerans_Agy99 NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MAB_2272c|M.abscessus_ATCC_199 RALLVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDS
. :
Rv3060c|M.tuberculosis_H37Rv KSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
Mb3086c|M.bovis_AF2122/97 KSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
MMAR_1630|M.marinum_M TSRTDTVA----EAFEAVDQMHNDHAAIAAAVTAGDSARAKTLSEQHVQQ
MAV_3932|M.avium_104 QSRTDSET----EALEAVDHLHTHHSRIVAAVTAGDPARAKTLSERHVEA
Mflv_2114|M.gilvum_PYR-GCK FVFNERRP----VSKADYETLLRSYRRLLQFLRSRDADGAEAHWRRHLDK
Mvan_4590|M.vanbaalenii_PYR-1 FVFNERRP----VSKADYDTLLRSYRKLMQFLRAGDAVGAEAHWRKHLDT
MSMEG_5201|M.smegmatis_MC2_155 FLFREHRP----VSKSDYDKLMRSYRKLMQIMRSGDGDAAEAHWRTHLDT
TH_2873|M.thermoresistible__bu SLQPTEGT----RAEQAVKKSTKTHRMVLDYIKAGDAEKAGELWQKHLQK
MUL_3832|M.ulcerans_Agy99 QWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLAD
MAB_2272c|M.abscessus_ATCC_199 LLGLMDHYMRG-NPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAE
. : : : * * .
Rv3060c|M.tuberculosis_H37Rv VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
Mb3086c|M.bovis_AF2122/97 VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
MMAR_1630|M.marinum_M VTGWLQQHQPGGDAKL-----AHVPRRSLRLDSETPPGKLAEVLAATIAD
MAV_3932|M.avium_104 VTAWLQRHHAGDRNRG------RTPRR--PLNSEVPQGKLAEMLAATIGD
Mflv_2114|M.gilvum_PYR-GCK TRELLLAG--------------------------LESVPVRDVMG-----
Mvan_4590|M.vanbaalenii_PYR-1 TRELLLTG--------------------------LESVPVRDVMG-----
MSMEG_5201|M.smegmatis_MC2_155 ARALMLQG--------------------------LESVKVRDVMG-----
TH_2873|M.thermoresistible__bu AGEYLLSG--------------------------TEMSTVVDLLE-----
MUL_3832|M.ulcerans_Agy99 TQTYVLSG--------------------------RAEQRIYALSPQALSR
MAB_2272c|M.abscessus_ATCC_199 LRLSRDQP-----------------------------GRNFPHHPHD---
Rv3060c|M.tuberculosis_H37Rv DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
Mb3086c|M.bovis_AF2122/97 DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
MMAR_1630|M.marinum_M DIAASGWQLDSVFGTETALLQRYRVSRAALREAVRLLEYHSVARMRRGPG
MAV_3932|M.avium_104 DIAADGWRVGSVFGTETALLQRYRVSRAVFREAVRLLEYHSIAHMRRGPG
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_2873|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 PRDMRRP-------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3060c|M.tuberculosis_H37Rv GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
Mb3086c|M.bovis_AF2122/97 GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
MMAR_1630|M.marinum_M GGLVVTKPQSQASIDTIALYLQYRQPSREDLRCVRDAIEIANVAKVVEQR
MAV_3932|M.avium_104 GGLVIAEPAAQASIDTIALYLQYRDPSREDLRCVRDAIEIDNVAKVVKRL
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_2873|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3060c|M.tuberculosis_H37Rv SEPEVASFLDTLGRP---RLDNPTDDVRAAAVEEFRFHVGLARAAGNTML
Mb3086c|M.bovis_AF2122/97 SEPEVASFLDTLGRP---RLDNPTDDVRAAAVEEFRFHVGLARAAGNTML
MMAR_1630|M.marinum_M ARPEVASVLDELVVASDFAFEDAADAARKVAVEEFGFHVGLAQLAGNALL
MAV_3932|M.avium_104 AEPQVAAFVASRRSGLPDDSRQTPDDVRRAIAEEFDFHVGLAQLAGNAPL
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_2873|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3060c|M.tuberculosis_H37Rv DLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLA
Mb3086c|M.bovis_AF2122/97 DLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLA
MMAR_1630|M.marinum_M DLFLRIIVELFQRHWSSTEHQQPTFNDVGAVEHAHQRIREAIIAGDDSLA
MAV_3932|M.avium_104 DLFLRIIVELFRRHWSSTGQALPTWSDVRAVHHAHLRIADAVAAGDLSVA
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_2873|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Rv3060c|M.tuberculosis_H37Rv RCRTRRHLDAAASWWL
Mb3086c|M.bovis_AF2122/97 RCRTRRHLDAAASWWL
MMAR_1630|M.marinum_M RYRIRRHLDAAASWWL
MAV_3932|M.avium_104 SYRLRRHLDAAASWWL
Mflv_2114|M.gilvum_PYR-GCK ----------------
Mvan_4590|M.vanbaalenii_PYR-1 ----------------
MSMEG_5201|M.smegmatis_MC2_155 ----------------
TH_2873|M.thermoresistible__bu ----------------
MUL_3832|M.ulcerans_Agy99 ----------------
MAB_2272c|M.abscessus_ATCC_199 ----------------