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QPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGTSRNTIREAVQALVHAGMLERRQGSGTY VLSLGGSSAIADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAPHHVEPHNV EEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYMRGNPIGAECSFEHEHTRLVESVIAGDIGGATS ATEQLFAELRLSRDQPGRNFPHHPHD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2272c | - | - | 100% (237) | putative transcriptional regulator, GntR |
| M. abscessus ATCC 19977 | MAB_4644c | - | 2e-27 | 38.50% (213) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3018 | - | 3e-09 | 29.10% (134) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3086c | - | 7e-14 | 27.98% (218) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 7e-30 | 38.94% (208) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv3060c | - | 7e-14 | 27.98% (218) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0749 | - | 6e-70 | 59.91% (222) | GntR family transcriptional regulator |
| M. avium 104 | MAV_3932 | - | 2e-14 | 29.15% (223) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_2794 | - | 7e-35 | 40.10% (202) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4115 | - | 3e-15 | 28.02% (207) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1381 | - | 3e-68 | 59.36% (219) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0952 | - | 6e-30 | 37.44% (219) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3086c|M.bovis_AF2122/97 ------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQ
Rv3060c|M.tuberculosis_H37Rv ------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQ
MAV_3932|M.avium_104 ------MNAEPRTGPAKTLASALARDIEAEIVRRGWAVGESLGSEPALQQ
MMAR_0749|M.marinum_M ----------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MUL_1381|M.ulcerans_Agy99 -------------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MAB_2272c|M.abscessus_ATCC_199 ----------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCE
Mflv_0016|M.gilvum_PYR-GCK MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNETVLVE
Mvan_0952|M.vanbaalenii_PYR-1 --------MPLSTARRTGLVDQVIEQLRRAVAGGEWRVGERIPNETVLVE
MSMEG_2794|M.smegmatis_MC2_155 --------MPLASTRRTGLVDQVIEQLRASVSSGEWPVGTKIPTEPELAD
TH_4115|M.thermoresistible__bu ---------------VQSSYIQVADQLRDLILRGDLAVGQKLPSEAEMAP
: :. : :* : .*. :
Mb3086c|M.bovis_AF2122/97 RFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYL
Rv3060c|M.tuberculosis_H37Rv RFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYL
MAV_3932|M.avium_104 RFGVSRSVLREAVRLVEHHQVARMRRGPNGGLYICEPDAGPATRAVVIYL
MMAR_0749|M.marinum_M MTGTARNTVREAVQALVHVGILERRQG-SGTYVIADVEQGSALAEY----
MUL_1381|M.ulcerans_Agy99 MTGTARNTVREAVQALVHVGILERRQG-SGTYVIADVEQGSALAEY----
MAB_2272c|M.abscessus_ATCC_199 LTGTSRNTIREAVQALVHAGMLERRQG-SGTYVLS-LGGSSAIADY----
Mflv_0016|M.gilvum_PYR-GCK KFGVGRNTVREAVRALAHAGILEVRQG-DGTYVRATSEVSGALRR-----
Mvan_0952|M.vanbaalenii_PYR-1 SLGVGRNTVREAVRALAHAGILEVRQG-DGTYVRATSEVSGALRR-----
MSMEG_2794|M.smegmatis_MC2_155 TLGVGRNTLREAVRALAHSGILEVRQG-DGTYVRATSEVSGALRR-----
TH_4115|M.thermoresistible__bu LLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERLEGMFNTSF
..*..:***:: : : . *:* .* .
Mb3086c|M.bovis_AF2122/97 EYLGTT----IGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEER
Rv3060c|M.tuberculosis_H37Rv EYLGTT----IGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEER
MAV_3932|M.avium_104 EYLGTT----LADLLNARLVLEPLAASLAAERIDEAGIARLRAVLHAEQQ
MMAR_0749|M.marinum_M -FAAAR----ERDLWELREAVEVTAAVLSARRRDAADIEDLRALLARRNE
MUL_1381|M.ulcerans_Agy99 -FAAAR----ERDLWELREAVEVTAAVLSARRRDAADIEDLRVLLARRNE
MAB_2272c|M.abscessus_ATCC_199 -FAAAN----NRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNE
Mflv_0016|M.gilvum_PYR-GCK -LCGEE----LREVLEVRRALEVEAARLAASRRTPADVAEMRGLLARRD-
Mvan_0952|M.vanbaalenii_PYR-1 -LCGAE----LREVLQVRRALEVEGARLAAAHCTPADIAEMRTLLARRD-
MSMEG_2794|M.smegmatis_MC2_155 -LCGSE----LREVLQVRRCLEVEGARLAASNRTDADLAELRAFLDR---
TH_4115|M.thermoresistible__bu SMLALTNQVDARSFLQAMRALEGPAAALAAAARGGDQVEELKRTAAMVDP
. .. :* .* *:* : ::
Mb3086c|M.bovis_AF2122/97 ---WRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQS
Rv3060c|M.tuberculosis_H37Rv ---WRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQS
MAV_3932|M.avium_104 ---WRPGLPMPRDEFHIALAEQSKNPVLQLFIKVLMRLTTRYALQSRTDS
MMAR_0749|M.marinum_M LWSREPANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAV
MUL_1381|M.ulcerans_Agy99 LWSREPANDKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAV
MAB_2272c|M.abscessus_ATCC_199 LWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYM
Mflv_0016|M.gilvum_PYR-GCK ----ERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTASV
Mvan_0952|M.vanbaalenii_PYR-1 ----ECAATDDTDAFARTDAEFHLAVVRGSGNRTLTELYRGLIEVVTASV
MSMEG_2794|M.smegmatis_MC2_155 ------TETSDDDDFVHSDTAFHLAVVRASHNSVLIELYRGLIEAITASV
TH_4115|M.thermoresistible__bu ---------ADQEAAMQQSADFHSAILRASGNKLLEAMGRPVSAVARSKF
: :
Mb3086c|M.bovis_AF2122/97 AGEA--VEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQH
Rv3060c|M.tuberculosis_H37Rv AGEA--VEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQH
MAV_3932|M.avium_104 ETEA--LEAVDHLHTHHSRIVAAVTAGDPARAKTLSERHVEAVTAWLQRH
MMAR_0749|M.marinum_M EAGP--VGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRP-----
MUL_1381|M.ulcerans_Agy99 EAGP--VGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRR-----
MAB_2272c|M.abscessus_ATCC_199 RGNP--IGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQP
Mflv_0016|M.gilvum_PYR-GCK AHTR--HVPVD--VCDHGVLLDHIAAGDPDLAARTAGEFLDRIINGLGSA
Mvan_0952|M.vanbaalenii_PYR-1 ATTR--HVPVE--MVDHGVLVDQIAAGDAEQAARTAGELLDRILAGVDSA
MSMEG_2794|M.smegmatis_MC2_155 ATAS--ARPDG--KVSHRGLVEAIAAGDVERAGREAGGFLDDLLAQTPDP
TH_4115|M.thermoresistible__bu RRTVPGLEFWERNQRAHQELLKAILAGDENLAYELATRHIDEDLSPYYLP
* :: : *** * : .
Mb3086c|M.bovis_AF2122/97 QRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQ
Rv3060c|M.tuberculosis_H37Rv QRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQ
MAV_3932|M.avium_104 HAGD----RN--RGRTPRRP--LNSEVPQGKLAEMLAATIGDDIAADGWR
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 GRNFPHHPHD----------------------------------------
Mflv_0016|M.gilvum_PYR-GCK DSS-----------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 DSC-----------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 QG------------------------------------------------
TH_4115|M.thermoresistible__bu PEEADRDGAGA---------------------------------------
Mb3086c|M.bovis_AF2122/97 VGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTP
Rv3060c|M.tuberculosis_H37Rv VGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTP
MAV_3932|M.avium_104 VGSVFGTETALLQRYRVSRAVFREAVRLLEYHSIAHMRRGPGGGLVIAEP
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
TH_4115|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 QPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASF
Rv3060c|M.tuberculosis_H37Rv QPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASF
MAV_3932|M.avium_104 AAQASIDTIALYLQYRDPSREDLRCVRDAIEIDNVAKVVKRLAEPQVAAF
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
TH_4115|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 LDTLGRPRLDN---PTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILV
Rv3060c|M.tuberculosis_H37Rv LDTLGRPRLDN---PTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILV
MAV_3932|M.avium_104 VASRRSGLPDDSRQTPDDVRRAIAEEFDFHVGLAQLAGNAPLDLFLRIIV
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
TH_4115|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 ELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHL
Rv3060c|M.tuberculosis_H37Rv ELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHL
MAV_3932|M.avium_104 ELFRRHWSSTGQALPTWSDVRAVHHAHLRIADAVAAGDLSVASYRLRRHL
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
TH_4115|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 DAAASWWL
Rv3060c|M.tuberculosis_H37Rv DAAASWWL
MAV_3932|M.avium_104 DAAASWWL
MMAR_0749|M.marinum_M --------
MUL_1381|M.ulcerans_Agy99 --------
MAB_2272c|M.abscessus_ATCC_199 --------
Mflv_0016|M.gilvum_PYR-GCK --------
Mvan_0952|M.vanbaalenii_PYR-1 --------
MSMEG_2794|M.smegmatis_MC2_155 --------
TH_4115|M.thermoresistible__bu --------