For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSADPDPQPTAEAADALLRPVRLGNAFEDTVGRLLETIRLGVLGPGESLPPERELATRLGVSRDTVREAI KSLADAGYLVSRRGRYGGTFLADELPSHTADTPRPTHEEIDDALRLREILEVGAARMAAGRTLSAAERDG LWSRLADVRAAEGTDDYRRLDSRLHLAIAEAAGSPSLVPLIAENRMRINGLLDRIPLLPRNIAHSDDQHE AIVMAILAGDADRAATAMLDHVSGSAALLHGFLD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2599 | - | - | 100% (244) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1117 | - | 8e-36 | 41.48% (229) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3822 | - | 6e-23 | 34.30% (242) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 1e-08 | 43.28% (67) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4061 | - | 8e-98 | 77.69% (242) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0586 | - | 1e-08 | 43.28% (67) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 3e-13 | 31.75% (211) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0749 | - | 3e-11 | 28.51% (221) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1744 | - | 3e-10 | 30.84% (214) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4115 | - | 1e-10 | 28.12% (224) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1381 | - | 2e-11 | 29.61% (206) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2282 | - | 2e-96 | 77.55% (245) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0601|M.bovis_AF2122/97 --------------------------------------------------
Rv0586|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4061|M.gilvum_PYR-GCK -MAAPDPADS------------------------------SD--------
Mvan_2282|M.vanbaalenii_PYR-1 MSAVPEPTDERLREEQTASDERLREEQTASDERLREEQTASDGADATAEQ
MSMEG_2599|M.smegmatis_MC2_155 MSADPDPQPT------------------------------AE--------
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
TH_4115|M.thermoresistible__bu --------------------------------------------------
MAV_1744|M.avium_104 ----------------------------------------------MQQR
Mb0601|M.bovis_AF2122/97 ----MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGV
Rv0586|M.tuberculosis_H37Rv ----MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAELLGV
Mflv_4061|M.gilvum_PYR-GCK -ASEALLRPVRPLNAFEDTVERLLQTIRLGVLTPGESLPPERELAARLGV
Mvan_2282|M.vanbaalenii_PYR-1 IAADALLRPVRPLNAFEDTVERLLQTIRLGVLRPGESLPPERELATRLGV
MSMEG_2599|M.smegmatis_MC2_155 -AADALLRPVRLGNAFEDTVGRLLETIRLGVLGPGESLPPERELATRLGV
MAB_4644c|M.abscessus_ATCC_199 -----MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPGEVALCEEFGV
MMAR_0749|M.marinum_M ------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGT
MUL_1381|M.ulcerans_Agy99 ---------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGT
TH_4115|M.thermoresistible__bu -----------VQSSYIQVADQLRDLILRGDLAVGQKLPSEAEMAPLLGV
MAV_1744|M.avium_104 SDKAGPVTAAAGVPLHRQLFLVLHDEIDRGVIAPGEALPTEQTLCDQFGV
: : : * * :* * :. *.
Mb0601|M.bovis_AF2122/97 SRPAVREALKRLSAAGLVEVRQGDVTTVRDFR--RHAGLDLLPRLLFRNG
Rv0586|M.tuberculosis_H37Rv SRPAVREALKRLSAAGLVEVRQGDVTTVRDFR--RHAGLDLLPRLLFRNG
Mflv_4061|M.gilvum_PYR-GCK SRDTVREAIKSLADAGYLVSRRGRYGGTFLAD--ALPAPRADGTEMHRDD
Mvan_2282|M.vanbaalenii_PYR-1 SRDTVREAIKSLADAGYLVSRRGRYGGTFIAD--ALPAPRTGDVAFSRTD
MSMEG_2599|M.smegmatis_MC2_155 SRDTVREAIKSLADAGYLVSRRGRYGGTFLAD--ELPSHTADTPRPTHEE
MAB_4644c|M.abscessus_ATCC_199 SRATVREAIRDLKTKGLVSTRQG--AGVFVTS--DRPLG-QWDRVLAAAE
MMAR_0749|M.marinum_M ARNTVREAVQALVHVGILERRQG--SGTYVIA--DVEQGSALAEYFAAAR
MUL_1381|M.ulcerans_Agy99 ARNTVREAVQALVHVGILERRQG--SGTYVIA--DVEQGSALAEYFAAAR
TH_4115|M.thermoresistible__bu SRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERLEGMFNTSFSMLA
MAV_1744|M.avium_104 SRITVRRALADLAAQGYIERRQGVGSFVRQHDPADVPTGRSYLQGLRQTQ
:* ::*.*: * : *:* .
Mb0601|M.bovis_AF2122/97 ELDISVVRSILEARLRNFPKVAELA----------AERNEPELAELLQDS
Rv0586|M.tuberculosis_H37Rv ELDISVVRSILEARLRNFPKVAELA----------AERNEPELAELLQDS
Mflv_4061|M.gilvum_PYR-GCK IDDAVRLREILEVGAARMAAVR-------------TLAAVEREALRSR--
Mvan_2282|M.vanbaalenii_PYR-1 IDDALRLREILETGAARMAACR-------------TLSATEREALWSR--
MSMEG_2599|M.smegmatis_MC2_155 IDDALRLREILEVGAARMAAGR-------------TLSAAERDGLWSR--
MAB_4644c|M.abscessus_ATCC_199 IDAVVEIRRLLEVQAAGLAAERRNR----------SDVAAIRRALVAR--
MMAR_0749|M.marinum_M ERDLWELREAVEVTAAVLSARRRDA----------ADIEDLRALLARRNE
MUL_1381|M.ulcerans_Agy99 ERDLWELREAVEVTAAVLSARRRDA----------ADIEDLRVLLARRNE
TH_4115|M.thermoresistible__bu LTNQVDARSFLQAMRALEGPAAALA----------AAARGGDQVEELKR-
MAV_1744|M.avium_104 FETEAEVVELGVRSAPRAVAEALGRSGELLHIVRVRRQRRTREPLMVTDA
Mb0601|M.bovis_AF2122/97 --LRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTL
Rv0586|M.tuberculosis_H37Rv --LRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTL
Mflv_4061|M.gilvum_PYR-GCK --LTDVRGAD-PADYRRLDSRLHLAIAEAAGVPSLVPLVAQNRMRLNELL
Mvan_2282|M.vanbaalenii_PYR-1 --LLDVRGAA-PQDYRRLDSRLHLAITEAAGVPSLVPLVAQNRMRLNEML
MSMEG_2599|M.smegmatis_MC2_155 --LADVRAAEGTDDYRRLDSRLHLAIAEAAGSPSLVPLIAENRMRINGLL
MAB_4644c|M.abscessus_ATCC_199 ---AKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAM
MMAR_0749|M.marinum_M LWSREPANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAV
MUL_1381|M.ulcerans_Agy99 LWSREPANDKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAV
TH_4115|M.thermoresistible__bu --TAAMVDPADQEAAMQQSADFHSAILRASGNKLLEAMGRPVSAVARSKF
MAV_1744|M.avium_104 WLPPELAPVLTERALRRAPLYELLSANGVAVDRVRHEITAEIAGPRNAQL
: . .
Mb0601|M.bovis_AF2122/97 AALTTTMTAAAK------RPSDYRKLADAICSGDPTGAKKAAQDLLELAN
Rv0586|M.tuberculosis_H37Rv AALTTTMTAAAK------RPSDYRKLADAICSGDPTGAKKAAQDLLELAN
Mflv_4061|M.gilvum_PYR-GCK DRIPLMTRNIAH------SDEQHEAIVSAILAGDADTAAQTMAAHVWGSA
Mvan_2282|M.vanbaalenii_PYR-1 DCIPLLPRNIAH------SDEQHEAIVMAILAGDADGAAQTMAAHVWGSA
MSMEG_2599|M.smegmatis_MC2_155 DRIPLLPRNIAH------SDDQHEAIVMAILAGDADRAATAMLDHVSGSA
MAB_4644c|M.abscessus_ATCC_199 LALLAGSAERPH------DQEHHQWLFDAIVDGSTRRAVELATDQLQHVR
MMAR_0749|M.marinum_M EAGPVGTCTS--------YEREHTELVEAIIAGDPQRAEAAAQVFIARLR
MUL_1381|M.ulcerans_Agy99 EAGPVGTCTS--------YEREHTELVEAIIAGDPQRAEAAAQVFIARLR
TH_4115|M.thermoresistible__bu RRTVPGLEFWER------NQRAHQELLKAILAGDENLAYELATRHIDEDL
MAV_1744|M.avium_104 LDVPIGAALLRVNRLVYVGDRPHHHVSALLSPSRSRVLLSQSADDMETGD
: : : . :
Mb0601|M.bovis_AF2122/97 TSLMAVLVSQASRQ---
Rv0586|M.tuberculosis_H37Rv TSLMAVLVSQASRQ---
Mflv_4061|M.gilvum_PYR-GCK ALLHGFLD---------
Mvan_2282|M.vanbaalenii_PYR-1 ALLHGFLD---------
MSMEG_2599|M.smegmatis_MC2_155 ALLHGFLD---------
MAB_4644c|M.abscessus_ATCC_199 MR---------------
MMAR_0749|M.marinum_M P----------------
MUL_1381|M.ulcerans_Agy99 R----------------
TH_4115|M.thermoresistible__bu SPYYLPPEEADRDGAGA
MAV_1744|M.avium_104 GLRIAHDVGGPRG----