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QTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGTARNTVREAVQALVHVGILERRQGSGTY VIADVEQGSALAEYFAAARERDLWELREAVEVTAAVLSARRRDAADIEDLRALLARRNELWSREPANDKE RTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAVEAGPVGTCTSYEREHTELVEAIIAGDPQRAE AAAQVFIARLRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0749 | - | - | 100% (223) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0820 | - | 3e-14 | 27.83% (230) | GntR family transcriptional regulator |
| M. marinum M | MMAR_1630 | - | 2e-10 | 25.00% (232) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 2e-11 | 27.78% (234) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 2e-37 | 42.41% (224) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0586 | - | 2e-11 | 27.78% (234) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2272c | - | 4e-70 | 59.91% (222) | putative transcriptional regulator, GntR |
| M. avium 104 | MAV_3932 | - | 5e-13 | 27.80% (223) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_2794 | - | 6e-36 | 42.08% (221) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4115 | - | 1e-14 | 31.13% (212) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1381 | - | 1e-120 | 99.09% (219) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0952 | - | 2e-32 | 39.29% (224) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0749|M.marinum_M ----------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MUL_1381|M.ulcerans_Agy99 -------------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCE
MAB_2272c|M.abscessus_ATCC_199 ----------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCE
Mflv_0016|M.gilvum_PYR-GCK MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDRIPNETVLVE
Mvan_0952|M.vanbaalenii_PYR-1 --------MPLSTARRTGLVDQVIEQLRRAVAGGEWRVGERIPNETVLVE
MSMEG_2794|M.smegmatis_MC2_155 --------MPLASTRRTGLVDQVIEQLRASVSSGEWPVGTKIPTEPELAD
Mb0601|M.bovis_AF2122/97 --------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAE
Rv0586|M.tuberculosis_H37Rv --------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEALPSERRLAE
MAV_3932|M.avium_104 ------MNAEPRTGPAKTLASALARDIEAEIVRRGWAVGESLGSEPALQQ
TH_4115|M.thermoresistible__bu ---------------VQSSYIQVADQLRDLILRGDLAVGQKLPSEAEMAP
: :: : * : .* :
MMAR_0749|M.marinum_M MTGTARNTVREAVQALVHVGILERRQG--SGTYVIADVEQGS--------
MUL_1381|M.ulcerans_Agy99 MTGTARNTVREAVQALVHVGILERRQG--SGTYVIADVEQGS--------
MAB_2272c|M.abscessus_ATCC_199 LTGTSRNTIREAVQALVHAGMLERRQG--SGTYVLS-LGGSS--------
Mflv_0016|M.gilvum_PYR-GCK KFGVGRNTVREAVRALAHAGILEVRQG--DGTYVRATSEVSG--------
Mvan_0952|M.vanbaalenii_PYR-1 SLGVGRNTVREAVRALAHAGILEVRQG--DGTYVRATSEVSG--------
MSMEG_2794|M.smegmatis_MC2_155 TLGVGRNTLREAVRALAHSGILEVRQG--DGTYVRATSEVSG--------
Mb0601|M.bovis_AF2122/97 LLGVSRPAVREALKRLSAAGLVEVRQG--DVTTVRDFRRHAGL------D
Rv0586|M.tuberculosis_H37Rv LLGVSRPAVREALKRLSAAGLVEVRQG--DVTTVRDFRRHAGL------D
MAV_3932|M.avium_104 RFGVSRSVLREAVRLVEHHQVARMRRGPNGGLYICEPDAGPAT----RAV
TH_4115|M.thermoresistible__bu LLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERLEGMFNTSF
*..* .:***:: : : . *:* . :
MMAR_0749|M.marinum_M ALAEYFAAARERDLWELREAVEVTAAVLSARRRDAADIEDLRALLARRNE
MUL_1381|M.ulcerans_Agy99 ALAEYFAAARERDLWELREAVEVTAAVLSARRRDAADIEDLRVLLARRNE
MAB_2272c|M.abscessus_ATCC_199 AIADYFAAANNRDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNE
Mflv_0016|M.gilvum_PYR-GCK ALRR-LCGEELREVLEVRRALEVEAARLAASRRTPADVAEMRGLLARRD-
Mvan_0952|M.vanbaalenii_PYR-1 ALRR-LCGAELREVLQVRRALEVEGARLAAAHCTPADIAEMRTLLARRD-
MSMEG_2794|M.smegmatis_MC2_155 ALRR-LCGSELREVLQVRRCLEVEGARLAASNRTDADLAELRAFLDR---
Mb0601|M.bovis_AF2122/97 LLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDS
Rv0586|M.tuberculosis_H37Rv LLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQDS
MAV_3932|M.avium_104 VIYLEYLGTTLADLLNARLVLEPLAASLAAERIDEAGIARLRAVLHAEQQ
TH_4115|M.thermoresistible__bu SMLALTNQVDARSFLQAMRALEGPAAALAAAARGGDQVEELKRTAAMVDP
: .. :* :. .
MMAR_0749|M.marinum_M LWSREPANDKERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAV
MUL_1381|M.ulcerans_Agy99 LWSREPANDKERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAV
MAB_2272c|M.abscessus_ATCC_199 LWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYM
Mflv_0016|M.gilvum_PYR-GCK ----ERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTASV
Mvan_0952|M.vanbaalenii_PYR-1 ----ECAATDDTDAFARTDAEFHLAVVRGSGNRTLTELYRGLIEVVTASV
MSMEG_2794|M.smegmatis_MC2_155 ------TETSDDDDFVHSDTAFHLAVVRASHNSVLIELYRGLIEAITASV
Mb0601|M.bovis_AF2122/97 LR--ALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTL
Rv0586|M.tuberculosis_H37Rv LR--ALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTL
MAV_3932|M.avium_104 WR----------PGLPMPRDEFHIALAEQSKNPVLQLFIKVLMRLTTRYA
TH_4115|M.thermoresistible__bu ---------ADQEAAMQQSADFHSAILRASGNKLLEAMGRPVSAVARSKF
. : : . : .
MMAR_0749|M.marinum_M E-------AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRP
MUL_1381|M.ulcerans_Agy99 E-------AGPVGTCTSYEREHTELVEAIIAGDPQRAEAAAQVFIARLRR
MAB_2272c|M.abscessus_ATCC_199 R-------GNPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAELRL
Mflv_0016|M.gilvum_PYR-GCK A-------HTRHVPVD--VCDHGVLLDHIAAGDPDLAARTAGEFLDRIIN
Mvan_0952|M.vanbaalenii_PYR-1 A-------TTRHVPVE--MVDHGVLVDQIAAGDAEQAARTAGELLDRILA
MSMEG_2794|M.smegmatis_MC2_155 A-------TASARPDG--KVSHRGLVEAIAAGDVERAGREAGGFLDDLLA
Mb0601|M.bovis_AF2122/97 AAL-----TTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANT
Rv0586|M.tuberculosis_H37Rv AAL-----TTTMTAAAKRPSDYRKLADAICSGDPTGAKKAAQDLLELANT
MAV_3932|M.avium_104 LQSRTDSETEALEAVDHLHTHHSRIVAAVTAGDPARAKTLSERHVEAVTA
TH_4115|M.thermoresistible__bu RRT-----VPGLEFWERNQRAHQELLKAILAGDENLAYELATRHIDEDLS
: : : :** * : .
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 SRDQPGRNFPHHPHD-----------------------------------
Mflv_0016|M.gilvum_PYR-GCK GLGSADSS------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 GVDSADSC------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 QTPDPQG-------------------------------------------
Mb0601|M.bovis_AF2122/97 SLMAVLVSQASRQ-------------------------------------
Rv0586|M.tuberculosis_H37Rv SLMAVLVSQASRQ-------------------------------------
MAV_3932|M.avium_104 WLQRHHAGDRNRGRTPRRPLNSEVPQGKLAEMLAATIGDDIAADGWRVGS
TH_4115|M.thermoresistible__bu PYYLPPEEADRDGAGA----------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 --------------------------------------------------
Rv0586|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3932|M.avium_104 VFGTETALLQRYRVSRAVFREAVRLLEYHSIAHMRRGPGGGLVIAEPAAQ
TH_4115|M.thermoresistible__bu --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 --------------------------------------------------
Rv0586|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3932|M.avium_104 ASIDTIALYLQYRDPSREDLRCVRDAIEIDNVAKVVKRLAEPQVAAFVAS
TH_4115|M.thermoresistible__bu --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 --------------------------------------------------
Rv0586|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3932|M.avium_104 RRSGLPDDSRQTPDDVRRAIAEEFDFHVGLAQLAGNAPLDLFLRIIVELF
TH_4115|M.thermoresistible__bu --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0016|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2794|M.smegmatis_MC2_155 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 --------------------------------------------------
Rv0586|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3932|M.avium_104 RRHWSSTGQALPTWSDVRAVHHAHLRIADAVAAGDLSVASYRLRRHLDAA
TH_4115|M.thermoresistible__bu --------------------------------------------------
MMAR_0749|M.marinum_M -----
MUL_1381|M.ulcerans_Agy99 -----
MAB_2272c|M.abscessus_ATCC_199 -----
Mflv_0016|M.gilvum_PYR-GCK -----
Mvan_0952|M.vanbaalenii_PYR-1 -----
MSMEG_2794|M.smegmatis_MC2_155 -----
Mb0601|M.bovis_AF2122/97 -----
Rv0586|M.tuberculosis_H37Rv -----
MAV_3932|M.avium_104 ASWWL
TH_4115|M.thermoresistible__bu -----