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VKRSARATPGPRDDRGVLAARILAAARETFAESGWAGTTIRAVARAADVDPALVYHYYGSKEGLLDAATD PPQKWLDAVVATWQAPVGDTGRAVLRLLLDSWADDEVGPVLRAILQTAAHEPTTHEKLRKVVERSLIGVI ATMGDDERVRRTRAGLVASQTIGFALMRYVWRIEPVASMREDEVLDAVGPTLQRYIDGDIGAAGQIRTGF DTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5282 | - | - | 100% (214) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3765 | - | 4e-28 | 36.71% (207) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1700 | - | 7e-23 | 36.16% (177) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 9e-24 | 34.98% (203) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-22 | 32.81% (192) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 9e-24 | 34.98% (203) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 5e-05 | 37.50% (56) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2351c | - | 1e-19 | 32.46% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4115 | - | 9e-73 | 66.67% (195) | putative regulatory protein |
| M. avium 104 | MAV_3088 | - | 4e-25 | 39.13% (184) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3542 | - | 2e-26 | 33.16% (187) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3981 | - | 1e-72 | 66.67% (195) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2569 | - | 1e-74 | 68.02% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4115|M.marinum_M ---MGGRRVKPGPRDEKGVLAAQILSVARDSFAENGSAGTTVRSVARAAD
MUL_3981|M.ulcerans_Agy99 ---MGGRRVKPGPRDEKGVLAAQILSVARDSFAENGSAGTTVRSVARAAD
Mvan_2569|M.vanbaalenii_PYR-1 ---MS--KIPPGPRDERGVLSSRILVAARGAFADTGYAGTTIRAVARAAD
MSMEG_5282|M.smegmatis_MC2_155 -MVKRSARATPGPRDDRGVLAARILAAARETFAESGWAGTTIRAVARAAD
Mb1711c|M.bovis_AF2122/97 MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
Rv1685c|M.tuberculosis_H37Rv MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAG
MAV_3088|M.avium_104 MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTSIRAVAAAAG
MAB_2351c|M.abscessus_ATCC_199 MSS-----KRPGRRPGTSSARDDILASARKLFSLNGIDKTSIRAIASDAG
Mflv_0253|M.gilvum_PYR-GCK MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTTLRAIAEDAG
TH_3542|M.thermoresistible__bu -----------------------VLAAAKRRFAQDGYEKTTLRAIARDAH
MLBr_02568|M.leprae_Br4923 -------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEAQ
:* * *: * *:: ::* *
MMAR_4115|M.marinum_M VDPSLIYHYFGSKEGLLDAATTPPQRWLDTVAETWTTPKADLGRRLLQTL
MUL_3981|M.ulcerans_Agy99 VDPSLIYHYFGSKEGLLDAATMPPQRWLDTVAETWTTPKADLGRRLLQTL
Mvan_2569|M.vanbaalenii_PYR-1 VDPALVYHYFGSKEALLDAATDPPQRWLQNVARAWTTPVPQLGAALVRLM
MSMEG_5282|M.smegmatis_MC2_155 VDPALVYHYYGSKEGLLDAATDPPQKWLDAVVATWQAPVGDTGRAVLRLL
Mb1711c|M.bovis_AF2122/97 VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
Rv1685c|M.tuberculosis_H37Rv VDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAPVEELGYKLPSLL
MAV_3088|M.avium_104 VDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVPVDDLGYALPSML
MAB_2351c|M.abscessus_ATCC_199 VDPALVHHYFGTKLDLFREVVQLPVDPSVVLQPLRDVPVDELGVTIPRLI
Mflv_0253|M.gilvum_PYR-GCK VDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGG-EADIGTRMVRAY
TH_3542|M.thermoresistible__bu VDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGD-DGDVGTRMVRVY
MLBr_02568|M.leprae_Br4923 ISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDLLRNTI
:. .:: :*:* *: : . :
MMAR_4115|M.marinum_M LDSWADDEIGPSLRAILLTAAHEDATRLKLRRIVESSLIG-VSQLDTD-E
MUL_3981|M.ulcerans_Agy99 LDSWADDEIGPSLRAILLTAAHEDATRLKLRRIVESSLIG-VSQLDTD-E
Mvan_2569|M.vanbaalenii_PYR-1 LDAWADEEIGPVLRAILQTAAHEAATREKLRLVVERSLMG-VSQLGVD-E
MSMEG_5282|M.smegmatis_MC2_155 LDSWADDEVGPVLRAILQTAAHEPTTHEKLRKVVERSLIGVIATMGDD-E
Mb1711c|M.bovis_AF2122/97 LPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVDNPP
Rv1685c|M.tuberculosis_H37Rv LPIWDS-ELGAGLIATLRSLISGSDV-GLARSFLEEVVTVELGSRVDNPP
MAV_3088|M.avium_104 LPLWDS-EVGAAFIATLRSILAGEEI-SLFRTFIQDVIGVEVGPRVDNPA
MAB_2351c|M.abscessus_ATCC_199 IALWDS-ELGANMLAVFRSALTGADD-GLVRVFFREVLVNIIAERVDSPP
Mflv_0253|M.gilvum_PYR-GCK LGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVLAAVVGTLGG-D
TH_3542|M.thermoresistible__bu LQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLLTAVSGVLGG-G
MLBr_02568|M.leprae_Br4923 VSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAGLMRVGT
: : : . : :
MMAR_4115|M.marinum_M DDRLTRSGLIASQLIGLAMTRYVWQIEPIASMSDSEVLAAITPNLQRYID
MUL_3981|M.ulcerans_Agy99 DDRLTRSGLIASQLIGLAMTRYVWQIEPIASMSDSEVLAAITPNLQRYID
Mvan_2569|M.vanbaalenii_PYR-1 RDRMLRSGLISSQIMGLAMMRYVWRIEPVASMDDDELVAAVAPNLQRYIS
MSMEG_5282|M.smegmatis_MC2_155 RVRRTRAGLVASQTIGFALMRYVWRIEPVASMREDEVLDAVGPTLQRYID
Mb1711c|M.bovis_AF2122/97 GTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLT
Rv1685c|M.tuberculosis_H37Rv GTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLT
MAV_3088|M.avium_104 GSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAATIAPNLQRYLT
MAB_2351c|M.abscessus_ATCC_199 GSGVLRAEFAITQMAGILVGRYIMAIEPLASLTAEQIALTVGPNIQRYLT
Mflv_0253|M.gilvum_PYR-GCK DRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIRLVAPTVTRYLT
TH_3542|M.thermoresistible__bu EQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVRMLAPTVNRYLT
MLBr_02568|M.leprae_Br4923 RSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELMINLFWHGLK
. : . ..: .: : . : :
MMAR_4115|M.marinum_M GDLHPTKKSPAQRPRRTRRP
MUL_3981|M.ulcerans_Agy99 GDLHPTKNSPAQRPRRTRRP
Mvan_2569|M.vanbaalenii_PYR-1 DDLG----------------
MSMEG_5282|M.smegmatis_MC2_155 GDIGAAGQIRTGFDTA----
Mb1711c|M.bovis_AF2122/97 GELPDDLAP-----------
Rv1685c|M.tuberculosis_H37Rv GELPDDLAP-----------
MAV_3088|M.avium_104 GDLPDGLAP-----------
MAB_2351c|M.abscessus_ATCC_199 GALPS-ITP-----------
Mflv_0253|M.gilvum_PYR-GCK APADELGLPG----------
TH_3542|M.thermoresistible__bu ADADELGLPSSLTAGS----
MLBr_02568|M.leprae_Br4923 GAPADRDFGPSIVAG-----