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PGQVGMSAHRAGRPFFARAVRVLALPIVAFWILVTIGTNIFVPQAEKVADELAGPMIPTYAPSQVALLQM GEKFGESDSTNLTMLVLEADRPLDDADHRFYDDLVRRLQSDPAHVQYVMDLWGEPITAAAVQSVDGKAAF VMLRLAGNTGKLEANESVDAVRDIVAADAPPPGLKVYVSGPAPLASDTLTIATASLKNITILTIILIVAM LLLVYRSVPSLLVPLPAVLIELLAAKGVVAVLGHLGVIPLSSFAVNLLVALTLGAGTDYGIFMLGRYQEA RRAGESREEAYFTAYRSVAPIIIGSGLTIAGACFCLSLARLDYFHTMGPAVAVSMLCTIAAALTLAPALL TLGSRRGLFDPRRLNSGRLYRHIATSVVRWPKPVFVASAVVVLVGAVFVPTYQVGYDDRAYQPADAPAKL GFEAADRHFPQSKLMSELLMVESDHDMRNSADFISLDRAAKSLIRLPGVAMVQSITRPLGRPLEHATIPY LFTMQGSTSGQQLPFDQQLNENTDRQADIQAHSLQVIQQVISITTQMSDELHATTVTFENLKEVTDEVNE GISDLDDFLRPLKNYFYWEPHCFDIPVCFAIRSLFDSLDGIDRLDEQIGNAVESFEAIDRLLPQMITQLE QMKIAGKATLSLLQNNYGSAHLQSTQTDQTYDDLINVGNDFDAARSDDFFYIPHEAFDNDDVKTGMKLLM SPDGKAARFIITHEGNAMAQEGIEHVEQIPDAIKMALKETSLAGAKVYLGGAASSTKDIQDYAASDLLIV AIAAFVLIFLIMLYLTRSLVAAMVIPGTVAFSFAGAFGLSVLVWQHLIGLPLHWLVLPLAFIILVAVGSD YNLLLISRVKEESGAGLNTALIRALGSTGAVVTSAGLVFAFTMLSMLASNLAAVGQLGSTVCIGLLLDTM IVRSLVVPCLLRLLGPWFWWPTFIRQRPLRTPDRFARPGPSRRIMTDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3584 | - | - | 100% (959) | membrane protein, MmpL family protein |
| M. smegmatis MC2 155 | MSMEG_0185 | - | 0.0 | 84.59% (941) | MmpL6 protein |
| M. smegmatis MC2 155 | MSMEG_3496 | - | 0.0 | 46.65% (941) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 48.94% (944) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_3029 | - | 0.0 | 47.62% (947) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 49.05% (944) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 47.20% (928) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_4768c | - | 0.0 | 71.11% (938) | putative membrane protein, MmpL |
| M. marinum M | MMAR_3744 | mmpL4_1 | 0.0 | 48.62% (940) | transmembrane transport protein MmpL4_1 |
| M. avium 104 | MAV_1755 | - | 0.0 | 47.21% (951) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 45.68% (950) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 48.83% (944) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 49.73% (929) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3744|M.marinum_M MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MUL_3688|M.ulcerans_Agy99 MSESN--SGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILAVP
MAV_1755|M.avium_104 MSDASNKTQPDLSAADTGPINVKGLS----KAERGHRPYLPHAIRIFAVP
Mb0458c|M.bovis_AF2122/97 ----------MSTKFANDSNTN----------ARPEKPFIARMIHAFAVP
Rv0450c|M.tuberculosis_H37Rv ----------MSTKFANDSNTN----------ARPEKPFIARMIHAFAVP
MLBr_02378|M.leprae_Br4923 ----------MTVKCANDLDTH----------TKP--PFVARMIHRFAVP
Mflv_3029|M.gilvum_PYR-GCK MTT-----HIDDSVTADLPPAH----------KPHR-SRLARFIRTFAIP
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKV----------STHGPSFISTWIRRLSLP
Mvan_1936|M.vanbaalenii_PYR-1 ---------------------M----------ADAGRSGIGRIIHLLAVP
MSMEG_3584|M.smegmatis_MC2_155 --------MPGQVGMSA---------------HRAGRPFFARAVRVLALP
MAB_4768c|M.abscessus_ATCC_199 -----------MSEQSK---------------HSVKRPLIPRMVRVLAVP
. . :: :::*
MMAR_3744|M.marinum_M IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MUL_3688|M.ulcerans_Agy99 IILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNFRE
MAV_1755|M.avium_104 IILGWLFVTVLVNVIVPTLEKVGEAHSAPMTPLDAPSMKAMMRLGHNFHE
Mb0458c|M.bovis_AF2122/97 IILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKE
Rv0450c|M.tuberculosis_H37Rv IILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKE
MLBr_02378|M.leprae_Br4923 IILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNE
Mflv_3029|M.gilvum_PYR-GCK IVLAWIAIVAILNVSVPQLEDVGKMRAVSMSPDDAPALIATKRVGAVFEE
TH_3260|M.thermoresistible__bu IIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDE
Mvan_1936|M.vanbaalenii_PYR-1 IVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANFDE
MSMEG_3584|M.smegmatis_MC2_155 IVAFWILVTIGTNIFVPQAEKVADELAGPMIPTYAPSQVALLQMGEKFGE
MAB_4768c|M.abscessus_ATCC_199 IVVFWAIVAVTTNTFVPHVEDVAEELAGPMIPHYAPSQRAMLHIGEKFQE
*: * : . :* * *.. : : . **: : ::* * *
MMAR_3744|M.marinum_M FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MUL_3688|M.ulcerans_Agy99 FDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGDRL
MAV_1755|M.avium_104 FDSNSTVMIVLEGQQPLGPDAHKYYDNLIRQLRQDPKHIQHIQDFWGDRL
Mb0458c|M.bovis_AF2122/97 GDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPL
Rv0450c|M.tuberculosis_H37Rv GDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPL
MLBr_02378|M.leprae_Br4923 GNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPL
Mflv_3029|M.gilvum_PYR-GCK YTTSSSVMIVLEGDEPLGADAHTFYDEIVRQLRADAAHVQHVQDFWGDPL
TH_3260|M.thermoresistible__bu GSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPL
Mvan_1936|M.vanbaalenii_PYR-1 FDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGDPL
MSMEG_3584|M.smegmatis_MC2_155 SDSTNLTMLVLEADRPLDDADHRFYDDLVRRLQSDPAHVQYVMDLWGEPI
MAB_4768c|M.abscessus_ATCC_199 STSTSLTMLVLEADRPLDGSDHQYYDDLVRRLKSDTEHVQYVMDTWGKPI
: . *:::*.:. *. : :** :: :*. * ::: : * *.. :
MMAR_3744|M.marinum_M TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTHE---PAG
MUL_3688|M.ulcerans_Agy99 TAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRTHE---PAG
MAV_1755|M.avium_104 TAAGAQSADAKGAYVQVNLAGNQGTTLANESVDAVRKVIDENKA---PPG
Mb0458c|M.bovis_AF2122/97 TAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---PPG
Rv0450c|M.tuberculosis_H37Rv TAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTPA---PPG
MLBr_02378|M.leprae_Br4923 TAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTPA---PPG
Mflv_3029|M.gilvum_PYR-GCK TSSGAQSMDGKAAYVQVYIAGDQGESLANESVQAVRDIIAGIEP---PAG
TH_3260|M.thermoresistible__bu TATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEG
Mvan_1936|M.vanbaalenii_PYR-1 TASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTPA---PPG
MSMEG_3584|M.smegmatis_MC2_155 TAAAVQSVDGKAAFVMLRLAGNTGKLEANESVDAVRDIVAADAP---PPG
MAB_4768c|M.abscessus_ATCC_199 TAAGAQSLDGKSAFVLLRLAGDIGQTQANKSVEAIKETIDKDTP---PRG
*:...** *.*.*:* : : *: * *:::: :::. : * *
MMAR_3744|M.marinum_M VKAYVTGPAALSDDMHLIGNASLAKITMFTLGAIAVMLLLVYRSIVTTVI
MUL_3688|M.ulcerans_Agy99 VKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTTVI
MAV_1755|M.avium_104 VKAYVTGPAALSDDMHIIGNASLAKITLFTLGAIAIMLLLVYRSIVTTLV
Mb0458c|M.bovis_AF2122/97 IKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVL
Rv0450c|M.tuberculosis_H37Rv IKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVL
MLBr_02378|M.leprae_Br4923 ITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVIL
Mflv_3029|M.gilvum_PYR-GCK VQAYVTGPAASTADQRVVGDASMRTIEALTFAVIITMLLLVYRSIVTVLI
TH_3260|M.thermoresistible__bu VQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLI
Mvan_1936|M.vanbaalenii_PYR-1 LKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATMVL
MSMEG_3584|M.smegmatis_MC2_155 LKVYVSGPAPLASDTLTIATASLKNITILTIILIVAMLLLVYRSVPSLLV
MAB_4768c|M.abscessus_ATCC_199 LKVYVSGAAPLASDTLSVANSSLNNITIVTIFLIIFMLLMVYRSVTTMLV
: .:*:* :. * . *: : :. * **:*:**. : ::
MMAR_3744|M.marinum_M QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MUL_3688|M.ulcerans_Agy99 QLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGIFL
MAV_1755|M.avium_104 QLFMTFVALACSRGVVAVLAYHNAFGLTTFAANILTMLAIAAGTDYGIFL
Mb0458c|M.bovis_AF2122/97 LLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFI
Rv0450c|M.tuberculosis_H37Rv LLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFI
MLBr_02378|M.leprae_Br4923 LLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFI
Mflv_3029|M.gilvum_PYR-GCK TMGMVVIGLLSARGSVAFLGYHEVFGLTTFATNLLVTLAIAAATDYAIFL
TH_3260|M.thermoresistible__bu ALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFL
Mvan_1936|M.vanbaalenii_PYR-1 ILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAIFA
MSMEG_3584|M.smegmatis_MC2_155 PLPAVLIELLAAKGVVAVLGHLGVIPLSSFAVNLLVALTLGAGTDYGIFM
MAB_4768c|M.abscessus_ATCC_199 PLFGVLVEMLVARGVVATLGHFGYIELSSFAVNIVIALTLGAGTDYGIFL
: . ::* ** *. : *::**..:: :.:. ..**.**
MMAR_3744|M.marinum_M VGRYQEARQAGEDREDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MUL_3688|M.ulcerans_Agy99 VGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARLPW
MAV_1755|M.avium_104 IGRYQEALAAGEDRESAYYTTFKGVAPVVLGSGLTIAGATYCLSFSRLPW
Mb0458c|M.bovis_AF2122/97 IGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPY
Rv0450c|M.tuberculosis_H37Rv IGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPY
MLBr_02378|M.leprae_Br4923 TGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPY
Mflv_3029|M.gilvum_PYR-GCK IGRYQEARRAGEDRESAYYTMFHGTAHVVLASGLTIAGAAACLHFTRLPY
TH_3260|M.thermoresistible__bu IGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPY
Mvan_1936|M.vanbaalenii_PYR-1 IGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRLPY
MSMEG_3584|M.smegmatis_MC2_155 LGRYQEARRAGESREEAYFTAYRSVAPIIIGSGLTIAGACFCLSLARLDY
MAB_4768c|M.abscessus_ATCC_199 LGRYHEARNAGLDREDAFYSAYRGVSHVIIGSGLTIAGAGLCLSFARLNY
***:** .. .: *:.: : .. :::.*****:** ** ::*: :
MMAR_3744|M.marinum_M FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHLFESKRAANRGRLWRR
MUL_3688|M.ulcerans_Agy99 FNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLWRR
MAV_1755|M.avium_104 FNTMGAPVAIGMLVVVLAGVTLGPAVVFVGSRFHFFE--RQAKRGRLWRR
Mb0458c|M.bovis_AF2122/97 FQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRR
Rv0450c|M.tuberculosis_H37Rv FQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRR
MLBr_02378|M.leprae_Br4923 FQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRR
Mflv_3029|M.gilvum_PYR-GCK FNTMGFPLSIGMVVVVAAALTLGPAVISIVTRFGRVLEPKGMKRARGWRR
TH_3260|M.thermoresistible__bu FQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRK
Mvan_1936|M.vanbaalenii_PYR-1 FQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGWRR
MSMEG_3584|M.smegmatis_MC2_155 FHTMGPAVAVSMLCTIAAALTLAPALLTLGSRRG-LFDPRRLNSGRLYRH
MAB_4768c|M.abscessus_ATCC_199 FHTMGPAVAIAMLLTIAAALTLGPALLHLGSLFG-LFDPKRRVKARLYRR
*:::* . ::. . : ..:*:.**:: : : . : * :*:
MMAR_3744|M.marinum_M VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MUL_3688|M.ulcerans_Agy99 VGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNLGE
MAV_1755|M.avium_104 VGTAVVRWPAPVLAVSAAVVLVGMIALPSFHTSYNDRHYLPLSAPSNQGQ
Mb0458c|M.bovis_AF2122/97 VGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGY
Rv0450c|M.tuberculosis_H37Rv VGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGY
MLBr_02378|M.leprae_Br4923 IGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGF
Mflv_3029|M.gilvum_PYR-GCK IGAATVRWPGAVLVMAVVLALVGLLTLPGYHTTYNDRIFQPPDVPANVGY
TH_3260|M.thermoresistible__bu VGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGY
Mvan_1936|M.vanbaalenii_PYR-1 IGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANVGY
MSMEG_3584|M.smegmatis_MC2_155 IATSVVRWPKPVFVASAVVVLVGAVFVPTYQVGYDDRAYQPADAPAKLGF
MAB_4768c|M.abscessus_ATCC_199 IGASVVRWPKPILVASAAAVLVGAVFVPTYQVNYDDRAYQPPDAPAKQGF
:.. .**** .:: : . .:** : :* ::. *..* : * *:: *
MMAR_3744|M.marinum_M AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MUL_3688|M.ulcerans_Agy99 AAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGIAMI
MAV_1755|M.avium_104 EAANRHFSEARMNPDLLMIESDHDMRNPADMLVLDRVAKNEMRTLGIAMV
Mb0458c|M.bovis_AF2122/97 AAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
Rv0450c|M.tuberculosis_H37Rv AAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRV
MLBr_02378|M.leprae_Br4923 AAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRV
Mflv_3029|M.gilvum_PYR-GCK AAANRHFSEAKMNPELVMVEADHDLRNPADFLVIDKIAKAMARVHGIAQV
TH_3260|M.thermoresistible__bu EAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRV
Mvan_1936|M.vanbaalenii_PYR-1 AVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVARV
MSMEG_3584|M.smegmatis_MC2_155 EAADRHFPQSKLMSELLMVESDHDMRNSADFISLDRAAKSLIRLPGVAMV
MAB_4768c|M.abscessus_ATCC_199 AAADRHFPPSKLFTEMLMVESDHDMRNSADFISLDRVSKSLVRLPGVAMV
.*:*** ::: .:::::*::**:**.**:: ::: :: : *:: :
MMAR_3744|M.marinum_M QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MUL_3688|M.ulcerans_Agy99 QDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADEMQV
MAV_1755|M.avium_104 QDITRPLGIPIQHSSIPFQNSVQSQTTMQNMGFLKERMNDILKMADDLQT
Mb0458c|M.bovis_AF2122/97 QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
Rv0450c|M.tuberculosis_H37Rv QAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMAT
MLBr_02378|M.leprae_Br4923 QAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAE
Mflv_3029|M.gilvum_PYR-GCK QAITRPDGKPIEHASLPYVVSQSGTGQIMSNDYQQKVLENTLKQADDLQV
TH_3260|M.thermoresistible__bu QGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQL
Mvan_1936|M.vanbaalenii_PYR-1 QTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAMQT
MSMEG_3584|M.smegmatis_MC2_155 QSITRPLGRPLEHATIPYLFTMQGSTSGQQLPFDQQLNENTDRQADIQAH
MAB_4768c|M.abscessus_ATCC_199 QSITRPMGRALEHASLPYLFTTQGSGNGQQLPFTKAQNANTDRQAQIMAH
* **** * .:.*:::*: : . : : : *:
MMAR_3744|M.marinum_M LIDTTERMYAVMRDLDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MUL_3688|M.ulcerans_Agy99 LIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFWRPM
MAV_1755|M.avium_104 QIDTTQRQYEVSMDLANAADDSAKTTAVTSQITDSLRDHIADFDDTFRPI
Mb0458c|M.bovis_AF2122/97 TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
Rv0450c|M.tuberculosis_H37Rv TIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPI
MLBr_02378|M.leprae_Br4923 TIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPI
Mflv_3029|M.gilvum_PYR-GCK SIDTMKRMHSLTLQMADVSRRMADKMRTTSEHTSEVRDHLADFDDFFRPI
TH_3260|M.thermoresistible__bu MIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPI
Mvan_1936|M.vanbaalenii_PYR-1 NVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVRPV
MSMEG_3584|M.smegmatis_MC2_155 SLQVIQQVISITTQMSDELHATTVTFENLKEVTDEVNEGISDLDDFLRPL
MAB_4768c|M.abscessus_ATCC_199 SVAVLRQTTDLTQQLADEMHNTVVTMEDMQQVTQDMNEKVSNLDDFMRPL
: : : : .:.: ::::** **:
MMAR_3744|M.marinum_M RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQHTAGLT
MUL_3688|M.ulcerans_Agy99 RSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTAGLT
MAV_1755|M.avium_104 RTYFYWEKHCYDIPVCIGLRSLFDTFDGFDQLAEQFHYLTTDIAHTAKAS
Mb0458c|M.bovis_AF2122/97 RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
Rv0450c|M.tuberculosis_H37Rv RSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLM
MLBr_02378|M.leprae_Br4923 RSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLM
Mflv_3029|M.gilvum_PYR-GCK RNYFYWEPHCFNIPICWALRSVFDSLDGINTLSDDLEDVVPDIEELATLT
TH_3260|M.thermoresistible__bu RNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLM
Mvan_1936|M.vanbaalenii_PYR-1 RNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDALM
MSMEG_3584|M.smegmatis_MC2_155 KNYFYWEPHCFDIPVCFAIRSLFDSLDGIDRLDEQIGNAVESFEAIDRLL
MAB_4768c|M.abscessus_ATCC_199 RNYFYWEPHCFDIPVCQSFRSLFDMLDSIDKLAADIKDAVGSLEVVDRLL
:.***** **:.:*:* :**:** :*..: : : :
MMAR_3744|M.marinum_M SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MUL_3688|M.ulcerans_Agy99 SQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQSFD
MAV_1755|M.avium_104 RDLTALFPTLITTLKTTRGITLTLYQTFKAMIDQMEAMSNTAVVMGQSFD
Mb0458c|M.bovis_AF2122/97 PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
Rv0450c|M.tuberculosis_H37Rv PQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFD
MLBr_02378|M.leprae_Br4923 PQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFD
Mflv_3029|M.gilvum_PYR-GCK PQLAALLPAQIQTLQNQKQLLLNQYQAQKAQQDHTMAAQENATAMGEAFD
TH_3260|M.thermoresistible__bu PQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFD
Mvan_1936|M.vanbaalenii_PYR-1 PQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEAFD
MSMEG_3584|M.smegmatis_MC2_155 PQMITQLEQMKIAGKATLSLLQNNYGSAHLQSTQTDQTYDDLINVGNDFD
MAB_4768c|M.abscessus_ATCC_199 PQMVALLKLTANDQEALQALIVNTYGQTNLQATATDQTFDDMINVGNDFD
:: : . : . : :*: **
MMAR_3744|M.marinum_M ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MUL_3688|M.ulcerans_Agy99 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMTPEG
MAV_1755|M.avium_104 ASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMSPEG
Mb0458c|M.bovis_AF2122/97 AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
Rv0450c|M.tuberculosis_H37Rv AAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEG
MLBr_02378|M.leprae_Br4923 TAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAG
Mflv_3029|M.gilvum_PYR-GCK AAMNDDTFYLPPEAFETADFQRGIKLFLSPDGHAVRFTVFHQGDPLSEEG
TH_3260|M.thermoresistible__bu QARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEG
Mvan_1936|M.vanbaalenii_PYR-1 DSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATVEG
MSMEG_3584|M.smegmatis_MC2_155 AARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAMAQEG
MAB_4768c|M.abscessus_ATCC_199 ASRSDDFFYIPHEAFDNEDIKTGMTLMMSPDGKAARFIVTHMGNAMGPEG
: .** **:* *.*.. *.: .: ::*.**::.** : * *:. *
MMAR_3744|M.marinum_M ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MUL_3688|M.ulcerans_Agy99 ISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMIAVV
MAV_1755|M.avium_104 IKRVDAERTAAQEGLKQSSLSDARVYLGGTAATFKDMADGEKYDLMIAVV
Mb0458c|M.bovis_AF2122/97 IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
Rv0450c|M.tuberculosis_H37Rv IKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAI
MLBr_02378|M.leprae_Br4923 IASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGI
Mflv_3029|M.gilvum_PYR-GCK TSHIEPLRVAAVDAIKGTPLEGSTVYVGGSAATYKDMQQGADYDLLIAAV
TH_3260|M.thermoresistible__bu LAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAI
Mvan_1936|M.vanbaalenii_PYR-1 ISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIAGI
MSMEG_3584|M.smegmatis_MC2_155 IEHVEQIPDAIKMALKETSLAGAKVYLGGAASSTKDIQDYAASDLLIVAI
MAB_4768c|M.abscessus_ATCC_199 IEHVNDFPDAITTALKETSLAGAQVYIGGAGSNNKDIKQYAASDLLIAAI
: * .:* :.* .: :*:.*:.: :*: : **:*. :
MMAR_3744|M.marinum_M SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MUL_3688|M.ulcerans_Agy99 SALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIKI
MAV_1755|M.avium_104 SALTLIFMIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFGIRI
Mb0458c|M.bovis_AF2122/97 SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
Rv0450c|M.tuberculosis_H37Rv SSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHL
MLBr_02378|M.leprae_Br4923 SSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIEL
Mflv_3029|M.gilvum_PYR-GCK ASLILIFLIMVVLTRAIVAAAVIVGTVVLSLGASFGLSVLLWQHLIGIPL
TH_3260|M.thermoresistible__bu AAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEM
Mvan_1936|M.vanbaalenii_PYR-1 AAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGLAL
MSMEG_3584|M.smegmatis_MC2_155 AAFVLIFLIMLYLTRSLVAAMVIPGTVAFSFAGAFGLSVLVWQHLIGLPL
MAB_4768c|M.abscessus_ATCC_199 AAFTLIFLIMMVITRSLVAPFVIIGTVAFSFAGAFGLSVLIWQHLVGLPL
::. ***:**: :**:.:*. ** **. *:..:**:***:** :..: :
MMAR_3744|M.marinum_M HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MUL_3688|M.ulcerans_Agy99 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTGGVV
MAV_1755|M.avium_104 HWIVAALSVIILLAVGSDYNLLLVSRFREEIHGGLKTGIIRSMAGTGGVV
Mb0458c|M.bovis_AF2122/97 HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
Rv0450c|M.tuberculosis_H37Rv HWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVV
MLBr_02378|M.leprae_Br4923 HYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVV
Mflv_3029|M.gilvum_PYR-GCK HWMVLPMAVIVLLAVGADYNLLLVSRMKEEIYAGLNTGIIRSMAGSGSVV
TH_3260|M.thermoresistible__bu HWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVV
Mvan_1936|M.vanbaalenii_PYR-1 HWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGSVV
MSMEG_3584|M.smegmatis_MC2_155 HWLVLPLAFIILVAVGSDYNLLLISRVKEESGAGLNTALIRALGSTGAVV
MAB_4768c|M.abscessus_ATCC_199 HWLILPLTFIILVAVGSDYNLLLIARLKEETDAGLNTGLIRALGSTGGVV
*::: .::.*:*:***:*****:::*.::* .**:*.:**::..:* **
MMAR_3744|M.marinum_M TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MUL_3688|M.ulcerans_Agy99 TAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
MAV_1755|M.avium_104 TAAGLVFAFTMAAMLGSELRVLGQFGSTVCIGLLLDTLIVRTLLMPSIAT
Mb0458c|M.bovis_AF2122/97 TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
Rv0450c|M.tuberculosis_H37Rv TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
Mflv_3029|M.gilvum_PYR-GCK TAAGMVFAFTMMSMAVSNLTVIGQVGTTIGLGLLFDTFVVRSLMTPSLAA
TH_3260|M.thermoresistible__bu TAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIAT
Mvan_1936|M.vanbaalenii_PYR-1 TSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAVAA
MSMEG_3584|M.smegmatis_MC2_155 TSAGLVFAFTMLSMLASNLAAVGQLGSTVCIGLLLDTMIVRSLVVPCLLR
MAB_4768c|M.abscessus_ATCC_199 TSAGLVFAFTMLAMLASDLRTIGQVGTTVCIGLLLDTLIVRSFIVPALVR
* **:**..** : *:* .:.*.*:*: :***:**::**::: *.:
MMAR_3744|M.marinum_M LLGRWFWWPQVVHPRGDNARPRVAAPTH-------------
MUL_3688|M.ulcerans_Agy99 LLGRWFWWPQVVHPRGDNARPRVAAPTH-------------
MAV_1755|M.avium_104 LLGRWFWWPMVVHPRGDNARRPVPASS--------------
Mb0458c|M.bovis_AF2122/97 LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG
Rv0450c|M.tuberculosis_H37Rv LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD----
Mflv_3029|M.gilvum_PYR-GCK LFGKWFWWPMHVRQRPRARPWPTL--RSPQ-----------
TH_3260|M.thermoresistible__bu LLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV----
Mvan_1936|M.vanbaalenii_PYR-1 LLGRWFWWPQKVRSHASQRRLAALNH---------------
MSMEG_3584|M.smegmatis_MC2_155 LLGPWFWWPTFIRQRPLRTPDRFARPGPSRRIMTDR-----
MAB_4768c|M.abscessus_ATCC_199 LLGTWFWWPTRVLARPRREPVRS------------------
*:* ***** :