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VTDAATPENPFDLTGHVAVVTGGGSGIGLGMAEGLARAGAAVAILGRTASRLETAAEHLRRHARPVLPLV CDVADEQATTAAMARVRGEFGFLDSCFANAGVRGEFTPVLETSLEMFREVTRVDLDGVFVTLREAARQMI EAGRGGSLVAVSSLGAFQGMPRQPAYAASKAGVASLIDSMAVELARHGIRANTVAPGWFDTEMTADGLAD ERFRERVLPRVPARRWGAADDIGGVAVYLAGSASRYHTGDVLRIDGGYLKF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3379 | - | - | 100% (261) | 2-deoxy-D-gluconate 3-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 2e-41 | 37.90% (248) | 2-deoxy-D-gluconate 3-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3420 | - | 2e-39 | 38.96% (249) | gluconate 5-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 4e-41 | 38.40% (250) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0305 | - | 1e-117 | 81.01% (258) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 4e-41 | 38.40% (250) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-32 | 35.07% (268) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4913c | - | 4e-31 | 36.29% (248) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_2849 | - | 1e-39 | 37.20% (250) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 7e-39 | 37.05% (251) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3106 | - | 1e-51 | 44.00% (250) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0327 | - | 5e-36 | 39.43% (246) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0441 | - | 1e-122 | 82.38% (261) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M ----------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104 ------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAI
Mflv_0305|M.gilvum_PYR-GCK ------MTTTS--ANPFDLTGHVAVVTGGGSGIGLGMAGGLARAGATVAI
Mvan_0441|M.vanbaalenii_PYR-1 ------MTDAAPPANPFDLTGHVAVVTGGGSGIGLGMAEGLARAGATVAI
MSMEG_3379|M.smegmatis_MC2_155 ------MTDAATPENPFDLTGHVAVVTGGGSGIGLGMAEGLARAGAAVAI
TH_3106|M.thermoresistible__bu ---------------MTDLSGLTAIVTGGNSGIGRAMAVGIAKAGADVAI
MUL_0327|M.ulcerans_Agy99 ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MAB_4913c|M.abscessus_ATCC_199 -----------------MLQDKVVVVTGGSRGLGRAMVRAFAAHGADVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: . ::**.. *:* :. * :.:
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MMAR_2849|M.marinum_M AARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGELGGI
MAV_2775|M.avium_104 AARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELGGI
Mflv_0305|M.gilvum_PYR-GCK LGRNAQRLDDAAATLRTHG-NPVLPLVCDVTDEEAVTETMARIRDEFGWL
Mvan_0441|M.vanbaalenii_PYR-1 LGRSAQRLDSAAATLRSHG-NPVLPVVCDVTDEQAVTDAMARIRSEFGWL
MSMEG_3379|M.smegmatis_MC2_155 LGRTASRLETAAEHLRRHA-RPVLPLVCDVADEQATTAAMARVRGEFGFL
TH_3106|M.thermoresistible__bu WARNAERNAEVVEEIAALG-RRAIAIACDVTDETAVIDAMEQTVADLGPL
MUL_0327|M.ulcerans_Agy99 WERDPQTCAQAAAELGGLG------IATDVRSGDQVDAALQRTQAELGAV
MAB_4913c|M.abscessus_ATCC_199 ASRKIDSCQELAAQVEAEHGRRALPVACNVSSWEQCDHLVDTVYREFGRV
MLBr_01807|M.leprae_Br4923 THR------ASVVPDWFFG------VECDVTDNDAIGAAFKAVEEHQGPV
* . : :* . . . * :
Mb1963c|M.bovis_AF2122/97 DIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQG
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQG
MMAR_2849|M.marinum_M DIAVCNAGIV-SVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQG
MAV_2775|M.avium_104 DIAVCNAGII-SVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQG
Mflv_0305|M.gilvum_PYR-GCK DSCFANAGVRGRFTPVLETSLAEFRSVTSVDLDGVFLTLREAARQMVAAG
Mvan_0441|M.vanbaalenii_PYR-1 DSCFANAGVRGTFTPTLDTSLAEFREVTRVDLDGVFVTLREAARQMIGAG
MSMEG_3379|M.smegmatis_MC2_155 DSCFANAGVRGEFTPVLETSLEMFREVTRVDLDGVFVTLREAARQMIEAG
TH_3106|M.thermoresistible__bu GCFVANAGTS-EYVPIAEMSLDTWHRILRTNLDGTFLCTREAARRFIAQG
MUL_0327|M.ulcerans_Agy99 TILVNNVGGV-FWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAG
MAB_4913c|M.abscessus_ATCC_199 DVLVNNAGLSPLYPSLDQVSEALFDKVIGVNLKGPFRLSASIATKMAAG-
MLBr_01807|M.leprae_Br4923 EVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
. *.* . : : :: : : :
Mb1963c|M.bovis_AF2122/97 QGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
Rv1928c|M.tuberculosis_H37Rv QGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
MMAR_2849|M.marinum_M LGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRV
MAV_2775|M.avium_104 RGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRV
Mflv_0305|M.gilvum_PYR-GCK RGGSLVGVSSLGAFQG--MPRQPAYAASKAGVTSMMDSFAVELARHGIRA
Mvan_0441|M.vanbaalenii_PYR-1 RGGSLVGVSSLGAVQG--MPRQPAYAASKAGVTSLMDSLAVEFARYGIRA
MSMEG_3379|M.smegmatis_MC2_155 RGGSLVAVSSLGAFQG--MPRQPAYAASKAGVASLIDSMAVELARHGIRA
TH_3106|M.thermoresistible__bu SGGSIVVLSSTISRYG--GAGLGAYATSKTGLLGLSRTLAVELARHKVRC
MUL_0327|M.ulcerans_Agy99 LPGSIMAITSIEGVRA--APGYAAYAAAKAGVVNYTKTTALELAHHGIRV
MAB_4913c|M.abscessus_ATCC_199 AGGSIINISSIEAVRP--DATALPYAAAKAGLNALTLGLSHTFG-PTVRT
MLBr_01807|M.leprae_Br4923 FGRYIFMG-SVVGLSG--VPGQANYAASKSGLIGMARSLARELGSRSITA
:. * . *.::*:.: : :. :
Mb1963c|M.bovis_AF2122/97 NSVSPGYILTELVEP---YTEYQPLWEPKIPLGRLGRPEELA--GLYLYL
Rv1928c|M.tuberculosis_H37Rv NSVSPGYILTELVEP---YTEYQPLWEPKIPLGRLGRPEELA--GLYLYL
MMAR_2849|M.marinum_M NSVSPGYIRTELVEP---LADYHALWEPKIPLGRMGRPEELT--GLYLYL
MAV_2775|M.avium_104 NSVSPGYIRTELVEP---LHEYHRQWQPKIPLGRMGRPDELA--GIYLYL
Mflv_0305|M.gilvum_PYR-GCK NTVAPGWFETEMTSEGMADERFTSRVLPRVPVRRWGAAEDVAGVGVAVYL
Mvan_0441|M.vanbaalenii_PYR-1 NTIQPGWFATEMTADGMADERFRARVLPRVPVRRWGAAEDVG--GIAVYL
MSMEG_3379|M.smegmatis_MC2_155 NTVAPGWFDTEMTADGLADERFRERVLPRVPARRWGAADDIG--GVAVYL
TH_3106|M.thermoresistible__bu NTLIPGWTRTALTAALQADERFMAATTGRTPVRRWADPHEFE--EVAAFL
MUL_0327|M.ulcerans_Agy99 NAIAPDITMTEGLAQ-LGGAAALERIGSLVPLGRPGDVDEIA--SVAVFL
MAB_4913c|M.abscessus_ATCC_199 NTIQCGLFNTDIAAAWP--EGFAEALIPSIPLRRVGEPEDIV--GAALYL
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMTRA--MDSKYQEAALQAIPLGRIGAVEEIA--GAVSFL
* : . * * * . .:. :*
Mb1963c|M.bovis_AF2122/97 ASEASSYMTGSDIVIDGGYTCP-----------------
Rv1928c|M.tuberculosis_H37Rv ASEASSYMTGSDIVIDGGYTCP-----------------
MMAR_2849|M.marinum_M ASAASSYMTGSDIVIDGGYTCP-----------------
MAV_2775|M.avium_104 ASAASSYMTGSDIVIDGGYSCP-----------------
Mflv_0305|M.gilvum_PYR-GCK AGPASAYHTGDVLRLDGGYLKF-----------------
Mvan_0441|M.vanbaalenii_PYR-1 ASPASAYHTGDVLRLDGGYLKF-----------------
MSMEG_3379|M.smegmatis_MC2_155 AGSASRYHTGDVLRIDGGYLKF-----------------
TH_3106|M.thermoresistible__bu ADPTLTFHTGNEVIVDGGYTIF-----------------
MUL_0327|M.ulcerans_Agy99 ASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG
MAB_4913c|M.abscessus_ATCC_199 ASEASAYCTGTTIRLDGGIL-------------------
MLBr_01807|M.leprae_Br4923 ASEDAGYISGAVIPVDGGLGMGH----------------
*. : :* : :***