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M. thermoresistible (build 8) TH_3106 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 2302374 - 2303129
length: 252

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3106--100% (252)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3505-6e-3637.40% (246) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_2879-1e-3336.22% (254) PUTATIVE putative short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1963c-6e-3832.13% (249) short chain dehydrogenase
M. gilvum PYR-GCKMflv_0305-2e-5143.65% (252) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1928c-6e-3832.13% (249) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG12e-2632.35% (238) 3-oxoacyl-
M. abscessus ATCC 19977MAB_3844c-1e-2933.21% (268) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_2849-1e-4036.55% (249) short-chain type dehydrogenase/reductase
M. avium 104MAV_2775-2e-3634.80% (250) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_3379-2e-5144.00% (250) 2-deoxy-D-gluconate 3-dehydrogenase
M. ulcerans Agy99MUL_0327-2e-3636.48% (244) oxidoreductase
M. vanbaalenii PYR-1Mvan_0441-1e-5244.40% (250) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1963c|M.bovis_AF2122/97           ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv        ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M               ----------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104                ------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAI
Mflv_0305|M.gilvum_PYR-GCK          ------MTTTS--ANPFDLTGHVAVVTGGGSGIGLGMAGGLARAGATVAI
Mvan_0441|M.vanbaalenii_PYR-1       ------MTDAAPPANPFDLTGHVAVVTGGGSGIGLGMAEGLARAGATVAI
MSMEG_3379|M.smegmatis_MC2_155      ------MTDAATPENPFDLTGHVAVVTGGGSGIGLGMAEGLARAGAAVAI
TH_3106|M.thermoresistible__bu      ---------------MTDLSGLTAIVTGGNSGIGRAMAVGIAKAGADVAI
MUL_0327|M.ulcerans_Agy99           ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
MAB_3844c|M.abscessus_ATCC_199      -------------MADQPLAGKVAFVTGAARGQGRQHAVRLAQAGADVVA
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .   .:**.  * *   *      *  :. 

Mb1963c|M.bovis_AF2122/97           AARHL-------------DALEKLADEIGTSG-GKVVPVCCDVSQHQQVT
Rv1928c|M.tuberculosis_H37Rv        AARHL-------------DALEKLADEIGTSG-GKVVPVCCDVSQHQQVT
MMAR_2849|M.marinum_M               AARHS-------------DALQVVADEIAGVG-GKALPIRCDVTQPDQVR
MAV_2775|M.avium_104                AARDF-------------EALQRTADELTAGGTGGVVAIRCDVTQPDEVS
Mflv_0305|M.gilvum_PYR-GCK          LGRNA-------------QRLDDAAATLRTHGNPVLP-LVCDVTDEEAVT
Mvan_0441|M.vanbaalenii_PYR-1       LGRSA-------------QRLDSAAATLRSHGNPVLP-VVCDVTDEQAVT
MSMEG_3379|M.smegmatis_MC2_155      LGRTA-------------SRLETAAEHLRRHARPVLP-LVCDVADEQATT
TH_3106|M.thermoresistible__bu      WARNA-------------ERNAEVVEEIAALGRRAIA-IACDVTDETAVI
MUL_0327|M.ulcerans_Agy99           WERDP-------------QTCAQAAAELGGLG------IATDVRSGDQVD
MAB_3844c|M.abscessus_ATCC_199      IDACAPVSEYAGYEAATPEDLKETVRLVEAAG-RKIIAEQADVRNGAALQ
MLBr_01807|M.leprae_Br4923          THRAS-------------------VVPDWFFG------VECDVTDNDAIG
                                                            .      .         ** .     

Mb1963c|M.bovis_AF2122/97           SMLDQVTAELGGIDIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFL
Rv1928c|M.tuberculosis_H37Rv        SMLDQVTAELGGIDIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFL
MMAR_2849|M.marinum_M               GMLDQMTGELGGIDIAVCNAGIV-SVQAMLDMPLEEFQRIQDTNVTGVFL
MAV_2775|M.avium_104                GMVDRMIAELGGIDIAVCNAGII-SVSPMLEMPAAEFQRIQDTNVTGVFL
Mflv_0305|M.gilvum_PYR-GCK          ETMARIRDEFGWLDSCFANAGVRGRFTPVLETSLAEFRSVTSVDLDGVFL
Mvan_0441|M.vanbaalenii_PYR-1       DAMARIRSEFGWLDSCFANAGVRGTFTPTLDTSLAEFREVTRVDLDGVFV
MSMEG_3379|M.smegmatis_MC2_155      AAMARVRGEFGFLDSCFANAGVRGEFTPVLETSLEMFREVTRVDLDGVFV
TH_3106|M.thermoresistible__bu      DAMEQTVADLGPLGCFVANAGTS-EYVPIAEMSLDTWHRILRTNLDGTFL
MUL_0327|M.ulcerans_Agy99           AALQRTQAELGAVTILVNNVGGV-FWSPLLQTSEKGWDALYRSNLGHVLL
MAB_3844c|M.abscessus_ATCC_199      SVVEEAVAQFGHIDILIANAGVL-SWGRLWEMSDQQWEDIIDTNLTGTWK
MLBr_01807|M.leprae_Br4923          AAFKAVEEHQGPVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFR
                                      .     . * :   . *.*           .   :  :   ::  .  

Mb1963c|M.bovis_AF2122/97           TAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTK
Rv1928c|M.tuberculosis_H37Rv        TAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTK
MMAR_2849|M.marinum_M               TAQAAARAMVDQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTK
MAV_2775|M.avium_104                TAQAAARAMVRQGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTK
Mflv_0305|M.gilvum_PYR-GCK          TLREAARQMVAAGRGGSLVGVSSLGAFQG--MPRQPAYAASKAGVTSMMD
Mvan_0441|M.vanbaalenii_PYR-1       TLREAARQMIGAGRGGSLVGVSSLGAVQG--MPRQPAYAASKAGVTSLMD
MSMEG_3379|M.smegmatis_MC2_155      TLREAARQMIEAGRGGSLVAVSSLGAFQG--MPRQPAYAASKAGVASLID
TH_3106|M.thermoresistible__bu      CTREAARRFIAQGSGGSIVVLSSTISRYG--GAGLGAYATSKTGLLGLSR
MUL_0327|M.ulcerans_Agy99           CTQRVARRLVAAGLPGSIMAITSIEGVRA--APGYAAYAAAKAGVVNYTK
MAB_3844c|M.abscessus_ATCC_199      TVKAVVPTMIEAGNGGSIVIVSSVSGLKG--TPGNGAYVASKFGLTGLTK
MLBr_01807|M.leprae_Br4923          VAKLASRNMIKQRFG-RYIFMGSVVGLSG--VPGQANYAASKSGLIGMAR
                                      : .   ::        :   *  .           * ::* .:     

Mb1963c|M.bovis_AF2122/97           AMAVELAPHKIRVNSVSPGYILTELVEP---YTEYQPLWEPKIPLG----
Rv1928c|M.tuberculosis_H37Rv        AMAVELAPHKIRVNSVSPGYILTELVEP---YTEYQPLWEPKIPLG----
MMAR_2849|M.marinum_M               AMAVELAPHQIRVNSVSPGYIRTELVEP---LADYHALWEPKIPLG----
MAV_2775|M.avium_104                AMAVEFAPHDIRVNSVSPGYIRTELVEP---LHEYHRQWQPKIPLG----
Mflv_0305|M.gilvum_PYR-GCK          SFAVELARHGIRANTVAPGWFETEMTSEGMADERFTSRVLPRVPVR----
Mvan_0441|M.vanbaalenii_PYR-1       SLAVEFARYGIRANTIQPGWFATEMTADGMADERFRARVLPRVPVR----
MSMEG_3379|M.smegmatis_MC2_155      SMAVELARHGIRANTVAPGWFDTEMTADGLADERFRERVLPRVPAR----
TH_3106|M.thermoresistible__bu      TLAVELARHKVRCNTLIPGWTRTALTAALQADERFMAATTGRTPVR----
MUL_0327|M.ulcerans_Agy99           TTALELAHHGIRVNAIAPDITMTEGLAQ-LGGAAALERIGSLVPLG----
MAB_3844c|M.abscessus_ATCC_199      SLTIELAEYGIRVNSIHPYGVTTPMITGDAMMKILAEHPNYLPSIAPMPL
MLBr_01807|M.leprae_Br4923          SLARELGSRSITANVVAPGFIDTEMTRA--MDSKYQEAALQAIPLG----
                                    : : *:.   :  * : *    *                    .      

Mb1963c|M.bovis_AF2122/97           ---RLGRPEELA--GLYLYLASEASSYMTGSDIVIDGGYTCP--------
Rv1928c|M.tuberculosis_H37Rv        ---RLGRPEELA--GLYLYLASEASSYMTGSDIVIDGGYTCP--------
MMAR_2849|M.marinum_M               ---RMGRPEELT--GLYLYLASAASSYMTGSDIVIDGGYTCP--------
MAV_2775|M.avium_104                ---RMGRPDELA--GIYLYLASAASSYMTGSDIVIDGGYSCP--------
Mflv_0305|M.gilvum_PYR-GCK          ---RWGAAEDVAGVGVAVYLAGPASAYHTGDVLRLDGGYLKF--------
Mvan_0441|M.vanbaalenii_PYR-1       ---RWGAAEDVG--GIAVYLASPASAYHTGDVLRLDGGYLKF--------
MSMEG_3379|M.smegmatis_MC2_155      ---RWGAADDIG--GVAVYLAGSASRYHTGDVLRIDGGYLKF--------
TH_3106|M.thermoresistible__bu      ---RWADPHEFE--EVAAFLADPTLTFHTGNEVIVDGGYTIF--------
MUL_0327|M.ulcerans_Agy99           ---RPGDVDEIA--SVAVFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQ
MAB_3844c|M.abscessus_ATCC_199      SPTKMLEPDEIS--DVVLWLASDASGTLAGAQVPVDKGHLTY--------
MLBr_01807|M.leprae_Br4923          ---RIGAVEEIA--GAVSFLASEDAGYISGAVIPVDGGLGMGH-------
                                       :    .:.       :**.      :*  : :* *            

Mb1963c|M.bovis_AF2122/97           ---------
Rv1928c|M.tuberculosis_H37Rv        ---------
MMAR_2849|M.marinum_M               ---------
MAV_2775|M.avium_104                ---------
Mflv_0305|M.gilvum_PYR-GCK          ---------
Mvan_0441|M.vanbaalenii_PYR-1       ---------
MSMEG_3379|M.smegmatis_MC2_155      ---------
TH_3106|M.thermoresistible__bu      ---------
MUL_0327|M.ulcerans_Agy99           TGEYRLGPG
MAB_3844c|M.abscessus_ATCC_199      ---------
MLBr_01807|M.leprae_Br4923          ---------