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MTEWFLFLPQVRLEIGDIVERARIAEAAGFDGIAFIDHLEAPGATHQGIWEAMTTATWVAAHTERLRIGH LVLCDAFRHPAVLAKQAVTLSTASDGRFELGLGSGSWPQEFFRFGVDGGDDAAARVDRLERDLALLREHW GEGERGQVPAPAHKIPLVIGGTGRRTMGLVRRYADWWNIPSHQLDRLPDLLPTVGAARASMQQMVGFVGR GIDRAAVTERSSRLFGHLGSGLVCGDAAELTEHFAGLAAQGIERFYVWFADFAAPQTISEFAETVMHTGQ KGTT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2996 | - | - | 100% (284) | hypothetical protein MSMEG_2996 |
| M. smegmatis MC2 155 | MSMEG_1749 | - | 2e-18 | 32.11% (190) | putative monooxygenase |
| M. smegmatis MC2 155 | MSMEG_0702 | - | 4e-17 | 26.42% (299) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2917 | - | 2e-18 | 37.50% (168) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4098 | - | 7e-32 | 40.10% (197) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2893 | - | 2e-18 | 37.50% (168) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 3e-07 | 30.97% (155) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2431c | - | 1e-16 | 33.51% (191) | luciferase-like oxidoreductase |
| M. marinum M | MMAR_3978 | - | 1e-104 | 65.58% (276) | coenzyme F420-dependent oxidoreductase |
| M. avium 104 | MAV_1632 | - | 1e-105 | 67.63% (278) | hypothetical protein MAV_1632 |
| M. thermoresistible (build 8) | TH_0538 | - | 1e-124 | 75.27% (279) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3839 | - | 1e-103 | 64.49% (276) | coenzyme F420-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2247 | - | 9e-34 | 30.90% (301) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2996|M.smegmatis_MC2_155 --MTEWFLFLPQVRLE--IGDIVERA--------RIAEAAGFDGIAFIDH
TH_0538|M.thermoresistible__bu --VAEWFLFLPQVRFR--LAEIVERA--------RVAETSGFDGIAFIDH
MMAR_3978|M.marinum_M --MIEWFLFLPQLRLA--VPEFVQRA--------MCAEDAGFDGVAFIDH
MUL_3839|M.ulcerans_Agy99 --MIEWFLFLPQLRLA--VSEFVQRA--------MCAEDAGFDGVAFIDH
MAV_1632|M.avium_104 --MVEWYLFLPQVRLS--AADIAERA--------RRAEASGFDGIVFIDH
Mflv_4098|M.gilvum_PYR-GCK MRRPEIGVYLPQMGFS--FDEVLHRA--------RRCEDLGIDSLWLYDH
Mvan_2247|M.vanbaalenii_PYR-1 MSRPEIGVYLPQMGFS--FDELLHRA--------RRCEKLGIDSLWLYDH
Mb2917|M.bovis_AF2122/97 MTVASTAHHTRRLRFG--LAAPLPRAGTQMRAFAQAVEAAGFDVLAFPDH
Rv2893|M.tuberculosis_H37Rv MTVASTAHHTRRLRFG--LAAPLPRAGTQMRAFAQAVEAAGFDVLAFPDH
MAB_2431c|M.abscessus_ATCC_199 -MTIRLGYQIPNFSYGTGVAELFPTVVK----QVREAEASGFDTVFVMDH
MLBr_00348|M.leprae_Br4923 -MVERANAMKLGLQLGYWAAQPPGNA---------AELVAAAEGAGFDAV
. . . : .
MSMEG_2996|M.smegmatis_MC2_155 LEAPGAT---HQGIWEAMTTATWVAAHTERLRIGHLVLCDAFRHPAVLAK
TH_0538|M.thermoresistible__bu LEAPGAT---HQGIWEAMTVATWVAAHTERLRIGHLVLCDAFRHPAVLAK
MMAR_3978|M.marinum_M LEAPGQR---DESIWEAMSIATWVAAKTSRLRVGHLVLCDAFRHPAVLAK
MUL_3839|M.ulcerans_Agy99 LEAPGQR---DESIWEAMSIATWVAAKTSRLRVGHLVLCDAFRHPAVLAK
MAV_1632|M.avium_104 LEAPGLR---DENIWEAMGIATWVAAKTERLRIGHLVLCDAFRHPAVLAK
Mflv_4098|M.gilvum_PYR-GCK LYGPGMP---DYPSMEAWTLATALLSRTERLRIGHMVLCNQFRHPVTLAK
Mvan_2247|M.vanbaalenii_PYR-1 LYGPGMP---DYPSMEAWTLATALLSRTDTLRVGHMVLCNQFRHPVTLAK
Mb2917|M.bovis_AF2122/97 LVPS----------VSPFAGATAAAMATQRLHTGTLVLNNDFRHPVDTAR
Rv2893|M.tuberculosis_H37Rv LVPS----------VSPFAGATAAAMATQRLHTGTLVLNNDFRHPVDTAR
MAB_2431c|M.abscessus_ATCC_199 FYQLPMIGTPDQPMLEAYTALGALASATSTIQLSTLVTGNTYRNPALLAK
MLBr_00348|M.leprae_Br4923 FTGEAWG-------SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAM
: .. *. :: . * * *. *
MSMEG_2996|M.smegmatis_MC2_155 QAVTLSTASDGRFELGLGSGSWPQEFFRFGVDGGDDAAARVDRLERDLAL
TH_0538|M.thermoresistible__bu QAVTLAAATGGRFELGLGWGSWPQEFDRFGIDDGHDAPARVRRLARTLEL
MMAR_3978|M.marinum_M QAVTLSAASGGRFELGLGAGSWPVEFTRFEVGQ-QNPVDRVRQLERDLRL
MUL_3839|M.ulcerans_Agy99 EAVTLSAASGGRFELGLGAGSWPVDFTRFEVGQ-QNPVDRVRQLERDLRL
MAV_1632|M.avium_104 QAVTLSEASEGRFELGLGAGSWPAEFARFDVGQ-QDPKARVAQLARHLEL
Mflv_4098|M.gilvum_PYR-GCK MVTTLDQISGGRLSLGIGSGSIEDEHRRAGLPW-GTFAERSAQLGETLQI
Mvan_2247|M.vanbaalenii_PYR-1 MATTLDQISGGRLSLGIGSGSIEDEHRRAGLPW-GSFAERSEQLGETLQI
Mb2917|M.bovis_AF2122/97 EAAGVATLAEGRFELGLGAGHRRSEYDAAGITF-DSGATRVARLIESAHL
Rv2893|M.tuberculosis_H37Rv EAAGVATLAEGRFELGLGAGHRRSEYDAAGITF-DSGATRVARLIESAHL
MAB_2431c|M.abscessus_ATCC_199 AVTTLDVVSGGRAILGIGAGWFELEHQQLGFEF-GTFTDRFERLTEALEI
MLBr_00348|M.leprae_Br4923 AALTLDHLSGGRHILGLGVSGPQVVEGWYGQPF----PKPLSRTREYIDI
. : : ** **:* . : . :
MSMEG_2996|M.smegmatis_MC2_155 LREHWGEGERG--------------QVPAP-----------AHKIPLVIG
TH_0538|M.thermoresistible__bu LPRYWGADDHDDL-----------VQQPVP-----------EHPIPLVLG
MMAR_3978|M.marinum_M IMRYWGDT--DE------------AQRPRP-----------LYPIPLLLG
MUL_3839|M.ulcerans_Agy99 IMRYWGDT--DE------------AQRPRP-----------WYPIPLLLG
MAV_1632|M.avium_104 IKRYWGDDGRGE------------AQAPRR-----------SHPIPLVLG
Mflv_4098|M.gilvum_PYR-GCK LRQAFTDERVDFAGRHFTVTDFPIKPGPVQ-----------KSGPPIVVG
Mvan_2247|M.vanbaalenii_PYR-1 LHQAFGDERIDFTGKHFTVTDMPIKPGPVQ-----------RPRPPIVVG
Mb2917|M.bovis_AF2122/97 IRALLDAEPVDFDGQHYRVHAEAGSLVAPP-----------KVRVPLLVG
Rv2893|M.tuberculosis_H37Rv IRALLDAEPVDFDGQHYRVHAEAGSLVAPP-----------KVRVPLLVG
MAB_2431c|M.abscessus_ATCC_199 IPPMLRGERPTFEGKYYR--TESALNEPRL-----------RPNIPIMIG
MLBr_00348|M.leprae_Br4923 VRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLG
: . *:::*
MSMEG_2996|M.smegmatis_MC2_155 GTGRR-TMGLVRRYADWWNIP--------------SHQLDRLPDLLPTVG
TH_0538|M.thermoresistible__bu GTGKR-TMELVRQYAHWWNVP--------------SHQLDRLPELLPTIG
MMAR_3978|M.marinum_M GSGPR-MMRLVAQYADWWNLQ--------------ANQLDRLPRLASSVG
MUL_3839|M.ulcerans_Agy99 GSGPR-MMRLVAQYADWWNLQ--------------ANQLDRLPRLASSVG
MAV_1632|M.avium_104 GSGPR-MMELVRTHADWWNLP--------------ANKLDKLPALAPAAG
Mflv_4098|M.gilvum_PYR-GCK GVGEKYTLPLVARYADVWNVP--------------TYALDQIEPKIAVLR
Mvan_2247|M.vanbaalenii_PYR-1 GVGEKFTLPLVARYADVWNVP--------------TYALGQIKEKIAALR
Mb2917|M.bovis_AF2122/97 GNGTE-VLRLGGRIADIVGLAGISHNRDATQVRFTHFDADGLADRIAVVR
Rv2893|M.tuberculosis_H37Rv GNGTE-VLRLGGRIADIVGLAGISHNRDATQVRFTHFDADGLADRIAVVR
MAB_2431c|M.abscessus_ATCC_199 GSGEKKTFGLAVKYADHLNLLS---------------SLDEIPHKLTVLR
MLBr_00348|M.leprae_Br4923 AEGPK-NVALAAEICDGWLPIFFS-----------PRMADMYNEWLDEGF
. * . . * .. .
MSMEG_2996|M.smegmatis_MC2_155 -----------AARASMQQMVGFVGRGIDRAAVTERSSRLFGHLGSGL--
TH_0538|M.thermoresistible__bu -----------SARASVQQMVGFVGEDADRDAVTEVSRRRFGHLGDGL--
MMAR_3978|M.marinum_M -----------SARISVQQMVGFVRSGEDPASVREVSTRRFAHLGTGL--
MUL_3839|M.ulcerans_Agy99 -----------SARISVQQMVGFVRSGEDSASVREVSTRRFAHLGTGL--
MAV_1632|M.avium_104 -----------SARLSIQQMVGFVRAGQDPEKVREVSTRRFGNLGSGL--
Mflv_4098|M.gilvum_PYR-GCK SICEDIGRDPDSIVLSIEAVMAVAPDQESLESVRMLAEKRFRGPGFGLHD
Mvan_2247|M.vanbaalenii_PYR-1 SICEDVGRDPQTITLSIEAVMALAPDEASLPTVRSLAEKRFGGEGFGLHD
Mb2917|M.bovis_AF2122/97 HAAG-----DRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQVL
Rv2893|M.tuberculosis_H37Rv HAAG-----DRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQVL
MAB_2431c|M.abscessus_ATCC_199 QRCEEAG--RDPSTLETSAFFSVFIDD-DSATAWKLAASQLSQNGIDLDT
MLBr_00348|M.leprae_Br4923 ARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTN
.. :
MSMEG_2996|M.smegmatis_MC2_155 -------------VCGDAAELTEHFAG-LAAQGIERFYVWFADFAAPQTI
TH_0538|M.thermoresistible__bu -------------RCGDAAELADHFGA-LAAQGVERFYVWFADFAQPQTL
MMAR_3978|M.marinum_M -------------VCGGAGEMIEHFAG-LAAQGVQRFYVWFADFAAADTL
MUL_3839|M.ulcerans_Agy99 -------------VCGGAGEMIEHFAG-LAAQGVQRFYVWFADFAAADTL
MAV_1632|M.avium_104 -------------VCGDADELIGHFSG-LAAQRVERFYVWFADFAAPDSL
Mflv_4098|M.gilvum_PYR-GCK TG-----------LIGTPAEIAAKLGR-LVEIGFGQIVLFTHDRCSDQTL
Mvan_2247|M.vanbaalenii_PYR-1 TD-----------LIGTPAEMVDRLGA-LAEMGFGQIVLFTHDRCSDQTL
Mb2917|M.bovis_AF2122/97 ESPFL--------LLGTHEQMAEALAA-RQRRFGVSYWTVFDEWAGRASA
Rv2893|M.tuberculosis_H37Rv ESPFL--------LLGTHEQMAEALAA-RQRRFGVSYWTVFDEWAGRASA
MAB_2431c|M.abscessus_ATCC_199 LPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLNAPATGHLPGV
MLBr_00348|M.leprae_Br4923 FHADVYR------RMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMI
* :
MSMEG_2996|M.smegmatis_MC2_155 SEFAETVMHTGQKGTT-----------------------
TH_0538|M.thermoresistible__bu AEFADTVIRAR----------------------------
MMAR_3978|M.marinum_M AEFGESVIKEFADPR------------------------
MUL_3839|M.ulcerans_Agy99 AEFGESAIKEFADPR------------------------
MAV_1632|M.avium_104 REFGESVITAFPAR-------------------------
Mflv_4098|M.gilvum_PYR-GCK ELLASEIIPRL----------------------------
Mvan_2247|M.vanbaalenii_PYR-1 ELLAAEVIPRL----------------------------
Mb2917|M.bovis_AF2122/97 MRDIAEVIALLRYG-------------------------
Rv2893|M.tuberculosis_H37Rv MRDIAEVIALLRYG-------------------------
MAB_2431c|M.abscessus_ATCC_199 VELIGNTLRPLFKN-------------------------
MLBr_00348|M.leprae_Br4923 VGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF