For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRRPEIGVYLPQMGFSFDEVLHRARRCEDLGIDSLWLYDHLYGPGMPDYPSMEAWTLATALLSRTERLRI GHMVLCNQFRHPVTLAKMVTTLDQISGGRLSLGIGSGSIEDEHRRAGLPWGTFAERSAQLGETLQILRQA FTDERVDFAGRHFTVTDFPIKPGPVQKSGPPIVVGGVGEKYTLPLVARYADVWNVPTYALDQIEPKIAVL RSICEDIGRDPDSIVLSIEAVMAVAPDQESLESVRMLAEKRFRGPGFGLHDTGLIGTPAEIAAKLGRLVE IGFGQIVLFTHDRCSDQTLELLASEIIPRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4098 | - | - | 100% (310) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_0268 | - | 1e-44 | 34.41% (311) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_3347 | - | 2e-39 | 35.74% (277) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 6e-40 | 30.67% (326) | hypothetical protein Mb0815c |
| M. tuberculosis H37Rv | Rv0791c | - | 7e-40 | 30.67% (326) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00269 | - | 6e-14 | 25.23% (325) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4797 | - | 4e-39 | 38.64% (220) | luciferase-like monooxygenase |
| M. marinum M | MMAR_2729 | - | 6e-40 | 35.15% (293) | oxidoreductase |
| M. avium 104 | MAV_0986 | - | 1e-39 | 32.63% (334) | hypothetical protein MAV_0986 |
| M. smegmatis MC2 155 | MSMEG_0702 | - | 2e-40 | 32.79% (308) | monooxygenase |
| M. thermoresistible (build 8) | TH_2824 | - | 3e-45 | 33.76% (311) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3024 | - | 1e-39 | 35.15% (293) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2247 | - | 1e-157 | 85.48% (310) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4098|M.gilvum_PYR-GCK -------------------MRRPE---IGVYLPQMGFSFDEVLHRARRCE
Mvan_2247|M.vanbaalenii_PYR-1 -------------------MSRPE---IGVYLPQMGFSFDELLHRARRCE
Mb0815c|M.bovis_AF2122/97 -----------MNAKDDPHFGLML---AATVNGLAVGSYREMVVVSQTAE
Rv0791c|M.tuberculosis_H37Rv -----------MNAKDDPHFGLML---AATVNGLAVGSYREMVVVSQTAE
MSMEG_0702|M.smegmatis_MC2_155 ---------------------MDF---RVFVEPQQGATYSDQLAVAQAAE
TH_2824|M.thermoresistible__bu ---------------------MDF---RVFVEPQQGGTYADQLAVARAAE
MMAR_2729|M.marinum_M -------------MAIRLGFQIPS----FSYGTGVDKLFPSVIAQAREAE
MUL_3024|M.ulcerans_Agy99 -------------MAIRLGFQIPS----FSYGTGVDKLFPSVIAQAREAE
MAB_4797|M.abscessus_ATCC_1997 -----------------MRFDIKT----ANHNTTWQEILS---VWKEADD
MAV_0986|M.avium_104 MKTVAVRPVRLESRGMRFGLFIPQGWRMDLVGIEPDEHWAVMRDLAQRAD
MLBr_00269|M.leprae_Br4923 -------------------MAELR---LGYKASAEQFAPRELVELGVAAE
:
Mflv_4098|M.gilvum_PYR-GCK DLG-IDSLWLYDHLYGPG-------------------------MPDYPS-
Mvan_2247|M.vanbaalenii_PYR-1 KLG-IDSLWLYDHLYGPG-------------------------MPDYPS-
Mb0815c|M.bovis_AF2122/97 EYG-FDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
Rv0791c|M.tuberculosis_H37Rv EYG-FDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
MSMEG_0702|M.smegmatis_MC2_155 RLG-YSAFFRSDHYLKMA-----------------------GDGLPGPT-
TH_2824|M.thermoresistible__bu DLG-YSAFFRSDHYLAMS-----------------------GDGLPGPT-
MMAR_2729|M.marinum_M AAG-FDSLFLMDHFYQLPM-----------------------LGTPDQ--
MUL_3024|M.ulcerans_Agy99 AAG-FDSLFLMDHFYQLPM-----------------------LGTPDQ--
MAB_4797|M.abscessus_ATCC_1997 IEV-FHTGWLFDHFYPIAS-----------------------PSQRDHNS
MAV_0986|M.avium_104 RDVGWDSLWVYDHFHTVPV-----------------------PTGEAT--
MLBr_00269|M.leprae_Br4923 AHG-MDSATVSDHFQPWRH------------------------QGGHAS-
: **
Mflv_4098|M.gilvum_PYR-GCK ----MEAWTLATALLSRTERLRIGHMVLCNQFRH-PVTLAKMVTTLDQIS
Mvan_2247|M.vanbaalenii_PYR-1 ----MEAWTLATALLSRTDTLRVGHMVLCNQFRH-PVTLAKMATTLDQIS
Mb0815c|M.bovis_AF2122/97 SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVIS
Rv0791c|M.tuberculosis_H37Rv SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVIS
MSMEG_0702|M.smegmatis_MC2_155 -----DSWVTLAGIARETSTIRLGTMVTSATFRY-PGPLAISVAQVDEMS
TH_2824|M.thermoresistible__bu -----DSWVTLAGIARETTSIRLGTLVTSATFRY-PGPLAISVAQVDEMS
MMAR_2729|M.marinum_M --PMLEAYTALGALATATERLQLGTLVTGNTYRN-PALLAKIITTLDVVS
MUL_3024|M.ulcerans_Agy99 --PMLEAYTALGALATATERLQLGTLVTGNTYRN-PALLAKIITTLDVVS
MAB_4797|M.abscessus_ATCC_1997 AGPCLEGWMLLSALAQETSRLRLGTLVTGIHYRH-PAILANMAATADIVS
MAV_0986|M.avium_104 ----HEAWSLMAAYAAVTSRIKLGQMCTAMSYRN-PVYLAKVAATADIIS
MLBr_00269|M.leprae_Br4923 -----FSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLY
. * : :* :* * :. : . :
Mflv_4098|M.gilvum_PYR-GCK GGRLSLGIGSGSIEDEHR-RAGLPWGTFAERSAQLGETLQILRQAFT---
Mvan_2247|M.vanbaalenii_PYR-1 GGRLSLGIGSGSIEDEHR-RAGLPWGSFAERSEQLGETLQILHQAFG---
Mb0815c|M.bovis_AF2122/97 QGRLDLGLGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPN
Rv0791c|M.tuberculosis_H37Rv QGRLDLGLGAGWFRRESQ-AYGIPFPPVGDRVSALAESLQVIKAVWTEPN
MSMEG_0702|M.smegmatis_MC2_155 GGRVELGLGAGWFEEEHL-AYAIPFPPLGERFDRLTEQLQILTGMWGTPV
TH_2824|M.thermoresistible__bu GGRVEFGLGSGWFEPEHQ-AYAIPFPPLGERFDRLTEQLEIITGLWTTPS
MMAR_2729|M.marinum_M AGRAVLGIGAGWFELEHR-QLGYEFGTFTDRFNRLEEALQILDPMIK---
MUL_3024|M.ulcerans_Agy99 AGRAVLGIGAGWFELEHR-QLGYEFGTFTDRFNRLEEALQILDPIIK---
MAB_4797|M.abscessus_ATCC_1997 GGRLELGLGAGWNEEESQ-AYGIELGTLAERFDRFEEACHIITGLLS---
MAV_0986|M.avium_104 GGRIQMGIGAGWYEHEWR-AYGYGFPSAGVRLGRLDEGVQIMRDAWR---
MLBr_00269|M.leprae_Br4923 PNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWR---
.* :*:*:* * * : * .::
Mflv_4098|M.gilvum_PYR-GCK DERVDFAGRHFTVTDFPIKPGPVQKSGPPIVVGGVGEKYTLPLVARYADV
Mvan_2247|M.vanbaalenii_PYR-1 DERIDFTGKHFTVTDMPIKPGPVQRPRPPIVVGGVGEKFTLPLVARYADV
Mb0815c|M.bovis_AF2122/97 P---TYAGRFYTLDGATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQG
Rv0791c|M.tuberculosis_H37Rv P---TYAGRFYTLDGATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQG
MSMEG_0702|M.smegmatis_MC2_155 GDTFDFAGTHYTVKDSPGLPKPVQTPHPPIIIGGQGAKRTPALAAQFASE
TH_2824|M.thermoresistible__bu GEKYDFTGKHYTVVDSPGLPKPVQDPYPPIIIGGQGPKRTPALAARFANE
MMAR_2729|M.marinum_M GERPTFSGSWYQAESAMAEPRYRDR--IPILIGGGGEKKTFRIAAHWADH
MUL_3024|M.ulcerans_Agy99 GERPTFSGSWYQAESAMAEPRYRDR--IPILIGGGGEKKTFRIAAHWADH
MAB_4797|M.abscessus_ATCC_1997 QPRTSFSGQYYSVTDAYCEPKCLQQPYPPILIGGKGEKRTLPLVARYAQH
MAV_0986|M.avium_104 DGKVSFNGRHYQVDGAIVAPKPLQDNGIPLWIAGGGEKVTLRIAAEYAQY
MLBr_00269|M.leprae_Br4923 GDRVDFDGDYYQLKGASIYD--VPEGGVPIYIAAGG-PEVAKYAGRAGEG
: * : . *: :.. * . ... ..
Mflv_4098|M.gilvum_PYR-GCK WNVPTYALDQIEPK--IAVLRSICEDIGRDPDSIVLSIEAVMAVAPDQES
Mvan_2247|M.vanbaalenii_PYR-1 WNVPTYALGQIKEK--IAALRSICEDVGRDPQTITLSIEAVMALAPDEAS
Mb0815c|M.bovis_AF2122/97 LNVRWWSPQQVTQR--RGFLTQASEAAGRDPDTLRLSVTLLLAP----TQ
Rv0791c|M.tuberculosis_H37Rv LNVRWWSPQQVTQR--RGFLTQASEAAGRDPDTLRLSVTLLLAP----TQ
MSMEG_0702|M.smegmatis_MC2_155 FNIPFVPLDTLKTQ--FERVAAAVEGAGRSADSMIYSAAFVLCAGADEAQ
TH_2824|M.thermoresistible__bu FNIPFVRLDALKAQ--FERVAAAVAEAGREPDSMIYSAAFVLCAGRDDAE
MMAR_2729|M.marinum_M LNIVA-ALDELPRK--MDAVAARCEEAGRDPSTLETSVMLTVVVDEK---
MUL_3024|M.ulcerans_Agy99 LNIVA-ALDELPRK--MDAVAARCEEAGRDPSTLETSVMLTVVVDAK---
MAB_4797|M.abscessus_ATCC_1997 WNFPDGTPTEFARK--REILHAYCAAINRAPSAILTSAHVWLTSDTP---
MAV_0986|M.avium_104 TNFTP-ESAAFAHK--SEVLAAHCRDVGTDFDAIVRSVNVNAVVGASRAD
MLBr_00269|M.leprae_Br4923 FVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQ
. . : . . :
Mflv_4098|M.gilvum_PYR-GCK LESV-------------RMLAEKRFRGPGFG--------LHDTGLIGTPA
Mvan_2247|M.vanbaalenii_PYR-1 LPTV-------------RSLAEKRFGGEGFG--------LHDTDLIGTPA
Mb0815c|M.bovis_AF2122/97 SGEE-------------EVRIREEFASIPE-----------PGLIVGTPD
Rv0791c|M.tuberculosis_H37Rv SGEE-------------EVRIREEFASIPE-----------PGLIVGTPD
MSMEG_0702|M.smegmatis_MC2_155 IAKR-------------AAAIGREVDELRS-----------NSPLVGTST
TH_2824|M.thermoresistible__bu IARR-------------AAAINREVDELRS-----------NSPVVGTPA
MMAR_2729|M.marinum_M ------------------AKVERLPAETSR-----------RMVTGSPAQ
MUL_3024|M.ulcerans_Agy99 ------------------AKVERLPAETSR-----------RMVTGSPAQ
MAB_4797|M.abscessus_ATCC_1997 ------------------EGISRLVEELAA-----------FQTAG----
MAV_0986|M.avium_104 VDDRLRRIRDRMAGYVGESAADAMIAGTSG-----------VDSATGTTE
MLBr_00269|M.leprae_Br4923 ALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPD
Mflv_4098|M.gilvum_PYR-GCK EIAAKLGRLVEIGFGQIVLFTHDRCSDQTLELLASEIIPRL-------
Mvan_2247|M.vanbaalenii_PYR-1 EMVDRLGALAEMGFGQIVLFTHDRCSDQTLELLAAEVIPRL-------
Mb0815c|M.bovis_AF2122/97 RCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Rv0791c|M.tuberculosis_H37Rv RCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
MSMEG_0702|M.smegmatis_MC2_155 EIVDKLGPFIEAGVQRVYLQVLDMSDLDHVEFFANEVVRQFS------
TH_2824|M.thermoresistible__bu EIVDRLGPFIEAGVQRVYLQLLDMSDLDHLELIATQVVPQLR------
MMAR_2729|M.marinum_M IADQVQTKVLDTGIDGVIMNLSAHGHSPGLITTVAEALRPLLTG----
MUL_3024|M.ulcerans_Agy99 IADQVQTKVLDTGIDGVIMNLSAHGHSPGLITTVAEALRPLLTG----
MAB_4797|M.abscessus_ATCC_1997 -------------LDAAVIYLPVP-LDPRVLNPLANALNGLTAPPKR-
MAV_0986|M.avium_104 QVIERLARLRDLGCDYVICYFPEAAYDRSGIELFEREIIPALS-----
MLBr_00269|M.leprae_Br4923 EAVARVGQYVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG---