For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SRPEIGVYLPQMGFSFDELLHRARRCEKLGIDSLWLYDHLYGPGMPDYPSMEAWTLATALLSRTDTLRVG HMVLCNQFRHPVTLAKMATTLDQISGGRLSLGIGSGSIEDEHRRAGLPWGSFAERSEQLGETLQILHQAF GDERIDFTGKHFTVTDMPIKPGPVQRPRPPIVVGGVGEKFTLPLVARYADVWNVPTYALGQIKEKIAALR SICEDVGRDPQTITLSIEAVMALAPDEASLPTVRSLAEKRFGGEGFGLHDTDLIGTPAEMVDRLGALAEM GFGQIVLFTHDRCSDQTLELLAAEVIPRL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2247 | - | - | 100% (310) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_0629 | - | 4e-43 | 33.33% (315) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_3077 | - | 1e-37 | 39.65% (227) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 3e-39 | 30.37% (326) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_4098 | - | 1e-157 | 85.48% (310) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 3e-39 | 30.37% (326) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00269 | - | 3e-12 | 24.05% (341) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2431c | - | 3e-39 | 35.05% (291) | luciferase-like oxidoreductase |
| M. marinum M | MMAR_2729 | - | 6e-39 | 34.41% (279) | oxidoreductase |
| M. avium 104 | MAV_2865 | - | 1e-38 | 34.05% (279) | hypothetical protein MAV_2865 |
| M. smegmatis MC2 155 | MSMEG_0702 | - | 4e-42 | 34.21% (304) | monooxygenase |
| M. thermoresistible (build 8) | TH_2824 | - | 5e-46 | 34.97% (306) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3024 | - | 1e-38 | 38.79% (232) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2247|M.vanbaalenii_PYR-1 ---------MSRPEIGVYLPQMGFSFDELLHRARRCEKLGIDSLWLYDHL
Mflv_4098|M.gilvum_PYR-GCK ---------MRRPEIGVYLPQMGFSFDEVLHRARRCEDLGIDSLWLYDHL
MMAR_2729|M.marinum_M ----MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHF
MUL_3024|M.ulcerans_Agy99 ----MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHF
MAV_2865|M.avium_104 ----MAIRLGLQIPNFSYGTGAEQLFPTVIAQAREAESAGFDSVFVMDHF
MAB_2431c|M.abscessus_ATCC_199 ----MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHF
Mb0815c|M.bovis_AF2122/97 MNAKDDPHFGLMLAATVNGL-AVGSYREMVVVSQTAEEYGFDSVWLCDHF
Rv0791c|M.tuberculosis_H37Rv MNAKDDPHFGLMLAATVNGL-AVGSYREMVVVSQTAEEYGFDSVWLCDHF
MSMEG_0702|M.smegmatis_MC2_155 ----------MDFRVFVEPQ-QGATYSDQLAVAQAAERLGYSAFFRSDHY
TH_2824|M.thermoresistible__bu ----------MDFRVFVEPQ-QGGTYADQLAVARAAEDLGYSAFFRSDHY
MLBr_00269|M.leprae_Br4923 ---------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHF
: .* * .: **
Mvan_2247|M.vanbaalenii_PYR-1 YGPG--------------------------MPDYP----SMEAWTLATAL
Mflv_4098|M.gilvum_PYR-GCK YGPG--------------------------MPDYP----SMEAWTLATAL
MMAR_2729|M.marinum_M YQLP-----------------------MLGTPDQP----MLEAYTALGAL
MUL_3024|M.ulcerans_Agy99 YQLP-----------------------MLGTPDQP----MLEAYTALGAL
MAV_2865|M.avium_104 YQLP-----------------------MLGSPDQP----MLEAYTALGAL
MAB_2431c|M.abscessus_ATCC_199 YQLP-----------------------MIGTPDQP----MLEAYTALGAL
Mb0815c|M.bovis_AF2122/97 LTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAAL
Rv0791c|M.tuberculosis_H37Rv LTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAAL
MSMEG_0702|M.smegmatis_MC2_155 LKMA-----------------------GDGLPGPT------DSWVTLAGI
TH_2824|M.thermoresistible__bu LAMS-----------------------GDGLPGPT------DSWVTLAGI
MLBr_00269|M.leprae_Br4923 QPWR----------------------HQGGHASFS--------LSWMTAV
. .:
Mvan_2247|M.vanbaalenii_PYR-1 LSRTDTLRVGHMVLCNQFRH-PVTLAKMATTLDQISGGRLSLGIGSGS-I
Mflv_4098|M.gilvum_PYR-GCK LSRTERLRIGHMVLCNQFRH-PVTLAKMVTTLDQISGGRLSLGIGSGS-I
MMAR_2729|M.marinum_M ATATERLQLGTLVTGNTYRN-PALLAKIITTLDVVSAGRAVLGIGAGW-F
MUL_3024|M.ulcerans_Agy99 ATATERLQLGTLVTGNTYRN-PALLAKIITTLDVVSAGRAVLGIGAGW-F
MAV_2865|M.avium_104 ATATERVQLGTLVTGNTYRN-PTLLAKIITTLDVVSQGRAILGIGTGW-F
MAB_2431c|M.abscessus_ATCC_199 ASATSTIQLSTLVTGNTYRN-PALLAKAVTTLDVVSGGRAILGIGAGW-F
Mb0815c|M.bovis_AF2122/97 SRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVISQGRLDLGLGAGW-F
Rv0791c|M.tuberculosis_H37Rv SRDTTKLRLGTSVLCNSYRH-PSVLAKMAATLDVISQGRLDLGLGAGW-F
MSMEG_0702|M.smegmatis_MC2_155 ARETSTIRLGTMVTSATFRY-PGPLAISVAQVDEMSGGRVELGLGAGW-F
TH_2824|M.thermoresistible__bu ARETTSIRLGTLVTSATFRY-PGPLAISVAQVDEMSGGRVEFGLGSGW-F
MLBr_00269|M.leprae_Br4923 GERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYPNRVFLGVGTGEAL
* : :. * :* * :. : :. : .* :*:*:* :
Mvan_2247|M.vanbaalenii_PYR-1 EDEHRRAGLPWGSFAERSEQLGETLQILHQAFGDERI---DFTGKHFTVT
Mflv_4098|M.gilvum_PYR-GCK EDEHRRAGLPWGTFAERSAQLGETLQILRQAFTDERV---DFAGRHFTVT
MMAR_2729|M.marinum_M ELEHRQLGYEFGTFTDRFNRLEEALQILDPMIKGERP---TFSGSWYQAE
MUL_3024|M.ulcerans_Agy99 ELEHRQLGYEFGTFTDRFNRLEEALQILDPIIKGERP---TFSGSWYQAE
MAV_2865|M.avium_104 QLEHDQLGFEFGTFTDRFNRLDEALEIILPMIRGERA---TFEGKWYRAS
MAB_2431c|M.abscessus_ATCC_199 ELEHQQLGFEFGTFTDRFERLTEALEIIPPMLRGERP---TFEGKYYRTE
Mb0815c|M.bovis_AF2122/97 RRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNP---TYAGRFYTLD
Rv0791c|M.tuberculosis_H37Rv RRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNP---TYAGRFYTLD
MSMEG_0702|M.smegmatis_MC2_155 EEEHLAYAIPFPPLGERFDRLTEQLQILTGMWGTPVGDTFDFAGTHYTVK
TH_2824|M.thermoresistible__bu EPEHQAYAIPFPPLGERFDRLTEQLEIITGLWTTPSGEKYDFTGKHYTVV
MLBr_00269|M.leprae_Br4923 NEVATGYQGAWPEFKERFARLRESVRLMRELWRGDRV---DFDGDYYQLK
. : . :* * * :.:: : * :
Mvan_2247|M.vanbaalenii_PYR-1 DMPIKPGPVQRPRPPIVVGGVGEKFTLPLVARYADVWNVPTYALGQIKEK
Mflv_4098|M.gilvum_PYR-GCK DFPIKPGPVQKSGPPIVVGGVGEKYTLPLVARYADVWNVPTYALDQIEPK
MMAR_2729|M.marinum_M SAMAEPR--YRDRIPILIGGGGEKKTFRIAAHWADHLNIVAA-LDELPRK
MUL_3024|M.ulcerans_Agy99 SAMAEPR--YRDRIPILIGGGGEKKTFRIAAHWADHLNIVAA-LDELPRK
MAV_2865|M.avium_104 DAFANPR--YRDRIPLMIGGSGEKKTIPLAARHFDHLNVIAG-FDELPRK
MAB_2431c|M.abscessus_ATCC_199 SALNEPR--LRPNIPIMIGGSGEKKTFGLAVKYADHLNLLSS-LDEIPHK
Mb0815c|M.bovis_AF2122/97 GATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQGLNVRWWSPQQVTQR
Rv0791c|M.tuberculosis_H37Rv GATCDPPPVQRPHPPLWIGGEG-DRVQRIAAKHAQGLNVRWWSPQQVTQR
MSMEG_0702|M.smegmatis_MC2_155 DSPGLPKPVQTPHPPIIIGGQGAKRTPALAAQFASEFNIPFVPLDTLKTQ
TH_2824|M.thermoresistible__bu DSPGLPKPVQDPYPPIIIGGQGPKRTPALAARFANEFNIPFVRLDALKAQ
MLBr_00269|M.leprae_Br4923 GASIYDVP--EGGVPIYIAAGG-PEVAKYAGRAGEGFVCTSGKGEELYTE
. *: :.. * . . : . : .
Mvan_2247|M.vanbaalenii_PYR-1 --IAALRSICEDVGRDPQTITLSIEAVMALAPDEASLPTVR---------
Mflv_4098|M.gilvum_PYR-GCK --IAVLRSICEDIGRDPDSIVLSIEAVMAVAPDQESLESVR---------
MMAR_2729|M.marinum_M --MDAVAARCEEAGRDPSTLETSVMLTVVVDEKAK---------------
MUL_3024|M.ulcerans_Agy99 --MDAVAARCEEAGRDPSTLETSVMLTVVVDAKAK---------------
MAV_2865|M.avium_104 --LDAVRRACEQVGRDPATLETSTLTTVMIDDNAS---------------
MAB_2431c|M.abscessus_ATCC_199 --LTVLRQRCEEAGRDPSTLETSAFFSVFIDDDSATAWKLAASQL-----
Mb0815c|M.bovis_AF2122/97 --RGFLTQASEAAGRDPDTLRLSVTLLLAP----TQSGE-----------
Rv0791c|M.tuberculosis_H37Rv --RGFLTQASEAAGRDPDTLRLSVTLLLAP----TQSGE-----------
MSMEG_0702|M.smegmatis_MC2_155 --FERVAAAVEGAGRSADSMIYSAAFVLCAGADEAQIAK-----------
TH_2824|M.thermoresistible__bu --FERVAAAVAEAGREPDSMIYSAAFVLCAGRDDAEIAR-----------
MLBr_00269|M.leprae_Br4923 KLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQALSNIRFWAPLSLA
: **.. : :
Mvan_2247|M.vanbaalenii_PYR-1 ----------SLAEKRFGGEGFGLHDT--DLIGTPAEMVDRLG-ALAEMG
Mflv_4098|M.gilvum_PYR-GCK ----------MLAEKRFRGPGFGLHDT--GLIGTPAEIAAKLG-RLVEIG
MMAR_2729|M.marinum_M ------------VERLP----AETSRR--MVTGSPAQIADQVQTKVLDTG
MUL_3024|M.ulcerans_Agy99 ------------VERLP----AETSRR--MVTGSPAQIADQVQTKVLDTG
MAV_2865|M.avium_104 ------------LDQIP----AEMTQR--MVVGNPDSVADQIKTKVIDAG
MAB_2431c|M.abscessus_ATCC_199 ------SQNGIDLDTLPDEARAQVLGR--TLVGNPEEIAEQVQTRVLDQG
Mb0815c|M.bovis_AF2122/97 -----------EEVRIREEFASIPEPG--LIVGTPDRCVERIR-EYQDRG
Rv0791c|M.tuberculosis_H37Rv -----------EEVRIREEFASIPEPG--LIVGTPDRCVERIR-EYQDRG
MSMEG_0702|M.smegmatis_MC2_155 -----------RAAAIGREVDELRSNS--PLVGTSTEIVDKLG-PFIEAG
TH_2824|M.thermoresistible__bu -----------RAAAINREVDELRSNS--PVVGTPAEIVDRLG-PFIEAG
MLBr_00269|M.leprae_Br4923 AEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSDPDEAVARVG-QYVTWG
: . . . :: *
Mvan_2247|M.vanbaalenii_PYR-1 FGQIVLFTHDRCSDQTLELLAAEVIPRL-------
Mflv_4098|M.gilvum_PYR-GCK FGQIVLFTHDRCSDQTLELLASEIIPRL-------
MMAR_2729|M.marinum_M IDGVIMNLSAHGHSPGLITTVAEALRPLLTG----
MUL_3024|M.ulcerans_Agy99 IDGVIMNLSAHGHSPGLITTVAEALRPLLTG----
MAV_2865|M.avium_104 IDSVIINLPFY--TPGIVQAAGEALRPLVGA----
MAB_2431c|M.abscessus_ATCC_199 IDSVTLNAPATGHLPGVVELIGNTLRPLFKN----
Mb0815c|M.bovis_AF2122/97 VGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
Rv0791c|M.tuberculosis_H37Rv VGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP
MSMEG_0702|M.smegmatis_MC2_155 VQRVYLQVLDMSDLDHVEFFANEVVRQFS------
TH_2824|M.thermoresistible__bu VQRVYLQLLDMSDLDHLELIATQVVPQLR------
MLBr_00269|M.leprae_Br4923 LNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG---
. . : : : .