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IEWFLFLPQLRLAVSEFVQRAMCAEDAGFDGVAFIDHLEAPGQRDESIWEAMSIATWVAAKTSRLRVGHL VLCDAFRHPAVLAKEAVTLSAASGGRFELGLGAGSWPVDFTRFEVGQQNPVDRVRQLERDLRLIMRYWGD TDEAQRPRPWYPIPLLLGGSGPRMMRLVAQYADWWNLQANQLDRLPRLASSVGSARISVQQMVGFVRSGE DSASVREVSTRRFAHLGTGLVCGGAGEMIEHFAGLAAQGVQRFYVWFADFAAADTLAEFGESAIKEFADP R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3839 | - | - | 100% (282) | coenzyme F420-dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_3202 | - | 2e-22 | 29.91% (321) | oxidoreductase |
| M. ulcerans Agy99 | MUL_3024 | - | 1e-17 | 33.16% (193) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 5e-21 | 27.59% (319) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_4098 | - | 1e-30 | 31.51% (292) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0791c | - | 5e-21 | 27.59% (319) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00348 | - | 6e-08 | 27.68% (177) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0968c | - | 2e-18 | 35.90% (156) | luciferase-like hypothetical protein |
| M. marinum M | MMAR_3978 | - | 1e-160 | 97.87% (282) | coenzyme F420-dependent oxidoreductase |
| M. avium 104 | MAV_1632 | - | 1e-117 | 71.79% (280) | hypothetical protein MAV_1632 |
| M. smegmatis MC2 155 | MSMEG_2996 | - | 1e-103 | 64.49% (276) | hypothetical protein MSMEG_2996 |
| M. thermoresistible (build 8) | TH_0538 | - | 1e-101 | 64.16% (279) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_2247 | - | 1e-32 | 31.76% (296) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0815c|M.bovis_AF2122/97 -MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHF
Rv0791c|M.tuberculosis_H37Rv -MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHF
MUL_3839|M.ulcerans_Agy99 ------MIEWFLFLPQLR-----LAVSEFVQRAMCAEDAGFDGVAFIDHL
MMAR_3978|M.marinum_M ------MIEWFLFLPQLR-----LAVPEFVQRAMCAEDAGFDGVAFIDHL
MAV_1632|M.avium_104 ------MVEWYLFLPQVR-----LSAADIAERARRAEASGFDGIVFIDHL
MSMEG_2996|M.smegmatis_MC2_155 ------MTEWFLFLPQVR-----LEIGDIVERARIAEAAGFDGIAFIDHL
TH_0538|M.thermoresistible__bu ------VAEWFLFLPQVR-----FRLAEIVERARVAETSGFDGIAFIDHL
Mflv_4098|M.gilvum_PYR-GCK ----MRRPEIGVYLPQMG-----FSFDEVLHRARRCEDLGIDSLWLYDHL
Mvan_2247|M.vanbaalenii_PYR-1 ----MSRPEIGVYLPQMG-----FSFDELLHRARRCEKLGIDSLWLYDHL
MAB_0968c|M.abscessus_ATCC_199 -------MRFSIWGQTNQ------SWADLLDIAQYADDGTWRAFYAADHF
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQ----PPGNAAELVAAAEGAGFDAVFTGEAW
. : : .: .. :
Mb0815c|M.bovis_AF2122/97 LTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAAL
Rv0791c|M.tuberculosis_H37Rv LTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAAL
MUL_3839|M.ulcerans_Agy99 EAPG------------------------------QRDESIWEAMSIATWV
MMAR_3978|M.marinum_M EAPG------------------------------QRDESIWEAMSIATWV
MAV_1632|M.avium_104 EAPG------------------------------LRDENIWEAMGIATWV
MSMEG_2996|M.smegmatis_MC2_155 EAPG------------------------------ATHQGIWEAMTTATWV
TH_0538|M.thermoresistible__bu EAPG------------------------------ATHQGIWEAMTVATWV
Mflv_4098|M.gilvum_PYR-GCK YGPG------------------------------MPDYPSMEAWTLATAL
Mvan_2247|M.vanbaalenii_PYR-1 YGPG------------------------------MPDYPSMEAWTLATAL
MAB_0968c|M.abscessus_ATCC_199 MSHADT---------------------------AEERTDFHEATALFAAL
MLBr_00348|M.leprae_Br4923 GSDA---------------------------------------YTPLAWW
. :
Mb0815c|M.bovis_AF2122/97 SRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRR
Rv0791c|M.tuberculosis_H37Rv SRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRR
MUL_3839|M.ulcerans_Agy99 AAKTSRLRVGHLVLCDAFRHPAVLAKEAVTLSAASGGRFELGLGAGSWPV
MMAR_3978|M.marinum_M AAKTSRLRVGHLVLCDAFRHPAVLAKQAVTLSAASGGRFELGLGAGSWPV
MAV_1632|M.avium_104 AAKTERLRIGHLVLCDAFRHPAVLAKQAVTLSEASEGRFELGLGAGSWPA
MSMEG_2996|M.smegmatis_MC2_155 AAHTERLRIGHLVLCDAFRHPAVLAKQAVTLSTASDGRFELGLGSGSWPQ
TH_0538|M.thermoresistible__bu AAHTERLRIGHLVLCDAFRHPAVLAKQAVTLAAATGGRFELGLGWGSWPQ
Mflv_4098|M.gilvum_PYR-GCK LSRTERLRIGHMVLCNQFRHPVTLAKMVTTLDQISGGRLSLGIGSGSIED
Mvan_2247|M.vanbaalenii_PYR-1 LSRTDTLRVGHMVLCNQFRHPVTLAKMATTLDQISGGRLSLGIGSGSIED
MAB_0968c|M.abscessus_ATCC_199 AAATSRIRLAPLVLSMTFRHPAVLANWAATVDHVSQGRFTLGLGAGWQEN
MLBr_00348|M.leprae_Br4923 GSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQV
* :*:. *: * * . * . *: : ** **:* .
Mb0815c|M.bovis_AF2122/97 ESQAYGIPF-PPVGDR-------VSALAESLQVIKAVWTEPNPTYAGRFY
Rv0791c|M.tuberculosis_H37Rv ESQAYGIPF-PPVGDR-------VSALAESLQVIKAVWTEPNPTYAGRFY
MUL_3839|M.ulcerans_Agy99 DFTRFEVGQ-QNPVDR-------VRQLERDLRLIMRYWGDT--DE-----
MMAR_3978|M.marinum_M EFTRFEVGQ-QNPVDR-------VRQLERDLRLIMRYWGDT--DE-----
MAV_1632|M.avium_104 EFARFDVGQ-QDPKAR-------VAQLARHLELIKRYWGDDGRGE-----
MSMEG_2996|M.smegmatis_MC2_155 EFFRFGVDGGDDAAAR-------VDRLERDLALLREHWGEGERG------
TH_0538|M.thermoresistible__bu EFDRFGIDDGHDAPAR-------VRRLARTLELLPRYWGADDHDDL----
Mflv_4098|M.gilvum_PYR-GCK EHRRAGLPW-GTFAER-------SAQLGETLQILRQAFTDERVDFAGRHF
Mvan_2247|M.vanbaalenii_PYR-1 EHRRAGLPW-GSFAER-------SEQLGETLQILHQAFGDERIDFTGKHF
MAB_0968c|M.abscessus_ATCC_199 EHQRYGLEL-GKPGAR-------VDRFSEGLQVITGLLNEPVTTVDGQYY
MLBr_00348|M.leprae_Br4923 VEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGAT
. ::
Mb0815c|M.bovis_AF2122/97 TLDGATCDPPPVQRPHPPLWIGGEGDR-VQRIAAKHAQGLNVRWWSPQQV
Rv0791c|M.tuberculosis_H37Rv TLDGATCDPPPVQRPHPPLWIGGEGDR-VQRIAAKHAQGLNVRWWSPQQV
MUL_3839|M.ulcerans_Agy99 -------AQRPRPWYPIPLLLGGSGPR-MMRLVAQYADWWNLQANQLDRL
MMAR_3978|M.marinum_M -------AQRPRPLYPIPLLLGGSGPR-MMRLVAQYADWWNLQANQLDRL
MAV_1632|M.avium_104 -------AQAPRRSHPIPLVLGGSGPR-MMELVRTHADWWNLPANKLDKL
MSMEG_2996|M.smegmatis_MC2_155 --------QVPAPAHKIPLVIGGTGRR-TMGLVRRYADWWNIPSHQLDRL
TH_0538|M.thermoresistible__bu -------VQQPVPEHPIPLVLGGTGKR-TMELVRQYAHWWNVPSHQLDRL
Mflv_4098|M.gilvum_PYR-GCK TVTDFPIKPGPVQKSGPPIVVGGVGEKYTLPLVARYADVWNVPTYALDQI
Mvan_2247|M.vanbaalenii_PYR-1 TVTDMPIKPGPVQRPRPPIVVGGVGEKFTLPLVARYADVWNVPTYALGQI
MAB_0968c|M.abscessus_ATCC_199 RLAEGICEPKPLQR-PLPILIGATQPR-MLALTARYAHEWN-QWSSPGTF
MLBr_00348|M.leprae_Br4923 GLGKALKPITHPLRADIPIMLGAEGPK-NVALAAEICDGWLPIFFSPRMA
*: :*. : :. ..
Mb0815c|M.bovis_AF2122/97 TQRRGFLTQ--ASEAAGRDPDTLRLSVTLLLAPTQSGEEEVR--------
Rv0791c|M.tuberculosis_H37Rv TQRRGFLTQ--ASEAAGRDPDTLRLSVTLLLAPTQSGEEEVR--------
MUL_3839|M.ulcerans_Agy99 PRLASSVG-------------SARISVQQMVGFVRSGEDSAS--------
MMAR_3978|M.marinum_M PRLASSVG-------------SARISVQQMVGFVRSGEDPAS--------
MAV_1632|M.avium_104 PALAPAAG-------------SARLSIQQMVGFVRAGQDPEK--------
MSMEG_2996|M.smegmatis_MC2_155 PDLLPTVG-------------AARASMQQMVGFVGRGIDRAA--------
TH_0538|M.thermoresistible__bu PELLPTIG-------------SARASVQQMVGFVGEDADRDA--------
Mflv_4098|M.gilvum_PYR-GCK EPKIAVLRS--ICEDIGRDPDSIVLSIEAVMAVAPDQESLES--------
Mvan_2247|M.vanbaalenii_PYR-1 KEKIAALRS--ICEDVGRDPQTITLSIEAVMALAPDEASLPT--------
MAB_0968c|M.abscessus_ATCC_199 REVSGRLDA--AAEKIGRDPATIWRSTQARVIVTDGPQSEAR--------
MLBr_00348|M.leprae_Br4923 DMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFAGIKPFLAL
. : .
Mb0815c|M.bovis_AF2122/97 ----------------IREEFAS---IPEPGL----IVGTPDRCVERIRE
Rv0791c|M.tuberculosis_H37Rv ----------------IREEFAS---IPEPGL----IVGTPDRCVERIRE
MUL_3839|M.ulcerans_Agy99 ----------------VREVSTRRFAHLGTGL----VCGGAGEMIEHFAG
MMAR_3978|M.marinum_M ----------------VREVSTRRFAHLGTGL----VCGGAGEMIEHFAG
MAV_1632|M.avium_104 ----------------VREVSTRRFGNLGSGL----VCGDADELIGHFSG
MSMEG_2996|M.smegmatis_MC2_155 ----------------VTERSSRLFGHLGSGL----VCGDAAELTEHFAG
TH_0538|M.thermoresistible__bu ----------------VTEVSRRRFGHLGDGL----RCGDAAELADHFGA
Mflv_4098|M.gilvum_PYR-GCK ----------------VRMLAEKRFRGPGFGLHDTGLIGTPAEIAAKLGR
Mvan_2247|M.vanbaalenii_PYR-1 ----------------VRSLAEKRFGGEGFGLHDTDLIGTPAEMVDRLGA
MAB_0968c|M.abscessus_ATCC_199 ----------------AAETAAASPIPVLYGT--------AERIAEQMAP
MLBr_00348|M.leprae_Br4923 YMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELV
. . . .
Mb0815c|M.bovis_AF2122/97 YQDRGVGHFLFTIPHVV----KSDYLHIIGSDIIPRVKTEVTIP-
Rv0791c|M.tuberculosis_H37Rv YQDRGVGHFLFTIPHVV----KSDYLHIIGSDIIPRVKTEVTIP-
MUL_3839|M.ulcerans_Agy99 LAAQGVQRFYVWFADFA----AADTLAEFGESAIKEFADPR----
MMAR_3978|M.marinum_M LAAQGVQRFYVWFADFA----AADTLAEFGESVIKEFADPR----
MAV_1632|M.avium_104 LAAQRVERFYVWFADFA----APDSLREFGESVITAFPAR-----
MSMEG_2996|M.smegmatis_MC2_155 LAAQGIERFYVWFADFA----APQTISEFAETVMHTGQKGTT---
TH_0538|M.thermoresistible__bu LAAQGVERFYVWFADFA----QPQTLAEFADTVIRAR--------
Mflv_4098|M.gilvum_PYR-GCK LVEIGFGQIVLFTHDRC----SDQTLELLASEIIPRL--------
Mvan_2247|M.vanbaalenii_PYR-1 LAEMGFGQIVLFTHDRC----SDQTLELLAAEVIPRL--------
MAB_0968c|M.abscessus_ATCC_199 WTQEGVDEVILPDHLLG----SGSARRDAYDALAQALRPLSNETD
MLBr_00348|M.leprae_Br4923 DSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF-
. .