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M. thermoresistible (build 8) TH_0538 (-)

annotation: conserved hypothetical protein
coordinates: 1155473 - 1156321
length: 283

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0538--100% (283)conserved hypothetical protein
M. thermoresistible (build 8)TH_2824-3e-1627.91% (301) PUTATIVE luciferase family protein
M. thermoresistible (build 8)TH_0517-2e-1531.74% (167) MmcI protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1886c-2e-1528.12% (256) oxidoreductase
M. gilvum PYR-GCKMflv_4098-4e-3633.89% (301) luciferase family protein
M. tuberculosis H37RvRv1855c-2e-1528.12% (256) oxidoreductase
M. leprae Br4923MLBr_00269-4e-0727.84% (176) putative F420-dependent glucose-6-phosphate dehydrogenase
M. abscessus ATCC 19977MAB_2431c-4e-1731.63% (196) luciferase-like oxidoreductase
M. marinum MMMAR_3978-1e-10265.23% (279) coenzyme F420-dependent oxidoreductase
M. avium 104MAV_1632-1e-10467.26% (281) hypothetical protein MAV_1632
M. smegmatis MC2 155MSMEG_2996-1e-12375.27% (279) hypothetical protein MSMEG_2996
M. ulcerans Agy99MUL_3839-1e-10164.16% (279) coenzyme F420-dependent oxidoreductase
M. vanbaalenii PYR-1Mvan_2247-5e-4034.22% (301) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1886c|M.bovis_AF2122/97           MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLP
Rv1855c|M.tuberculosis_H37Rv        MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLP
MAB_2431c|M.abscessus_ATCC_199      MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLP
TH_0538|M.thermoresistible__bu      -------VAEWFLFLPQVRFRLAEIVERARVAETSGFDGIAFIDHLEAP-
MSMEG_2996|M.smegmatis_MC2_155      -------MTEWFLFLPQVRLEIGDIVERARIAEAAGFDGIAFIDHLEAP-
MMAR_3978|M.marinum_M               -------MIEWFLFLPQLRLAVPEFVQRAMCAEDAGFDGVAFIDHLEAP-
MUL_3839|M.ulcerans_Agy99           -------MIEWFLFLPQLRLAVSEFVQRAMCAEDAGFDGVAFIDHLEAP-
MAV_1632|M.avium_104                -------MVEWYLFLPQVRLSAADIAERARRAEASGFDGIVFIDHLEAP-
Mflv_4098|M.gilvum_PYR-GCK          -----MRRPEIGVYLPQMGFSFDEVLHRARRCEDLGIDSLWLYDHLYGP-
Mvan_2247|M.vanbaalenii_PYR-1       -----MSRPEIGVYLPQMGFSFDELLHRARRCEKLGIDSLWLYDHLYGP-
MLBr_00269|M.leprae_Br4923          -----MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATVSDHFQPWR
                                                   .        .      .*  * *   . **:    

Mb1886c|M.bovis_AF2122/97           MLGTPDQPMLEAYTALGALATATERLQLGALVTGNTYRS-PTLLAKIITT
Rv1855c|M.tuberculosis_H37Rv        MLGTPDQPMLEAYTALGALATATERLQLGALVTGNTYRS-PTLLAKIITT
MAB_2431c|M.abscessus_ATCC_199      MIGTPDQPMLEAYTALGALASATSTIQLSTLVTGNTYRN-PALLAKAVTT
TH_0538|M.thermoresistible__bu      --GATHQGIWEAMTVATWVAAHTERLRIGHLVLCDAFRH-PAVLAKQAVT
MSMEG_2996|M.smegmatis_MC2_155      --GATHQGIWEAMTTATWVAAHTERLRIGHLVLCDAFRH-PAVLAKQAVT
MMAR_3978|M.marinum_M               --GQRDESIWEAMSIATWVAAKTSRLRVGHLVLCDAFRH-PAVLAKQAVT
MUL_3839|M.ulcerans_Agy99           --GQRDESIWEAMSIATWVAAKTSRLRVGHLVLCDAFRH-PAVLAKEAVT
MAV_1632|M.avium_104                --GLRDENIWEAMGIATWVAAKTERLRIGHLVLCDAFRH-PAVLAKQAVT
Mflv_4098|M.gilvum_PYR-GCK          --GMPDYPSMEAWTLATALLSRTERLRIGHMVLCNQFRH-PVTLAKMVTT
Mvan_2247|M.vanbaalenii_PYR-1       --GMPDYPSMEAWTLATALLSRTDTLRVGHMVLCNQFRH-PVTLAKMATT
MLBr_00269|M.leprae_Br4923          ---HQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFAT
                                               :      :   *. : :.  *    :*  *. :.:  .*

Mb1886c|M.bovis_AF2122/97           LDVVSAGRAILGIGAGWFELEHRQLGFEF-GTFSDRFNRLEEALQILEPM
Rv1855c|M.tuberculosis_H37Rv        LDVVSAGRAILGIGAGWFELEHRQLGFEF-GTFSDRFNRLEEALQILEPM
MAB_2431c|M.abscessus_ATCC_199      LDVVSGGRAILGIGAGWFELEHQQLGFEF-GTFTDRFERLTEALEIIPPM
TH_0538|M.thermoresistible__bu      LAAATGGRFELGLGWGSWPQEFDRFGIDDGHDAPARVRRLARTLELLPRY
MSMEG_2996|M.smegmatis_MC2_155      LSTASDGRFELGLGSGSWPQEFFRFGVDGGDDAAARVDRLERDLALLREH
MMAR_3978|M.marinum_M               LSAASGGRFELGLGAGSWPVEFTRFEVGQ-QNPVDRVRQLERDLRLIMRY
MUL_3839|M.ulcerans_Agy99           LSAASGGRFELGLGAGSWPVDFTRFEVGQ-QNPVDRVRQLERDLRLIMRY
MAV_1632|M.avium_104                LSEASEGRFELGLGAGSWPAEFARFDVGQ-QDPKARVAQLARHLELIKRY
Mflv_4098|M.gilvum_PYR-GCK          LDQISGGRLSLGIGSGSIEDEHRRAGLPW-GTFAERSAQLGETLQILRQA
Mvan_2247|M.vanbaalenii_PYR-1       LDQISGGRLSLGIGSGSIEDEHRRAGLPW-GSFAERSEQLGETLQILHQA
MLBr_00269|M.leprae_Br4923          MGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMREL
                                    :     .*  **:* *    :              *  :* . : ::   

Mb1886c|M.bovis_AF2122/97           VKGERPTFFG--DWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFA
Rv1855c|M.tuberculosis_H37Rv        VKGERPTFFG--DWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFA
MAB_2431c|M.abscessus_ATCC_199      LRGERPTFEG--KYYRTESALNEPRLRPNIPIMIGGSGEKKTFGLAVKYA
TH_0538|M.thermoresistible__bu      WGADDHDDL-----------VQQPVPEHPIPLVLGGTGKR-TMELVRQYA
MSMEG_2996|M.smegmatis_MC2_155      WGEGERG--------------QVPAPAHKIPLVIGGTGRR-TMGLVRRYA
MMAR_3978|M.marinum_M               WGDT--DE------------AQRPRPLYPIPLLLGGSGPR-MMRLVAQYA
MUL_3839|M.ulcerans_Agy99           WGDT--DE------------AQRPRPWYPIPLLLGGSGPR-MMRLVAQYA
MAV_1632|M.avium_104                WGDDGRGE------------AQAPRRSHPIPLVLGGSGPR-MMELVRTHA
Mflv_4098|M.gilvum_PYR-GCK          FTDERVDFAGRHFTVTDFPIKPGPVQKSGPPIVVGGVGEKYTLPLVARYA
Mvan_2247|M.vanbaalenii_PYR-1       FGDERIDFTGKHFTVTDMPIKPGPVQRPRPPIVVGGVGEKFTLPLVARYA
MLBr_00269|M.leprae_Br4923          WRGDRVDFDG--DYYQLKGASIYDVPEGGVPIYIAAGGPE-VAKYAGRAG
                                                                  *: :.. * .     .   .

Mb1886c|M.bovis_AF2122/97           DHLNIVA-AVDELP--RKMRALAARCDEAGRD--RSTLQTSLLLTVMIDE
Rv1855c|M.tuberculosis_H37Rv        DHLNIVA-AVDELP--RKMRALAARCDEAGRD--RSTLQTSLLLTVMIDE
MAB_2431c|M.abscessus_ATCC_199      DHLNLLS-SLDEIP--HKLTVLRQRCEEAGRD--PSTLETSAFFSVFIDD
TH_0538|M.thermoresistible__bu      HWWNVPSHQLDRLP--ELLPTIG-----------SARASVQQMVGFVGED
MSMEG_2996|M.smegmatis_MC2_155      DWWNIPSHQLDRLP--DLLPTVG-----------AARASMQQMVGFVGRG
MMAR_3978|M.marinum_M               DWWNLQANQLDRLP--RLASSVG-----------SARISVQQMVGFVRSG
MUL_3839|M.ulcerans_Agy99           DWWNLQANQLDRLP--RLASSVG-----------SARISVQQMVGFVRSG
MAV_1632|M.avium_104                DWWNLPANKLDKLP--ALAPAAG-----------SARLSIQQMVGFVRAG
Mflv_4098|M.gilvum_PYR-GCK          DVWNVPTYALDQIE--PKIAVLRSICEDIGRDPDSIVLSIEAVMAVAPDQ
Mvan_2247|M.vanbaalenii_PYR-1       DVWNVPTYALGQIK--EKIAALRSICEDVGRDPQTITLSIEAVMALAPDE
MLBr_00269|M.leprae_Br4923          EGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDP
                                    .     :    .:                           .  .      

Mb1886c|M.bovis_AF2122/97           T-----------LS---------PDAIPAEMSGR-----------VVVGS
Rv1855c|M.tuberculosis_H37Rv        T-----------LS---------PDAIPAEMSGR-----------VVVGS
MAB_2431c|M.abscessus_ATCC_199      DSATAWKLAASQLSQNGIDLDTLPDEARAQVLGR-----------TLVGN
TH_0538|M.thermoresistible__bu      ADRDA----VTEVS---------RRRFGHLGDGL------------RCGD
MSMEG_2996|M.smegmatis_MC2_155      IDRAA----VTERS---------SRLFGHLGSGL------------VCGD
MMAR_3978|M.marinum_M               EDPAS----VREVS---------TRRFAHLGTGL------------VCGG
MUL_3839|M.ulcerans_Agy99           EDSAS----VREVS---------TRRFAHLGTGL------------VCGG
MAV_1632|M.avium_104                QDPEK----VREVS---------TRRFGNLGSGL------------VCGD
Mflv_4098|M.gilvum_PYR-GCK          ESLES----VRMLA---------EKRFRGPGFGLHD--------TGLIGT
Mvan_2247|M.vanbaalenii_PYR-1       ASLPT----VRSLA---------EKRFGGEGFGLHD--------TDLIGT
MLBr_00269|M.leprae_Br4923          EQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAKRWIVVSD
                                                 :                  .               . 

Mb1886c|M.bovis_AF2122/97           PAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVITTAAEALRPLLGV--
Rv1855c|M.tuberculosis_H37Rv        PAQIADQIQAKVLDAGVDGLIINLAPHGYLPGVITTAAEALRPLLGV--
MAB_2431c|M.abscessus_ATCC_199      PEEIAEQVQTRVLDQGIDSVTLNAPATGHLPGVVELIGNTLRPLFKN--
TH_0538|M.thermoresistible__bu      AAELADHFGA-LAAQGVERFYVWFADFAQPQTLAEFADTVIRAR-----
MSMEG_2996|M.smegmatis_MC2_155      AAELTEHFAG-LAAQGIERFYVWFADFAAPQTISEFAETVMHTGQKGTT
MMAR_3978|M.marinum_M               AGEMIEHFAG-LAAQGVQRFYVWFADFAAADTLAEFGESVIKEFADPR-
MUL_3839|M.ulcerans_Agy99           AGEMIEHFAG-LAAQGVQRFYVWFADFAAADTLAEFGESAIKEFADPR-
MAV_1632|M.avium_104                ADELIGHFSG-LAAQRVERFYVWFADFAAPDSLREFGESVITAFPAR--
Mflv_4098|M.gilvum_PYR-GCK          PAEIAAKLGR-LVEIGFGQIVLFTHDRCSDQTLELLASEIIPRL-----
Mvan_2247|M.vanbaalenii_PYR-1       PAEMVDRLGA-LAEMGFGQIVLFTHDRCSDQTLELLAAEVIPRL-----
MLBr_00269|M.leprae_Br4923          PDEAVARVGQ-YVTWGLNHLVFHAPGHNQRRFLELFEKDLAPRLRRLG-
                                    . :   :.        .  . .          :