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DLGFHIPIFDIDGGTTAIAGELARVGESAEAAGASWLSFMDHFFQIEPTGLPAEAHMLEGYTTLGYLAAH TETVPLGLLVTGVTYRHPGLLAKIVTTLDVLSGGRAVLGVGAAWFEREHVGLGVPFPPLAERFERLEETL QICAQMWDPADNGPYDGKYYQLAETLCSPQPINRPKVMIGGSGERKTLRLVAQYGDACNLFASSVDEVRH KIDVLRRHCDTVGRDFGEIRVTIIANNDPRPTPETRDEFVRSMADYAKLGVHTTIVIPTTGSPAAWIDGM APAVPQLAELGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1749 | - | - | 100% (293) | putative monooxygenase |
| M. smegmatis MC2 155 | MSMEG_3620 | - | 4e-46 | 42.92% (233) | hypothetical protein MSMEG_3620 |
| M. smegmatis MC2 155 | MSMEG_6454 | - | 5e-35 | 35.69% (255) | hypothetical protein MSMEG_6454 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 1e-46 | 43.35% (233) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3347 | - | 9e-44 | 40.77% (233) | luciferase family protein |
| M. tuberculosis H37Rv | Rv1855c | - | 2e-46 | 43.35% (233) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 4e-10 | 30.05% (183) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2431c | - | 1e-50 | 47.32% (224) | luciferase-like oxidoreductase |
| M. marinum M | MMAR_2729 | - | 8e-49 | 44.21% (233) | oxidoreductase |
| M. avium 104 | MAV_4735 | - | 5e-81 | 52.53% (297) | hypothetical protein MAV_4735 |
| M. thermoresistible (build 8) | TH_1174 | - | 6e-45 | 45.09% (224) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_3024 | - | 6e-49 | 44.49% (236) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3077 | - | 4e-44 | 39.61% (255) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1749|M.smegmatis_MC2_155 --MDLGFHIPIFDIDGGTTAIAGELARVGESAEAAGASWLSFMDHFFQIE
MAV_4735|M.avium_104 --MELGLHFIDF-LPGDPARLGPTLSEAARAAEQGGATLFTLADHFFQME
Mb1886c|M.bovis_AF2122/97 MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLP
Rv1855c|M.tuberculosis_H37Rv MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLP
MMAR_2729|M.marinum_M MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHFYQLP
MUL_3024|M.ulcerans_Agy99 MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHFYQLP
Mflv_3347|M.gilvum_PYR-GCK MSIRLGLQINNFSYGTGVSDLFPTVVAQAKEADTSGFDSVFLMDHFYQLP
Mvan_3077|M.vanbaalenii_PYR-1 MTIRLGLQINNFSYGTPVPDLFPTVVAQAQEADASGFDSVFVMDHFYQLP
TH_1174|M.thermoresistible__bu VSIRLGLQIPNFSYGTGVADLFPTVIAQAREADEAGYDAVFVMDHFYQLP
MAB_2431c|M.abscessus_ATCC_199 MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLP
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTG------E
. : *: .* .
MSMEG_1749|M.smegmatis_MC2_155 PTGLPAEAHMLEGYTTLGYLAAHTETVPLGLLVTGVTYRHPGLLAKIVTT
MAV_4735|M.avium_104 QLG-PAENPFLEGYTSLGFLAAQTSTIELALLVTGVTYRYPGVLAKTVTT
Mb1886c|M.bovis_AF2122/97 MLG-TPDQPMLEAYTALGALATATERLQLGALVTGNTYRSPTLLAKIITT
Rv1855c|M.tuberculosis_H37Rv MLG-TPDQPMLEAYTALGALATATERLQLGALVTGNTYRSPTLLAKIITT
MMAR_2729|M.marinum_M MLG-TPDQPMLEAYTALGALATATERLQLGTLVTGNTYRNPALLAKIITT
MUL_3024|M.ulcerans_Agy99 MLG-TPDQPMLEAYTALGALATATERLQLGTLVTGNTYRNPALLAKIITT
Mflv_3347|M.gilvum_PYR-GCK GIG-TPDQPMLEAYTALGALAAATDSVQLGTLVTGNTYRNPTLLAKNITT
Mvan_3077|M.vanbaalenii_PYR-1 GLG-TPDQPMLEAYTALGALAAVTQNVQLGTLVTGNTYRNPTLLAKNITT
TH_1174|M.thermoresistible__bu MLG-DPDEPMLEAYTALGGLATSTERVQLGTLVTGNTYRNPTLLAKAVTT
MAB_2431c|M.abscessus_ATCC_199 MIG-TPDQPMLEAYTALGALASATSTIQLSTLVTGNTYRNPALLAKAVTT
MLBr_00348|M.leprae_Br4923 AWG-------SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALT
* :.**.*. .: *. : *. *. : * * * *
MSMEG_1749|M.smegmatis_MC2_155 LDVLSGGRAVLGVGAAWFEREHVGLGVPFPPLAERFERLEETLQICAQMW
MAV_4735|M.avium_104 LDVLSQGRSILGLGAAWYEREHTALGIPYPALSTRFEMLEETLQICLQMW
Mb1886c|M.bovis_AF2122/97 LDVVSAGRAILGIGAGWFELEHRQLGFEFGTFSDRFNRLEEALQILEPMV
Rv1855c|M.tuberculosis_H37Rv LDVVSAGRAILGIGAGWFELEHRQLGFEFGTFSDRFNRLEEALQILEPMV
MMAR_2729|M.marinum_M LDVVSAGRAVLGIGAGWFELEHRQLGYEFGTFTDRFNRLEEALQILDPMI
MUL_3024|M.ulcerans_Agy99 LDVVSAGRAVLGIGAGWFELEHRQLGYEFGTFTDRFNRLEEALQILDPII
Mflv_3347|M.gilvum_PYR-GCK LDVISAGRAILGIGTGWFELEHDQLGYEFGTFTDRFNKLGEALQIILPMI
Mvan_3077|M.vanbaalenii_PYR-1 LDVISQGRAVLGIGTGWFELEHDQLGYEFGTFTERFDKLDEALQIIVPML
TH_1174|M.thermoresistible__bu LDVMSQGRAVLGIGTGWFELEHQQLGYEFGTFTDRFNRLYEALEIIVPMI
MAB_2431c|M.abscessus_ATCC_199 LDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTDRFERLTEALEIIPPML
MLBr_00348|M.leprae_Br4923 LDHLSGGRHILGLGVSGPQVVEGWYGQPFP---KPLSRTREYIDIVRQVW
** :* ** :**:*.. : . * : :. * ::* :
MSMEG_1749|M.smegmatis_MC2_155 DPADNGPYDGKYYQLAETLCSPQ------------PINRPKVMIGGSGER
MAV_4735|M.avium_104 S-DDNGAYQGKHYRLAETICAPQ------------PIRRPPILIGGDGEK
Mb1886c|M.bovis_AF2122/97 K-GERPTFFGDWYTTESAMAEPR------------YRDRIPILIGGGGEK
Rv1855c|M.tuberculosis_H37Rv K-GERPTFFGDWYTTESAMAEPR------------YRDRIPILIGGGGEK
MMAR_2729|M.marinum_M K-GERPTFSGSWYQAESAMAEPR------------YRDRIPILIGGGGEK
MUL_3024|M.ulcerans_Agy99 K-GERPTFSGSWYQAESAMAEPR------------YRDRIPILIGGGGEK
Mflv_3347|M.gilvum_PYR-GCK K-GETPTFSGEYYSVKDAMANPR------------FREHIPLMIGGSGEK
Mvan_3077|M.vanbaalenii_PYR-1 K-GERPTFTGRHYRVQEAMANPR------------FREHIPLMIGGSGEK
TH_1174|M.thermoresistible__bu E-GKRPTFEGRYYRVESAAAEPR------------FRDRIPLMIGGSGEK
MAB_2431c|M.abscessus_ATCC_199 R-GERPTFEGKYYRTESALNEPR------------LRPNIPIMIGGSGEK
MLBr_00348|M.leprae_Br4923 AREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPK
* * : . :::*. * :
MSMEG_1749|M.smegmatis_MC2_155 KTLRLVAQYGDACN--LFASSVDEVRHKIDVLRRHCDTVGRDFGEIRVTI
MAV_4735|M.avium_104 ETLRLVAQYADVWN--SMSNDLAELEHKIEVLHRHCDAVGRDPRDIRKTC
Mb1886c|M.bovis_AF2122/97 KTFAIAARFADHLN--IVAA-VDELPRKMRALAARCDEAGRDRSTLQTSL
Rv1855c|M.tuberculosis_H37Rv KTFAIAARFADHLN--IVAA-VDELPRKMRALAARCDEAGRDRSTLQTSL
MMAR_2729|M.marinum_M KTFRIAAHWADHLN--IVAA-LDELPRKMDAVAARCEEAGRDPSTLETSV
MUL_3024|M.ulcerans_Agy99 KTFRIAAHWADHLN--IVAA-LDELPRKMDAVAARCEEAGRDPSTLETSV
Mflv_3347|M.gilvum_PYR-GCK KTIPLAARHFDHLN--VIAG-FDELARKIDVVTQACEKIDRDPSTLETSM
Mvan_3077|M.vanbaalenii_PYR-1 KTIPLAARHFDHLN--VIAG-FDELARKIEVIEQRCADIDRDPATLETSV
TH_1174|M.thermoresistible__bu KTIPLAARRFDHLN--LIAG-FDELPGKVAAVKRSCEEIGRDPDTLETST
MAB_2431c|M.abscessus_ATCC_199 KTFGLAVKYADHLN--LLSS-LDEIPHKLTVLRQRCEEAGRDPSTLETSA
MLBr_00348|M.leprae_Br4923 -NVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICA
.. :... * .: . :: : *. :.
MSMEG_1749|M.smegmatis_MC2_155 --IANNDPR---------------------------------PTPETRDE
MAV_4735|M.avium_104 GGLATLDP------------------------------------FEDLDE
Mb1886c|M.bovis_AF2122/97 LLTVMIDET---------------------------------LSPDAIPA
Rv1855c|M.tuberculosis_H37Rv LLTVMIDET---------------------------------LSPDAIPA
MMAR_2729|M.marinum_M MLTVVVDEK---------------------------------AKVERLPA
MUL_3024|M.ulcerans_Agy99 MLTVVVDAK---------------------------------AKVERLPA
Mflv_3347|M.gilvum_PYR-GCK LIGALTGDG---------------------------------VSPDMIPE
Mvan_3077|M.vanbaalenii_PYR-1 LVGALVGDD---------------------------------VSPDQIPD
TH_1174|M.thermoresistible__bu LVSVMVDDN---------------------------------ITDDMLPE
MAB_2431c|M.abscessus_ATCC_199 FFSVFIDDDSATAWKLAASQLSQNG-----------------IDLDTLPD
MLBr_00348|M.leprae_Br4923 SAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVD
MSMEG_1749|M.smegmatis_MC2_155 FVR------------------SMADYAKLGVHTTIVIPTTG---SPAAWI
MAV_4735|M.avium_104 YLR------------------TVERLGRLGIEMINVGPLPGN-PDPVGYI
Mb1886c|M.bovis_AF2122/97 EMS----GRVVVGSPAQIADQIQAKVLDAGVDGLIINLAPH--GYLPGVI
Rv1855c|M.tuberculosis_H37Rv EMS----GRVVVGSPAQIADQIQAKVLDAGVDGLIINLAPH--GYLPGVI
MMAR_2729|M.marinum_M ETS----RRMVTGSPAQIADQVQTKVLDTGIDGVIMNLSAH--GHSPGLI
MUL_3024|M.ulcerans_Agy99 ETS----RRMVTGSPAQIADQVQTKVLDTGIDGVIMNLSAH--GHSPGLI
Mflv_3347|M.gilvum_PYR-GCK DFR----QRMVAGTPEQIAEQVQSKVLDAGVDGVILFVPTQTVGYQPGQI
Mvan_3077|M.vanbaalenii_PYR-1 EFK----QRMVAGTVDQVAEQIKTKVLDAGIDGVILYVPTQIVGYQPGQI
TH_1174|M.thermoresistible__bu KAR----GRLLVGSAERIAEQLQTKVLDAGVDGVIVNMATKVQGYRPGLI
MAB_2431c|M.abscessus_ATCC_199 EARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLNAPAT--GHLPGVV
MLBr_00348|M.leprae_Br4923 EVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMM
* . :
MSMEG_1749|M.smegmatis_MC2_155 DGM-APAVPQLAELGS-
MAV_4735|M.avium_104 RRLGDEVIPRLAEIG--
Mb1886c|M.bovis_AF2122/97 TTAAEALRPLLGV----
Rv1855c|M.tuberculosis_H37Rv TTAAEALRPLLGV----
MMAR_2729|M.marinum_M TTVAEALRPLLTG----
MUL_3024|M.ulcerans_Agy99 TTVAEALRPLLTG----
Mflv_3347|M.gilvum_PYR-GCK TALGEALKPLVAG----
Mvan_3077|M.vanbaalenii_PYR-1 TALGEALAPLVTA----
TH_1174|M.thermoresistible__bu TALGEALRPRVGA----
MAB_2431c|M.abscessus_ATCC_199 ELIGNTLRPLFKN----
MLBr_00348|M.leprae_Br4923 MVSASSVEQVRDLAGLF