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MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAAGFDVLAFPDHLVPSVSPFAGATAAAMATQRLH TGTLVLNNDFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGATRVARLIESAHLIRA LLDAEPVDFDGQHYRVHAEAGSLVAPPKVRVPLLVGGNGTEVLRLGGRIADIVGLAGISHNRDATQVRFT HFDADGLADRIAVVRHAAGDRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQVLESPFLLLGTH EQMAEALAARQRRFGVSYWTVFDEWAGRASAMRDIAEVIALLRYG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2893 | - | - | 100% (325) | POSSIBLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv0791c | - | 4e-16 | 34.46% (148) | hypothetical protein Rv0791c |
| M. tuberculosis H37Rv | Rv1855c | - | 3e-15 | 30.15% (199) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2917 | - | 0.0 | 100.00% (325) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1815 | - | 3e-39 | 35.62% (306) | luciferase family protein |
| M. leprae Br4923 | MLBr_00269 | - | 1e-12 | 30.73% (192) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4496c | - | 4e-18 | 35.37% (147) | luciferase-like monooxygenase |
| M. marinum M | MMAR_2775 | - | 1e-36 | 35.71% (308) | oxidoreductase |
| M. avium 104 | MAV_1042 | - | 5e-35 | 32.90% (310) | hypothetical protein MAV_1042 |
| M. smegmatis MC2 155 | MSMEG_2516 | - | 1e-109 | 65.27% (311) | putative oxidoreductase |
| M. thermoresistible (build 8) | TH_4285 | - | 1e-18 | 34.46% (148) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2972 | - | 3e-35 | 37.59% (274) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0757 | - | 1e-123 | 71.06% (311) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2893|M.tuberculosis_H37Rv ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Mb2917|M.bovis_AF2122/97 ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Mvan_0757|M.vanbaalenii_PYR-1 ------------------------MRFGLTTALPRDGAAAREFAQRVEAA
MSMEG_2516|M.smegmatis_MC2_155 ------------------------MRFGLHTALPR-GTDFAEFARGVEDS
MMAR_2775|M.marinum_M MTLRLPRTRWLARLPAGSVTPVPEFRFSFNVFRIDPVHTFIETCRRAEQW
MUL_2972|M.ulcerans_Agy99 ---------------------MPEFRFSFNVFRIDPVHTFIETCRRAEQW
Mflv_1815|M.gilvum_PYR-GCK -----MPLPPAVQTWTYDHDVAKEFRFGVGVTRVSTRAKLEDDARRAEAL
MAV_1042|M.avium_104 --------------------MAKDFRFGMSMRFYKSREALLDKAKRAEDA
MAB_4496c|M.abscessus_ATCC_199 --------------MRFAFKTSPQNTTWDDMLAIWKVADDIEVFESGWTF
TH_4285|M.thermoresistible__bu --------------MQFGFKTSPQNTTWQDMLSVWRAADDIDVFESGWTF
MLBr_00269|M.leprae_Br4923 -------------MAELRLGYKASAEQFAPRELVELGVAAEAHGMDSATV
Rv2893|M.tuberculosis_H37Rv GFDVLAFPDHLVPSVSPFAGATAAAMATQRLHTGTLVLNNDFRH-PVDTA
Mb2917|M.bovis_AF2122/97 GFDVLAFPDHLVPSVSPFAGATAAAMATQRLHTGTLVLNNDFRH-PVDTA
Mvan_0757|M.vanbaalenii_PYR-1 GIDVLTFADHLAPAVAPFSGATAAAAVTSRLHVGTLVLNNDFRH-PVETA
MSMEG_2516|M.smegmatis_MC2_155 GFDVLTVPDHIAPILSPFAGCAAAGAVTSRLHTGTLVLNNDLRH-PVDVA
MMAR_2775|M.marinum_M GYDAVFAADHLG-IAAPFMTLVAAAAATDRMRVGTLVLNAPWWN-PALLA
MUL_2972|M.ulcerans_Agy99 GYDAVFAADHLG-IAAPFMTLVAAAAATDRMRVGILLLNAPWWN-PALLA
Mflv_1815|M.gilvum_PYR-GCK GFDVLHVPDHLG-GSAPFPVMTAVAMATTSLRVGTFVLNSAFYR-PALLA
MAV_1042|M.avium_104 GFDILCVPDHLG-AAAPFPTLTAVAMVTTTLRLSMYVLNSAFYK-PALLS
MAB_4496c|M.abscessus_ATCC_199 DHFYPIFSDPTGPCLEGWVTLTALAQATQRLRVGVLVTGIHYRH-PAVLA
TH_4285|M.thermoresistible__bu DHFYPIFSDPTGPCLEGWTTLTALAQATTRLRVGVLVTGIHYRH-PAVLA
MLBr_00269|M.leprae_Br4923 SDHFQPWRHQGGHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIG
. . .* . * : . : *. .
Rv2893|M.tuberculosis_H37Rv REAAGVATLAEGRFELGLGAGHRRSEYD-AAGITFDSGATRVARLIESAH
Mb2917|M.bovis_AF2122/97 REAAGVATLAEGRFELGLGAGHRRSEYD-AAGITFDSGATRVARLIESAH
Mvan_0757|M.vanbaalenii_PYR-1 REAAGVATVSDGRFELGIGAGHMKSEYD-SAGIPFDGGGTRVSRLVESVT
MSMEG_2516|M.smegmatis_MC2_155 RESGTLAAMSGGRFELGLGAGHMKSEYD-AVGVKFDRGGVRVDRLVEAVS
MMAR_2775|M.marinum_M RDIATTDVLTGGRLEVGLGAGHMKWEYD-QADIPFPSFTTRTARLRQTIE
MUL_2972|M.ulcerans_Agy99 RDIATTDVLTGGRLEVGLGAGHMKWEYD-QADIPFPSFTTRTARLRQTIE
Mflv_1815|M.gilvum_PYR-GCK RDVAALNDLSDGRVELGLGTGYVREEFD-AAGIPYPTAGERVDHLKLTAA
MAV_1042|M.avium_104 RDMQALDLLSDGRLEIGLGTGYVREEFE-AAEIPYPSARERVDYLEHMTK
MAB_4496c|M.abscessus_ATCC_199 NMASALDIVSGGRLELGIGAGWNEEESG-AYGIELGSIKERFDRFEEACE
TH_4285|M.thermoresistible__bu NMASALDIISAGRLELGIGAGWNEEESG-AYGIELGTLKERFDRFEEACQ
MLBr_00269|M.leprae_Br4923 QAFATMGCLYPNRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVR
. : .*. :*:*:* * * :
Rv2893|M.tuberculosis_H37Rv LIRALLDAEPVDFDGQHYRVHAEAG----SLVAPPKVRVPLLVGGNGT-E
Mb2917|M.bovis_AF2122/97 LIRALLDAEPVDFDGQHYRVHAEAG----SLVAPPKVRVPLLVGGNGT-E
Mvan_0757|M.vanbaalenii_PYR-1 VLRALLHGDAVDFDGDHYRVHAAAG----EIVAAPVHRVPILIGGNGT-R
MSMEG_2516|M.smegmatis_MC2_155 VIAPLLAGEAVDVDGSHYCVRGAAG----ELVAPPGVPVPLLIGGNGT-R
MMAR_2775|M.marinum_M ELASRFAEEGFAQQAELREAHNIAVLRPTQRRGFGGYGPPLLVGGTGD-Q
MUL_2972|M.ulcerans_Agy99 ELASRFAEDGFAQQAELREAHNIAVLRPTQRRGFGGYGPPLLVGGTGD-Q
Mflv_1815|M.gilvum_PYR-GCK HIAEHLPDV------------------------------PIMIAGNGD-R
MAV_1042|M.avium_104 YLKEHHPST------------------------------PLIIAGNGD-R
MAB_4496c|M.abscessus_ATCC_199 VLTGLLSRETTNFDGKFYQLKDARN----EPKGPQKPHPPICIGGSGEKR
TH_4285|M.thermoresistible__bu VLISLLSQETTDFDGAYYRLKSARN----EPKGPQQPHPPICIGGSGEKR
MLBr_00269|M.leprae_Br4923 LMRELWRGDRVDFDGDYYQLKGASIY------DVPEGGVPIYIAAGGP-E
: *: :.. * .
Rv2893|M.tuberculosis_H37Rv VLRLGGRIADIVGLAGISHNRDATQVRF------------THFDADGLAD
Mb2917|M.bovis_AF2122/97 VLRLGGRIADIVGLAGISHNRDATQVRF------------THFDADGLAD
Mvan_0757|M.vanbaalenii_PYR-1 VLQLAGRIADIVGFAGISHNRDATRVRL------------SHFDGAGLAD
MSMEG_2516|M.smegmatis_MC2_155 VLQLAGRVADIAGLAGFSHNHDATEIRL------------THFGPAGLLD
MMAR_2775|M.marinum_M VLRLAAQYADTVSIACLYQVKGRPPGTM------------RLATVAEIEQ
MUL_2972|M.ulcerans_Agy99 VLRLAAQYADTVSIACLYQVKGRPPGTM------------RLAIVAEIEQ
Mflv_1815|M.gilvum_PYR-GCK VLRTAARFADIVGFTGGDRAATG--------------------DEDPLGD
MAV_1042|M.avium_104 VLTIAARNADIIGLTG--AKVRD--------------------VEDPFAE
MAB_4496c|M.abscessus_ATCC_199 TLRITARYAQHWNFVGGPPEEFARK-----------------------RE
TH_4285|M.thermoresistible__bu TLRITAKYADHWNFVGGPPEEFARK-----------------------RD
MLBr_00269|M.leprae_Br4923 VAKYAGRAGEGFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIE
. .: .: . :
Rv2893|M.tuberculosis_H37Rv RIAVVRHAAGDRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQV
Mb2917|M.bovis_AF2122/97 RIAVVRHAAGDRFEAIELNALIQAVVCTNDRNAAAAELAATLGGITPEQV
Mvan_0757|M.vanbaalenii_PYR-1 RIGVVREAAGERFAQIELNALIQAVVVTTDRQRAAAELAAAFG-ADPETL
MSMEG_2516|M.smegmatis_MC2_155 RIGVVRDAAGARFEQIELNALIQFVAHTEDPAAAAAELAGTLG-TEPSVL
MMAR_2775|M.marinum_M RVAYVRRCAGAARHPELHTLIQEVVLTDDRRKVAGMLAAKYGNLLTANEI
MUL_2972|M.ulcerans_Agy99 RVAYVRRCAGAARHPELHTLIQEVVLTDDRREVAGMLAAKYGNLLTANEI
Mflv_1815|M.gilvum_PYR-GCK RIGFVRAAAGERFAALELNIAITAIPLDSSGQPDLTIPRISLPGLSDDEL
MAV_1042|M.avium_104 RVEFVRNAAGDRFDSLELNLAITAMPRVGETEPDLKLTRSYSPELTDEQI
MAB_4496c|M.abscessus_ATCC_199 VLAAHCADIGRDPKEITLSAHIRLGADRDYARVVDEAASLGAEGLDLAII
TH_4285|M.thermoresistible__bu VLAAHCADVGRDPREIRLSAHVRLGEDGDCRKVVDEAAALASEGLDLAIV
MLBr_00269|M.leprae_Br4923 IKMSYDPDPEQALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQV
:
Rv2893|M.tuberculosis_H37Rv LESPFLLLGTHEQMAEALAARQRRFGVSYWTVFDEWAGRASAMRDIAEVI
Mb2917|M.bovis_AF2122/97 LESPFLLLGTHEQMAEALAARQRRFGVSYWTVFDEWAGRASAMRDIAEVI
Mvan_0757|M.vanbaalenii_PYR-1 LCSPFVLLGTHEQMAEQLLARRREFGIGYWTVFDELPGRESALPDISEVI
MSMEG_2516|M.smegmatis_MC2_155 LESPFVLIGTYEQMAEALAERQRLYGVSYWTVIDAWAGRESAMPHLAEVI
MMAR_2775|M.marinum_M LQSPTLLIGTVEQIARQLRANRERYGFTHYTIPQPH------VAAFAPVI
MUL_2972|M.ulcerans_Agy99 LQSPTLLIGTVEQIARQLRANRERYGFTHYTIPQPH------VAAFAPVI
Mflv_1815|M.gilvum_PYR-GCK LRHPSVLSGSTTEIADRIHGYRDVYGISYVIVQMRH------AEAFGAVI
MAV_1042|M.avium_104 LSMPSVLSGSPRDIADTLSAYRDKYGVSSFTVQDNH------IDNFAKVI
MAB_4496c|M.abscessus_ATCC_199 YLPPPYDPAVLEPLAQALRG------------------------------
TH_4285|M.thermoresistible__bu YLPTPHTPAVLEPLAEAIRDSGLPAR------------------------
MLBr_00269|M.leprae_Br4923 AKRWIVVSDPDEAVAR--VGQYVTWGLNHLVFHAPGHNQRRFLELFEKDL
:*
Rv2893|M.tuberculosis_H37Rv ALLRYG--
Mb2917|M.bovis_AF2122/97 ALLRYG--
Mvan_0757|M.vanbaalenii_PYR-1 ALLR----
MSMEG_2516|M.smegmatis_MC2_155 KLLR----
MMAR_2775|M.marinum_M TVLGDLN-
MUL_2972|M.ulcerans_Agy99 TVLGDLN-
Mflv_1815|M.gilvum_PYR-GCK DLLR----
MAV_1042|M.avium_104 AELR----
MAB_4496c|M.abscessus_ATCC_199 --------
TH_4285|M.thermoresistible__bu --------
MLBr_00269|M.leprae_Br4923 APRLRRLG