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MSIPNDHLVDVAIRQEHRAQHRFRTLLGAGVGNTLEWYDWSVYAIFAPFFAHQFFVGDGGTGAMLSTLAV FAVGFLMRPVGGFLFGWLADRRGRRFSMTTSMLLMAAGSLVIGVAPVQADVGIWAAVILIVARLAQGLAH GGEIAASYTYIAEVAPPARRGLWSTSLYVSVTAGIVLASVIGAAASSILGADALAQWAWRLPFLLGGLLG VVGLYLRRSLPETEAFLAEDTGPAQQPATTRDVIRGLRSHKASLARMVGFSLASTVVVYTWAIGISGFAI STRGVPAGAALWATVAANLVFMATLPLWGKLSDRYGRRPVFITYSIAFMVLSFPLLAAIDDSPVRLFLIV SVALFFLGAFVGIMPAYFAELFPTHVRASGIGVPYSFTVAVFGGTAPYIATWLASHHLEWIFALYSVVLA AIGLVTTLLSPETRGRNLL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2952 | - | - | 100% (439) | transport gene |
| M. smegmatis MC2 155 | MSMEG_3990 | - | e-108 | 44.79% (413) | putative transporter |
| M. smegmatis MC2 155 | MSMEG_1152 | - | 2e-68 | 36.89% (412) | citrate-proton symporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3503c | kgtP | 1e-62 | 34.07% (408) | dicarboxylic acid transport integral membrane protein KgtP |
| M. gilvum PYR-GCK | Mflv_2381 | - | 2e-70 | 36.71% (414) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3476c | kgtP | 9e-62 | 33.82% (408) | dicarboxylic acid transport integral membrane protein KgtP |
| M. leprae Br4923 | MLBr_01562 | - | 1e-09 | 29.83% (181) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_3808c | - | 3e-63 | 33.72% (430) | dicarboxylic acid transport integral membrane protein KgtP |
| M. marinum M | MMAR_4238 | - | 3e-42 | 29.58% (426) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 4e-55 | 31.41% (433) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_3722 | - | 4e-64 | 34.21% (418) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 7e-43 | 29.81% (426) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_4266 | - | 7e-68 | 35.17% (418) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3503c|M.bovis_AF2122/97 ----------------------MTVSIAPPSRPS-QAETR----RAIWNT
Rv3476c|M.tuberculosis_H37Rv ----------------------MTVSIAPPSRPS-QAETR----RAIWNT
MAB_3808c|M.abscessus_ATCC_199 ----------------------MAVSAADTSTPSGRAQTR----RAIWNT
MSMEG_2952|M.smegmatis_MC2_155 ----------------------MSIPNDHLVDVAIRQEHRA---QHRFRT
Mflv_2381|M.gilvum_PYR-GCK ----------------------MTVDEDQR-RPSGAEPAA------VRQA
Mvan_4266|M.vanbaalenii_PYR-1 ----------------------MTVKET---RP--AAPGA------VSRA
TH_3722|M.thermoresistible__bu ----------------------VSENPSIVSAPPAPDAVV------IRKA
MMAR_4238|M.marinum_M ----------------------------------------------MSRV
MUL_0949|M.ulcerans_Agy99 ----------------------------------------------MSRV
MAV_4627|M.avium_104 --------------MAATLPAPAPAGLADGHPLDESAEQQR---RRLRIV
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb3503c|M.bovis_AF2122/97 IRGS-SGNLVEWYDVYVYT-VFATYFEDQFFD-RADRNSTVYVYAIFAVT
Rv3476c|M.tuberculosis_H37Rv IRGS-SGNLVEWYDVYVYT-VFATYFEDQFFD-RADRNSTVYVYAIFAVT
MAB_3808c|M.abscessus_ATCC_199 IRGS-SGNLVEWYDVYVYT-VFAMYFEKQFFD-DSDQNSTVYVYAIFAVT
MSMEG_2952|M.smegmatis_MC2_155 LLGAGVGNTLEWYDWSVYA-IFAPFFAHQFFVGDGGTGAMLSTLAVFAVG
Mflv_2381|M.gilvum_PYR-GCK VRGAAIGNTVEWFDFAIYG-FLATYIADKFFPSGDETAALLSTFAVFAAA
Mvan_4266|M.vanbaalenii_PYR-1 VRGAAIGNAVEWFDFAIYG-FLATYIAEKFFPPGDETAALLNTFAIFAAA
TH_3722|M.thermoresistible__bu VTGASIGNAVEWFDFAIYG-FLATYIAANFFPAGDDTAALLNTFAIFAAA
MMAR_4238|M.marinum_M ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MUL_0949|M.ulcerans_Agy99 ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MAV_4627|M.avium_104 VAASLLGTTVEWYDFFLYATAAGLVFNKVFFPNESSLVGTLLAFATFAVG
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
. . : . : . : . .
Mb3503c|M.bovis_AF2122/97 FVTRPVGSWFFG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRS----
Rv3476c|M.tuberculosis_H37Rv FVTRPVGSWFLG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRS----
MAB_3808c|M.abscessus_ATCC_199 FITRPLGSWFFG-RFADRNGRRAALTLSVSLMAACSMVIALVPSRG----
MSMEG_2952|M.smegmatis_MC2_155 FLMRPVGGFLFG-WLADRRGRRFSMTTSMLLMAAGSLVIGVAPVQA----
Mflv_2381|M.gilvum_PYR-GCK FFMRPLGGFFFG-PLGDRIGRQRVLAIVILLMSASTLAIGLVPSYD----
Mvan_4266|M.vanbaalenii_PYR-1 FFMRPLGGFFFG-PLGDRIGRQRVLALVILLMSASTLAIGLVPGYD----
TH_3722|M.thermoresistible__bu FVVRPLGGFFFG-PLGDRIGRQRVLALVILLMSGATLTMGLLPTYE----
MMAR_4238|M.marinum_M FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTA----
MUL_0949|M.ulcerans_Agy99 FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTA----
MAV_4627|M.avium_104 FVMRPIGGLVFG-HIGDRIGRKRSLALTMLIMGGATALIGVLPTAA----
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
:. * .:* :.* **: : : :: : .:
Mb3503c|M.bovis_AF2122/97 -----SIGVAAPILLILCRLVQGFATG-GEYGTSVTYMSEAATRERRGYF
Rv3476c|M.tuberculosis_H37Rv -----SIGVAAPILLILCRLVQGFATG-GEYGTSATYMSEAATRERRGYF
MAB_3808c|M.abscessus_ATCC_199 -----SIGMAAPIVLILCRLVQGFATG-GEYGTSATYMSEAATRERRGFF
MSMEG_2952|M.smegmatis_MC2_155 -----DVGIWAAVILIVARLAQGLAHG-GEIAASYTYIAEVAPPARRGLW
Mflv_2381|M.gilvum_PYR-GCK -----SIGVLAPILLLVLRCLQGFSAG-GEYGSGACFLAEYAPNRHRGFV
Mvan_4266|M.vanbaalenii_PYR-1 -----SIGVLAPILLLLLRCLQGFSAG-GEYGSGACFLAEYAPDRHRGFV
TH_3722|M.thermoresistible__bu -----SIGVLAPLLLLLLRCLQGFSAG-GEYGGGAVYLAEFAPDRRRGLI
MMAR_4238|M.marinum_M -----TIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MUL_0949|M.ulcerans_Agy99 -----TIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MAV_4627|M.avium_104 -----QIGAWAPVLLLVLRVLQGFALG-GEWGGAVLLAVEHSPGDRRGRY
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
:* . :: * .. : *
Mb3503c|M.bovis_AF2122/97 SSFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGAAI
Rv3476c|M.tuberculosis_H37Rv SSFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGAAI
MAB_3808c|M.abscessus_ATCC_199 SSFQYVTLVGGHVLAQFTLLIILTVFD--TAQVHEFGWRIAFATGGVAAI
MSMEG_2952|M.smegmatis_MC2_155 STSLYVSVTAGIVLASVIGAAASSILG--ADALAQWAWRLPFLLGGLLGV
Mflv_2381|M.gilvum_PYR-GCK VSFLVWSVVVGFLAGAITVTALETWLS--EDAMNSYGWRIPFMIAGLLGA
Mvan_4266|M.vanbaalenii_PYR-1 VSFLVWSVVVGFLLGSVTVTALEATLS--ESAMNSFGWRIPFLIAGALGA
TH_3722|M.thermoresistible__bu VTFMAWSGVLGFLLGSVTVTALQVALP--DQVMTDVGWRIPFLLAGPLGL
MMAR_4238|M.marinum_M GMFTVLGGGVALVVSGLTFLGVNYTIGESSSAFLQWGWRVPFLLSALLIA
MUL_0949|M.ulcerans_Agy99 GMFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWRVPFLLSALLIA
MAV_4627|M.avium_104 GAVPQVGLALGLALGTGIFAFLQIVLG--PARFLSYGWRIGFLLSVLLVA
MLBr_01562|M.leprae_Br4923 VGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILA
*: : .
Mb3503c|M.bovis_AF2122/97 VVFWLRRTMDESLSQE----RLTAIKAGRDHDSGSLRELAT---------
Rv3476c|M.tuberculosis_H37Rv VVFWLRRTMDESLSQE----RLTAIKAGRDHDSGSLRELAT---------
MAB_3808c|M.abscessus_ATCC_199 VVYWLRRTMDESLSEE----QLAAIKAGADTSSGSMRELLT---------
MSMEG_2952|M.smegmatis_MC2_155 VGLYLRRSLPETEAFL----AEDTGPAQQPATTRDVIRGLR---------
Mflv_2381|M.gilvum_PYR-GCK VGLYIRLKLGDTP-------EFRSLRESGEVSQSPLREAVT---------
Mvan_4266|M.vanbaalenii_PYR-1 VGLYIRLRLGDTP-------EFEALRESGEVSTTPLKEAVT---------
TH_3722|M.thermoresistible__bu IGLYIRLRLDDTP-------AFTALSEQEEVAQSPLREAVQ---------
MMAR_4238|M.marinum_M FALYVRLEINETPVFAR-AMAQADDQESTAAARAPLAAVLC---------
MUL_0949|M.ulcerans_Agy99 FALYVRLEINETPVFAR-AMAQADDQESTAAARAPLAAVLC---------
MAV_4627|M.avium_104 IGIVVRLRVEETPAFR-------ELQDLQAASTVPIRDILRE--------
MLBr_01562|M.leprae_Br4923 TLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVV
. : :
Mb3503c|M.bovis_AF2122/97 ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
Rv3476c|M.tuberculosis_H37Rv ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
MAB_3808c|M.abscessus_ATCC_199 ----RYRKPLLLCFLITMGGTLAFYTYSVNAPAIVKAAYKDQAMTATWIN
MSMEG_2952|M.smegmatis_MC2_155 ----SHKASLARMVGFSLASTVVVYTWAIGISGFAISTRGVPAGAALWAT
Mflv_2381|M.gilvum_PYR-GCK ----TSWRPILQIIGLVVIHNVGFYIVYTFLPSYFTETLDFSKVDAFWSI
Mvan_4266|M.vanbaalenii_PYR-1 ----TSWRPILQIIGLVVVHNVGFYVVYTFLPSYFTRTLEFSKIDAFYSI
TH_3722|M.thermoresistible__bu ----TAWRSILQVIGLMIIFNVAYYVVFAYMPTYLIKELGLSSSDAFISS
MMAR_4238|M.marinum_M ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MUL_0949|M.ulcerans_Agy99 ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MAV_4627|M.avium_104 ---RRSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGLNRVSVLIAV
MLBr_01562|M.leprae_Br4923 PFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGF
.
Mb3503c|M.bovis_AF2122/97 LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
Rv3476c|M.tuberculosis_H37Rv LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
MAB_3808c|M.abscessus_ATCC_199 LAGLIFLMLLQPVGGIISDKVGRKPLLLFFGFGGVVYTYVLITYLPQVHA
MSMEG_2952|M.smegmatis_MC2_155 VAANLVFMATLPLWGKLSDRYGRRPVFITYSIAFMVLSFPLLAAIDDS--
Mflv_2381|M.gilvum_PYR-GCK TVASLVGIVLIPPLGALSDRIGRKSLLIAGAVAFAVFAYPLFLLLNTG-S
Mvan_4266|M.vanbaalenii_PYR-1 TVASLVGIVLIPPLGALSDRVGRKPLLLAGSIGFAVFAYPLFLLLNTG-S
TH_3722|M.thermoresistible__bu TIACVVALVLILPLAALSDRIGRKPLLVGGAIAFAVLAYPLFLLLNSG-S
MMAR_4238|M.marinum_M VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MUL_0949|M.ulcerans_Agy99 VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MAV_4627|M.avium_104 TIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAFALFGTKKL
MLBr_01562|M.leprae_Br4923 IPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGVP
: . : .: . : : : . :
Mb3503c|M.bovis_AF2122/97 PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
Rv3476c|M.tuberculosis_H37Rv PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
MAB_3808c|M.abscessus_ATCC_199 PIVSFLLVAVSYVLLTGYTSINALVKSELFPSHVRALGVGVGYALANSVF
MSMEG_2952|M.smegmatis_MC2_155 PVRLFLIVSVALFFLGAFVGIMPAYFAELFPTHVRASGIGVPYSFTVAVF
Mflv_2381|M.gilvum_PYR-GCK LAAAIAAHAALAAIESVFVSASLAAGAELFATKVRSSGYSIGYNVSVAVF
Mvan_4266|M.vanbaalenii_PYR-1 LAAAIAAHAALAAIEAVFVCASLAAGAELFATRVRSSGYSIGYNVSVAIF
TH_3722|M.thermoresistible__bu TAAAMIAHAGLAAIESVVISVAVVTAVEQFTTRVRYSGMSVGYNVCVALF
MMAR_4238|M.marinum_M VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MUL_0949|M.ulcerans_Agy99 VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MAV_4627|M.avium_104 LWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLSFVYQFSGVYA
MLBr_01562|M.leprae_Br4923 YFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQSLG
. . * . .
Mb3503c|M.bovis_AF2122/97 GGTAPLIYQALKER------------------------DQVPMFIAYVTA
Rv3476c|M.tuberculosis_H37Rv GGTAPLIYQALKER------------------------DQVPMFIAYVTA
MAB_3808c|M.abscessus_ATCC_199 GGTAPLIYQALKEH------------------------DQVPLFIGYVTV
MSMEG_2952|M.smegmatis_MC2_155 GGTAPYIATWLASH------------------------HLEWIFALYSVV
Mflv_2381|M.gilvum_PYR-GCK GGTAPYVATWLVSR------------------------TGNDIAPAYYLI
Mvan_4266|M.vanbaalenii_PYR-1 GGTAPYVATWLVSR------------------------TGNDIAPAFYVI
TH_3722|M.thermoresistible__bu GGTTPYVMTWLIDT------------------------TANPLAPACAVT
MMAR_4238|M.marinum_M GAAPPLIAGTLLAS------------------------YGSSAVGLMMTA
MUL_0949|M.ulcerans_Agy99 GAAPPLIAGTLLAS------------------------YGSSAVGLMMTA
MAV_4627|M.avium_104 SGVTPMILTALIAA------------------------LGG-APWLACGY
MLBr_01562|M.leprae_Br4923 GPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLLWVAG
. : :
Mb3503c|M.bovis_AF2122/97 CIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-
Rv3476c|M.tuberculosis_H37Rv CIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-
MAB_3808c|M.abscessus_ATCC_199 CIAISLVVYLFFLKNKSQTYLDREQGSAFNR---
MSMEG_2952|M.smegmatis_MC2_155 LAAIGLVTTLLSPETRGRNLL-------------
Mflv_2381|M.gilvum_PYR-GCK AAAIVSLLTVLTMRETARKPLRKLVHP-------
Mvan_4266|M.vanbaalenii_PYR-1 AAAVVTFLTVLTMRETARQPLRKLVSD-------
TH_3722|M.thermoresistible__bu LAAVVSLGVVMTLRETAARPLAGTP---------
MMAR_4238|M.marinum_M LVAASLLCTYLLPETAGAPLTAA-----------
MUL_0949|M.ulcerans_Agy99 LVAASLLCTYLLPETAGAPLTAA-----------
MAV_4627|M.avium_104 LVATAVISVLATALIRDRDLYL------------
MLBr_01562|M.leprae_Br4923 AVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL
. .