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AVSAADTSTPSGRAQTRRAIWNTIRGSSGNLVEWYDVYVYTVFAMYFEKQFFDDSDQNSTVYVYAIFAVT FITRPLGSWFFGRFADRNGRRAALTLSVSLMAACSMVIALVPSRGSIGMAAPIVLILCRLVQGFATGGEY GTSATYMSEAATRERRGFFSSFQYVTLVGGHVLAQFTLLIILTVFDTAQVHEFGWRIAFATGGVAAIVVY WLRRTMDESLSEEQLAAIKAGADTSSGSMRELLTRYRKPLLLCFLITMGGTLAFYTYSVNAPAIVKAAYK DQAMTATWINLAGLIFLMLLQPVGGIISDKVGRKPLLLFFGFGGVVYTYVLITYLPQVHAPIVSFLLVAV SYVLLTGYTSINALVKSELFPSHVRALGVGVGYALANSVFGGTAPLIYQALKEHDQVPLFIGYVTVCIAI SLVVYLFFLKNKSQTYLDREQGSAFNR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3808c | - | - | 100% (448) | dicarboxylic acid transport integral membrane protein KgtP |
| M. abscessus ATCC 19977 | MAB_2263c | - | 5e-57 | 32.33% (433) | major facilitator transporter |
| M. abscessus ATCC 19977 | MAB_4485 | - | 4e-37 | 25.86% (437) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3503c | kgtP | 0.0 | 81.39% (446) | dicarboxylic acid transport integral membrane protein KgtP |
| M. gilvum PYR-GCK | Mflv_2381 | - | 3e-55 | 31.26% (435) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3476c | kgtP | 0.0 | 81.39% (446) | dicarboxylic acid transport integral membrane protein KgtP |
| M. leprae Br4923 | MLBr_01562 | - | 2e-05 | 21.58% (329) | putative transmembrane efflux protein |
| M. marinum M | MMAR_4238 | - | 7e-32 | 26.42% (386) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 3e-35 | 27.39% (398) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_0985 | - | 0.0 | 84.88% (443) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_3400 | - | 7e-52 | 30.62% (369) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 3e-32 | 26.42% (386) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_4266 | - | 8e-57 | 32.94% (425) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3808c|M.abscessus_ATCC_199 ---------MAVS-AADTSTPSGR---------AQTRRAIWNTIRGS---
MSMEG_0985|M.smegmatis_MC2_155 ---------MTVAGQAHPPTRSGA---------AETRRAIWNTIRGS---
Mb3503c|M.bovis_AF2122/97 ---------MTVS--IAPPSRPSQ---------AETRRAIWNTIRGS---
Rv3476c|M.tuberculosis_H37Rv ---------MTVS--IAPPSRPSQ---------AETRRAIWNTIRGS---
MMAR_4238|M.marinum_M --------------------------------------MSRVALACV---
MUL_0949|M.ulcerans_Agy99 --------------------------------------MSRVALACV---
MAV_4627|M.avium_104 ---------MAATLPAPAPAGLADGHPLDESAEQQRRRLRIVVAASL---
Mflv_2381|M.gilvum_PYR-GCK ---------MTVDEDQRRPS------------GAEPAAVRQAVRGAA---
Mvan_4266|M.vanbaalenii_PYR-1 ---------MTVKET--RP--------------AAPGAVSRAVRGAA---
TH_3400|M.thermoresistible__bu ---------LTTERTDPPQDPSVE-------QEQPPGVLRKAIAASA---
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
MAB_3808c|M.abscessus_ATCC_199 -----SGNLVEWYDVYVYTVFAMYFEKQFFDD--SDQNSTVYVYAIFAVT
MSMEG_0985|M.smegmatis_MC2_155 -----SGNLVEWYDVYVYTVFATYFEKQFFAE--GDENSTVYVYAIFAVT
Mb3503c|M.bovis_AF2122/97 -----SGNLVEWYDVYVYTVFATYFEDQFFDR--ADRNSTVYVYAIFAVT
Rv3476c|M.tuberculosis_H37Rv -----SGNLVEWYDVYVYTVFATYFEDQFFDR--ADRNSTVYVYAIFAVT
MMAR_4238|M.marinum_M -----VGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MUL_0949|M.ulcerans_Agy99 -----VGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MAV_4627|M.avium_104 -----LGTTVEWYDFFLYATAAGLVFNKVFFPNESSLVGTLLAFATFAVG
Mflv_2381|M.gilvum_PYR-GCK -----IGNTVEWFDFAIYGFLATYIA-DKFFPSGDETAALLSTFAVFAAA
Mvan_4266|M.vanbaalenii_PYR-1 -----IGNAVEWFDFAIYGFLATYIA-EKFFPPGDETAALLNTFAIFAAA
TH_3400|M.thermoresistible__bu -----VGNATEWFDYGLYAYGVTYIS-VAIFP-GDGATATLLALMTFAVS
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
. . : . : .
MAB_3808c|M.abscessus_ATCC_199 FITRPLGSWFFG-RFADRNGRRAALTLSVSLMAACSMVIALVPSRG----
MSMEG_0985|M.smegmatis_MC2_155 FLTRPIGSWFFG-RFADRRGRRAALTFSVSLMALCSLVIAIVPSRE----
Mb3503c|M.bovis_AF2122/97 FVTRPVGSWFFG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRS----
Rv3476c|M.tuberculosis_H37Rv FVTRPVGSWFLG-RFADRRGRRAALTFSVSLMAACSLIVALVPSRS----
MMAR_4238|M.marinum_M FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTA----
MUL_0949|M.ulcerans_Agy99 FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALSTVTVGVVPSTA----
MAV_4627|M.avium_104 FVMRPIGGLVFG-HIGDRIGRKRSLALTMLIMGGATALIGVLPTAA----
Mflv_2381|M.gilvum_PYR-GCK FFMRPLGGFFFG-PLGDRIGRQRVLAIVILLMSASTLAIGLVPSYD----
Mvan_4266|M.vanbaalenii_PYR-1 FFMRPLGGFFFG-PLGDRIGRQRVLALVILLMSASTLAIGLVPGYD----
TH_3400|M.thermoresistible__bu FLVRPLGGFVWG-PLGDRLGRRQVLAITILLMAGATFCVGLVPSYD----
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
:. * . * :.* **: : : :: .: .:
MAB_3808c|M.abscessus_ATCC_199 -----SIGMAAPIVLILCRLVQGFATG-GEYGTSATYMSEAATRERRGFF
MSMEG_0985|M.smegmatis_MC2_155 -----VIGAAAPVILILCRLVQGFATG-GEYGTSATYMSEAATRERRGFF
Mb3503c|M.bovis_AF2122/97 -----SIGVAAPILLILCRLVQGFATG-GEYGTSVTYMSEAATRERRGYF
Rv3476c|M.tuberculosis_H37Rv -----SIGVAAPILLILCRLVQGFATG-GEYGTSATYMSEAATRERRGYF
MMAR_4238|M.marinum_M -----TIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MUL_0949|M.ulcerans_Agy99 -----TIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MAV_4627|M.avium_104 -----QIGAWAPVLLLVLRVLQGFALG-GEWGGAVLLAVEHSPGDRRGRY
Mflv_2381|M.gilvum_PYR-GCK -----SIGVLAPILLLVLRCLQGFSAG-GEYGSGACFLAEYAPNRHRGFV
Mvan_4266|M.vanbaalenii_PYR-1 -----SIGVLAPILLLLLRCLQGFSAG-GEYGSGACFLAEYAPDRHRGFV
TH_3400|M.thermoresistible__bu -----SIGLWAPVLMVILRMIQGFSTG-GEYGGAATFMAEYAPSRRRGLL
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
** . *: * .. . : *
MAB_3808c|M.abscessus_ATCC_199 S--SFQYVTLVGGHVLAQFTLLIILTVFD--TAQVHEFGWRIAFATGGVA
MSMEG_0985|M.smegmatis_MC2_155 S--SFQYVTLVGGHVLAQFTLLIILTAFT--TEQVHDFGWRIGFAIGGVA
Mb3503c|M.bovis_AF2122/97 S--SFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGA
Rv3476c|M.tuberculosis_H37Rv S--SFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGA
MMAR_4238|M.marinum_M G--MFTVLGGGVALVVSGLTFLGVNYTIGESSSAFLQWGWRVPFLLSALL
MUL_0949|M.ulcerans_Agy99 G--MFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWRVPFLLSALL
MAV_4627|M.avium_104 G--AVPQVGLALGLALGTGIFAFLQIVLG--PARFLSYGWRIGFLLSVLL
Mflv_2381|M.gilvum_PYR-GCK V--SFLVWSVVVGFLAGAITVTALETWLS--EDAMNSYGWRIPFMIAGLL
Mvan_4266|M.vanbaalenii_PYR-1 V--SFLVWSVVVGFLLGSVTVTALEATLS--ESAMNSFGWRIPFLIAGAL
TH_3400|M.thermoresistible__bu G--SFLEFGTLAGFSLGALMMLGVSLMLS--DDQMNTWGWRVPFLIAAPL
MLBr_01562|M.leprae_Br4923 VGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILA
. . : :: .
MAB_3808c|M.abscessus_ATCC_199 AIVVYWLRRTMDESLSEEQLAAIKAGADTSS---GSMRELLT--------
MSMEG_0985|M.smegmatis_MC2_155 AIVVFWLRRTMDESLSEEQLEAIKTGKDTSS---GSLGELLT--------
Mb3503c|M.bovis_AF2122/97 AIVVFWLRRTMDESLSQERLTAIKAGRDHDS---GSLRELAT--------
Rv3476c|M.tuberculosis_H37Rv AIVVFWLRRTMDESLSQERLTAIKAGRDHDS---GSLRELAT--------
MMAR_4238|M.marinum_M IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MUL_0949|M.ulcerans_Agy99 IAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC--------
MAV_4627|M.avium_104 VAIGIVVRLRVEETPAFR------ELQDLQAASTVPIRDILRE-------
Mflv_2381|M.gilvum_PYR-GCK GAVGLYIRLKLGDTPEFRSLR---ESGEVSQ---SPLREAVT--------
Mvan_4266|M.vanbaalenii_PYR-1 GAVGLYIRLRLGDTPEFEALR---ESGEVST---TPLKEAVT--------
TH_3400|M.thermoresistible__bu GLIGLYLRSRLDDTPIFRELQ---ESDREEKSIWTEFKDLLV--------
MLBr_01562|M.leprae_Br4923 TLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVV
.
MAB_3808c|M.abscessus_ATCC_199 ----RYRKPLLLCFLITMGGTLAFYTYSVNAPAIVKAAYKDQAMTATWIN
MSMEG_0985|M.smegmatis_MC2_155 ----RYPKALLMCFLITLGGTIAFYTYSVNAPAIVKTTYKDQAMTATWIN
Mb3503c|M.bovis_AF2122/97 ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
Rv3476c|M.tuberculosis_H37Rv ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
MMAR_4238|M.marinum_M ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MUL_0949|M.ulcerans_Agy99 ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MAV_4627|M.avium_104 ---RRSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGLNRVSVLIAV
Mflv_2381|M.gilvum_PYR-GCK ----TSWRPILQIIGLVVIHNVGFYIVYTFLPSYFTETLDFSKVDAFWSI
Mvan_4266|M.vanbaalenii_PYR-1 ----TSWRPILQIIGLVVVHNVGFYVVYTFLPSYFTRTLEFSKIDAFYSI
TH_3400|M.thermoresistible__bu ----EYRGQILRLGGLVVALNVVNYTLLSYMPTYLQTSIGLSTDTALVVP
MLBr_01562|M.leprae_Br4923 PFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGF
: . .
MAB_3808c|M.abscessus_ATCC_199 LAGLIFLMLLQPVGGIISDKVGRKPLLLFFGFGGVVYTYVLITYLPQVHA
MSMEG_0985|M.smegmatis_MC2_155 LFGLIFLMLLQPVGGLISDKVGRKPLLLWFGFGGVIYTYILITYLPQTHS
Mb3503c|M.bovis_AF2122/97 LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
Rv3476c|M.tuberculosis_H37Rv LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
MMAR_4238|M.marinum_M VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MUL_0949|M.ulcerans_Agy99 VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MAV_4627|M.avium_104 TIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAFALFGTKKL
Mflv_2381|M.gilvum_PYR-GCK TVASLVGIVLIPPLGALSDRIGRKSLLIAGAVAFAVFAYPLFLLLNTGSL
Mvan_4266|M.vanbaalenii_PYR-1 TVASLVGIVLIPPLGALSDRVGRKPLLLAGSIGFAVFAYPLFLLLNTGSL
TH_3400|M.thermoresistible__bu IIGMLSMMVFLPFAGLLSDRFGRKPMWWISLGGLLALVVPMFMLMST-SV
MLBr_01562|M.leprae_Br4923 IPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGVP
: . : .:.. : : :
MAB_3808c|M.abscessus_ATCC_199 PIVSFLLVAVSYVLLTGYTSINALVKSELFPSHVRALGVGVGYALANSVF
MSMEG_0985|M.smegmatis_MC2_155 AIMSFLLVAGGYIILTGYTSINAVVKAELFPSHIRALGVGVGYALANSLV
Mb3503c|M.bovis_AF2122/97 PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
Rv3476c|M.tuberculosis_H37Rv PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
MMAR_4238|M.marinum_M VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MUL_0949|M.ulcerans_Agy99 VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MAV_4627|M.avium_104 LWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLSFVYQFSGVYA
Mflv_2381|M.gilvum_PYR-GCK AAAIAAHAALA-AIESVFVSASLAAGAELFATKVRSSGYSIGYNVSVAVF
Mvan_4266|M.vanbaalenii_PYR-1 AAAIAAHAALA-AIEAVFVCASLAAGAELFATRVRSSGYSIGYNVSVAIF
TH_3400|M.thermoresistible__bu PGAIIGFAVLG-LLYVPQLATISATFPAMFPTHVRYAGFAIAYNVSTSLF
MLBr_01562|M.leprae_Br4923 YFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQSLG
: . * . .
MAB_3808c|M.abscessus_ATCC_199 GGTAPLIYQALKEH------------------------DQVPLFIGYVTV
MSMEG_0985|M.smegmatis_MC2_155 GGTAPVIYQALKER------------------------DQVPLFIGYVTV
Mb3503c|M.bovis_AF2122/97 GGTAPLIYQALKER------------------------DQVPMFIAYVTA
Rv3476c|M.tuberculosis_H37Rv GGTAPLIYQALKER------------------------DQVPMFIAYVTA
MMAR_4238|M.marinum_M GAAPPLIAGTLLAS------------------------YGSS-AVGLMMT
MUL_0949|M.ulcerans_Agy99 GAAPPLIAGTLLAS------------------------YGSS-AVGLMMT
MAV_4627|M.avium_104 SGVTPMILTALIAA------------------------LGG--APWLACG
Mflv_2381|M.gilvum_PYR-GCK GGTAPYVATWLVSR------------------------TGNDIAPAYYLI
Mvan_4266|M.vanbaalenii_PYR-1 GGTAPYVATWLVSR------------------------TGNDIAPAFYVI
TH_3400|M.thermoresistible__bu GGTAPAANDWLIQQ------------------------TGNNLMPAFYMM
MLBr_01562|M.leprae_Br4923 GPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLLWVAG
. :
MAB_3808c|M.abscessus_ATCC_199 CIAISLVVYLFFLKNKSQTYLDREQGSAFNR-------------
MSMEG_0985|M.smegmatis_MC2_155 CIAISLVVYLFYLKNKSETYLDREKGAAFVR-------------
Mb3503c|M.bovis_AF2122/97 CIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-----------
Rv3476c|M.tuberculosis_H37Rv CIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-----------
MMAR_4238|M.marinum_M ALVAASLLCTYLLPETAGAPLTAA--------------------
MUL_0949|M.ulcerans_Agy99 ALVAASLLCTYLLPETAGAPLTAA--------------------
MAV_4627|M.avium_104 YLVATAVISVLATALIRDRDLYL---------------------
Mflv_2381|M.gilvum_PYR-GCK AAAIVSLLTVLTMRETARKPLR----------------KLVHP-
Mvan_4266|M.vanbaalenii_PYR-1 AAAVVTFLTVLTMRETARQPLR----------------KLVSD-
TH_3400|M.thermoresistible__bu AACLVGMLALVKLPETARCPIGGTEIPGTEDAPPPVEYDLVGNR
MLBr_01562|M.leprae_Br4923 AVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL----------
.