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LAATNATSPASAAPPTSRRTMLALGLGNTLEWYDWMIFGLLAAYLGPQFFAPQDSVSATLDTLAVFAVGF VMRPLGGVLLGNLADRIGRRRVMLLSVSLMAVTTLVIAVMPTYDTIGVWAGVLLLVLRILQGVSTGIEAP LSTAYAVEVNPAGHEGRAAGYISFFVNFGILLASLVSFLTSYFLGGDEMAAWGWRVPMLFGAAMGFFVLY LRRTLPETLHDEEKAEQNAGTWGGVLKHWIGLLAMIFVVGAAQAYNYAWNVGLPSLARSTFNEDPTRIFA ATTAFGVILLIGSIVTGRLADRITLSKAFIGTRLLAIPAVFMMLLYAGPGMSTFTVVLLVGGVFLVANMT LYNVVSTSLMPKYCRATGTSLGYGLAVAAFGGTASYLLVWLQRIGQLWVFPAYTATLAAISVVLYVIARR KSGIFAGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1152 | - | - | 100% (428) | citrate-proton symporter |
| M. smegmatis MC2 155 | MSMEG_2952 | - | 2e-68 | 36.89% (412) | transport gene |
| M. smegmatis MC2 155 | MSMEG_3990 | - | 2e-59 | 32.06% (418) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3503c | kgtP | 6e-45 | 29.43% (401) | dicarboxylic acid transport integral membrane protein KgtP |
| M. gilvum PYR-GCK | Mflv_2381 | - | 2e-55 | 32.55% (424) | general substrate transporter |
| M. tuberculosis H37Rv | Rv3476c | kgtP | 2e-45 | 29.68% (401) | dicarboxylic acid transport integral membrane protein KgtP |
| M. leprae Br4923 | MLBr_01562 | - | 5e-11 | 24.19% (310) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_3808c | - | 9e-45 | 28.74% (428) | dicarboxylic acid transport integral membrane protein KgtP |
| M. marinum M | MMAR_4238 | - | 4e-32 | 30.02% (423) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 2e-37 | 29.86% (422) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_3722 | - | 7e-51 | 31.22% (426) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 3e-32 | 30.02% (423) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_4266 | - | 4e-55 | 32.94% (422) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3503c|M.bovis_AF2122/97 ---------------------------MTVSIAPPSRPS-QAETRRAIWN
Rv3476c|M.tuberculosis_H37Rv ---------------------------MTVSIAPPSRPS-QAETRRAIWN
MAB_3808c|M.abscessus_ATCC_199 ---------------------------MAVSAADTSTPSGRAQTRRAIWN
Mflv_2381|M.gilvum_PYR-GCK ----------------------------MTVDEDQR-RPSGAEPAAVRQA
Mvan_4266|M.vanbaalenii_PYR-1 ----------------------------MTVKET---RP--AAPGAVSRA
TH_3722|M.thermoresistible__bu ----------------------------VSENPSIVSAPPAPDAVVIRKA
MMAR_4238|M.marinum_M ----------------------------------------------MSRV
MUL_0949|M.ulcerans_Agy99 ----------------------------------------------MSRV
MAV_4627|M.avium_104 -----------------MAATLPAPAPAGLADGHPLDESAEQQRRRLRIV
MSMEG_1152|M.smegmatis_MC2_155 ------------------------------MAATNATSPASAAPPTSRRT
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb3503c|M.bovis_AF2122/97 TIRGSSGNLVEWYDVYVYTVFATYFEDQFFDRA--DRNSTVYVYAIFAVT
Rv3476c|M.tuberculosis_H37Rv TIRGSSGNLVEWYDVYVYTVFATYFEDQFFDRA--DRNSTVYVYAIFAVT
MAB_3808c|M.abscessus_ATCC_199 TIRGSSGNLVEWYDVYVYTVFAMYFEKQFFDDS--DQNSTVYVYAIFAVT
Mflv_2381|M.gilvum_PYR-GCK VRGAAIGNTVEWFDFAIYGFLATYIADKFFPSG-DETAALLSTFAVFAAA
Mvan_4266|M.vanbaalenii_PYR-1 VRGAAIGNAVEWFDFAIYGFLATYIAEKFFPPG-DETAALLNTFAIFAAA
TH_3722|M.thermoresistible__bu VTGASIGNAVEWFDFAIYGFLATYIAANFFPAG-DDTAALLNTFAIFAAA
MMAR_4238|M.marinum_M ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MUL_0949|M.ulcerans_Agy99 ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MAV_4627|M.avium_104 VAASLLGTTVEWYDFFLYATAAGLVFNKVFFPNESSLVGTLLAFATFAVG
MSMEG_1152|M.smegmatis_MC2_155 MLALGLGNTLEWYDWMIFGLLAAYLGPQFFAPQ-DSVSATLDTLAVFAVG
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
. : . : . : . .
Mb3503c|M.bovis_AF2122/97 FVTRPVGSWFFG-RFADRRGRRAALTFSVSLMAAC---------SLIVAL
Rv3476c|M.tuberculosis_H37Rv FVTRPVGSWFLG-RFADRRGRRAALTFSVSLMAAC---------SLIVAL
MAB_3808c|M.abscessus_ATCC_199 FITRPLGSWFFG-RFADRNGRRAALTLSVSLMAAC---------SMVIAL
Mflv_2381|M.gilvum_PYR-GCK FFMRPLGGFFFG-PLGDRIGRQRVLAIVILLMSAS---------TLAIGL
Mvan_4266|M.vanbaalenii_PYR-1 FFMRPLGGFFFG-PLGDRIGRQRVLALVILLMSAS---------TLAIGL
TH_3722|M.thermoresistible__bu FVVRPLGGFFFG-PLGDRIGRQRVLALVILLMSGA---------TLTMGL
MMAR_4238|M.marinum_M FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALS---------TVTVGV
MUL_0949|M.ulcerans_Agy99 FLSRPLGAAVFG-HFGDRLGRKKTLVATLLIMALS---------TVTVGV
MAV_4627|M.avium_104 FVMRPIGGLVFG-HIGDRIGRKRSLALTMLIMGGA---------TALIGV
MSMEG_1152|M.smegmatis_MC2_155 FVMRPLGGVLLG-NLADRIGRRRVMLLSVSLMAVT---------TLVIAV
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
:. * .:* :.* **: : : :: : :
Mb3503c|M.bovis_AF2122/97 VPSRSSIGVAAPILLILCRLVQGFATG-GEYGTSVTYMSEAATRERRGYF
Rv3476c|M.tuberculosis_H37Rv VPSRSSIGVAAPILLILCRLVQGFATG-GEYGTSATYMSEAATRERRGYF
MAB_3808c|M.abscessus_ATCC_199 VPSRGSIGMAAPIVLILCRLVQGFATG-GEYGTSATYMSEAATRERRGFF
Mflv_2381|M.gilvum_PYR-GCK VPSYDSIGVLAPILLLVLRCLQGFSAG-GEYGSGACFLAEYAPNRHRGFV
Mvan_4266|M.vanbaalenii_PYR-1 VPGYDSIGVLAPILLLLLRCLQGFSAG-GEYGSGACFLAEYAPDRHRGFV
TH_3722|M.thermoresistible__bu LPTYESIGVLAPLLLLLLRCLQGFSAG-GEYGGGAVYLAEFAPDRRRGLI
MMAR_4238|M.marinum_M VPSTATIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MUL_0949|M.ulcerans_Agy99 VPSTATIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGYY
MAV_4627|M.avium_104 LPTAAQIGAWAPVLLLVLRVLQGFALG-GEWGGAVLLAVEHSPGDRRGRY
MSMEG_1152|M.smegmatis_MC2_155 MPTYDTIGVWAGVLLLVLRILQGVSTG-IEAPLSTAYAVEVNPAGHEGRA
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
** .: * . . *
Mb3503c|M.bovis_AF2122/97 SSFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGAAI
Rv3476c|M.tuberculosis_H37Rv SSFQYVTLVGGHVLAQFTLLVILAVFT--REQVHEFGWRIGFAVGGGAAI
MAB_3808c|M.abscessus_ATCC_199 SSFQYVTLVGGHVLAQFTLLIILTVFD--TAQVHEFGWRIAFATGGVAAI
Mflv_2381|M.gilvum_PYR-GCK VSFLVWSVVVGFLAGAITVTALETWLS--EDAMNSYGWRIPFMIAGLLGA
Mvan_4266|M.vanbaalenii_PYR-1 VSFLVWSVVVGFLLGSVTVTALEATLS--ESAMNSFGWRIPFLIAGALGA
TH_3722|M.thermoresistible__bu VTFMAWSGVLGFLLGSVTVTALQVALP--DQVMTDVGWRIPFLLAGPLGL
MMAR_4238|M.marinum_M GMFTVLGGGVALVVSGLTFLGVNYTIGESSSAFLQWGWRVPFLLSALLIA
MUL_0949|M.ulcerans_Agy99 GMFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWRVPFLLSALLIA
MAV_4627|M.avium_104 GAVPQVGLALGLALGTGIFAFLQIVLG--PARFLSYGWRIGFLLSVLLVA
MSMEG_1152|M.smegmatis_MC2_155 AGYISFFVNFGILLASLVSFLTSYFLG--GDEMAAWGWRVPMLFGAAMGF
MLBr_01562|M.leprae_Br4923 VGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILA
*: : .
Mb3503c|M.bovis_AF2122/97 VVFWLRRTMDESLSQER---LTAIKAGRDHDSGSLRELAT----------
Rv3476c|M.tuberculosis_H37Rv VVFWLRRTMDESLSQER---LTAIKAGRDHDSGSLRELAT----------
MAB_3808c|M.abscessus_ATCC_199 VVYWLRRTMDESLSEEQ---LAAIKAGADTSSGSMRELLT----------
Mflv_2381|M.gilvum_PYR-GCK VGLYIRLKLGDTPEFR------SLRESGEVSQSPLREAVT----------
Mvan_4266|M.vanbaalenii_PYR-1 VGLYIRLRLGDTPEFE------ALRESGEVSTTPLKEAVT----------
TH_3722|M.thermoresistible__bu IGLYIRLRLDDTPAFT------ALSEQEEVAQSPLREAVQ----------
MMAR_4238|M.marinum_M FALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC----------
MUL_0949|M.ulcerans_Agy99 FALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC----------
MAV_4627|M.avium_104 IGIVVRLRVEETPAFR------ELQDLQAASTVPIRDILRER--------
MSMEG_1152|M.smegmatis_MC2_155 FVLYLRRTLPETLHDE---------EKAEQNAGTWGGVLK----------
MLBr_01562|M.leprae_Br4923 TLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVV
. : .
Mb3503c|M.bovis_AF2122/97 ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
Rv3476c|M.tuberculosis_H37Rv ----HYWKPLLLCFLVTLGGTVAFYTYSVNAPAIVKSVYGSQAMTATWIN
MAB_3808c|M.abscessus_ATCC_199 ----RYRKPLLLCFLITMGGTLAFYTYSVNAPAIVKAAYKDQAMTATWIN
Mflv_2381|M.gilvum_PYR-GCK ----TSWRPILQIIGLVVIHNVGFYIVYTFLPSYFTETLDFSKVDAFWSI
Mvan_4266|M.vanbaalenii_PYR-1 ----TSWRPILQIIGLVVVHNVGFYVVYTFLPSYFTRTLEFSKIDAFYSI
TH_3722|M.thermoresistible__bu ----TAWRSILQVIGLMIIFNVAYYVVFAYMPTYLIKELGLSSSDAFISS
MMAR_4238|M.marinum_M ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MUL_0949|M.ulcerans_Agy99 ----RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIG
MAV_4627|M.avium_104 ----RSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALGLNRVSVLIAV
MSMEG_1152|M.smegmatis_MC2_155 -----HWIGLLAMIFVVGAAQAYNYAWNVGLPSLARSTFNEDPTRIFAAT
MLBr_01562|M.leprae_Br4923 PFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGF
: . .
Mb3503c|M.bovis_AF2122/97 LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
Rv3476c|M.tuberculosis_H37Rv LVGLILLMMLQPIGGMISDKIGRKPLLLWFGVGGLIYTYVLVTYLPETRS
MAB_3808c|M.abscessus_ATCC_199 LAGLIFLMLLQPVGGIISDKVGRKPLLLFFGFGGVVYTYVLITYLPQVHA
Mflv_2381|M.gilvum_PYR-GCK TVASLVGIVLIPPLGALSDRIGRKSLLIAGAVAFAVFAYPLFLLLNTGSL
Mvan_4266|M.vanbaalenii_PYR-1 TVASLVGIVLIPPLGALSDRVGRKPLLLAGSIGFAVFAYPLFLLLNTGSL
TH_3722|M.thermoresistible__bu TIACVVALVLILPLAALSDRIGRKPLLVGGAIAFAVLAYPLFLLLNSGST
MMAR_4238|M.marinum_M VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MUL_0949|M.ulcerans_Agy99 VLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDT
MAV_4627|M.avium_104 TIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAFALFGTKKL
MSMEG_1152|M.smegmatis_MC2_155 TAFGVILLIGSIVTGRLADRITLSKAFIGTRLLAIPAVFMMLLYAGPGMS
MLBr_01562|M.leprae_Br4923 IPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRG-V
: . : .:. :
Mb3503c|M.bovis_AF2122/97 PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
Rv3476c|M.tuberculosis_H37Rv PTMSFLLVAVGYVILTGYCSINALVKSELFPAHVRALGVGVGYALANSVF
MAB_3808c|M.abscessus_ATCC_199 PIVSFLLVAVSYVLLTGYTSINALVKSELFPSHVRALGVGVGYALANSVF
Mflv_2381|M.gilvum_PYR-GCK AAAIAAHAALA-AIESVFVSASLAAGAELFATKVRSSGYSIGYNVSVAVF
Mvan_4266|M.vanbaalenii_PYR-1 AAAIAAHAALA-AIEAVFVCASLAAGAELFATRVRSSGYSIGYNVSVAIF
TH_3722|M.thermoresistible__bu AAAMIAHAGLA-AIESVVISVAVVTAVEQFTTRVRYSGMSVGYNVCVALF
MMAR_4238|M.marinum_M VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MUL_0949|M.ulcerans_Agy99 VGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTALALNVAGIVG
MAV_4627|M.avium_104 LWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLSFVYQFSGVYA
MSMEG_1152|M.smegmatis_MC2_155 TFTVVLLVGGVFLVAN--MTLYNVVSTSLMPKYCRATGTSLGYGLAVAAF
MLBr_01562|M.leprae_Br4923 PYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQSL
* .
Mb3503c|M.bovis_AF2122/97 GGTAPLIYQALKER-------------------------DQVPMFIAYVT
Rv3476c|M.tuberculosis_H37Rv GGTAPLIYQALKER-------------------------DQVPMFIAYVT
MAB_3808c|M.abscessus_ATCC_199 GGTAPLIYQALKEH-------------------------DQVPLFIGYVT
Mflv_2381|M.gilvum_PYR-GCK GGTAPYVATWLVSR-------------------------TGNDIAPAYYL
Mvan_4266|M.vanbaalenii_PYR-1 GGTAPYVATWLVSR-------------------------TGNDIAPAFYV
TH_3722|M.thermoresistible__bu GGTTPYVMTWLIDT-------------------------TANPLAPACAV
MMAR_4238|M.marinum_M GAAPPLIAGTLLAS-------------------------YGSS-AVGLMM
MUL_0949|M.ulcerans_Agy99 GAAPPLIAGTLLAS-------------------------YGSS-AVGLMM
MAV_4627|M.avium_104 SGVTPMILTALIAA-------------------------LGG--APWLAC
MSMEG_1152|M.smegmatis_MC2_155 GGTASYLLVWLQRI-------------------------GQLWVFPAYTA
MLBr_01562|M.leprae_Br4923 GGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLLWVA
..
Mb3503c|M.bovis_AF2122/97 ACIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-
Rv3476c|M.tuberculosis_H37Rv ACIAVSLIVYVFFIKNKADTYLDREQGFAFYGHA-
MAB_3808c|M.abscessus_ATCC_199 VCIAISLVVYLFFLKNKSQTYLDREQGSAFNR---
Mflv_2381|M.gilvum_PYR-GCK IAAAIVSLLTVLTMRETARKPLRKLVHP-------
Mvan_4266|M.vanbaalenii_PYR-1 IAAAVVTFLTVLTMRETARQPLRKLVSD-------
TH_3722|M.thermoresistible__bu TLAAVVSLGVVMTLRETAARPLAGTP---------
MMAR_4238|M.marinum_M TALVAASLLCTYLLPETAGAPLTAA----------
MUL_0949|M.ulcerans_Agy99 TALVAASLLCTYLLPETAGAPLTAA----------
MAV_4627|M.avium_104 GYLVATAVISVLATALIRDRDLYL-----------
MSMEG_1152|M.smegmatis_MC2_155 TLAAISVVLYVIARRKSGIFAGK------------
MLBr_01562|M.leprae_Br4923 GAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL
. .