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PDLQAESPIAPSRYAGRRVLITGGGSGIGQACVLRILAEGAQVVAADISPEGLDDTTGKAGEFSSRLTTV TLDVGDEDSVRAGVAAAVAELGGLDTLVNAAGILRSSHLAQTSLADFEQVLRINLTGTFLVTREAIGALL EGHRPAVVNFSSTSAHFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNSVQPGSISSGMTDGTGASR QSIGPGLPEDADFSLFGKVAPMLPLDGGAIFARPDAVAGVVAMLGSADAYFITGTEVRIDGGSHM*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2852 | - | - | 100% (276) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 1e-32 | 33.85% (260) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_3607 | - | 2e-29 | 33.08% (260) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 3e-32 | 33.85% (260) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4541 | - | 1e-124 | 84.03% (263) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1941 | - | 3e-32 | 33.85% (260) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-23 | 29.29% (280) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0827 | - | 2e-29 | 33.59% (259) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4967 | - | 1e-77 | 58.21% (268) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_0672 | - | 7e-79 | 58.05% (267) | oxidoreductase |
| M. thermoresistible (build 8) | TH_2959 | - | 1e-119 | 81.06% (264) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_4041 | - | 4e-78 | 58.21% (268) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_2848 | - | 1e-122 | 84.85% (264) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1976|M.bovis_AF2122/97 -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Mflv_4541|M.gilvum_PYR-GCK ----------------MRYSGRRVLITGGGSGIGQACALRILAEGGRVAA
Mvan_2848|M.vanbaalenii_PYR-1 ----MSATPTGSSPQLTRYAGRRVLITGGGSGIGQACVLRILAEGGRVVA
MSMEG_2852|M.smegmatis_MC2_155 ----MPDLQAESPIAPSRYAGRRVLITGGGSGIGQACVLRILAEGAQVVA
TH_2959|M.thermoresistible__bu -----------VSDLSARYAARRVLITGGGSGIGQACVLRILAEGGRVAA
MMAR_4967|M.marinum_M ---------------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVG
MUL_4041|M.ulcerans_Agy99 ---------------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVG
MAV_0672|M.avium_104 ---------------MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAA
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0827|M.abscessus_ATCC_1997 MTSPLK--------------SRRAFVTGGSRGIGAGIVRRLAEDGARVVF
.: ::**. *** . . *: :* *
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGG
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGG
Mflv_4541|M.gilvum_PYR-GCK ADISGDGLADTVQKAGDLAT--NLMTVVMDVGDEPSVSSGVAEAIAALGG
Mvan_2848|M.vanbaalenii_PYR-1 ADISADGLADTAEKAGALGT--GLSTVVMDVGDEQSVSAGLAEALNTLGG
MSMEG_2852|M.smegmatis_MC2_155 ADISPEGLDDTTGKAGEFSS--RLTTVTLDVGDEDSVRAGVAAAVAELGG
TH_2959|M.thermoresistible__bu ADISPSGLRDTVNQAGAAAE--RLTTVTMDVADEQSVRHGVGQAITALGG
MMAR_4967|M.marinum_M ADIDAAGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGG
MUL_4041|M.ulcerans_Agy99 ADIDADGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGG
MAV_0672|M.avium_104 SDVAVDGLERTRDRAAQAGTAERLVTVTMDVGREDAVVDGVRVAVEQLGG
MLBr_01807|M.leprae_Br4923 THRASVVP-------------DWFFGVECDVTDNDAIGAAFKAVEEHQGP
MAB_0827|M.abscessus_ATCC_1997 TYSSSVQQAADVVDDINEDG-GWARAVKADVADPDQLGAAIGQAAEELGG
: ** : . *
Mb1976|M.bovis_AF2122/97 VDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERG
Rv1941|M.tuberculosis_H37Rv VDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERG
Mflv_4541|M.gilvum_PYR-GCK LDTLVNAAGILRSAHLADTTLADFEQVLRINLIGTFLVTRESLAALRDGR
Mvan_2848|M.vanbaalenii_PYR-1 LDTLVNAAGILRSAHLAQTTLADFEQVLRINLIGTFLVTREAVTALHQGD
MSMEG_2852|M.smegmatis_MC2_155 LDTLVNAAGILRSSHLAQTSLADFEQVLRINLTGTFLVTREAIGALLEGH
TH_2959|M.thermoresistible__bu LDALVNAAGILRSAHLVQTTLADFEQVIRINLTGTFLVTRECIPALLDGN
MMAR_4967|M.marinum_M LDALVNAAGMLRAAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQ
MUL_4041|M.ulcerans_Agy99 LDALVNAAGMLRAAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQ
MAV_0672|M.avium_104 LDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGTFLVVREALPALLDNA
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_0827|M.abscessus_ATCC_1997 LDILVNNAGILSIGDVDTATLADFDEIVAVNVRAVFAGIKAASPHLTEG-
:: ** **: : ::.:: :*: ..: : . : .
Mb1976|M.bovis_AF2122/97 GGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNT
Rv1941|M.tuberculosis_H37Rv GGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNT
Mflv_4541|M.gilvum_PYR-GCK GPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNC
Mvan_2848|M.vanbaalenii_PYR-1 GSAVVNFSSTSA-QFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNC
MSMEG_2852|M.smegmatis_MC2_155 RPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNS
TH_2959|M.thermoresistible__bu GPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHTWAAEFAKAGIRFNA
MMAR_4967|M.marinum_M RSTVVNFSSTSA-AFAHPYMAAYAASKGGVQAFTHSLALEYARDGLRAVC
MUL_4041|M.ulcerans_Agy99 RSTVVNFSSTSA-AFAHPYMAAYAASKGGVQAFTHSLALEYARDGLRAVC
MAV_0672|M.avium_104 RSAVVNFSSTSA-SFAHPYMAAYAASKGGIQAFTHSLALEYARRGLRAVC
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
MAB_0827|M.abscessus_ATCC_1997 -GRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPRGITINN
: :.* . . *. :*..: ::: * * .:
Mb1976|M.bovis_AF2122/97 LLPAFVDTPMQQTAMAMFDG---ALGAGGARSMIARLQ-----------G
Rv1941|M.tuberculosis_H37Rv LLPAFVDTPMQQTAMAMFDG---ALGAGGARSMIARLQ-----------G
Mflv_4541|M.gilvum_PYR-GCK VQPGSISSGMTDGTGASRQSVGPGLPEDADYALFGKVAPMLP---LDDGA
Mvan_2848|M.vanbaalenii_PYR-1 VQPGSISSGMTDGTGASRQSIGPGLPEDADYTLFAKVAPMLP---LDGGA
MSMEG_2852|M.smegmatis_MC2_155 VQPGSISSGMTDGTGASRQSIGPGLPEDADFSLFGKVAPMLP---LDGGA
TH_2959|M.thermoresistible__bu VQPGSISSGMTDGSGVSRQSVGPGLPEDADLALFAKVAPALP---LGDGT
MMAR_4967|M.marinum_M VAPGSIKSGITDATGG-------YIPADANWSLFTRLMPILPTTETSSGA
MUL_4041|M.ulcerans_Agy99 VAPGSIKSGITDATGG-------YIPADANWSLFTRLMPILPTTETSSGA
MAV_0672|M.avium_104 VAPGSIKSGITDATGG-------YIPEDADWSLFSRLLPVLPTTVESSGT
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTR-------------AMDSKYQEAALQAIPLG--------
MAB_0827|M.abscessus_ATCC_1997 VQPGPIGTDMN--------------PEDGQLADILRPNIAVG--------
: *. : : : ..
Mb1976|M.bovis_AF2122/97 RMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Rv1941|M.tuberculosis_H37Rv RMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Mflv_4541|M.gilvum_PYR-GCK IFAAPDAVAGVVAMLGSSDAYFITGTEVRIDGGSHM---
Mvan_2848|M.vanbaalenii_PYR-1 IFAAPDAVAGVVAMLGSRDAYFITGTEVRIDGGSHM---
MSMEG_2852|M.smegmatis_MC2_155 IFARPDAVAGVVAMLGSADAYFITGTEVRIDGGSHM---
TH_2959|M.thermoresistible__bu IFADPDAVAGVVAMLGSDDAFFITGTEVRIDGGAHM---
MMAR_4967|M.marinum_M GMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MUL_4041|M.ulcerans_Agy99 GMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MAV_0672|M.avium_104 GMAEPTAVAGVIAMLVSDDGAFITGTEIRIDGGTHA---
MLBr_01807|M.leprae_Br4923 RIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
MAB_0827|M.abscessus_ATCC_1997 RYGQPRDIASLVSYLVSDEAWYITGTAINIDGGFTA---
. :*. : * * :. *:*: ***