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M. thermoresistible (build 8) TH_2959 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 852738 - 853547
length: 270

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2959--100% (270)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3954-8e-3333.58% (265) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase
M. thermoresistible (build 8)TH_3693-1e-3132.18% (261) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1976-2e-3333.59% (259) short-chain type dehydrogenase/reductase
M. gilvum PYR-GCKMflv_4541-1e-12082.89% (263) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1941-2e-3333.59% (259) short-chain type dehydrogenase/reductase
M. leprae Br4923MLBr_01807fabG16e-2227.86% (262) 3-oxoacyl-
M. abscessus ATCC 19977MAB_0827-3e-3034.10% (261) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4967-2e-7657.84% (268) short-chain type dehydrogenase/reductase
M. avium 104MAV_0672-3e-7758.58% (268) oxidoreductase
M. smegmatis MC2 155MSMEG_2852-1e-11981.06% (264) 3-oxoacyl-
M. ulcerans Agy99MUL_4041-2e-7657.84% (268) short-chain type dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_2848-1e-11680.61% (263) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1976|M.bovis_AF2122/97            -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv         -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Mflv_4541|M.gilvum_PYR-GCK          ----------------MRYSGRRVLITGGGSGIGQACALRILAEGGRVAA
Mvan_2848|M.vanbaalenii_PYR-1       ----MSATPTGSSPQLTRYAGRRVLITGGGSGIGQACVLRILAEGGRVVA
MSMEG_2852|M.smegmatis_MC2_155      ----MPDLQAESPIAPSRYAGRRVLITGGGSGIGQACVLRILAEGAQVVA
TH_2959|M.thermoresistible__bu      -----------VSDLSARYAARRVLITGGGSGIGQACVLRILAEGGRVAA
MMAR_4967|M.marinum_M               ---------------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVG
MUL_4041|M.ulcerans_Agy99           ---------------MTRLVGQRILVTGAGSGIGQATVLRLLDEGATVVG
MAV_0672|M.avium_104                ---------------MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAA
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0827|M.abscessus_ATCC_1997      MTSPLK--------------SRRAFVTGGSRGIGAGIVRRLAEDGARVVF
                                                        .:  ::**.  *** . . *:  :*  *  

Mb1976|M.bovis_AF2122/97            ADIDGDAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGG
Rv1941|M.tuberculosis_H37Rv         ADIDGDAADAAATKIGCGAA-----ACRVDVSDEQQIIAMVDACVAAFGG
Mflv_4541|M.gilvum_PYR-GCK          ADISGDGLADTVQKAGDLAT--NLMTVVMDVGDEPSVSSGVAEAIAALGG
Mvan_2848|M.vanbaalenii_PYR-1       ADISADGLADTAEKAGALGT--GLSTVVMDVGDEQSVSAGLAEALNTLGG
MSMEG_2852|M.smegmatis_MC2_155      ADISPEGLDDTTGKAGEFSS--RLTTVTLDVGDEDSVRAGVAAAVAELGG
TH_2959|M.thermoresistible__bu      ADISPSGLRDTVNQAGAAAE--RLTTVTMDVADEQSVRHGVGQAITALGG
MMAR_4967|M.marinum_M               ADIDAAGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGG
MUL_4041|M.ulcerans_Agy99           ADIDADGLSRTQARTAEAGTGARLTTCQIDVADEKSVVDGVGAAVQALGG
MAV_0672|M.avium_104                SDVAVDGLERTRDRAAQAGTAERLVTVTMDVGREDAVVDGVRVAVEQLGG
MLBr_01807|M.leprae_Br4923          THRASVVP-------------DWFFGVECDVTDNDAIGAAFKAVEEHQGP
MAB_0827|M.abscessus_ATCC_1997      TYSSSVQQAADVVDDINEDG-GWARAVKADVADPDQLGAAIGQAAEELGG
                                    :                            **     :   .       * 

Mb1976|M.bovis_AF2122/97            VDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERG
Rv1941|M.tuberculosis_H37Rv         VDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERG
Mflv_4541|M.gilvum_PYR-GCK          LDTLVNAAGILRSAHLADTTLADFEQVLRINLIGTFLVTRESLAALRDGR
Mvan_2848|M.vanbaalenii_PYR-1       LDTLVNAAGILRSAHLAQTTLADFEQVLRINLIGTFLVTREAVTALHQGD
MSMEG_2852|M.smegmatis_MC2_155      LDTLVNAAGILRSSHLAQTSLADFEQVLRINLTGTFLVTREAIGALLEGH
TH_2959|M.thermoresistible__bu      LDALVNAAGILRSAHLVQTTLADFEQVIRINLTGTFLVTRECIPALLDGN
MMAR_4967|M.marinum_M               LDALVNAAGMLRAAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQ
MUL_4041|M.ulcerans_Agy99           LDALVNAAGMLRAAHTHQTSIQQWNQIIAVNLTGTFLVVREALPALLDNQ
MAV_0672|M.avium_104                LDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGTFLVVREALPALLDNA
MLBr_01807|M.leprae_Br4923          VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
MAB_0827|M.abscessus_ATCC_1997      LDILVNNAGILSIGDVDTATLADFDEIVAVNVRAVFAGIKAASPHLTEG-
                                    :: **  **:         :   ::.:: :*: ..:   : .   : .  

Mb1976|M.bovis_AF2122/97            GGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNT
Rv1941|M.tuberculosis_H37Rv         GGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNT
Mflv_4541|M.gilvum_PYR-GCK          GPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNC
Mvan_2848|M.vanbaalenii_PYR-1       GSAVVNFSSTSA-QFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNC
MSMEG_2852|M.smegmatis_MC2_155      RPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHAWALEFAKAGIRFNS
TH_2959|M.thermoresistible__bu      GPAVVNFSSTSA-HFAHPYMAAYAASKGGVLAMTHTWAAEFAKAGIRFNA
MMAR_4967|M.marinum_M               RSTVVNFSSTSA-AFAHPYMAAYAASKGGVQAFTHSLALEYARDGLRAVC
MUL_4041|M.ulcerans_Agy99           RSTVVNFSSTSA-AFAHPYMAAYAASKGGVQAFTHSLALEYARDGLRAVC
MAV_0672|M.avium_104                RSAVVNFSSTSA-SFAHPYMAAYAASKGGIQAFTHSLALEYARRGLRAVC
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
MAB_0827|M.abscessus_ATCC_1997      -GRIVTIGSINGDSSPTANLSLYSMTKAAVAGLTRGLAREFGPRGITINN
                                        : :.*  .        . *. :*..:  :::  * *    .:    

Mb1976|M.bovis_AF2122/97            LLPAFVDTPMQQTAMAMFDG---ALGAGGARSMIARLQ-----------G
Rv1941|M.tuberculosis_H37Rv         LLPAFVDTPMQQTAMAMFDG---ALGAGGARSMIARLQ-----------G
Mflv_4541|M.gilvum_PYR-GCK          VQPGSISSGMTDGTGASRQSVGPGLPEDADYALFGKVAPMLP---LDDGA
Mvan_2848|M.vanbaalenii_PYR-1       VQPGSISSGMTDGTGASRQSIGPGLPEDADYTLFAKVAPMLP---LDGGA
MSMEG_2852|M.smegmatis_MC2_155      VQPGSISSGMTDGTGASRQSIGPGLPEDADFSLFGKVAPMLP---LDGGA
TH_2959|M.thermoresistible__bu      VQPGSISSGMTDGSGVSRQSVGPGLPEDADLALFAKVAPALP---LGDGT
MMAR_4967|M.marinum_M               VAPGSIKSGITDATGG-------YIPADANWSLFTRLMPILPTTETSSGA
MUL_4041|M.ulcerans_Agy99           VAPGSIKSGITDATGG-------YIPADANWSLFTRLMPILPTTETSSGA
MAV_0672|M.avium_104                VAPGSIKSGITDATGG-------YIPEDADWSLFSRLLPVLPTTVESSGT
MLBr_01807|M.leprae_Br4923          VAPGFIDTEMTR-------------AMDSKYQEAALQAIPLG--------
MAB_0827|M.abscessus_ATCC_1997      VQPGPIGTDMN--------------PEDGQLADILRPNIAVG--------
                                    : *. : : :                 ..                     

Mb1976|M.bovis_AF2122/97            RMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Rv1941|M.tuberculosis_H37Rv         RMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Mflv_4541|M.gilvum_PYR-GCK          IFAAPDAVAGVVAMLGSSDAYFITGTEVRIDGGSHM---
Mvan_2848|M.vanbaalenii_PYR-1       IFAAPDAVAGVVAMLGSRDAYFITGTEVRIDGGSHM---
MSMEG_2852|M.smegmatis_MC2_155      IFARPDAVAGVVAMLGSADAYFITGTEVRIDGGSHM---
TH_2959|M.thermoresistible__bu      IFADPDAVAGVVAMLGSDDAFFITGTEVRIDGGAHM---
MMAR_4967|M.marinum_M               GMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MUL_4041|M.ulcerans_Agy99           GMADPSVVAGVIAMLVSEDGAFITGTEIRIDGGTHA---
MAV_0672|M.avium_104                GMAEPTAVAGVIAMLVSDDGAFITGTEIRIDGGTHA---
MLBr_01807|M.leprae_Br4923          RIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
MAB_0827|M.abscessus_ATCC_1997      RYGQPRDIASLVSYLVSDEAWYITGTAINIDGGFTA---
                                      .    :*. :  * * :.  *:*:    ***