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MTPGSNDPRPARSRARLLEAATVLLRSGGPSAVTVDAVTRAANVARATLYRHFPSGNDLLAAAFRQLIPA APTPPQEGTLRDRLIALVSAQAELIAEAPVTVTAMSWLALGADMEHLPLSASPEVLSLRERVAEQYAAPF EAIFTSPEAREELGDVDRAQAAALLLGPIVLGKLSTLPEFDYATCVRSAVDGFLATHRRTVSESSNESAG A
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1430 | - | - | 100% (211) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0986 | - | 3e-08 | 30.77% (169) | RemM protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 1e-07 | 46.03% (63) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 2e-10 | 37.00% (100) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_5054 | - | 2e-69 | 65.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 2e-10 | 37.00% (100) | regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 2e-05 | 40.68% (59) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 4e-08 | 29.90% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4834 | - | 1e-43 | 46.04% (202) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4473 | - | 1e-60 | 64.29% (182) | hypothetical protein MAV_4473 |
| M. thermoresistible (build 8) | TH_0409 | - | 3e-68 | 60.19% (216) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1934 | - | 2e-08 | 36.99% (73) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0323 | - | 1e-43 | 46.73% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 ----MVGAVTQIADRPTDPSPWSPRE-------TELLAVTLRLLQEHGYD
Rv1556|M.tuberculosis_H37Rv ----MVGAVTQIADRPTDPSPWSPRE-------TELLAVTLRLLQEHGYD
MUL_1934|M.ulcerans_Agy99 -----MGAMTQTADRSAQVSPWSPRE-------AELLAVTLQLLQEHGYD
MSMEG_1430|M.smegmatis_MC2_155 -----------MTPGSNDPRPARSR--------ARLLEAATVLLRSGGPS
MAV_4473|M.avium_104 --------------------------------------------------
Mflv_5054|M.gilvum_PYR-GCK -----------MAAVSSDPRPARSR--------ARLLDAATALLRSGGPS
TH_0409|M.thermoresistible__bu -----------MAAATSDPRPARSR--------ARLLEAATTLLRTGGPS
MMAR_4834|M.marinum_M -MERDTLEFPVDDDDDVDPRRLRSR--------TRLLDAATKLLSAGGIE
Mvan_0323|M.vanbaalenii_PYR-1 -MS-DSQSVPVPDDD-VDPRRIRSR--------TRLLDAAATLLSTGGVE
MAB_3462c|M.abscessus_ATCC_199 -----MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLHAADDLLVARGYA
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARN------RARILGVAYEAFATEG-L
Mb1581|M.bovis_AF2122/97 RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA----VPPNT
Rv1556|M.tuberculosis_H37Rv RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVA----VPPNT
MUL_1934|M.ulcerans_Agy99 RLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQVA----VAPNT
MSMEG_1430|M.smegmatis_MC2_155 AVTVDAVTRAANVARATLYRHFPSGNDLLAAAFRQLIPAAP----TPPQE
MAV_4473|M.avium_104 -MTVDAVTRTANVARATLYRHFPSGNDLLAAAFNSLIPASP----TPPAE
Mflv_5054|M.gilvum_PYR-GCK AVTIDAVTRKANVARATLYRHFPSANDLVAAAFVGLIPPPP----MPPST
TH_0409|M.thermoresistible__bu AVTIDAVTKSANVARATLYRHFAGANDLLAAAFTSLLEPAP----MPPAE
MMAR_4834|M.marinum_M AVTIDAVTKASKVARTTLYRHFSSSTQLLAATFERLLPQVH----PPPAT
Mvan_0323|M.vanbaalenii_PYR-1 AVTIDAVTKASKVARTTLYRHFHSSSHLLAATFERLLPQVTT---PAPTS
MAB_3462c|M.abscessus_ATCC_199 GVTMEGIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAACQL----DPPDL
MLBr_00316|M.leprae_Br4923 SVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKS
:.:: :: : .. *:** : : .:
Mb1581|M.bovis_AF2122/97 GNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALN---------
Rv1556|M.tuberculosis_H37Rv GNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALN---------
MUL_1934|M.ulcerans_Agy99 GSLRDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALS---------
MSMEG_1430|M.smegmatis_MC2_155 GTLRDRLIALVSAQA-ELIAEAP--VTVTAMSWLALGADMEHLPLS---A
MAV_4473|M.avium_104 GSLRDRLVAVVLAQA-EAVAQAP--TMMTAMTWLALGRDLEAWPQPRADD
Mflv_5054|M.gilvum_PYR-GCK GSLRERLLAIVVEWA-ESIAEAP--TTLTAMAWLSLGPDIEQVPSAGGSQ
TH_0409|M.thermoresistible__bu GSLRDRLLAVVLGWA-ETIAEAP--TMLTAMTWMASGPDVGPYPDARETD
MMAR_4834|M.marinum_M GSMRDQLIELLSRQA-TLFQEAP--LHVTTLAWVALGPTPDGTQETQDRH
Mvan_0323|M.vanbaalenii_PYR-1 GPLREQLIELLSRQA-ALFNDAP--LHVTTLAWLSLGPTGS-NNEADDRH
MAB_3462c|M.abscessus_ATCC_199 GGLEADLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLA---------
MLBr_00316|M.leprae_Br4923 AGPGEALFTYLRSLVLHWGATDR--GLVDALAGAGGIDILG---------
. * :
Mb1581|M.bovis_AF2122/97 ----DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLI
Rv1556|M.tuberculosis_H37Rv ----DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLI
MUL_1934|M.ulcerans_Agy99 ----DALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLI
MSMEG_1430|M.smegmatis_MC2_155 SPEVLSLRERVAEQYAAPFEAIFTSPEAREELGDVDRAQAAALLLGPIVL
MAV_4473|M.avium_104 SVAITTLRERIAQQYSEPFDVIFDSPEA-AELGEVDRSRAIALLIGPLVL
Mflv_5054|M.gilvum_PYR-GCK ---VGSLRERIAEQYSAPFDAVFDSPDAAAELRPVDRTMAFALLIGPLAF
TH_0409|M.thermoresistible__bu SDAVGTLRSRIVQLYSVPFDAILDSPQAAEELDEVDRIQTIALLIGPLIL
MMAR_4834|M.marinum_M -----ALRARIIDQYRQPFVALLQSPEARADLDDFDMELILCQLIGPVAF
Mvan_0323|M.vanbaalenii_PYR-1 T--SGALRARVVDQYRQPFDAILTSPKAQAELDDFDRELALCQLVGPLAF
MAB_3462c|M.abscessus_ATCC_199 ----DDFRGRYLREQQARDQIPIARAVARGELPADVDVAHVAEQLVAPLY
MLBr_00316|M.leprae_Br4923 -----VAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVG---C
:
Mb1581|M.bovis_AF2122/97 FRSIIPNRPPTQDTVQALVDDVILPSL---------TRSTG---------
Rv1556|M.tuberculosis_H37Rv FRSIIPNRPPTQDTVQALVDDVILPSL---------TRSTG---------
MUL_1934|M.ulcerans_Agy99 FRSIIPNRPPTPHTVQLLVDDFIMPGL---------TQATG---------
MSMEG_1430|M.smegmatis_MC2_155 GKLSTLPEFDYATCVRSAVDGFLATHR--RTVSESSNESAGA--------
MAV_4473|M.avium_104 GRLSTLPDFDYRECALAAVDGFLHVQS--ARARAARVESAGA--------
Mflv_5054|M.gilvum_PYR-GCK GRISTLTEFDYRAVAIAAVDGFLSTFS------ATNTGREGA--------
TH_0409|M.thermoresistible__bu GKLSTVADFDYRRCAEAAVDGFLATHAKKREITSASTESGGA--------
MMAR_4834|M.marinum_M ARLTGLRAIDRQDCER-IVDDFLVAHRRQADKPAQRAVSRKPVSRRSGSD
Mvan_0323|M.vanbaalenii_PYR-1 ARMTGIRTITHNDCAN-IVDDFLTAHR-KTDSDAK--ESKIATSRRAAPR
MAB_3462c|M.abscessus_ATCC_199 YRVIVTGETVDAAFVDRIVEDFLRRRE-----------------------
MLBr_00316|M.leprae_Br4923 QAMEAYNSALAERVTDVVVDGLRAAR------------------------
*:..
Mb1581|M.bovis_AF2122/97 -
Rv1556|M.tuberculosis_H37Rv -
MUL_1934|M.ulcerans_Agy99 -
MSMEG_1430|M.smegmatis_MC2_155 -
MAV_4473|M.avium_104 -
Mflv_5054|M.gilvum_PYR-GCK -
TH_0409|M.thermoresistible__bu -
MMAR_4834|M.marinum_M -
Mvan_0323|M.vanbaalenii_PYR-1 V
MAB_3462c|M.abscessus_ATCC_199 -
MLBr_00316|M.leprae_Br4923 -