For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TVDAVTRTANVARATLYRHFPSGNDLLAAAFNSLIPASPTPPAEGSLRDRLVAVVLAQAEAVAQAPTMMT AMTWLALGRDLEAWPQPRADDSVAITTLRERIAQQYSEPFDVIFDSPEAAELGEVDRSRAIALLIGPLVL GRLSTLPDFDYRECALAAVDGFLHVQSARARAARVESAGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4473 | - | - | 100% (181) | hypothetical protein MAV_4473 |
| M. avium 104 | MAV_3805 | - | 7e-31 | 41.76% (170) | putative transcriptional regulator |
| M. avium 104 | MAV_3866 | - | 3e-06 | 35.62% (73) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 1e-06 | 45.28% (53) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_5054 | - | 6e-55 | 63.53% (170) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 1e-06 | 45.28% (53) | regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4834 | - | 2e-28 | 41.21% (182) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1430 | - | 1e-60 | 64.29% (182) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0409 | - | 2e-61 | 65.22% (184) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1934 | - | 6e-07 | 43.64% (55) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0323 | - | 2e-29 | 42.77% (166) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4473|M.avium_104 -------------------------------------------MTVDAVT
MSMEG_1430|M.smegmatis_MC2_155 ----------MTPGSNDPRPARSR-ARLLEAATVLLRSGGPSAVTVDAVT
Mflv_5054|M.gilvum_PYR-GCK ----------MAAVSSDPRPARSR-ARLLDAATALLRSGGPSAVTIDAVT
TH_0409|M.thermoresistible__bu ----------MAAATSDPRPARSR-ARLLEAATTLLRTGGPSAVTIDAVT
MMAR_4834|M.marinum_M MERDTLEFPVDDDDDVDPRRLRSR-TRLLDAATKLLSAGGIEAVTIDAVT
Mvan_0323|M.vanbaalenii_PYR-1 MS-DSQSVPVPDDD-VDPRRIRSR-TRLLDAAATLLSTGGVEAVTIDAVT
Mb1581|M.bovis_AF2122/97 ---MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVA
Rv1556|M.tuberculosis_H37Rv ---MVGAVTQIADRPTDPSPWSPRETELLAVTLRLLQEHGYDRLTVDAVA
MUL_1934|M.ulcerans_Agy99 ----MGAMTQTADRSAQVSPWSPREAELLAVTLQLLQEHGYDRLTIDAVA
:*:***:
MAV_4473|M.avium_104 RTANVARATLYRHFPSGNDLLAAAFNSLIPASP-TPPAEGSLRDRLVAVV
MSMEG_1430|M.smegmatis_MC2_155 RAANVARATLYRHFPSGNDLLAAAFRQLIPAAP-TPPQEGTLRDRLIALV
Mflv_5054|M.gilvum_PYR-GCK RKANVARATLYRHFPSANDLVAAAFVGLIPPPP-MPPSTGSLRERLLAIV
TH_0409|M.thermoresistible__bu KSANVARATLYRHFAGANDLLAAAFTSLLEPAP-MPPAEGSLRDRLLAVV
MMAR_4834|M.marinum_M KASKVARTTLYRHFSSSTQLLAATFERLLPQVH-PPPATGSMRDQLIELL
Mvan_0323|M.vanbaalenii_PYR-1 KASKVARTTLYRHFHSSSHLLAATFERLLPQVTTPAPTSGPLREQLIELL
Mb1581|M.bovis_AF2122/97 ASARASKATVYRRWPSKAELVLAAFIEGIRQVA-VPPNTGNLRDDLLRLG
Rv1556|M.tuberculosis_H37Rv ASARASKATVYRRWPSKAELVLAAFIEGIRQVA-VPPNTGNLRDDLLRLG
MUL_1934|M.ulcerans_Agy99 NTARASKATVYRRWPSKAELVLAAFIEGVRQVA-VAPNTGSLRDDLVKIG
:..:::*:**:: . .*: *:* : .* * :*: *: :
MAV_4473|M.avium_104 LAQA-EAVAQAPTMMTAMTWLALGRDLEAWPQPRADDSVAITTLRERIAQ
MSMEG_1430|M.smegmatis_MC2_155 SAQA-ELIAEAPVTVTAMSWLALGADMEHLPLS---ASPEVLSLRERVAE
Mflv_5054|M.gilvum_PYR-GCK VEWA-ESIAEAPTTLTAMAWLSLGPDIEQVPSAGGSQ---VGSLRERIAE
TH_0409|M.thermoresistible__bu LGWA-ETIAEAPTMLTAMTWMASGPDVGPYPDARETDSDAVGTLRSRIVQ
MMAR_4834|M.marinum_M SRQA-TLFQEAPLHVTTLAWVALGPTPDGTQETQDRH-----ALRARIID
Mvan_0323|M.vanbaalenii_PYR-1 SRQA-ALFNDAPLHVTTLAWLSLGPTGS-NNEADDRHT--SGALRARVVD
Mb1581|M.bovis_AF2122/97 ELICREVGQHASTIRAVLVEVSRNPALN-------------DVLQHQFVD
Rv1556|M.tuberculosis_H37Rv ELICREVGQHASTIRAVLVEVSRNPALN-------------DVLQHQFVD
MUL_1934|M.ulcerans_Agy99 EGICGQAHQQASTIRAVLVEVSRHPALS-------------DALQRQFVD
. .*. :.: :: *: :. :
MAV_4473|M.avium_104 QYSEPFDVIFDSPEA-AELGEVDRSRAIALLIGPLVLGRLSTLPDFDYRE
MSMEG_1430|M.smegmatis_MC2_155 QYAAPFEAIFTSPEAREELGDVDRAQAAALLLGPIVLGKLSTLPEFDYAT
Mflv_5054|M.gilvum_PYR-GCK QYSAPFDAVFDSPDAAAELRPVDRTMAFALLIGPLAFGRISTLTEFDYRA
TH_0409|M.thermoresistible__bu LYSVPFDAILDSPQAAEELDEVDRIQTIALLIGPLILGKLSTVADFDYRR
MMAR_4834|M.marinum_M QYRQPFVALLQSPEARADLDDFDMELILCQLIGPVAFARLTGLRAIDRQD
Mvan_0323|M.vanbaalenii_PYR-1 QYRQPFDAILTSPKAQAELDDFDRELALCQLVGPLAFARMTGIRTITHND
Mb1581|M.bovis_AF2122/97 HRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQD
Rv1556|M.tuberculosis_H37Rv HRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQD
MUL_1934|M.ulcerans_Agy99 QRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTPH
: :: .. :: *: : :
MAV_4473|M.avium_104 CALAAVDGFLHVQS--ARARAARVESAGA---------
MSMEG_1430|M.smegmatis_MC2_155 CVRSAVDGFLATHR--RTVSESSNESAGA---------
Mflv_5054|M.gilvum_PYR-GCK VAIAAVDGFLSTFS------ATNTGREGA---------
TH_0409|M.thermoresistible__bu CAEAAVDGFLATHAKKREITSASTESGGA---------
MMAR_4834|M.marinum_M CER-IVDDFLVAHRRQADKPAQRAVSRKPVSRRSGSD-
Mvan_0323|M.vanbaalenii_PYR-1 CAN-IVDDFLTAHR-KTDSDAK--ESKIATSRRAAPRV
Mb1581|M.bovis_AF2122/97 TVQALVDDVILPSL---------TRSTG----------
Rv1556|M.tuberculosis_H37Rv TVQALVDDVILPSL---------TRSTG----------
MUL_1934|M.ulcerans_Agy99 TVQLLVDDFIMPGL---------TQATG----------
**..: