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ERDTLEFPVDDDDDVDPRRLRSRTRLLDAATKLLSAGGIEAVTIDAVTKASKVARTTLYRHFSSSTQLLA ATFERLLPQVHPPPATGSMRDQLIELLSRQATLFQEAPLHVTTLAWVALGPTPDGTQETQDRHALRARII DQYRQPFVALLQSPEARADLDDFDMELILCQLIGPVAFARLTGLRAIDRQDCERIVDDFLVAHRRQADKP AQRAVSRKPVSRRSGSD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4834 | - | - | 100% (228) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 2e-09 | 27.42% (186) | regulatory protein |
| M. marinum M | MMAR_2062 | - | 1e-06 | 46.30% (54) | hypothetical protein MMAR_2062 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 9e-11 | 25.00% (192) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_4579 | - | 1e-78 | 66.96% (224) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 9e-11 | 25.00% (192) | regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4352c | - | 1e-08 | 31.03% (116) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3805 | - | 3e-69 | 66.18% (207) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1430 | - | 2e-43 | 46.04% (202) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2910 | - | 2e-68 | 65.99% (197) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 1e-09 | 27.42% (186) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0323 | - | 2e-78 | 67.70% (226) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1581|M.bovis_AF2122/97 MVGAVTQIA-----------DRPTDPSPWSPRE-TELLAVTLRLLQEHGY
Rv1556|M.tuberculosis_H37Rv MVGAVTQIA-----------DRPTDPSPWSPRE-TELLAVTLRLLQEHGY
MUL_1934|M.ulcerans_Agy99 -MGAMTQTA-----------DRSAQVSPWSPRE-AELLAVTLQLLQEHGY
Mflv_4579|M.gilvum_PYR-GCK -MSDSQSVP---------VPDD--DVDPRRIRSRTRLLDAAATLLSTGGV
Mvan_0323|M.vanbaalenii_PYR-1 -MSDSQSVP---------VPDD--DVDPRRIRSRTRLLDAAATLLSTGGV
MAV_3805|M.avium_104 -MG-TQPAE---------TPDDEDDVDPRRTRSRTRLLDAAANLLKTGGI
MMAR_4834|M.marinum_M MERDTLEFP---------VDDD-DDVDPRRLRSRTRLLDAATKLLSAGGI
TH_2910|M.thermoresistible__bu -MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARLLDAATSLLTSGGV
MSMEG_1430|M.smegmatis_MC2_155 -MTPGS-------------------NDPRPARSRARLLEAATVLLRSGGP
MAB_4352c|M.abscessus_ATCC_199 -MVPLR--------------------QAQALATRQRLVDVATELFALHGF
.. .*: .: *: *
Mb1581|M.bovis_AF2122/97 DRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVP-PNTGN
Rv1556|M.tuberculosis_H37Rv DRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQVAVP-PNTGN
MUL_1934|M.ulcerans_Agy99 DRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQVAVA-PNTGS
Mflv_4579|M.gilvum_PYR-GCK EAVTIDAVTKASKVARTTLYRHFHSSSHLLAATFERLLPQVTTPAPTSGP
Mvan_0323|M.vanbaalenii_PYR-1 EAVTIDAVTKASKVARTTLYRHFHSSSHLLAATFERLLPQVTTPAPTSGP
MAV_3805|M.avium_104 EAVTIDAVTKASKVARTTLYRHFNSSSQLLAATFERLLPQVIPPAPTSGT
MMAR_4834|M.marinum_M EAVTIDAVTKASKVARTTLYRHFSSSTQLLAATFERLLPQVHPP-PATGS
TH_2910|M.thermoresistible__bu EAVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERLLPQVTSP-PATGD
MSMEG_1430|M.smegmatis_MC2_155 SAVTVDAVTRAANVARATLYRHFPSGNDLLAAAFRQLIPAAPTP-PQEGT
MAB_4352c|M.abscessus_ATCC_199 TSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVAEVNHSLT
:* ::: : :: ::*::: . .:: .* .
Mb1581|M.bovis_AF2122/97 LRDDLLRLG---ELICREVGQHASTIRAVLVEVSRN----PALNDV----
Rv1556|M.tuberculosis_H37Rv LRDDLLRLG---ELICREVGQHASTIRAVLVEVSRN----PALNDV----
MUL_1934|M.ulcerans_Agy99 LRDDLVKIG---EGICGQAHQQASTIRAVLVEVSRH----PALSDA----
Mflv_4579|M.gilvum_PYR-GCK LREQLIELLSRQAALFNDAPLHVTTLAWLSLGPTGS-NNEADDRHT-SVA
Mvan_0323|M.vanbaalenii_PYR-1 LREQLIELLSRQAALFNDAPLHVTTLAWLSLGPTGS-NNEADDRHT-SGA
MAV_3805|M.avium_104 LRERLIELLSRQADLFAEAPVQVTTLAWAALGPAET-HEPNTVQHAGAGT
MMAR_4834|M.marinum_M MRDQLIELLSRQATLFQEAPLHVTTLAWVALGPTPDGTQETQDRHA----
TH_2910|M.thermoresistible__bu LRDQLIELVHRQAALIDEAPLHLTALAWLALGPDPN----SDARQP-LAG
MSMEG_1430|M.smegmatis_MC2_155 LRDRLIALVSAQAELIAEAPVTVTAMSWLALGADMEHLPLSASPEV--LS
MAB_4352c|M.abscessus_ATCC_199 SIESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPM-----ALGWS----
: :. . : .
Mb1581|M.bovis_AF2122/97 LQHQFVDHRKAL--IQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSI
Rv1556|M.tuberculosis_H37Rv LQHQFVDHRKAL--IQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSI
MUL_1934|M.ulcerans_Agy99 LQRQFVDQRKAL--IQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSI
Mflv_4579|M.gilvum_PYR-GCK LRARVVDQYRQP--FDAILTSPKAQAELDDFDRELALCQLVGPLAFARMT
Mvan_0323|M.vanbaalenii_PYR-1 LRARVVDQYRQP--FDAILTSPKAQAELDDFDRELALCQLVGPLAFARMT
MAV_3805|M.avium_104 LRMRVIEQYRRP--FDEILYSPESVDQLGELDIELALCQLVGPLVFARMT
MMAR_4834|M.marinum_M LRARIIDQYRQP--FVALLQSPEARADLDDFDMELILCQLIGPVAFARLT
TH_2910|M.thermoresistible__bu LSARVIEQYRQP--FDELLAGAAARDELDDFDTTLAIIQLLGPIVFAKLT
MSMEG_1430|M.smegmatis_MC2_155 LRERVAEQYAAP--FEAIFTSPEAREELGDVDRAQAAALLLGPIVLGKLS
MAB_4352c|M.abscessus_ATCC_199 -RWRALDGGRSLGLIQDILEELYRRGELVEAVDPQMAAQLILGAINESGM
: : : :: :: . *:
Mb1581|M.bovis_AF2122/97 IPNRPPTQDTVQALVDDVILPSLTRSTG-------------------
Rv1556|M.tuberculosis_H37Rv IPNRPPTQDTVQALVDDVILPSLTRSTG-------------------
MUL_1934|M.ulcerans_Agy99 IPNRPPTPHTVQLLVDDFIMPGLTQATG-------------------
Mflv_4579|M.gilvum_PYR-GCK GIRTITHNDCAN-IVDDFLTAHRKTDSDAKESKIATKQTGRPARLAR
Mvan_0323|M.vanbaalenii_PYR-1 GIRTITHNDCAN-IVDDFLTAHRKTDSDAKESKIATSRRAAPRV---
MAV_3805|M.avium_104 GLRVITHQDCTR-IVEGFIAAQTGDQPAWVEASSPNQ----------
MMAR_4834|M.marinum_M GLRAIDRQDCER-IVDDFLVAHRRQADKPAQRAVSRKPVSRRSGSD-
TH_2910|M.thermoresistible__bu GMKTLTPADRVR-IVDDFLVAHRPPTPETA-----------------
MSMEG_1430|M.smegmatis_MC2_155 TLPEFDYATCVRSAVDGFLATHRRTVSESSNESAGA-----------
MAB_4352c|M.abscessus_ATCC_199 YAAAAPSERSSRAAEQLTLLCRGLLSPRSG-----------------
. : :