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TAVEDRPLRSDAARNVERILRAAREVYAELGPDAPVEAVARRAGVGERTLYRRFPAKADLVRAALDQSIA EDLTPVIDSARHAKDPLHGLTRLVEAAISLGAREQNLLAAAHRAGSLTSDISVSLNEALGELVREGQRAG RIRADLVADDLPRLVAMLYSVLSTMDAGSEGWRRYVALVVDAISVDERRPLPPAAALRYASQPNSWPL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2463 | - | - | 100% (209) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_4593 | - | 4e-12 | 33.33% (147) | TetR family protein transcriptional regulator |
| M. avium 104 | MAV_3923 | - | 1e-08 | 50.00% (62) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 3e-16 | 34.84% (155) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0142 | - | 8e-14 | 33.56% (149) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 3e-16 | 34.84% (155) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 5e-14 | 31.18% (186) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 5e-23 | 36.41% (195) | transcriptional regulator TetR |
| M. marinum M | MMAR_2833 | - | 1e-08 | 27.57% (185) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 5e-20 | 34.39% (189) | TetR-type regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 2e-08 | 28.65% (171) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_3399 | - | 1e-08 | 45.45% (66) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 4e-22 | 33.33% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0068c|M.bovis_AF2122/97 -----------------------------MAPTDRRVRADAARNRAR---
Rv0067c|M.tuberculosis_H37Rv -----------------------------MAPTDRRVRADAARNRAR---
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRAR---
MAB_0647|M.abscessus_ATCC_1997 -----------------------------MDQPARPLRADAARNRAR---
Mflv_0142|M.gilvum_PYR-GCK --------------------------------MTRPLRADAARNRAR---
MSMEG_3807|M.smegmatis_MC2_155 -----------------------------MTSSVKPARADATRNREA---
Mvan_1492|M.vanbaalenii_PYR-1 -----------------------------MTPPDRPVRADAARNRAL---
MAV_2463|M.avium_104 ----------------------------MTAVEDRPLRSDAARNVER---
TH_4110|M.thermoresistible__bu ----------------------------VTATDAAATGRAAARGRPRDPA
MMAR_2833|M.marinum_M ------------------------------------------METER---
MUL_3399|M.ulcerans_Agy99 MLQYLNGLWSDLFQPSYSAGVSGVEGLGELPVSARQERGDAARNREL---
Mb0068c|M.bovis_AF2122/97 ----VLEVAYQTFAADGL-SVPVDEIARRAGVGAGTVYRHFPTKEALFQA
Rv0067c|M.tuberculosis_H37Rv ----VLEVAYQTFAADGL-SVPVDEIARRAGVGAGTVYRHFPTKEALFQA
MLBr_00316|M.leprae_Br4923 ----ILGVAYEAFATEGL-SVPIDEIARRAGVGAGTVYRHFPTKEALCAA
MAB_0647|M.abscessus_ATCC_1997 ----VLEVAYQTFAEEGL-GVPIDEIARRAGVGAGTVYRHFPAKEDLYRA
Mflv_0142|M.gilvum_PYR-GCK ----VLEVAYDTFAAEGL-TVPIDEIARRAGVGAGTVYRHFPTKEALVVA
MSMEG_3807|M.smegmatis_MC2_155 ----LLAAAEEEFAERGL-AASVADIARRAGVAKGTVFRHFPTKEDLIAA
Mvan_1492|M.vanbaalenii_PYR-1 ----LLAAAEEEFAERGP-SASVADIARRAGVAKGTVFRHFPTKEDLIAA
MAV_2463|M.avium_104 ----ILRAAREVYAELGP-DAPVEAVARRAGVGERTLYRRFPAKADLVRA
TH_4110|M.thermoresistible__bu LDSAILDAALEIFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVAD
MMAR_2833|M.marinum_M ----LLRAAADHLSTRPN--ATLDEIGAAAGVSHSTLYRHFDGRTALLEA
MUL_3399|M.ulcerans_Agy99 ----LLQAARRLVAKRGAEAVTTDDIAAEAGVGKGTLFRRFGSRAGLMMV
:* .* . :. ***. *::*:: : *
Mb0068c|M.bovis_AF2122/97 VIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEAL
Rv0067c|M.tuberculosis_H37Rv VIADRMHRIIDKGHALLKSKHPGDALFAFLRSMVLQWGAT--DRGLVEAL
MLBr_00316|M.leprae_Br4923 VIGDRMPHLVDDGYVLLKSAGPGEALFTYLRSLVLHWGAT--DRGLVDAL
MAB_0647|M.abscessus_ATCC_1997 IAEDRMGSVIDKGRELLAAVDPGEALFEFLRSM-MDWGGT--DQGLVDAL
Mflv_0142|M.gilvum_PYR-GCK VAEDRVRRIAERARTLLAVEGPGQALFVFFRDM-VRSAAV--DHGLVDAL
MSMEG_3807|M.smegmatis_MC2_155 IVTAHTATLSETARSLVDAPDPGAALLEFLTEAADQRRQH--DLTFLQAA
Mvan_1492|M.vanbaalenii_PYR-1 IVSEHIAVLAAAARRLADSPDPGAALLEFLTIAADQRQRH--DLTFLQSA
MAV_2463|M.avium_104 ALDQSIAEDLTPVIDSARHAKDPLHGLTRLVEAAISLGAR--EQNLLAAA
TH_4110|M.thermoresistible__bu AIEHRVSAELAWPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAI
MMAR_2833|M.marinum_M LDHAAIEQMRDALKTSHWQEYSPIDALRILVAACEPVAGY-LTLRYVQGQ
MUL_3399|M.ulcerans_Agy99 LLDEDERASQQAFLFGPPPLGPEAAPLDRLIAFGRERICFVHAHHELLSE
. : .
Mb0068c|M.bovis_AF2122/97 AGVG-IEISSAAPEAEADFLD---LLTDLLRAAQRAGTVRPDVDVLEVKT
Rv0067c|M.tuberculosis_H37Rv AGVG-IEISSAAPEAEADFLD---LLTDLLRAAQRAGTVRPDVDVLEVKT
MLBr_00316|M.leprae_Br4923 AGAGGIDILGVAPDAEDAFLT---ILSDLLYAAQYAGTARTDVGVREVKS
MAB_0647|M.abscessus_ATCC_1997 SGAG-IDVQALIPHIEESFYA---VLGDLLRAAQQAGTVRSDVGVHEVKA
Mflv_0142|M.gilvum_PYR-GCK MNQG-LDLEAVAPGVEAAFLS---TLGDLLSAAQGAGTVRPDVDVAVVKA
MSMEG_3807|M.smegmatis_MC2_155 SADD-----SSVTAARDELHG---YVEQLVAAAREAGAIRADVTGTDVFL
Mvan_1492|M.vanbaalenii_PYR-1 SDGD-----PRVTEVRDALHA---NLETLVDRARTSGAIRADITEADVFL
MAV_2463|M.avium_104 HRAG-----SLTSDISVSLNE---ALGELVREGQRAGRIRADLVADDLPR
TH_4110|M.thermoresistible__bu YGSAVTHPALLRTYWEHYILPRRTAAIALLRRARDLGTVAADADLDVLVD
MMAR_2833|M.marinum_M SFET-----RKSVAEWREINS---EIEEIFLRGQRAGEFRTDVTADWLTE
MUL_3399|M.ulcerans_Agy99 ANRN----PLTRYGAAASVHRR--HVRVLLESADTTG--DLDVQTDALLA
. :. . * * :
Mb0068c|M.bovis_AF2122/97 LLVG--------CQAMQSYNAELAAKVTDVALDGLRANRK----------
Rv0067c|M.tuberculosis_H37Rv LLVG--------CQAMQSYNAELAAKVTDVALDGLRANRK----------
MLBr_00316|M.leprae_Br4923 ILVG--------CQAMEAYNSALAERVTDVVVDGLRAAR-----------
MAB_0647|M.abscessus_ATCC_1997 LLVG--------CQAMQSYNKDVSRQVTDVVFDGLRPRP-----------
Mflv_0142|M.gilvum_PYR-GCK LLVV--------CKVPQVFDSEVTERVTRVIEDGLRPLR-----------
MSMEG_3807|M.smegmatis_MC2_155 LMCTPIH----VVENLPDPSPDLWQRYLGILFDGLRPEGAHPLPQPPPRL
Mvan_1492|M.vanbaalenii_PYR-1 MMCAPIH----IVENLPAPAPLLWQRYLAIIFDGLRPDGAHPLPQPAPAA
MAV_2463|M.avium_104 LVAMLYS-----VLSTMDAGSEGWRRYVALVVDAISVDERRPLPPAAALR
TH_4110|M.thermoresistible__bu MLAG--A----VTYRVLQPEPPSARQLRCYLEVAYRQVGLLP--------
MMAR_2833|M.marinum_M AFFSLVSGAGWSVQHGRVARREFTHMITALFLDGVKAPTQGNLPPPLVGF
MUL_3399|M.ulcerans_Agy99 LLDVD------YVEHQLNDRGHTLRTLGDAWEDLARKLCGR---------
.
Mb0068c|M.bovis_AF2122/97 -----------------
Rv0067c|M.tuberculosis_H37Rv -----------------
MLBr_00316|M.leprae_Br4923 -----------------
MAB_0647|M.abscessus_ATCC_1997 -----------------
Mflv_0142|M.gilvum_PYR-GCK -----------------
MSMEG_3807|M.smegmatis_MC2_155 T----------------
Mvan_1492|M.vanbaalenii_PYR-1 P----------------
MAV_2463|M.avium_104 YASQPNSWPL-------
TH_4110|M.thermoresistible__bu -----------------
MMAR_2833|M.marinum_M VLLGLSVVRPNLPNSKS
MUL_3399|M.ulcerans_Agy99 -----------------