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VEMAYLGELRTHWQALTAATAGLSAGLALSAYTNAAMGPQFLAAFGWERSDFALTGVITLLTFVFLPVYG RLTDLFGVRRIAVVGVAGLPVCWLGYALMSGPIWQYFAINVAVIALGVTTTPAIYSRVVATRFDRARGLA LAIAISGPPLLGAVSAPVVAAVNRIFGWRAGCVAIAVMIAVIGVVALLLMPADQARPPRERRTGDYRMIA GTPVFWILLAGVLLCNLYHSVTTSQLGVMLDDSGAGDRIALLVTVFATSVIVGRFVCGVALDRLPPQAVA AVAMALPGLGCLLVASSWDGFGVLVIAVCCLGAAWGAEGDVIAYLVARRFSLSVYSTVLGILSALIGVSS ALGALILSRMLAESDSFNGFLLVAGSAAVIGGTLFLLVRPQRKASGAALQKPAKMSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0577 | - | - | 100% (407) | major facilitator superfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_4147 | - | 3e-36 | 29.70% (394) | major facilitator superfamily protein MFS_1, putative |
| M. smegmatis MC2 155 | MSMEG_5464 | - | 1e-13 | 25.41% (370) | integral membrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1288c | - | 2e-05 | 20.51% (390) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1096 | - | 2e-27 | 31.14% (395) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1258c | - | 3e-05 | 20.51% (390) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4839c | - | 1e-08 | 19.84% (373) | MFS family transporter |
| M. marinum M | MMAR_0434 | - | 8e-08 | 25.17% (298) | integral membrane protein |
| M. avium 104 | MAV_1539 | - | 8e-06 | 22.49% (409) | major facilitator family protein transporter |
| M. thermoresistible (build 8) | TH_0557 | - | 1e-165 | 71.19% (420) | major facilitator superfamily protein, putative |
| M. ulcerans Agy99 | MUL_1084 | - | 1e-07 | 25.17% (298) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3219 | - | 4e-08 | 22.63% (380) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0577|M.smegmatis_MC2_155 -------MEMAYLGELRTHWQALTAATAGLSAGLALSAYTNAAMGP----
TH_0557|M.thermoresistible__bu -----VTAAPSYLGEVRVNWRPLAAATAGLSAGLSLSAYTNAAMAP----
MAB_4839c|M.abscessus_ATCC_199 ---MSTAAVHAQPHSITGLRGVLITLCLTEITSWGVLYYAFPVLAP----
Mvan_3219|M.vanbaalenii_PYR-1 ---MAESDRADR-------RSVLLTLCLTEITSWGVLYYAFSVLSP----
MMAR_0434|M.marinum_M -----MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGALS
MUL_1084|M.ulcerans_Agy99 -----MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGALS
Mb1288c|M.bovis_AF2122/97 ------MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGS----
Rv1258c|M.tuberculosis_H37Rv ------MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGS----
Mflv_1096|M.gilvum_PYR-GCK MGGPVTRFDSAAIAEWRRYGTVPLAAGLGYSMGVIHVYSLGAFMGP----
MAV_1539|M.avium_104 --MVMPNGPVAHQAGTRGYRRMTAALCGAGLASFAAMYCTQALLPA----
:
MSMEG_0577|M.smegmatis_MC2_155 QFLAAFGWERSDFALTGVITLLTFVFLPV-YGRLTDLFGVRRIAVVGVAG
TH_0557|M.thermoresistible__bu QFLAAFDWSRSDFALTGVIALLTFVFLPV-YGRLTDLFGVRRIALIGVTG
MAB_4839c|M.abscessus_ATCC_199 RITADTGWSAPAVTAAFSAALVVAAAAGIGVGRWLDRHGPRWLMTAGSLW
Mvan_3219|M.vanbaalenii_PYR-1 AICADTGWSAPAVTAAFSAGLVISALLGIPVGRWLDRHGPRWIMTGGSVL
MMAR_0434|M.marinum_M AIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSLVC
MUL_1084|M.ulcerans_Agy99 AIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSLVC
Mb1288c|M.bovis_AF2122/97 --AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAG
Rv1258c|M.tuberculosis_H37Rv --AGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAG
Mflv_1096|M.gilvum_PYR-GCK -LQDEFGWSRAQASVGLTIVGMAAAVAALPIGLMVDRLGPRRVGIIGAGL
MAV_1539|M.avium_104 -LSAHHRIGPATAALTVSLTTGALALSIIPASVLSERYGRTRVMLISGVA
.
MSMEG_0577|M.smegmatis_MC2_155 LPVCWLGYALMSGPIWQYFAINVAVIALG-----VTTTPAIYSRVVATR-
TH_0557|M.thermoresistible__bu LPVCWIGYALMSGPIWQYFAIHVAMIALG-----TTTTPAIYSRLVAIR-
MAB_4839c|M.abscessus_ATCC_199 GPAALIGVAMAPNYGWFLAAWLMAGIAMA-----AVFYPPAFAALTRWYG
Mvan_3219|M.vanbaalenii_PYR-1 GSIALAGVAAAPDVVSFTAAWVVAGVAMS-----AVFYAPAFAALTRYFR
MMAR_0434|M.marinum_M LTISQLISALAPNFAVLAAGRALCAITHG-----LLWS--VIAPIATRLV
MUL_1084|M.ulcerans_Agy99 LTISQLISALAPNFAVLAAGRALCAITHG-----LLWS--VIAPIATRLV
Mb1288c|M.bovis_AF2122/97 VPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWS
Rv1258c|M.tuberculosis_H37Rv VPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWS
Mflv_1096|M.gilvum_PYR-GCK MAGAFALLGTATG-TMGNWILLWSVLAFA-----CFWVQTTVWTSAVASR
MAV_1539|M.avium_104 SSVIGLLLPFSPSLGVLVFGRAVQGVALAG-------IPAVAMALLAEEV
. . : .
MSMEG_0577|M.smegmatis_MC2_155 FDRARGLALAIAISGPPLLGAVSAPVVAAVNRIFGWRAGCVAIAVMIAVI
TH_0557|M.thermoresistible__bu FDRARGLALAVAISGPPLLGALGVPALDAVNQTLGWRWGCVAIAVAIAVV
MAB_4839c|M.abscessus_ATCC_199 PGAVRALMVLTLVAG--LASTVFVPLTAVLASHMDWRTTYLALAVLLTII
Mvan_3219|M.vanbaalenii_PYR-1 PDAVRALTALTLAAG--LASTVFAPLTAAISAHMDWRETYLVLAAAMAVI
MMAR_0434|M.marinum_M PPSHAGRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVV
MUL_1084|M.ulcerans_Agy99 PPSHAGRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVV
Mb1288c|M.bovis_AF2122/97 LDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAI
Rv1258c|M.tuberculosis_H37Rv LDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAI
Mflv_1096|M.gilvum_PYR-GCK FETSRGLAFAVTLSGGSLAAAVFPPLATLLIGEWGWRGALFGLGGLWGGL
MAV_1539|M.avium_104 DASSLGSAMGRYIAGTTIGGLAGRIVPSVVVQVGTWRVALLACSLITLAG
. . : :
MSMEG_0577|M.smegmatis_MC2_155 GVVALLLMP-----ADQA-------RPPR-----ERRTG-DYRMIAGTPV
TH_0557|M.thermoresistible__bu GFAALALAPRPNPAADPAPADPTGETPSRGRDDTHRRTGAAYRMIGRNPV
MAB_4839c|M.abscessus_ATCC_199 TVPAHIIGLR---------------RPWP--SLPATHLAESPTRIARSRP
Mvan_3219|M.vanbaalenii_PYR-1 TVPAHFFGLR---------------RPWP--HIEHHHLVEPPTRIARSRQ
MMAR_0434|M.marinum_M TVAARLLLP------------------EMVLSADQLQYVGPRSRHHRNRA
MUL_1084|M.ulcerans_Agy99 TVAARLLLP------------------EMVLSADQLQHVGPRSRHHRNRA
Mb1288c|M.bovis_AF2122/97 AALQLEGAGKP---------------HHTSRPQGLVSGIAEGLRFVWNLR
Rv1258c|M.tuberculosis_H37Rv AALQLEGAGKP---------------HHTSRPQGLVSGIAEGLRFVWNLR
Mflv_1096|M.gilvum_PYR-GCK VLIVVLLFFRG---AQDDKKPAPARTVIAPTAAAADLPGVTLAEGLRSAT
MAV_1539|M.avium_104 TAVFAVLVPRS--------------RFFTPKPASVRAALRNLAGHLRNPV
.
MSMEG_0577|M.smegmatis_MC2_155 FWILLAGVLLCNLYHSVTTSQLGVMLDDS--GAGDRIALLVTVFATSVIV
TH_0557|M.thermoresistible__bu FWILLAGILLCNLYHSVTTAQLGVVLGDSV-GSGNGVAVLVSIFAAAVIV
MAB_4839c|M.abscessus_ATCC_199 FISLIIAFALASCASYAVIVNLVPLMNQRG-LDGTVAATALALGGVGQVI
Mvan_3219|M.vanbaalenii_PYR-1 FVALTVAFAMAGLASYAVIVNLVPLMTAHG-ISTQAAALALGLGGAGQVL
MMAR_0434|M.marinum_M LIIVSLITMVGVTGHFVSYTYIVVIIRQVVGVRGPSLAWLLAAYGVAGVV
MUL_1084|M.ulcerans_Agy99 LIIVSLITMVGVTGHFVSYTYIVVIIRQVVGVRGPSLAWLLAAYGVAGVV
Mb1288c|M.bovis_AF2122/97 VLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLV
Rv1258c|M.tuberculosis_H37Rv VLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLV
Mflv_1096|M.gilvum_PYR-GCK FYKLLVAAGLFAFTTLGIVVHLVPILRDAG-AEPLAAAGTAALVGIFSIV
MAV_1539|M.avium_104 LAKLFAVGFVLMGGFVTVYNYLGYRLAARPFGLAPSVVGLLFLLYLVGTG
. : :
MSMEG_0577|M.smegmatis_MC2_155 GRFVCGVALDRLPPQAVAAVAMALPGLGCLLVASSWDGFGVLVIAVCCLG
TH_0557|M.thermoresistible__bu GRFACGLALDRLPSHLVAAVAMGLPGLGCLLIATPWDGFAVLVVAVCCLG
MAB_4839c|M.abscessus_ATCC_199 GRFGYPALAQCISVVPRTLLIMGVVAATTALLG-VFASAVSLIAVAVAAG
Mvan_3219|M.vanbaalenii_PYR-1 GRLGYQRMVRHLSVVPRTALIMAGVAVTTALLG-LLTSVATLITVAVVAG
MMAR_0434|M.marinum_M AVALVARPLDRRPKGTIIFCVAGLTFAFVLLTALAFGGHLAPMTALVVGT
MUL_1084|M.ulcerans_Agy99 AVALVARPLDRRPKGTIIFCVAGLTFAFVLLTALAFGGHLAPMTALVVGT
Mb1288c|M.bovis_AF2122/97 GALGYAVLAIRVPRRVTMSTAVLTLGLASMVIA-FLPPLPVIMVLCAVVG
Rv1258c|M.tuberculosis_H37Rv GALGYAVLAIRVPRRVTMSTAVLTLGLASMVIA-FLPPLPVIMVLCAVVG
Mflv_1096|M.gilvum_PYR-GCK GRLGVGLLLDRFPGRVVGACAYLVPILGCAALLIDGSSPLSQTVAAALFG
MAV_1539|M.avium_104 TSVVAGRLADRRGRPLVLGAALPIAVAGLLLTVPPSLAAIVAGVGVFTGG
MSMEG_0577|M.smegmatis_MC2_155 ---AAWGAEGDVIAYLVARRFSLSVYSTVLGILSALIGVSSALGALILSR
TH_0557|M.thermoresistible__bu ---AAWGAEGDVVAYLVARRFRLTVYSTVLSILSAAIGVSSAVGAVVLSR
MAB_4839c|M.abscessus_ATCC_199 ---MARGIMTLLQATAITERWGSTHYGHLSGLLTAPIMLTTALAPFTGAA
Mvan_3219|M.vanbaalenii_PYR-1 ---VVRGVMTLLQATAVTERWGITHYGQLSGILSAPVMLSTALGPFVGAG
MMAR_0434|M.marinum_M GAIVLWGAAATAVSPMLQS-AAMRSGADDPDGASGLYVTAFQVGIMAGSL
MUL_1084|M.ulcerans_Agy99 GAIVLWGAAVTAVSPMLQS-AAMRSGADDPDGASGLYVTAFQVGIMAGSL
Mb1288c|M.bovis_AF2122/97 ---LVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGP
Rv1258c|M.tuberculosis_H37Rv ---LVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGP
Mflv_1096|M.gilvum_PYR-GCK ---LTLGAEVDVIAYLASRYFGLRNFGGLFGGLVAALSLGTAFGPLAAGA
MAV_1539|M.avium_104 ------FFAAHTVASGWVGAVAQRDRAEASALYLFSYYLGGSVAGAFGGV
. .. .
MSMEG_0577|M.smegmatis_MC2_155 MLAESDSFNGFLLVAGSAAVIGGTLFLLVRPQRKASGAALQKPAKMSR--
TH_0557|M.thermoresistible__bu TLQASDSFNGFLVFAGVAAFLGGALFLLSGSRRGESDPPPEGPVRSGTAA
MAB_4839c|M.abscessus_ATCC_199 LAQLLHGYPAMFVALGVAGIIGAAAATATNPSQ-----------------
Mvan_3219|M.vanbaalenii_PYR-1 LATLLGGYGAMFVVLGAVALAAALLATATRVRPVDADG------------
MMAR_0434|M.marinum_M IGGLLYERSVAMMLTASAGLMGVALVGMTSARRVFEAPVAVAGATSHNQ-
MUL_1084|M.ulcerans_Agy99 IGGLLYERSVAMMLTASAGLMGVALVGMTSARRVFEAPVAVAGATSHNQ-
Mb1288c|M.bovis_AF2122/97 LTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ
Rv1258c|M.tuberculosis_H37Rv LTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ
Mflv_1096|M.gilvum_PYR-GCK TSDHFGGYTNFLILTMVLMGLSSMALASLKPPPVWTVTSPGEDARADRFP
MAV_1539|M.avium_104 LYG-VGGWSATVCFVVVLLMAGAALVALLVRDNGFRIGRRVVAGVASVK-
. .
MSMEG_0577|M.smegmatis_MC2_155 -----
TH_0557|M.thermoresistible__bu VASTG
MAB_4839c|M.abscessus_ATCC_199 -----
Mvan_3219|M.vanbaalenii_PYR-1 -----
MMAR_0434|M.marinum_M -----
MUL_1084|M.ulcerans_Agy99 -----
Mb1288c|M.bovis_AF2122/97 -----
Rv1258c|M.tuberculosis_H37Rv -----
Mflv_1096|M.gilvum_PYR-GCK QP---
MAV_1539|M.avium_104 -----