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MSAASHDVMTPPGAIGEFRRSWAALTAVTVGIAIGVGVLPTYVNGLVIPELEAEFGWSRTALSALPLIGS LIIIATAPVVGVVVDRFGVRIPAVSSLVAFAAGYFLLAYSNSSFGQYLLMFIVMYLLAAASTAVAFTRTI NERYDRARGLALGIALSGAGVVGFLVPSVVGPVIADNWRTGYRILAVVILLCAVVVAALMPRRTAKTAAA LPRHPGGRGLVLELIRQPRFWRLAIAFLTLALAVGGMLQHLFPMLRDAGVSAAAAARTASLVGVAVIIAR IVVGLLVDRFFAPRVAALVLVVSAAGYVALLAGGPAFAAFAGIGVGLASGAEVDIIGNLTSRYYAIESYG RVFGIFYATFFLGFGSSPLLVAWLRSLTSDYTLPILMSVALMLVAAALLFTAPRFPGEAPADVTNDATVL PAAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4147 | - | - | 100% (424) | major facilitator superfamily protein MFS_1, putative |
| M. smegmatis MC2 155 | MSMEG_0577 | - | 3e-36 | 29.70% (394) | major facilitator superfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_5194 | - | 4e-22 | 26.85% (406) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1766c | narK2 | 2e-09 | 26.74% (389) | nitrate/nitrite transporter NarK2 |
| M. gilvum PYR-GCK | Mflv_1096 | - | 1e-42 | 32.26% (403) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1737c | narK2 | 2e-09 | 26.74% (389) | nitrate/nitrite transporter NarK2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4839c | - | 1e-13 | 25.40% (374) | MFS family transporter |
| M. marinum M | MMAR_0690 | - | 9e-10 | 27.39% (398) | putative transport protein |
| M. avium 104 | MAV_3846 | - | 1e-09 | 25.00% (384) | sugar transporter family protein |
| M. thermoresistible (build 8) | TH_0557 | - | 2e-34 | 29.02% (417) | major facilitator superfamily protein, putative |
| M. ulcerans Agy99 | MUL_3826 | - | 3e-06 | 23.79% (412) | hypothetical protein MUL_3826 |
| M. vanbaalenii PYR-1 | Mvan_4547 | - | 2e-13 | 28.53% (382) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1766c|M.bovis_AF2122/97 -----------------------------------------MRGQAANLV
Rv1737c|M.tuberculosis_H37Rv -----------------------------------------MRGQAANLV
Mvan_4547|M.vanbaalenii_PYR-1 ------------------------------------------------MA
MAV_3846|M.avium_104 MAGRRPQAPMTGNGTRPTPKYPGGMQAWGMQTDPVATPDVGAGTRWSIMV
Mflv_1096|M.gilvum_PYR-GCK ---------------------------MGGPVTRFDSAAIAEWRRYGTVP
MSMEG_4147|M.smegmatis_MC2_155 -----------------------MSAASHDVMTPPGAIGEFRRSWAALTA
TH_0557|M.thermoresistible__bu ------------------------------VTAAPSYLGEVRVNWRPLAA
MAB_4839c|M.abscessus_ATCC_199 -----------------------------MSTAAVHAQPHSITGLRGVLI
MMAR_0690|M.marinum_M ----------------------------------------MTDSSRRVVL
MUL_3826|M.ulcerans_Agy99 -----------------MMRPRATVAAATPTTDLAAGRALITPRRRNFIF
Mb1766c|M.bovis_AF2122/97 LAT-WISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGR
Rv1737c|M.tuberculosis_H37Rv LAT-WISVVNFWAWNLIGPLSTSYARDMSLSSAEASLLVATPILVGALGR
Mvan_4547|M.vanbaalenii_PYR-1 LAT-WVSAINFWAWNMIGPLSTTYAGDMSLSSSEASILVATPILVGALGR
MAV_3846|M.avium_104 VSL-LATASSFLFINGVAFLIPSLQGARGIRLDEAGLLASMPSWGMVVTL
Mflv_1096|M.gilvum_PYR-GCK LAAGLGYSMGVIHVYSLGAFMGPLQDEFGWSRAQASVGLTIVGMAAAVAA
MSMEG_4147|M.smegmatis_MC2_155 VTVGIAIGVGVLPTYVNGLVIPELEAEFGWSRTALSALPLIGSLIIIATA
TH_0557|M.thermoresistible__bu ATAGLSAGLS-LSAYTNAAMAPQFLAAFDWSRSDFALTG-VIALLTFVFL
MAB_4839c|M.abscessus_ATCC_199 TLCLTEITSWGVLYYAFPVLAPRITADTGWSAPAVTAAFSAALVVAAAAG
MMAR_0690|M.marinum_M AAVGFTFFIDMLVYGIVVPVLPRLAKPAGLEFLGVGVVFACYGLAYFVLT
MUL_3826|M.ulcerans_Agy99 VALVLGILLSSLDQTIVAIALPTIVADLGEAG-RQSWVVTSYLLASTIAT
.
Mb1766c|M.bovis_AF2122/97 IVTGPLTDRFGGRAM-LIAVTLASILPVLAVGVAATMGSYALLVFFGLFL
Rv1737c|M.tuberculosis_H37Rv IVTGPLTDRFGGRAM-LIAVTLASILPVLAVGVAATMGSYALLVFFGLFL
Mvan_4547|M.vanbaalenii_PYR-1 IVVGPLTDRYGGRVM-FMAVTLASIVPVLAVGIAGSSGSYPLLVVFGFFL
MAV_3846|M.avium_104 VAWGYVLDRVGER----VVMTTGSALTALAAYAASSAHSMVLIAVY-LFL
Mflv_1096|M.gilvum_PYR-GCK LPIGLMVDRLGPRRVGIIGAGLMAGAFALLGTATGTMGNWILLWSVLAFA
MSMEG_4147|M.smegmatis_MC2_155 PVVGVVVDRFGVRIPAVSSLVAFAAGYFLLAYSNSSFGQYLLMFIVMYLL
TH_0557|M.thermoresistible__bu PVYGRLTDLFGVRRIALIGVTGLPVCWIGYALMSGPIWQYFAIHVAMIAL
MAB_4839c|M.abscessus_ATCC_199 IGVGRWLDRHGPRWLMTAGSLWGPAALIGVAMAP----NYGWFLAAWLMA
MMAR_0690|M.marinum_M PVAGWLIDRRGSRSVFLSGAIILMLATLAFGYASSP----VGLVTCRVLQ
MUL_3826|M.ulcerans_Agy99 ALVGKLGDMFGRKRVFQVAVLLFVAGSVSCGLTQS----MTMLVASRALQ
* * * : :
Mb1766c|M.bovis_AF2122/97 G--VAGTIFAVGIPFANNWYQPARR-GFSTGVFG---MGMVGTALSAFFT
Rv1737c|M.tuberculosis_H37Rv G--VAGTIFAVGIPFANNWYQPARR-GFSTGVFG---MGMVGTALSAFFT
Mvan_4547|M.vanbaalenii_PYR-1 G--VAGTVFAVGIPFANHWYEASRR-GFATGVFG---MGMVGTALSAFFT
MAV_3846|M.avium_104 GGMAAASCNTAGGRLVSAWFPPHQR-GLAMGIRQT--AQPLGIALGAMVI
Mflv_1096|M.gilvum_PYR-GCK CFWVQTTVWTS--AVASRFETSRGL-AFAVTLSGGSLAAAVFPPLATLLI
MSMEG_4147|M.smegmatis_MC2_155 A--AASTAVAFTRTINERYDRARGL-ALGIALSGAGVVGFLVPSVVGPVI
TH_0557|M.thermoresistible__bu G--TTTTPAIYSRLVAIRFDRARGL-ALAVAISGPPLLGALGVPALDAVN
MAB_4839c|M.abscessus_ATCC_199 GIAMAAVFYPPAFAALTRWYGPGAVRALMVLTLVAGLASTVFVPLTAVLA
MMAR_0690|M.marinum_M GGAAAATWVAGYATLVEIFPREQRGRAVGLASIGTALGALLGPALGGLAY
MUL_3826|M.ulcerans_Agy99 GVGGGAITVTAIALIGEVVPLRDRGRYQGILGAVIGIATIGGPLLGGYFT
Mb1766c|M.bovis_AF2122/97 PRFVRWFGLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNA---------
Rv1737c|M.tuberculosis_H37Rv PRFVRWFGLFTTHAIVAAALASTAVVAMVVLRDAPYFRPNA---------
Mvan_4547|M.vanbaalenii_PYR-1 PRFVKWFGLFTTHVIIAAALAVTAALCLFIMRDSPNFTPNH---------
MAV_3846|M.avium_104 PELAEHG-PQAGLRFTALACVFGAVASVIGIVDPP-RKPRA---------
Mflv_1096|M.gilvum_PYR-GCK GEWGWRGALFGLGGLWGGLVLIVVLLFFRGAQDDKKPAPAR---------
MSMEG_4147|M.smegmatis_MC2_155 ADNWRTGYRILAVVILLCAVVVAALMPRRTAKTAAALPRHP---------
TH_0557|M.thermoresistible__bu QTLGWRWGCVAIAVAIAVVGFAALALAPRPNPAADPAPADP---------
MAB_4839c|M.abscessus_ATCC_199 SHMDWRTTYLALAVLLTIITVPAHIIGLR--RPWPSLPATH---------
MMAR_0690|M.marinum_M EASGPHAPFLGAAGLSALAVAALAASLPQAAGGQASGPGMW---------
MUL_3826|M.ulcerans_Agy99 DCLGWRWAFWINLPVSAVVICVATAAIPALAATTRPVIDYAGIMFIGLSL
Mb1766c|M.bovis_AF2122/97 -----------------------------DPVLP---RLKAAAR------
Rv1737c|M.tuberculosis_H37Rv -----------------------------DPVLP---RLKAAAR------
Mvan_4547|M.vanbaalenii_PYR-1 -----------------------------DAVVP---KLKAAAR------
MAV_3846|M.avium_104 -----------------------------SASDQ---ELASPYRG-----
Mflv_1096|M.gilvum_PYR-GCK -----------------------------TVIAP---TAAAADLPGVTLA
MSMEG_4147|M.smegmatis_MC2_155 -----------------------------GGRGL---VLELIRQ------
TH_0557|M.thermoresistible__bu -----------------------------TGETPSRGRDDTHRRTGAAYR
MAB_4839c|M.abscessus_ATCC_199 -----------------------------LAESP---TRIARSR------
MMAR_0690|M.marinum_M -----------------------------SGERAFP--------------
MUL_3826|M.ulcerans_Agy99 AALTLATSLGGSVYAWGSAPIIGLFTAAGVTLAVFVWVETIAAQPILPIR
Mb1766c|M.bovis_AF2122/97 ---LPVTWEMSFLYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGF
Rv1737c|M.tuberculosis_H37Rv ---LPVTWEMSFLYAIVFGGFVAFSNYLPTYITTIYGFSTVDAGARTAGF
Mvan_4547|M.vanbaalenii_PYR-1 ---LPVTWEMSFLYAVVFGGFVAFSNYLPTYIKTIYGFSAVDAGARTAGF
MAV_3846|M.avium_104 ---SLTLWRIHAVAGLMMMPQTVTVTFMLVWLIRNLHWSVAAAGALVTLS
Mflv_1096|M.gilvum_PYR-GCK EGLRSATFYKLLVAAGLFAFTTLGIVVHLVPILRDAGAEPLAAAGTAALV
MSMEG_4147|M.smegmatis_MC2_155 -----PRFWRLAIAFLTLALAVGGMLQHLFPMLRDAGVSAAAAARTASLV
TH_0557|M.thermoresistible__bu MIGRNPVFWILLAGILLCNLYHSVTTAQLGVVLGDSVGSGNGVAVLVSIF
MAB_4839c|M.abscessus_ATCC_199 ------PFISLIIAFALASCASYAVIVNLVPLMNQRGLDGTVAATALALG
MMAR_0690|M.marinum_M ----GLAVPWLVAGLAVGLALGAVEATLPIDLVARFDASGVTVGLLFALT
MUL_3826|M.ulcerans_Agy99 LFAAPVFSVCCVLAFVVGFAMLGALIFVPTFMQYVNGVSATASGLRILPM
: . .
Mb1766c|M.bovis_AF2122/97 ALAAVLARPVGGWLSDRIAP-RHVVLASLAGTALLAFAAALQPP--PEVW
Rv1737c|M.tuberculosis_H37Rv ALAAVLARPVGGWLSDRIAP-RHVVLASLAGTALLAFAAALQPP--PEVW
Mvan_4547|M.vanbaalenii_PYR-1 ALAAVLARPVGGALADRFAP-KYVVLASFAGTAAMAFVAIFQPP--PDIW
MAV_3846|M.avium_104 QLLGALGRVAVGRWSDRLGS-RMRPVRYIAAAAVLVLLLLAWADYLNSRW
Mflv_1096|M.gilvum_PYR-GCK GIFSIVGRLGVGLLLDRFPG-RVVGACAYLVPILGCAALLIDGS--SPLS
MSMEG_4147|M.smegmatis_MC2_155 GVAVIIARIVVGLLVDRFFA-PRVAALVLVVSAAGYVALLAGGP----AF
TH_0557|M.thermoresistible__bu AAAVIVGRFACGLALDRLPS-HLVAAVAMGLPGLGCLLIATPWDG--FAV
MAB_4839c|M.abscessus_ATCC_199 GVGQVIGRFGYPALAQCISV-VPRTLLIMGVVAATTALLGVFAS---AVS
MMAR_0690|M.marinum_M TVAFIVTSQYAGRLSDAGRR-APVLAAGWVTLGVALAVMGVPSA---VGI
MUL_3826|M.ulcerans_Agy99 VIGMLITSIGSGSMVGRTGRYKIFPVLGTALMTLAFLLMSRTDESTSAAV
:
Mb1766c|M.bovis_AF2122/97 SAATFITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFP
Rv1737c|M.tuberculosis_H37Rv SAATFITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFP
Mvan_4547|M.vanbaalenii_PYR-1 SAATFITLALFLGIGTGGVFAWVARRAPAKSVGSVTGIVAAAGGLGGYFP
MAV_3846|M.avium_104 QAGLMVAISVIAVLDNGLEATAITEFAGPYWSGRALGIQNTTQRMMAAAG
Mflv_1096|M.gilvum_PYR-GCK QTVAAALFGLTLGAEVDVIAYLASRYFGLRNFGGLFGGLVAALSLGTAFG
MSMEG_4147|M.smegmatis_MC2_155 AAFAGIGVGLASGAEVDIIGNLTSRYYAIESYGRVFGIFYATFFLGFGSS
TH_0557|M.thermoresistible__bu LVVAVCCLGAAWGAEGDVVAYLVARRFRLTVYSTVLSILSAAIGVSSAVG
MAB_4839c|M.abscessus_ATCC_199 LIAVAVAAGMARGIMTLLQATAITERWGSTHYGHLSGLLTAPIMLTTALA
MMAR_0690|M.marinum_M QAAALVLLGAGLGAMIATIMPALADAMESAGGAQRPGTAAAAYNLAFSAG
MUL_3826|M.ulcerans_Agy99 QSVYLLILGSAIGMSSQVLVIIVQNTSEFEDLGVATSGVSLFRTIGGSFG
. . . :
Mb1766c|M.bovis_AF2122/97 PLVMGATYD---------------------------------PVDNDYT-
Rv1737c|M.tuberculosis_H37Rv PLVMGATYD---------------------------------PVDNDYT-
Mvan_4547|M.vanbaalenii_PYR-1 PLVMGASYD---------------------------------SIENDYT-
MAV_3846|M.avium_104 PPLFGALIS---------------------------------AAKYPPA-
Mflv_1096|M.gilvum_PYR-GCK PLAAGATSD---------------------------------HFGGYTN-
MSMEG_4147|M.smegmatis_MC2_155 PLLVAWLRS---------------------------------LTSDYTLP
TH_0557|M.thermoresistible__bu AVVLSRTLQ---------------------------------ASDSFNGF
MAB_4839c|M.abscessus_ATCC_199 PFTGAALAQ---------------------------------LLHGYPAM
MMAR_0690|M.marinum_M TVAGGPLAG---------------------------------WMADLRSF
MUL_3826|M.ulcerans_Agy99 AAIFGSLFVNFLNSRLASALTATEVASSPEALHRQSPAVAAPIVHAYAGS
. .
Mb1766c|M.bovis_AF2122/97 VGLLLLVATALVACTYTAL--HAREPVSEEASR-----------------
Rv1737c|M.tuberculosis_H37Rv VGLLLLVATALVACTYTAL--HAREPVSEEASR-----------------
Mvan_4547|M.vanbaalenii_PYR-1 IGLTLLVATALLAFLYTALRLHAREPQQKEAAT-----------------
MAV_3846|M.avium_104 WLLCALFPLAAMPLVPTRLLPPGLETRARRQSVRRLRWWRAVRSHALPDI
Mflv_1096|M.gilvum_PYR-GCK FLILTMVLMGLSSMALASLKPPPVWTVTSPGEDARADRFPQP--------
MSMEG_4147|M.smegmatis_MC2_155 ILMSVALMLVAAALLFTAPRFPGEAPADVTNDATVLPAAP----------
TH_0557|M.thermoresistible__bu LVFAGVAAFLGGALFLLSGSRRGESDPPPEGPVRSGTAAVASTG------
MAB_4839c|M.abscessus_ATCC_199 FVALGVAGIIGAAAATATNPSQ----------------------------
MMAR_0690|M.marinum_M QDAAMLIAVVTLTCGVLAALVHAAVVRRAVSDA-----------------
MUL_3826|M.ulcerans_Agy99 LAQVFLCAAPVAAIGFVLALFMREVPLRDIHNRDHDARVPSGDGSGQQNK
.
Mb1766c|M.bovis_AF2122/97 ------------------------------
Rv1737c|M.tuberculosis_H37Rv ------------------------------
Mvan_4547|M.vanbaalenii_PYR-1 ------------------------------
MAV_3846|M.avium_104 VRRPGQPG----------------------
Mflv_1096|M.gilvum_PYR-GCK ------------------------------
MSMEG_4147|M.smegmatis_MC2_155 ------------------------------
TH_0557|M.thermoresistible__bu ------------------------------
MAB_4839c|M.abscessus_ATCC_199 ------------------------------
MMAR_0690|M.marinum_M ------------------------------
MUL_3826|M.ulcerans_Agy99 LEGDLDTGQSVGAPGKEPDFGVDPAMGPVR