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M. marinum M MMAR_0434 (-)

annotation: integral membrane protein
coordinates: 504961 - 506217
length: 418

MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGALSAIARNLHISVVLVGTLLSWYALVAA
LTTVPLVRWTAHWPRRHALMVSLVCLTISQLISALAPNFAVLAAGRALCAITHGLLWSVIAPIATRLVPP
SHAGRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVVTVAARLLLPEMVLSADQLQYVG
PRSRHHRNRALIIVSLITMVGVTGHFVSYTYIVVIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPLD
RRPKGTIIFCVAGLTFAFVLLTALAFGGHLAPMTALVVGTGAIVLWGAAATAVSPMLQSAAMRSGADDPD
GASGLYVTAFQVGIMAGSLIGGLLYERSVAMMLTASAGLMGVALVGMTSARRVFEAPVAVAGATSHNQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0434--100% (418)integral membrane protein
M. marinum MMMAR_0577-4e-4132.89% (374) integral membrane transport protein
M. marinum MMMAR_2966-6e-0828.66% (157) integral membrane drug efflux protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0197-0.080.58% (412) integral membrane protein
M. gilvum PYR-GCKMflv_1840-1e-3028.12% (384) major facilitator transporter
M. tuberculosis H37RvRv0191-0.080.58% (412) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1429-6e-3026.85% (406) major facilitator superfamily permease
M. avium 104MAV_4987-1e-17979.55% (401) sugar transporter family protein
M. smegmatis MC2 155MSMEG_0232-1e-12759.64% (394) sugar transporter family protein
M. thermoresistible (build 8)TH_3988-9e-3031.16% (276) PUTATIVE putative MFS permease
M. ulcerans Agy99MUL_1084-0.099.52% (418) integral membrane protein
M. vanbaalenii PYR-1Mvan_4890-2e-3028.39% (384) major facilitator superfamily transporter

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0434|M.marinum_M               -------MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGA
MUL_1084|M.ulcerans_Agy99           -------MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAEILPVGA
Mb0197|M.bovis_AF2122/97            -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
Rv0191|M.tuberculosis_H37Rv         -------MTAPTGTSATTTRPWTPRIATQLSVLACAAFIYVTAEILPVGA
MAV_4987|M.avium_104                -------MTAET--ANAAARTWTPRIAAQLAILAAAAFTYVTAEILPVGA
MSMEG_0232|M.smegmatis_MC2_155      -------MTVTP----PTVSPWTVRVAAQLTVLAAAAFIYVTAEILPVGA
Mflv_1840|M.gilvum_PYR-GCK          ---MSAAVDQQSTPGASVAAPDPVVRRLAVLALALGGFGIGTTEFVAMGL
Mvan_4890|M.vanbaalenii_PYR-1       ---MTDTLHRPSGP-VSVAAPDPVVRRLAVVALALGGFGIGTTEFVAMGL
MAB_1429|M.abscessus_ATCC_1997      ---MTAVVDSRVQP---AAPVSPRVRRGAILALALGGFGIGTTEFVAMGL
TH_3988|M.thermoresistible__bu      MSESKASQDASAPAADPVDATARRTPWIAILAAALGIFVMITIEELPIGV
                                                     .           :   * . *   * * :.:* 

MMAR_0434|M.marinum_M               LSAIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSL
MUL_1084|M.ulcerans_Agy99           LSAIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRHALMVSL
Mb0197|M.bovis_AF2122/97            LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
Rv0191|M.tuberculosis_H37Rv         LSAIARNLRVSVVLVGTLLSWYALVAAVTTVPLVRWTAHWPRRRALVVSL
MAV_4987|M.avium_104                LPAIARNLQVSLVLVGTLLSWYALVAALTTIPLVRWTAHLPRRRVLVASL
MSMEG_0232|M.smegmatis_MC2_155      LPVIAADLNVSEGLVGTLMAGYALIAALTTVALVRLTARWPRRRALLVTM
Mflv_1840|M.gilvum_PYR-GCK          LPDIARSFDVSEPVAGHVISAYALGVVVGAPLIAAITARMARRTLLLALM
Mvan_4890|M.vanbaalenii_PYR-1       LPDIATGMGVSEPTAGHVISAYALGVVVGAPVIAAVTARMARRKLLLALM
MAB_1429|M.abscessus_ATCC_1997      LPNIAHGLHVTEPQAGHVISAYALGVVVGAPVIAALTARASRRTLLVALM
TH_3988|M.thermoresistible__bu      LTLIGDDLGLSSGVVGLTVTIPGVLAGAVAVLTPTLIGRLDRRLALVSAL
                                    *. *. .: ::   .*  ::  .: .   :       .:  **  *:  :

MMAR_0434|M.marinum_M               VCLTISQLISALAPNFAVLAAGRALCAITHGLLWSVIAPIATRLVPPSHA
MUL_1084|M.ulcerans_Agy99           VCLTISQLISALAPNFAVLAAGRALCAITHGLLWSVIAPIATRLVPPSHA
Mb0197|M.bovis_AF2122/97            VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
Rv0191|M.tuberculosis_H37Rv         VCLTVSQLVSALAPNFAVLAAGRVLCAVTHGLLWAVIAPIATRLVPPSHA
MAV_4987|M.avium_104                TCLTASQLISALAPNFAVLAAGRVLCAITHGLLWSVIAPIATRLVPPSHA
MSMEG_0232|M.smegmatis_MC2_155      VCLTVSQVISAMAPNFAVLAGGRVLCALAHGLMWSVIAPIGVRLVPPSHA
Mflv_1840|M.gilvum_PYR-GCK          AVFTLGNLASMLASSYETLVGARFLAGLPHGAYFGVAALVAAHLMGPQHR
Mvan_4890|M.vanbaalenii_PYR-1       ALFTIGNLASMLAPTYETLIAARFLAGLPHGAYFGVAALVAAHLMGPQNR
MAB_1429|M.abscessus_ATCC_1997      VAFTIGNAATVFAPGYAALIASRFVAGLPHGAYFGVAALVAAHLAGPGER
TH_3988|M.thermoresistible__bu      LLVFVSAATSAIAPNLPVLLASRLFAGMAIGVFWALLAVVVARVAHPDDL
                                      .  .   : :*.   .* ..* ...:. *  :.: * : .::  * . 

MMAR_0434|M.marinum_M               GRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVVTVAAR
MUL_1084|M.ulcerans_Agy99           GRATTSIYIGTSLALVIGSPLTAALSLMWGWRLAAVCVTVAAAVVTVAAR
Mb0197|M.bovis_AF2122/97            GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
Rv0191|M.tuberculosis_H37Rv         GRATTSIYIGTSLALVVGSPLTAAMSLMWGWRLAAVCVTGAAAAVALAAR
MAV_4987|M.avium_104                GRATMSIYVGTSLALVVGSPLTAALSLMWGWRLAVVCVTVAAAVVTVAAR
MSMEG_0232|M.smegmatis_MC2_155      GRATAAVYVGTGLALVVGNPLTAALSELWGWRQAVVAVAIAAAAVTLAAR
Mflv_1840|M.gilvum_PYR-GCK          AKAVAHVLTGLTVATVLGVPVASWLGQSLGWR-AAFGLVVAVGVLTLTAL
Mvan_4890|M.vanbaalenii_PYR-1       AKAVAHVLTGLTVATVLGVPIASWLGQSLGWR-AAFGLVVGVGLVTLTAL
MAB_1429|M.abscessus_ATCC_1997      AKAVGQTMLGLSVANVVGVPVATWLGNTVGWR-SAFAVVAVIGAITIAAL
TH_3988|M.thermoresistible__bu      PKALTLAFGGVSVAVVLGVPFAAWIGAMVGWRWAFVLVGALGLMVAVALT
                                     :*      *  :* *:* *.:: :.   *** : . :      ::::  

MMAR_0434|M.marinum_M               LLLPEMVLSADQLQYVGPRSRHHRNRALIIVSLITMVGVTGHFVSYTYIV
MUL_1084|M.ulcerans_Agy99           LLLPEMVLSADQLQHVGPRSRHHRNRALIIVSLITMVGVTGHFVSYTYIV
Mb0197|M.bovis_AF2122/97            LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
Rv0191|M.tuberculosis_H37Rv         LALPEMVLRADQLEHVGRRARHHRNPRLVKVSVLTMIAVTGHFVSYTYIV
MAV_4987|M.avium_104                LMLPEMVLTEHQLAHVGPRSRHHRNGRLITVSLLAMVAVTGHFVSYTFIV
MSMEG_0232|M.smegmatis_MC2_155      VLLPLMPAERARAGSAG-RPVHGRG--LLTLSLLTLIGVTGHFVAYTFIV
Mflv_1840|M.gilvum_PYR-GCK          ALWLPVQLRLMRSTSPLTELGALRRPQVWLALAVGMIGFGGMFAVYTYIA
Mvan_4890|M.vanbaalenii_PYR-1       WCWLPFQLKFMRATSPLTELGALRRPQVWLALLVGMIGFGGMFAVYTYIT
MAB_1429|M.abscessus_ATCC_1997      LRYLP-GLTDMRITNPLTELGALRRVQVWFTLLIGIVGFGGMFAFYTYIS
TH_3988|M.thermoresistible__bu      VLLPPVPVAER--TTLGQLGAAWSIPAARTGVLVTLVMVTAHFTAYTYAS
                                                                     : :: . . *. **:  

MMAR_0434|M.marinum_M               VIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPLDRRPKGTIIFCVAG
MUL_1084|M.ulcerans_Agy99           VIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPLDRRPKGTIIFCVAG
Mb0197|M.bovis_AF2122/97            VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
Rv0191|M.tuberculosis_H37Rv         VIIRDVVGVRGPNLAWLLAAYGVAGLVSVPLVARPLDRWPKGAVIVGMTG
MAV_4987|M.avium_104                EIIRNVVGVRGPTLAWVLAAYGLAGLLSVPLVARPLDHRPKSAVILCMTG
MSMEG_0232|M.smegmatis_MC2_155      AIIRDVVGIDGPHLAWLLAGYGVAGLAAMAAMARPLDLWPKASVTAALVV
Mflv_1840|M.gilvum_PYR-GCK          TTMTDVAGMPRALVPVALMVFGLGMFFGNLVGGRLADRSVVRALYLSMGA
Mvan_4890|M.vanbaalenii_PYR-1       TTMTDVAGMPRGLVPLALMMFGLGMVLGNLVGGRLADGSVVRALYLSLGA
MAB_1429|M.abscessus_ATCC_1997      TTLTSVSGLPRALVPLALSLYGIGMVTGNVLGGWMADRSVVRAIAVGLVL
TH_3988|M.thermoresistible__bu      PVLQDRIHITESGVGPMLFVFGIAGFLGNFAAGPLLRRSMRATYVVLPIG
                                      : .   :    :   *  :*:. . .    .         :       

MMAR_0434|M.marinum_M               LTFAFVLLTALAFGGHLAPMT--ALVVGTGAIVLWGAAATAVSPMLQSAA
MUL_1084|M.ulcerans_Agy99           LTFAFVLLTALAFGGHLAPMT--ALVVGTGAIVLWGAAVTAVSPMLQSAA
Mb0197|M.bovis_AF2122/97            LTAAFTLLTALAFGERHTAAT--ALLG-TGAIVLWGALATAVSPMLQSAA
Rv0191|M.tuberculosis_H37Rv         LTAAFTLLTALAFGERHTAAT--ALLG-TGAIVLWGALATAVSPMLQSAA
MAV_4987|M.avium_104                LTAAFAVLTALAFGGPTGATT--ALIG-TAAIVLWGAMATAVSPMMQSAA
MSMEG_0232|M.smegmatis_MC2_155      LAASLVTLAVLSAQPRAGVTTGAVMVIGTVAIVLWGASSTALPPMLQTSA
Mflv_1840|M.gilvum_PYR-GCK          LCAMLTLFVAASHNPWTALLA----------LFGIGLTGSAVGPALQTRL
Mvan_4890|M.vanbaalenii_PYR-1       LCGALALFVVASHNPWTALLV----------LFLIGLTGSAVGPALQTRL
MAB_1429|M.abscessus_ATCC_1997      VAAMLLIFAAVSRNPWAALAL----------VFAVGVSGTSLVPALQTRL
TH_3988|M.thermoresistible__bu      VMVGVXXXGPNSRWRPDGTRM-----------------------------
                                    :   .      :                                      

MMAR_0434|M.marinum_M               MRSGADDPDGASGLYVTAFQVGIMAGSLIGGLLYERS-VAMMLTASAGLM
MUL_1084|M.ulcerans_Agy99           MRSGADDPDGASGLYVTAFQVGIMAGSLIGGLLYERS-VAMMLTASAGLM
Mb0197|M.bovis_AF2122/97            MRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERS-LAMMLTASAGLM
Rv0191|M.tuberculosis_H37Rv         MRSGGDDPDGASGLYVTAFQIGIMAGALLGGLLYERS-LAMMLTASAGLM
MAV_4987|M.avium_104                MRNGADDPDGASGLYVTAFQVGIMAGSLLGGLLYERS-VILMLSASGVLM
MSMEG_0232|M.smegmatis_MC2_155      MRTSPEDPDGASGRYVAAFQVGIMTGALVGAGVYEAVGLTAMIGTAAVLI
Mflv_1840|M.gilvum_PYR-GCK          MDVAHDAQTLAAALNHSALNIGNATGAWVGGLVIAAGYGYTAPAGAGAVL
Mvan_4890|M.vanbaalenii_PYR-1       MDVAHDAQTLAAALNHSALNIGNATGAWVGGLVIAAGLGYTAPAAAGAVL
MAB_1429|M.abscessus_ATCC_1997      MDVADDAQTLAAALNHSALNIANAGGAWLGGLVITAGYGYRAPSLVGAAL
TH_3988|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MMAR_0434|M.marinum_M               GVALVGMTSARRVFEAPVAVAGATSHNQ
MUL_1084|M.ulcerans_Agy99           GVALVGMTSARRVFEAPVAVAGATSHNQ
Mb0197|M.bovis_AF2122/97            GVALFGMTVSQHLFENPTLSPGDG----
Rv0191|M.tuberculosis_H37Rv         GVALFGMTVSQHLFENPTLSPGDG----
MAV_4987|M.avium_104                AVALVGIAANRRMLDVAPTSSRDS----
MSMEG_0232|M.smegmatis_MC2_155      TAAMCGALAVPDVFNRSRDLSTR-----
Mflv_1840|M.gilvum_PYR-GCK          ALAGLVVLTVSVVLQKR-----------
Mvan_4890|M.vanbaalenii_PYR-1       ALAGLAVLTVSVLLQKRG----------
MAB_1429|M.abscessus_ATCC_1997      AIAGLVVLGLSVLYARSRAVALPSRAG-
TH_3988|M.thermoresistible__bu      ----------------------------