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VRTRSPAPLVGLCVFEFLSWGILYYTLPVIGVRITAATGWPPLVVPVVYTTSLLCAAFATPWAGRMVDRH GPRPVMTLGSLVGAGALVLAGVTGWLPLFAVAWLVVGVAQAGTLYPPAFAAATQWFGTVRAWPLTAITLA GGVSSTAFAPLTAALNEKLGWQTTLVVLGTGYGVVSTAAAALMLTSRWRRPVREGAEHAEYVTQIVRSAP FRRSRLALAMTALGLYAVTLNVIPLLTELGFGYHSAAIVFGLIGVGQVFGRVLYLPLRRLGTPRARTTAQ VAASTAGMGILAVVTAPLALAASAAMFAGAARGTHTLSVANAVTDRWGAESYATILGRFHRPVAIAMALG PATGSAIAAALGSYRTAAALFAVLGGLAILTARRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5464 | - | - | 100% (385) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_1169 | - | 1e-68 | 40.53% (375) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_4104 | - | 9e-22 | 25.69% (362) | transporter, major facilitator family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1766c | narK2 | 3e-08 | 24.64% (349) | nitrate/nitrite transporter NarK2 |
| M. gilvum PYR-GCK | Mflv_1096 | - | 3e-18 | 25.27% (376) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1737c | narK2 | 3e-08 | 24.64% (349) | nitrate/nitrite transporter NarK2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4839c | - | 1e-66 | 39.74% (380) | MFS family transporter |
| M. marinum M | MMAR_3825 | - | 1e-10 | 26.91% (275) | drug-transport integral membrane protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2968 | - | 3e-08 | 26.60% (421) | PUTATIVE putative major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0338 | - | 4e-08 | 23.29% (322) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_3219 | - | 3e-65 | 39.79% (377) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_4839c|M.abscessus_ATCC_199 ------MSTAAVHAQPHSITGL---RGVLITLCLTEITSWGVLYYAFPVL
Mvan_3219|M.vanbaalenii_PYR-1 ------MAESDRADR----------RSVLLTLCLTEITSWGVLYYAFSVL
MSMEG_5464|M.smegmatis_MC2_155 ------MRTRS--------------PAPLVGLCVFEFLSWGILYYTLPVI
Mb1766c|M.bovis_AF2122/97 ------MRGQAAN------------LVLATWISVVNFWAWNLIG----PL
Rv1737c|M.tuberculosis_H37Rv ------MRGQAAN------------LVLATWISVVNFWAWNLIG----PL
Mflv_1096|M.gilvum_PYR-GCK ------MGGPVTRFDSAAIAEWRR-YGTVPLAAGLGYSMGVIHVYSLGAF
MMAR_3825|M.marinum_M MIGASLVAGRARRIARGTRRARSLNPWPALWAMLVGYFMIVLDSTVVMLA
TH_2968|M.thermoresistible__bu ------VRRDAPSGTPVRR------PFLLVTALAVVVLTVAVLQTAVVPV
MUL_0338|M.ulcerans_Agy99 ------MGFLAQFRS---------FNRPSRVLMINQFGINVGFYMLMPYL
:
MAB_4839c|M.abscessus_ATCC_199 APRITADTGWSAPAVTAAFSAALVVAAAAGIGVGRWLDRHGPRWLMTAGS
Mvan_3219|M.vanbaalenii_PYR-1 SPAICADTGWSAPAVTAAFSAGLVISALLGIPVGRWLDRHGPRWIMTGGS
MSMEG_5464|M.smegmatis_MC2_155 GVRITAATGWPPLVVPVVYTTSLLCAAFATPWAGRMVDRHGPRPVMTLGS
Mb1766c|M.bovis_AF2122/97 STSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRAMLIAVT
Rv1737c|M.tuberculosis_H37Rv STSYARDMSLSSAEASLLVATPILVGALGRIVTGPLTDRFGGRAMLIAVT
Mflv_1096|M.gilvum_PYR-GCK MGPLQDEFGWSRAQASVGLTIVGMAAAVAALPIGLMVDRLGPRRVGIIGA
MMAR_3825|M.marinum_M NPSIMADQHTSYYLVIWVTSAYLLTYAAPLLVAGRLGDRFGPKNIYVIGL
TH_2968|M.thermoresistible__bu LGIMAEQLHTSATAVSWAVTANLLAAAAATPLLGRLADLYSKRRVLLAVL
MUL_0338|M.ulcerans_Agy99 ADYLAGPLGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIVAGC
. . . * * . : :
MAB_4839c|M.abscessus_ATCC_199 LWGPAALIGVAMAP-NYGWFLAAWLMAG-IAMAAVFYPPAFAALTRWYGP
Mvan_3219|M.vanbaalenii_PYR-1 VLGSIALAGVAAAP-DVVSFTAAWVVAG-VAMSAVFYAPAFAALTRYFRP
MSMEG_5464|M.smegmatis_MC2_155 LVGAGALVLAGVTG-WLPLFAVAWLVVG-VAQAGTLYPPAFAAATQWFGT
Mb1766c|M.bovis_AF2122/97 LASILPVLAVGVAA-TMGSYALLVFFGLFLGVAGTIFAVGIPFANNWYQP
Rv1737c|M.tuberculosis_H37Rv LASILPVLAVGVAA-TMGSYALLVFFGLFLGVAGTIFAVGIPFANNWYQP
Mflv_1096|M.gilvum_PYR-GCK GLMAGAFALLGTATGTMGNWILLWSVLA-FACFWVQTTVWTSAVASRFET
MMAR_3825|M.marinum_M AVFTAASLWCGLSG-SIGMLITARAVQG--LGASLLFPQTLSIITRIFEP
TH_2968|M.thermoresistible__bu VVVLAGSVLAATTA-SLPLLITARVLQG---ASFALYPISIAILRDELPP
MUL_0338|M.ulcerans_Agy99 LIRTGGFALLVVAQ-SLPSVLIAAAATG---FAGALFNPAVRAYVAADSG
:
MAB_4839c|M.abscessus_ATCC_199 GAVRALMVLTL-----VAGLASTVFVPLT--AVLASHMDWRTTYLA----
Mvan_3219|M.vanbaalenii_PYR-1 DAVRALTALTL-----AAGLASTVFAPLT--AAISAHMDWRETYLV----
MSMEG_5464|M.smegmatis_MC2_155 VRAWPLTAITL-----AGGVSSTAFAPLT--AALNEKLGWQTTLVV----
Mb1766c|M.bovis_AF2122/97 ARRGFSTGVFG-----MGMVGTALSAFFT--PRFVRWFGLFTTHAI----
Rv1737c|M.tuberculosis_H37Rv ARRGFSTGVFG-----MGMVGTALSAFFT--PRFVRWFGLFTTHAI----
Mflv_1096|M.gilvum_PYR-GCK SRGLAFAVTLS-----GGSLAAAVFPPLA--TLLIGEWGWRGALFG----
MMAR_3825|M.marinum_M QRRGVALAIWT-----ATGGVATLVGPLAG-GVLVQALGWQWIFFINVPI
TH_2968|M.thermoresistible__bu DRLGRAMAVMSGTLGFGGGAGLVVTGLLMTDGAVYQRVFWLCTAFTLAVI
MUL_0338|M.ulcerans_Agy99 DRKLEAFATFN-----IFYQAGILLGPLVG--LALLTLDFRMTVLG----
:
MAB_4839c|M.abscessus_ATCC_199 ------------------------LAVLLTIITVPAHIIGLR-------R
Mvan_3219|M.vanbaalenii_PYR-1 ------------------------LAAAMAVITVPAHFFGLR-------R
MSMEG_5464|M.smegmatis_MC2_155 ------------------------LGTGYGVVSTAAAALMLT-------S
Mb1766c|M.bovis_AF2122/97 ------------------------VAAALASTAVVAMVVLRD-------A
Rv1737c|M.tuberculosis_H37Rv ------------------------VAAALASTAVVAMVVLRD-------A
Mflv_1096|M.gilvum_PYR-GCK ------------------------LGGLWGGLVLIVVLLFFR-------G
MMAR_3825|M.marinum_M GLAGLVLAALLLPVLPVHRPQLDLLGAALSALGVFLVLFALQEGQHAGWA
TH_2968|M.thermoresistible__bu VIAVLIVPVRHRRATG----TLDWFGAAGLALGLSLGLLAITQGSHWGWT
MUL_0338|M.ulcerans_Agy99 -------------------------ASAVFAVLTAAQLMALP-------Q
. .
MAB_4839c|M.abscessus_ATCC_199 PW--PSLPATHLAESPTRIARSRP------------FISLIIAFALASCA
Mvan_3219|M.vanbaalenii_PYR-1 PW--PHIEHHHLVEPPTRIARSRQ------------FVALTVAFAMAGLA
MSMEG_5464|M.smegmatis_MC2_155 RWRRPVREGAEHAEYVTQIVRSAP------------FRRSRLALAMTALG
Mb1766c|M.bovis_AF2122/97 PY---FRPNADPVLPRLKAAARLP------------VTWEMSFLYAIVFG
Rv1737c|M.tuberculosis_H37Rv PY---FRPNADPVLPRLKAAARLP------------VTWEMSFLYAIVFG
Mflv_1096|M.gilvum_PYR-GCK AQDDKKPAPARTVIAPTAAAADLPGVTLAEGLRSATFYKLLVAAGLFAFT
MMAR_3825|M.marinum_M PWTSMMLIGGVGVIAVFVYWQSVNRGDPLVPLKIFSDRNFSLSSIGVAAV
TH_2968|M.thermoresistible__bu SPSTLGAAAASVVILVGWWCWEQRAAHPLVSTRMLSRRPMLLTNLATIFV
MUL_0338|M.ulcerans_Agy99 HLADPDTKNESILQGWKAIVCNRS------------FLGFAAAMTGAYVL
MAB_4839c|M.abscessus_ATCC_199 SYAVIVNLVP----LMNQRGLDGTVAATALALGGVGQVIG--------RF
Mvan_3219|M.vanbaalenii_PYR-1 SYAVIVNLVP----LMTAHGISTQAAALALGLGGAGQVLG--------RL
MSMEG_5464|M.smegmatis_MC2_155 LYAVTLNVIP----LLTELGFGYHSAAIVFGLIGVGQVFG--------RV
Mb1766c|M.bovis_AF2122/97 GFVAFSNYLPTY--ITTIYGFSTVDAGARTAGFALAAVLA--------RP
Rv1737c|M.tuberculosis_H37Rv GFVAFSNYLPTY--ITTIYGFSTVDAGARTAGFALAAVLA--------RP
Mflv_1096|M.gilvum_PYR-GCK TLGIVVHLVP----ILRDAGAEPLAAAGTAALVGIFSIVG--------RL
MMAR_3825|M.marinum_M AFATTAMMVPAMFFVQSAVGLSPIRSAALIAPMVVMSGVV--------SP
TH_2968|M.thermoresistible__bu GMGLYFAFLGITLFVQVPRDQAGFGFSATVLQASVVYLLPGACTGFVVAL
MUL_0338|M.ulcerans_Agy99 SFQVYLALPIQAS--LLAPGHQSVLLAAMFAVSGLIAIAG-------QLR
. .
MAB_4839c|M.abscessus_ATCC_199 GYPALAQCISVVPRTLLIMGVVAATTALLGVFA--------SAVSLIA-V
Mvan_3219|M.vanbaalenii_PYR-1 GYQRMVRHLSVVPRTALIMAGVAVTTALLGLLT--------SVATLIT-V
MSMEG_5464|M.smegmatis_MC2_155 LYLPLRRLGTPRARTTAQVAASTAGMGILAVVT--------APLALAASA
Mb1766c|M.bovis_AF2122/97 VGGWLSDRIAPRHVVLASLAGTALLAFAAALQP--------PPEVWSAAT
Rv1737c|M.tuberculosis_H37Rv VGGWLSDRIAPRHVVLASLAGTALLAFAAALQP--------PPEVWSAAT
Mflv_1096|M.gilvum_PYR-GCK GVGLLLDRFPGRVVGACAYLVPILGCAALLIDG--------SSPLSQTVA
MMAR_3825|M.marinum_M LVGKIVDRYHPKLVVSSAFTMLAVALTWLSIEMSLS-----TPIWRLVLP
TH_2968|M.thermoresistible__bu VSGRFIDRYGARPVLMVGALAGIGGFVFIAVAH--------THTWQVIAA
MUL_0338|M.ulcerans_Agy99 ITRWVAAHWRVSRSLVVGAAILAMAFVPLAMVPNAQRFGTGAAVAALLVS
. : .
MAB_4839c|M.abscessus_ATCC_199 AVAAGMARGIMTLLQATAITERWGSTHYGHLSGLLTAPIMLTTALA----
Mvan_3219|M.vanbaalenii_PYR-1 AVVAGVVRGVMTLLQATAVTERWGITHYGQLSGILSAPVMLSTALG----
MSMEG_5464|M.smegmatis_MC2_155 AMFAGAARGTHTLSVANAVTDRWGAESYATILGRFHRPVAIAMALG----
Mb1766c|M.bovis_AF2122/97 FITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFP----
Rv1737c|M.tuberculosis_H37Rv FITLAVCLGVGTGGVFAWVARRAPAASVGSVTGIVAAAGGLGGYFP----
Mflv_1096|M.gilvum_PYR-GCK AALFGLTLGAEVDVIAYLASRYFGLRNFGGLFGGLVAALSLGTAFG----
MMAR_3825|M.marinum_M ITALGVAIPFVWAPLAAIGSRDLPAQLAGTGAGVYTAARQVGAVLGASGM
TH_2968|M.thermoresistible__bu AVLTNAYISLGYGALPALVVGEAPPGATGIATGMNAIARTIGSSVAAALV
MUL_0338|M.ulcerans_Agy99 ASLLAVASAALFPFEMRTVVVLAEDKLVATNYGFYSTIVGVGILVGN---
. * : .
MAB_4839c|M.abscessus_ATCC_199 -------------PFTG-AALAQLLHGYPAMFVALGVAGIIGAAAATATN
Mvan_3219|M.vanbaalenii_PYR-1 -------------PFVG-AGLATLLGGYGAMFVVLGAVALAAALLATATR
MSMEG_5464|M.smegmatis_MC2_155 -------------PATG-SAIAAALGSYRTAAALFAVLGGLAILTARRS-
Mb1766c|M.bovis_AF2122/97 -------------PLVMGATYDPVDNDYTVGLLLLVATALVACTYTALHA
Rv1737c|M.tuberculosis_H37Rv -------------PLVMGATYDPVDNDYTVGLLLLVATALVACTYTALHA
Mflv_1096|M.gilvum_PYR-GCK -------------PLAAGATSDHFGGYTNFLILTMVLMGLSSMALASLKP
MMAR_3825|M.marinum_M AAFMTARIAAEMPPSPGNSPALRGSDGTAVRLPGLLREPFSVAMSQSMLL
TH_2968|M.thermoresistible__bu A-----------VAVAGSTTAAPSEAGFTAIFAGGAVTALFAMLLIGLSR
MUL_0338|M.ulcerans_Agy99 ------------LAVGSLMSVAHRFGADEIVWGGLILIGLATVAGLYQLD
.
MAB_4839c|M.abscessus_ATCC_199 PSQ------------------------------
Mvan_3219|M.vanbaalenii_PYR-1 VRPVDADG-------------------------
MSMEG_5464|M.smegmatis_MC2_155 ---------------------------------
Mb1766c|M.bovis_AF2122/97 REPVSEEASR-----------------------
Rv1737c|M.tuberculosis_H37Rv REPVSEEASR-----------------------
Mflv_1096|M.gilvum_PYR-GCK PPVWTVTSPGEDARADRFPQP------------
MMAR_3825|M.marinum_M PACVALCGVAAGLFMLGFSGSTDTGHEAADQPG
TH_2968|M.thermoresistible__bu TGRPAFETVEARQESRAMNHEWG----------
MUL_0338|M.ulcerans_Agy99 RQATRAERLSRRHPPAQLCQQAA----------