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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0557 | - | - | 100% (436) | major facilitator superfamily protein, putative |
| M. thermoresistible (build 8) | TH_1753 | - | 1e-07 | 22.78% (395) | major facilitator superfamily protein MFS_1, putative |
| M. thermoresistible (build 8) | TH_1066 | - | 2e-06 | 23.13% (441) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1282 | - | 5e-05 | 28.17% (142) | drug-transport integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1096 | - | 1e-26 | 28.57% (427) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1250 | - | 5e-05 | 28.17% (142) | drug-transport integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0284c | - | 3e-07 | 24.65% (361) | major facilitator transporter |
| M. marinum M | MMAR_0434 | - | 3e-05 | 27.27% (209) | integral membrane protein |
| M. avium 104 | MAV_3974 | - | 4e-06 | 23.66% (372) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_0577 | - | 1e-165 | 71.19% (420) | major facilitator superfamily protein, putative |
| M. ulcerans Agy99 | MUL_1382 | - | 4e-05 | 22.33% (412) | MFS transporter |
| M. vanbaalenii PYR-1 | Mvan_5926 | - | 6e-07 | 27.76% (389) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0557|M.thermoresistible__bu -----------------VTAAPSYLGEVRVNWRPLAAATAGLSAGLSLSA
MSMEG_0577|M.smegmatis_MC2_155 -------------------MEMAYLGELRTHWQALTAATAGLSAGLALSA
Mb1282|M.bovis_AF2122/97 --------------MTTAIRRAAGSSYFRNPWPALWAMMVGFFM-IMLDS
Rv1250|M.tuberculosis_H37Rv --------------MTTAIRRAAGSSYFRNPWPALWAMMVGFFM-IMLDS
Mflv_1096|M.gilvum_PYR-GCK ------------MGGPVTRFDSAAIAEWRRYGTVPLAAGLGYSMGVIHVY
MAV_3974|M.avium_104 --------------------------------------------MVALGY
MAB_0284c|M.abscessus_ATCC_199 --------------------------------MTRVVLIVLCALQVTMQL
MMAR_0434|M.marinum_M -------------MTSEARTATTAARPWTPRVAAQLSVLAAAAFIYVTAE
Mvan_5926|M.vanbaalenii_PYR-1 MPQAEPTQPHAPSCRKPSDARSWSDEERRRVQRRTLVVVIASQVLGGAGL
MUL_1382|M.ulcerans_Agy99 -----------------MIHDPTASRSLFASRVTVLLAIALSAFTMRSAV
TH_0557|M.thermoresistible__bu YTNAAMAPQFLAAFDWSRSDFALTGVIALLTFVF-LPVYGRLTDLFGVRR
MSMEG_0577|M.smegmatis_MC2_155 YTNAAMGPQFLAAFGWERSDFALTGVITLLTFVF-LPVYGRLTDLFGVRR
Mb1282|M.bovis_AF2122/97 TVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKN
Rv1250|M.tuberculosis_H37Rv TVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKN
Mflv_1096|M.gilvum_PYR-GCK SLGAFMGP-LQDEFGWSRAQASVGLTIVGMAAAVAALPIGLMVDRLGPRR
MAV_3974|M.avium_104 GVISPALPTFARSFGVSIKAVTFLVTVFSLSRLCFAPISGLLTERLGERR
MAB_0284c|M.abscessus_ATCC_199 YVWIPIHDIVSASYGG--QDMTPALSAALFGYAAGFLLFGPVTDRFGRRR
MMAR_0434|M.marinum_M ILPVGALSAIARNLHISVVLVGTLLSWYALVAALTTVPLVRWTAHWPRRH
Mvan_5926|M.vanbaalenii_PYR-1 AAGVSVGALLAKEMLGTESLAGIPAALFTLGSAAAAFSIGRLTQSWGRRV
MUL_1382|M.ulcerans_Agy99 TSMAPLLARVADTMGFGGTVIGVFGMLPTAMFALAGFAAP-LSRRFGPER
. .
TH_0557|M.thermoresistible__bu IALIGVTGLPVCWIGYALMSG-PIWQYFAIHVAMIALGTTTTPAIYSRLV
MSMEG_0577|M.smegmatis_MC2_155 IAVVGVAGLPVCWLGYALMSG-PIWQYFAINVAVIALGVTTTPAIYSRVV
Mb1282|M.bovis_AF2122/97 LYLIGLGVFTVASLGCGLSSG-AGMLIAARVVQGVGAGLLT-PQTLSTIT
Rv1250|M.tuberculosis_H37Rv LYLIGLGVFTVASLGCGLSSG-AGMLIAARVVQGVGAGLLT-PQTLSTIT
Mflv_1096|M.gilvum_PYR-GCK VGIIGAGLMAGAFALLGTATG-TMGNWILLWSVLAFACFWVQTTVWTSAV
MAV_3974|M.avium_104 IYIGGLLIVAVSTAACAFSQA-YWQLMLCRVFSGVGSTMFY-VSALGLMI
MAB_0284c|M.abscessus_ATCC_199 VLLAGVAVMAVLTFLVPFAPT-PVLSGLFRVIQGFAGGAFS-PSALSYLG
MMAR_0434|M.marinum_M ALMVSLVCLTISQLISALAPN-FAVLAAGRALCAITHGLLW-SVIAPIAT
Mvan_5926|M.vanbaalenii_PYR-1 GLGIGFTAGGVGAAGVVVAAASDNAPLLFAALFIYGAGTATNLQARYAGT
MUL_1382|M.ulcerans_Agy99 LALLSVLATAAGTAGRSMASD-TSELMAFTTLALVGMGIAN--IVVPPLV
.
TH_0557|M.thermoresistible__bu AIRFDRARGLALAVAISGPPLLGALGVPALDAV-NQTLGWRWGCVAIAVA
MSMEG_0577|M.smegmatis_MC2_155 ATRFDRARGLALAIAISGPPLLGAVSAPVVAAV-NRIFGWRAGCVAIAVM
Mb1282|M.bovis_AF2122/97 RIFPAHRRGVALGAWGTVASVASLVGPLAGGAL-VDSMGWEW-IFFVNVP
Rv1250|M.tuberculosis_H37Rv RIFPAHRRGVALGAWGTVASVASLVGPLAGGAL-VDSMGWEW-IFFVNVP
Mflv_1096|M.gilvum_PYR-GCK ASRFETSRGLAFAVTLSGGSLAAAVFPPLATLL-IGEWGWRGALFGLGGL
MAV_3974|M.avium_104 HISPADARGRIAGLFTTS-FMVGAVGGPAVGGL-AAGWGLTAPFVVYGVA
MAB_0284c|M.abscessus_ATCC_199 EALPRRAATTAIGAVSTAYLMAGVLGQVMASVI-TQAWGWQWLFWLSAAG
MMAR_0434|M.marinum_M RLVPPSHAGRATTSIYIGTSLALVIGSPLTAAL-SLMWGWRLAAVCVTVA
Mvan_5926|M.vanbaalenii_PYR-1 DLADPSRRGTAISVALTATTLGAVAGPNLIAPMGQVAVALGIPALAGPFL
MUL_1382|M.ulcerans_Agy99 KKYFNDRVALMSAIYLACLQLGTIMPAVAAVPL-AESYGWRASLAIWALI
: : .
TH_0557|M.thermoresistible__bu IAVVGFAALALAPRPNPAADPAPADPTGETPSRGRDDTHRRTGAAYRMIG
MSMEG_0577|M.smegmatis_MC2_155 IAVIGVVALLLMP-----ADQA-------RPPR-----ERRTG-DYRMIA
Mb1282|M.bovis_AF2122/97 VGVIGLILAAYLIPALP-HHPHRFDWFGVGLSGAGMFLIVFGLQQGQSAN
Rv1250|M.tuberculosis_H37Rv VGVIGLILAAYLIPALP-HHPHRFDWFGVGLSGAGMFLIVFGLQQGQSAN
Mflv_1096|M.gilvum_PYR-GCK WGGLVLIVVLLFFRGAQ-DDKKPAPARTVIAPTAAAADLPGVTLAEGLRS
MAV_3974|M.avium_104 MLGVALVLFLGLRNSALAAPPPP---------------TRSTVTMREALR
MAB_0284c|M.abscessus_ATCC_199 LAVNVALLALVMHEERAGDPSTR--------------VVSGFAAQARLLA
MMAR_0434|M.marinum_M AAVVTVAARLLLPEMVLSADQLQY--------------VGPRSRHHRNRA
Mvan_5926|M.vanbaalenii_PYR-1 LAAVAYVAAGSVLIALLRPDPYLVAR-----------QIDAASAREGDDT
MUL_1382|M.ulcerans_Agy99 PAVAVLPWILVLVRRRTNGTDHAAR--------------TGKKIGPIWRS
TH_0557|M.thermoresistible__bu RNPVFWILLAG-----------------------------------ILLC
MSMEG_0577|M.smegmatis_MC2_155 GTPVFWILLAG-----------------------------------VLLC
Mb1282|M.bovis_AF2122/97 WQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLGIA
Rv1250|M.tuberculosis_H37Rv WQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIA
Mflv_1096|M.gilvum_PYR-GCK ATFYKLLVAAG-------------------------------------LF
MAV_3974|M.avium_104 VRAYQSALLSN-------------------------------------FA
MAB_0284c|M.abscessus_ATCC_199 RADIAVPLVAV------------------------------------FVL
MMAR_0434|M.marinum_M LIIVSLITMVG---------------------------------------
Mvan_5926|M.vanbaalenii_PYR-1 SVTAALRPTAG-------------------------------AYVGAVVM
MUL_1382|M.ulcerans_Agy99 PISWGLTFMFS------------------------------------MTS
TH_0557|M.thermoresistible__bu NLYHSVTTAQLGVVLGDSVGSGNGVAVLVSIFAAAVIVG---RFACGLAL
MSMEG_0577|M.smegmatis_MC2_155 NLYHSVTTSQLGVMLDDS-GAGDRIALLVTVFATSVIVG---RFVCGVAL
Mb1282|M.bovis_AF2122/97 IIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMII
Rv1250|M.tuberculosis_H37Rv IIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMII
Mflv_1096|M.gilvum_PYR-GCK AFTTLGIVVHLVPILRDAGAEPLAAAGTAALVGIFSIVG---RLGVGLLL
MAV_3974|M.avium_104 TGWSAFGLRMALVPLFVSDVMGRGIGTIGVVLAAFAGGNALAVVPSGYLS
MAB_0284c|M.abscessus_ATCC_199 MLSFVAMYTSLATELVDALHLPESMGTTIRLAG---VPGMLVAPFVGSWV
MMAR_0434|M.marinum_M --VTGHFVSYTYIVVIIRQVVGVRGPSLAWLLAAYGVAGVVAVALVARPL
Mvan_5926|M.vanbaalenii_PYR-1 IVAQVAMAAIMTMTPVHMSGHHHGLSAVGLVIGLHIAAMYLPSLVTGVLV
MUL_1382|M.ulcerans_Agy99 LITYAMFAWLPVIVTSAGGSEALGGAMVATFSGVGFLATLVTPRLCARAA
. . .
TH_0557|M.thermoresistible__bu DRLPSHLVAAVAMGLPGLGCLLIATPWDG----FAVLVVAVCCLGAAWGA
MSMEG_0577|M.smegmatis_MC2_155 DRLPPQAVAAVAMALPGLGCLLVASSWDG----FGVLVIAVCCLGAAWGA
Mb1282|M.bovis_AF2122/97 DRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTP-IWRLVLPFIALGVAGAF
Rv1250|M.tuberculosis_H37Rv DRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTP-IWRLVLPFIALGVAGAF
Mflv_1096|M.gilvum_PYR-GCK DRFPGRVVGACAYLVPILGCAALLIDGSS----PLSQTVAAALFGLTLGA
MAV_3974|M.avium_104 DRMGRRTLLIVGLVTSGAATVWLGFVASLP-----VFLVAAGVVGVVTGI
MAB_0284c|M.abscessus_ATCC_199 GRVGTETGALVGYLLAAAGLAVEALGAGS-----VPIIIAGSNIFVAG--
MMAR_0434|M.marinum_M DRRPKGTIIFCVAGLTFAFVLLTALAFGGHLAPMTALVVGTGAIVLWGAA
Mvan_5926|M.vanbaalenii_PYR-1 DRIGPHAMAVAAGITLLAAGLTAAFAPGDS---LPLLVTALVLLGLGWNF
MUL_1382|M.ulcerans_Agy99 NPFPIVAASALCFLVGFAGLLWAPL---------TAPIVWAIFLGLGPST
. .
TH_0557|M.thermoresistible__bu EGDVVAYLVARRFR--LTVYSTVLSILSAAIGVSSAVGAVVLSRTLQA--
MSMEG_0577|M.smegmatis_MC2_155 EGDVIAYLVARRFS--LSVYSTVLGILSALIGVSSALGALILSRMLAE--
Mb1282|M.bovis_AF2122/97 VWSPLTVTATRNLR--PHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRI
Rv1250|M.tuberculosis_H37Rv VWSPLTVTATRNLR--PHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRI
Mflv_1096|M.gilvum_PYR-GCK EVDVIAYLASRYFG--LRNFGGLFGGLVAALSLGTAFGPLAAGATSDH--
MAV_3974|M.avium_104 YMSPLQAAVADILGN-EARAGLPVATVQMMSDLGAIVGSMAVGWAAEQ--
MAB_0284c|M.abscessus_ATCC_199 -IAVSSTAMVTMFG---DRAAPRRGAGTALYGFTVFLGASSAPYLAHA--
MMAR_0434|M.marinum_M ATAVSPMLQSAAMRSGADDPDGASGLYVTAFQVGIMAGSLIGGLLYER--
Mvan_5926|M.vanbaalenii_PYR-1 GIISGTAFVVDATVP--ANRPRVQGSIDVLIAIAGAAGGGLSGVVMSA--
MUL_1382|M.ulcerans_Agy99 FPAAITLINLRSRTE--SGSAALSGFTQGMGYLLASPGPLIFGILYNATG
. . *
TH_0557|M.thermoresistible__bu --------------------------------SDSFNGFLVFAGVAAFLG
MSMEG_0577|M.smegmatis_MC2_155 --------------------------------SDSFNGFLLVAGSAAVIG
Mb1282|M.bovis_AF2122/97 AAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFG
Rv1250|M.tuberculosis_H37Rv AAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFG
Mflv_1096|M.gilvum_PYR-GCK --------------------------------FGGYTNFLILTMVLMGLS
MAV_3974|M.avium_104 ---------------------------------IGYGWGFFISGVVLLIA
MAB_0284c|M.abscessus_ATCC_199 -----------------------------------LGFRPLLGILVAALI
MMAR_0434|M.marinum_M ------------------------------------SVAMMLTASAGLMG
Mvan_5926|M.vanbaalenii_PYR-1 ------------------------------------GGYAALSIACGVFA
MUL_1382|M.ulcerans_Agy99 --------------------------------RWELSFGFLLVPLIALLA
. :
TH_0557|M.thermoresistible__bu --GALFLLSGS--------------------------RRGESDPPPEGPV
MSMEG_0577|M.smegmatis_MC2_155 --GTLFLLVRP--------------------------QRKASGAALQKPA
Mb1282|M.bovis_AF2122/97 IVAALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPL
Rv1250|M.tuberculosis_H37Rv IVAALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPL
Mflv_1096|M.gilvum_PYR-GCK SMALASLKPPP-------------------------VWTVTSPGEDARAD
MAV_3974|M.avium_104 AVGWVMAPETR--------------------------TATELEADLMAAS
MAB_0284c|M.abscessus_ATCC_199 GGAALVASSRR--------------------------ASGPVKPVVDIST
MMAR_0434|M.marinum_M VALVGMTSARR---------------------------VFEAPVAVAGAT
Mvan_5926|M.vanbaalenii_PYR-1 LVLLPALLWDR--------------------------KRTPAS-------
MUL_1382|M.ulcerans_Agy99 GGYHACKPRYLEDTLTP--------------------SRKSGSDAVEDVV
TH_0557|M.thermoresistible__bu RSGTAAVASTG---------------------------------------
MSMEG_0577|M.smegmatis_MC2_155 KMSR----------------------------------------------
Mb1282|M.bovis_AF2122/97 RASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPS
Rv1250|M.tuberculosis_H37Rv RASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPS
Mflv_1096|M.gilvum_PYR-GCK RFPQP---------------------------------------------
MAV_3974|M.avium_104 RTSSRCEQQL----------------------------------------
MAB_0284c|M.abscessus_ATCC_199 QSSPLP--------------------------------------------
MMAR_0434|M.marinum_M SHNQ----------------------------------------------
Mvan_5926|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1382|M.ulcerans_Agy99 EGERLQECSTSCA-------------------------------------
TH_0557|M.thermoresistible__bu --
MSMEG_0577|M.smegmatis_MC2_155 --
Mb1282|M.bovis_AF2122/97 AL
Rv1250|M.tuberculosis_H37Rv AL
Mflv_1096|M.gilvum_PYR-GCK --
MAV_3974|M.avium_104 --
MAB_0284c|M.abscessus_ATCC_199 --
MMAR_0434|M.marinum_M --
Mvan_5926|M.vanbaalenii_PYR-1 --
MUL_1382|M.ulcerans_Agy99 --