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STAAVHAQPHSITGLRGVLITLCLTEITSWGVLYYAFPVLAPRITADTGWSAPAVTAAFSAALVVAAAAG IGVGRWLDRHGPRWLMTAGSLWGPAALIGVAMAPNYGWFLAAWLMAGIAMAAVFYPPAFAALTRWYGPGA VRALMVLTLVAGLASTVFVPLTAVLASHMDWRTTYLALAVLLTIITVPAHIIGLRRPWPSLPATHLAESP TRIARSRPFISLIIAFALASCASYAVIVNLVPLMNQRGLDGTVAATALALGGVGQVIGRFGYPALAQCIS VVPRTLLIMGVVAATTALLGVFASAVSLIAVAVAAGMARGIMTLLQATAITERWGSTHYGHLSGLLTAPI MLTTALAPFTGAALAQLLHGYPAMFVALGVAGIIGAAAATATNPSQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4839c | - | - | 100% (397) | MFS family transporter |
| M. abscessus ATCC 19977 | MAB_2613 | - | 2e-09 | 27.83% (345) | putative glucose/mannose:H+ symporter GlcP |
| M. abscessus ATCC 19977 | MAB_3449c | - | 7e-09 | 24.48% (388) | putative transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0872 | - | 7e-07 | 22.58% (372) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_1096 | - | 8e-22 | 25.51% (396) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0849 | - | 8e-07 | 22.58% (372) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0577 | - | 5e-07 | 24.56% (395) | integral membrane transport protein |
| M. avium 104 | MAV_4987 | - | 6e-11 | 26.32% (342) | sugar transporter family protein |
| M. smegmatis MC2 155 | MSMEG_1169 | - | 1e-149 | 67.55% (379) | integral membrane transport protein |
| M. thermoresistible (build 8) | TH_0476 | - | 2e-09 | 23.72% (371) | major facilitator superfamily protein MFS_1 |
| M. ulcerans Agy99 | MUL_0240 | - | 4e-07 | 29.13% (127) | hypothetical protein MUL_0240 |
| M. vanbaalenii PYR-1 | Mvan_3219 | - | 1e-145 | 67.37% (377) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1169|M.smegmatis_MC2_155 -MTPPSLSAGPG----LRWVLITLCV-TEITSWGVLYYAFTVLSASISSD
Mvan_3219|M.vanbaalenii_PYR-1 -MAE---SDRAD----RRSVLLTLCL-TEITSWGVLYYAFSVLSPAICAD
MAB_4839c|M.abscessus_ATCC_199 -MSTAAVHAQPHSITGLRGVLITLCL-TEITSWGVLYYAFPVLAPRITAD
Mb0872|M.bovis_AF2122/97 -MGARAIFRGFN----RPSRVLMINQ-FGINIG--FYMLMPYLADYLAGP
Rv0849|M.tuberculosis_H37Rv -MGARAIFRGFN----RPSRVLMINQ-FGINIG--FYMLMPYLADYLAGP
Mflv_1096|M.gilvum_PYR-GCK MGGPVTRFDSAAIAEWRRYGTVPLAAGLGYSMGVIHVYSLGAFMGPLQDE
MMAR_0577|M.marinum_M --MPESVTAPPELG-IRHATPGLLALTIATCLAITTEILPVGLLPAIGHT
MAV_4987|M.avium_104 --MTAETANAAARTWTPRIAAQLAILAAAAFTYVTAEILPVGALPAIARN
TH_0476|M.thermoresistible__bu ---------------VRRFAFPLLAYAFAAVMVG--TTVPTPMYAVYAER
MUL_0240|M.ulcerans_Agy99 ----MGARVRGVVLVTGRVRELAVGLTAGFIVYLDTTVLLVAFGAISASF
MSMEG_1169|M.smegmatis_MC2_155 TGWSAPAVTGAFSAGLVTSALMGIVVGRWLDRYGPRWIMTIGSVLGVVAV
Mvan_3219|M.vanbaalenii_PYR-1 TGWSAPAVTAAFSAGLVISALLGIPVGRWLDRHGPRWIMTGGSVLGSIAL
MAB_4839c|M.abscessus_ATCC_199 TGWSAPAVTAAFSAALVVAAAAGIGVGRWLDRHGPRWLMTAGSLWGPAAL
Mb0872|M.bovis_AF2122/97 LGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGF
Rv0849|M.tuberculosis_H37Rv LGLAAWAVGLVMGVRNFSQQGMFFVGGTLADRFGYKPLIIAGCLIRTGGF
Mflv_1096|M.gilvum_PYR-GCK FGWSRAQASVGLTIVGMAAAVAALPIGLMVDRLGPRRVGIIGAGLMAGAF
MMAR_0577|M.marinum_M FGVRDAVTGLLVSLYAVLVALLAVPLTVVTARFPRKPLLLTTLLGYAVSN
MAV_4987|M.avium_104 LQVSLVLVGTLLSWYALVAALTTIPLVRWTAHLPRRRVLVASLTCLTASQ
TH_0476|M.thermoresistible__bu LGFGVLTTTVVFAGYTAGVLFALVVFGRWSDALGRRPMLLAGVGCAIVSA
MUL_0240|M.ulcerans_Agy99 PEASSSARSWVLDAYFIVFAALMVPGGRWADQFGSRNVFAIGVSTFILSS
. . : : .
MSMEG_1169|M.smegmatis_MC2_155 LAVVVAP-NYACFVAAWILAGVAMSGVFYAPAFAALTRYFAPNAVRALTV
Mvan_3219|M.vanbaalenii_PYR-1 AGVAAAP-DVVSFTAAWVVAGVAMSAVFYAPAFAALTRYFRPDAVRALTA
MAB_4839c|M.abscessus_ATCC_199 IGVAMAP-NYGWFLAAWLMAGIAMAAVFYPPAFAALTRWYGPGAVRALMV
Mb0872|M.bovis_AF2122/97 ALLVVAQ-SLPSVLIAAAATGFAG-ALFNPAVRGYLAAEAGERKIEAFAM
Rv0849|M.tuberculosis_H37Rv ALLVVAQ-SLPSVLIAAAATGFAG-ALFNPAVRGYLAAEAGERKIEAFAM
Mflv_1096|M.gilvum_PYR-GCK ALLGTATGTMGNWILLWSVLAFACFWVQTTVWTSAVASRFETSRGLAFAV
MMAR_0577|M.marinum_M TLVAIAP-TFAMVAAGRAVGGVTHALFFSLCIGYAPRLVGLADVGRALAL
MAV_4987|M.avium_104 LISALAP-NFAVLAAGRVLCAITHGLLWSVIAPIATRLVPPSHAGRATMS
TH_0476|M.thermoresistible__bu LVFLIAG-SVPQLIAARFVSGMSAGIFTGTATAAVIEAAPERRRSRAAAV
MUL_0240|M.ulcerans_Agy99 VGCAVAP-TLGALVAARAAQAVGAALMGPASLALILPYFGRGSRATAVSL
* .. . *
MSMEG_1169|M.smegmatis_MC2_155 LTLVAGLSSTVFAPLTAALGSHLSWRQTYLVLAALLA--VITIPAHLFG-
Mvan_3219|M.vanbaalenii_PYR-1 LTLAAGLASTVFAPLTAAISAHMDWRETYLVLAAAMA--VITVPAHFFG-
MAB_4839c|M.abscessus_ATCC_199 LTLVAGLASTVFVPLTAVLASHMDWRTTYLALAVLLT--IITVPAHIIG-
Mb0872|M.bovis_AF2122/97 FNVFY-QSGILLGPLVGLVLLALDFRITVLAAAGVFG--LLTVAQLVALP
Rv0849|M.tuberculosis_H37Rv FNVFY-QSGILLGPLVGLVLLALDFRITVLAAAGVFG--LLTVAQLVALP
Mflv_1096|M.gilvum_PYR-GCK TLSGGSLAAAVFPPLATLLIGEWGWRGALFGLGGLWGGLVLIVVLLFFRG
MMAR_0577|M.marinum_M VGGGVSAGIVVGVPLLTSVGTAVGWRGAFAVLAVLAAVLLLVVAKLLPPV
MAV_4987|M.avium_104 IYVGTSLALVVGSPLTAALSLMWGWRLAVVCVTVAAAVVTVAARLMLPEM
TH_0476|M.thermoresistible__bu ATVANIGGLGAGPLLAGILVQYAPWPLHLTFWVHIVLMVLAAAAIAVAPE
MUL_0240|M.ulcerans_Agy99 WGTSAALAAALGPPLGGFLADTVGWRGIFLINVPIGLAVLAGLRNVDNRG
. * : :
MSMEG_1169|M.smegmatis_MC2_155 LRRPWPPVQHHHNVEAPTRTA---------------RSAPFLALMVSFAL
Mvan_3219|M.vanbaalenii_PYR-1 LRRPWPHIEHHHLVEPPTRIA---------------RSRQFVALTVAFAM
MAB_4839c|M.abscessus_ATCC_199 LRRPWPSLPATHLAESPTRIA---------------RSRPFISLIIAFAL
Mb0872|M.bovis_AF2122/97 QHRADSEREKTSILQDWRVVV---------------RNRPFLTLAAAMTG
Rv0849|M.tuberculosis_H37Rv QHRADSEREKTSILQDWRVVV---------------RNRPFLTLAAAMTG
Mflv_1096|M.gilvum_PYR-GCK AQDDKKPAPARTVIAPTAAAADLPG----VTLAEGLRSATFYKLLVAAGL
MMAR_0577|M.marinum_M SSESAPPPAGTAKGR-----------------------RRLAAVVSSNAL
MAV_4987|M.avium_104 VLTEHQLAHVGPRSRHHRN-------------------GRLITVSLLAMV
TH_0476|M.thermoresistible__bu TSPRTGRLGVQRLSLPPQVR-------------------KVFAIASLAAF
MUL_0240|M.ulcerans_Agy99 DAVAGQLVNTSAIVLIASGVGALTAGILEGPSWGWGQRRTLLLLIAGAIL
. :
MSMEG_1169|M.smegmatis_MC2_155 AALASYAVIVNLVP----LMVQRGFSTSAAAVALG----LGGAGQVLGRL
Mvan_3219|M.vanbaalenii_PYR-1 AGLASYAVIVNLVP----LMTAHGISTQAAALALG----LGGAGQVLGRL
MAB_4839c|M.abscessus_ATCC_199 ASCASYAVIVNLVP----LMNQRGLDGTVAATALA----LGGVGQVIGRF
Mb0872|M.bovis_AF2122/97 CYALSFQIYLALPMQASILMPRNQYLLIAAMFAVSGLVAVGGQLRITRWF
Rv0849|M.tuberculosis_H37Rv CYALSFQIYLALPMQASILMPRNQYLLIAAMFAVSGLVAVGGQLRITRWF
Mflv_1096|M.gilvum_PYR-GCK FAFTTLGIVVHLVP----ILRDAGAEPLAAAGTAA----LVGIFSIVGRL
MMAR_0577|M.marinum_M TYTGQFTLYTFISA----VLLAAGARPAFIGPLLL----MCGVCSLAGLW
MAV_4987|M.avium_104 AVTGHFVSYTFIVEIIRNVVGVRGPTLAWVLAAYG----LAGLLSVP-LV
TH_0476|M.thermoresistible__bu AGFAVTGLFTAVAP--SFLAEVIGVRNHAVAGAVAAS--IFAASAVTQVL
MUL_0240|M.ulcerans_Agy99 LATAMVGVARHHRRAEPIHDFDKGRFFAANAATAIFGAGFYGLLLAVVFF
. .
MSMEG_1169|M.smegmatis_MC2_155 GYQTMARRIG----VVPRTVLIMAAVAVTTALLG----------------
Mvan_3219|M.vanbaalenii_PYR-1 GYQRMVRHLS----VVPRTALIMAGVAVTTALLG----------------
MAB_4839c|M.abscessus_ATCC_199 GYPALAQCIS----VVPRTLLIMGVVAATTALLG----------------
Mb0872|M.bovis_AF2122/97 AVRWGAERSL----VVGATILAASFIPVAVIPNGQRF-------------
Rv0849|M.tuberculosis_H37Rv AVRWGAERSL----VVGATILAASFIPVAVIPNGQRF-------------
Mflv_1096|M.gilvum_PYR-GCK GVGLLLDRFPGR--VVGACAYLVPILGCAALLID----------------
MMAR_0577|M.marinum_M YVGATLDRNP-------RQTTVIIIVVVIGALLGLGA-------------
MAV_4987|M.avium_104 ARPLDHRPKSAV--ILCMTGLTAAFAVLTALAFGGPT-------------
TH_0476|M.thermoresistible__bu GASVSPRRAV----AVGCALLIVGMVFLAAALVW----------------
MUL_0240|M.ulcerans_Agy99 LTSHWHYSTFEAGLAMMPIFVAAALAAIPAGRIADARGHRWAVIPGCWVF
MSMEG_1169|M.smegmatis_MC2_155 -------------VFTTLAALVAASIVAGMARGIMTLLQATAVTDRWGTT
Mvan_3219|M.vanbaalenii_PYR-1 -------------LLTSVATLITVAVVAGVVRGVMTLLQATAVTERWGIT
MAB_4839c|M.abscessus_ATCC_199 -------------VFASAVSLIAVAVAAGMARGIMTLLQATAITERWGST
Mb0872|M.bovis_AF2122/97 ------------GVAVAVMALVLSASLLAVASAALFPFEMRAVVALSGDR
Rv0849|M.tuberculosis_H37Rv ------------GVAVAVMALVLSASLLAVASAALFPFEMRAVVALSGDR
Mflv_1096|M.gilvum_PYR-GCK --------------GSSPLSQTVAAALFGLTLGAEVDVIAYLASRYFGLR
MMAR_0577|M.marinum_M ------------SFPALLPVVLAAAVWNGAFGGIPSIYQAGAVRAQAATP
MAV_4987|M.avium_104 ------------GATTALIGTAAIVLWGAMATAVSPMMQSAAMRN--GAD
TH_0476|M.thermoresistible__bu ---------------SSLPALIATAVVAGAGQGLSFSRGLAAVSARTPSD
MUL_0240|M.ulcerans_Agy99 ALGVFLFWLLTTSRADYASRWLPGSILCGIGIRCVMPVLASAAIDAMPGQ
.
MSMEG_1169|M.smegmatis_MC2_155 HYGHLSGMLMAPIMITTALGPFVGAALASLLDGYDAMFL--------VLG
Mvan_3219|M.vanbaalenii_PYR-1 HYGQLSGILSAPVMLSTALGPFVGAGLATLLGGYGAMFV--------VLG
MAB_4839c|M.abscessus_ATCC_199 HYGHLSGLLTAPIMLTTALAPFTGAALAQLLHGYPAMFV--------ALG
Mb0872|M.bovis_AF2122/97 LVATHYGFYSTIVGVGVLVGNLAIGSLMSAARRLNTDEI--------VWG
Rv0849|M.tuberculosis_H37Rv LVATHYGFYSTIVGVGVLVGNLAIGSLMSAARRLNTDEI--------VWG
Mflv_1096|M.gilvum_PYR-GCK NFGGLFGGLVAALSLGTAFGPLAAGATSDHFGGYTNFLI--------LTM
MMAR_0577|M.marinum_M EMAG--AWVNATANLGIAAGAAIGAGLLPTIG-LAGLPW--------VAA
MAV_4987|M.avium_104 DPDGASGLYVTAFQVGIMAGSLLGG--LLYERSVILMLS--------ASG
TH_0476|M.thermoresistible__bu QRGEVSSTYFVVAYVALLVPVIGEGWAAHHWGLRTAGIS--------FAV
MUL_0240|M.ulcerans_Agy99 LLGTANALNSMLRQFGAALGTAAVGTLLVERSGHSPIDVGSFRVVWAFLG
. . .
MSMEG_1169|M.smegmatis_MC2_155 VVAAVAAALAAATGVRPTSGSADPSAAGDRRPPCSAEH------------
Mvan_3219|M.vanbaalenii_PYR-1 AVALAAALLATATRVRPVDADG----------------------------
MAB_4839c|M.abscessus_ATCC_199 VAGIIGAAAATAT--NPSQ-------------------------------
Mb0872|M.bovis_AF2122/97 GLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR----------------
Rv0849|M.tuberculosis_H37Rv GLILVGIVAVAGLRRLDTFTSGSQNMTGRWAAPR----------------
Mflv_1096|M.gilvum_PYR-GCK VLMGLSSMALASLKPPPVWTVTSPGEDARADRFPQP--------------
MMAR_0577|M.marinum_M ALIAISLAVTLATGRGPTH-------------------------------
MAV_4987|M.avium_104 VLMAVALVGIAANRRMLDVAPTSSRDS-----------------------
TH_0476|M.thermoresistible__bu GVAVLAIGCLIAILIQESRDPQAI--------------------------
MUL_0240|M.ulcerans_Agy99 TLTIATIPFALRLIRPGVATTGRGAPTGSRRMRIATLAVSRSTFRKKHLR
MSMEG_1169|M.smegmatis_MC2_155 ----
Mvan_3219|M.vanbaalenii_PYR-1 ----
MAB_4839c|M.abscessus_ATCC_199 ----
Mb0872|M.bovis_AF2122/97 ----
Rv0849|M.tuberculosis_H37Rv ----
Mflv_1096|M.gilvum_PYR-GCK ----
MMAR_0577|M.marinum_M ----
MAV_4987|M.avium_104 ----
TH_0476|M.thermoresistible__bu ----
MUL_0240|M.ulcerans_Agy99 ANDQ