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VIRRWLCLAVVTAVACLLTACGGGSSSSGPVEIAVWHGYQDTEGEAFKGLIDQYNKEHPDVHVTDLYSSN DLVLQKVLTAVRGGSAPDVAYMFGSWSPNIAKIPQVVDMSDVVSQSDWNWDDFYPAEREAATVGDKIVGI PALVDNLAIVYNKKLFADAGIAPPTADWTWDDFRAAAAKLTDPAKGQYGWLIPADGSEDTVWHYVPMLWE AGGDILTPDNEKAAFNSEAGVTALTMLQDMAVTDKSLYLDTTNENGPKLMNSGKVGMLITGPWDLSQLSD IDYGVQVMPTFAGSSGAHQTISGPDNWVVFDNGDKRKQASIDFVKWLTAPEQVKAFSLQTGDLPTRSSVG DDQAVRDQLDQKLPGSSVFVENLNNAKKARPAVEQYPAISEALGQAIVAVMLGKEQPAAALNSAAEAADS ALAGK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0515 | - | - | 100% (425) | sugar transporter sugar binding lipoprotein |
| M. smegmatis MC2 155 | MSMEG_4468 | - | 3e-15 | 22.35% (443) | extracellular solute-binding protein UspC |
| M. smegmatis MC2 155 | MSMEG_5145 | - | 1e-14 | 21.68% (392) | extracellular solute-binding protein, family protein 1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2857c | ugpB | 6e-15 | 22.56% (390) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
| M. gilvum PYR-GCK | Mflv_3775 | - | 8e-07 | 19.91% (447) | extracellular solute-binding protein |
| M. tuberculosis H37Rv | Rv2833c | ugpB | 8e-15 | 22.31% (390) | sn-glycerol-3-phosphate-binding lipoprotein UGPB |
| M. leprae Br4923 | MLBr_01770 | uspC | 1e-12 | 22.80% (443) | sugar transport periplasmic binding protein |
| M. abscessus ATCC 19977 | MAB_1715c | - | 1e-12 | 24.16% (418) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_1900 | - | 4e-14 | 22.78% (360) | ABC-type sugar transport protein |
| M. avium 104 | MAV_2476 | - | 8e-11 | 23.55% (344) | sugar ABC transporter, sugar-binding protein |
| M. thermoresistible (build 8) | TH_2011 | - | 2e-11 | 28.14% (231) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 5e-12 | 22.87% (411) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | Mvan_2624 | - | 1e-06 | 21.90% (379) | extracellular solute-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2857c|M.bovis_AF2122/97 -------------MDPLNRRQFLALA-AAAAGVTAGCAGMGGGGSVKS-G
Rv2833c|M.tuberculosis_H37Rv -------------MDPLNRRQFLALA-AAAAGVTAGCAGMGGGGSVKS-G
MMAR_1900|M.marinum_M -------------MNSMHRRRFLSLASAAAAGVTAGCAGITNNVSIKS-G
MLBr_01770|M.leprae_Br4923 -------------MTRPRYSTLVAEALALATVLLTATAMLMGWSGGQLRG
MUL_1246|M.ulcerans_Agy99 -------------MNRPRFSTLVAVAVTLIAALLGVTAVALDRIDAPP-G
MAB_1715c|M.abscessus_ATCC_199 ----------------MKASTRAALTLALVALLLFGVAAWLGIPTTPH--
Mflv_3775|M.gilvum_PYR-GCK MRFAQIPT-ARRGGK--TARSAVLALLAVLALVLSACAGSGGPEQAESTG
Mvan_2624|M.vanbaalenii_PYR-1 MRITQWPTSGRRSGRPGTAFSAVMALVAVLALVLTGCAGSGGPEQAEATG
TH_2011|M.thermoresistible__bu -----------------VRRTPIRAVLAAVAAVCLTLTGCAGAGTLGSSG
MAV_2476|M.avium_104 ----------------MLDRPFGRRSLLRGAGALSAAALAPWSAGCGSDD
MSMEG_0515|M.smegmatis_MC2_155 ----------------MIRRWLCLAVVTAVACLLTACGG-----GSSSSG
:
Mb2857c|M.bovis_AF2122/97 SGPIDFWSSHPG-------QSSAAERELIGRFQDRFPTLSVKLIDAGKDY
Rv2833c|M.tuberculosis_H37Rv SGPIDFWSSHPG-------QSSAAERELIGRFQDRFPTLSVKLIDAGKDY
MMAR_1900|M.marinum_M PGPISFWSNHPG-------QSSGVEKVLIDRFQQQFPGLSVKLVDAGMDY
MLBr_01770|M.leprae_Br4923 GKVVVTMRLWAD-------QISTAYSQSFQAFTRTHP--DIEVHTNVVAY
MUL_1246|M.ulcerans_Agy99 GKIVVTVRLWAA-------PIAAAYQQSFAAFSRTHP--NIEVHTNLVSF
MAB_1715c|M.abscessus_ATCC_199 GKTVVTVRVWDQ-------QVAEAYRGSFDEFSRRNP--DIQVAVTVTSY
Mflv_3775|M.gilvum_PYR-GCK SGEVSADTSGTVRILMENVPDTDIVKSMVADFNAEYP--GVEINIESLTF
Mvan_2624|M.vanbaalenii_PYR-1 TGEVSTDVSGTVRILMENVPDTDIVKSMVADFNKEYP--GVEINIESLTF
TH_2011|M.thermoresistible__bu NTVTIALVSNSQ---------MSDAQRLAPHFEAANP--DIRLKFVTLSE
MAV_2476|M.avium_104 DGALTFFFAANP-------EERDARMRIIDEFARRHP--DIKVRAVLSG-
MSMEG_0515|M.smegmatis_MC2_155 PVEIAVWHGYQD-------TEGEAFKGLIDQYNKEHP--DVHVTDLYSSN
: * .:.:
Mb2857c|M.bovis_AF2122/97 DEVAQKFNAALIG-TDVPDVVLLDDRWWFHFALIGVLTALDDLFGQV---
Rv2833c|M.tuberculosis_H37Rv DEVAQKFNAALIG-TDVPDVVLLDDRWWFHFALSGVLTALDDLFGQV---
MMAR_1900|M.marinum_M DEVAEKFNAALIG-DDVPDVVVLDDIWWFHFALSGVISPLDKLFRQI---
MLBr_01770|M.leprae_Br4923 SKYFNTLRTDVAG-GSADDIFWLSSAYLAAYADNGRLINISNSLGQR---
MUL_1246|M.ulcerans_Agy99 STYFDTLRTDVAG-GSADDIFWLSNAYLAAYADSGRLMKIDTAVDP----
MAB_1715c|M.abscessus_ATCC_199 ASYFNSLRTDVAG-HGADDIFWLSNAYLSDYADTGNLVPVEP--------
Mflv_3775|M.gilvum_PYR-GCK DQMRDKLVSSFQSSSPAYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
Mvan_2624|M.vanbaalenii_PYR-1 DQMRDKLVSSFQSSSPTYDLIVVDNPWMVDFANAKFLQPLDARIDSTP--
TH_2011|M.thermoresistible__bu NQARAKITASTAMGGGEFDVVMISNYETPQWAADGWLVNLSDYARQTP--
MAV_2476|M.avium_104 PGVMQQLSTFCVG-GRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAF
MSMEG_0515|M.smegmatis_MC2_155 DLVLQKVLTAVRG-GSAPDVAYMFGSWSPNIAKIPQVVDMSDVVSQSD--
. : *: * : :
Mb2857c|M.bovis_AF2122/97 -GVDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLP--
Rv2833c|M.tuberculosis_H37Rv -GVDTTDYVDSLLADYEFNGRHYAVPYARST-PLFYYNKAAWQQAGLP--
MMAR_1900|M.marinum_M -GVDTSDYVDTLLADYEFNGRHYALPYARST-PLFYYNKAVWQRAGLP--
MLBr_01770|M.leprae_Br4923 ---ATSDWEPAVVDQFTRAGALWGVPQLTDAGIAVFYNADLLTAAGIDPV
MUL_1246|M.ulcerans_Agy99 -----GEWEPAVVDQFTRNGVLWGVPQLTDAGIAVFYNADLLAAAGVDPA
MAB_1715c|M.abscessus_ATCC_199 ----RADWDPSVVAQFTRDGKLWGVPQLSDAGIALYYNKNLLDAAQVDPA
Mflv_3775|M.gilvum_PYR-GCK -DYDAGDFFTPLTDITTVDGTRYGVPFYNYALGYLYNADDLAAANQQVPT
Mvan_2624|M.vanbaalenii_PYR-1 -DYDAADFFKPLTDITTVDGARYGVPFYNYALGYLYNADDLTAANQQVPT
TH_2011|M.thermoresistible__bu -GYDEDDFIPSIRESLSYEGDMYAVPFYGES-SFLMYRKDLFEKSGIDMP
MAV_2476|M.avium_104 AQQLQADSIPALYETFTFNGKQYALPEQWSG-NYLFYNKRLFDEAGVPSP
MSMEG_0515|M.smegmatis_MC2_155 --WNWDDFYPAEREAATVGDKIVGIPALVDN-LAIVYNKKLFADAGIAPP
: . . .:* .
Mb2857c|M.bovis_AF2122/97 DRGLQSWS---EFDEWGPELQRVVGAGR--------------SAHGWANA
Rv2833c|M.tuberculosis_H37Rv DRGPQSWS---EFDEWGPELQRVVGAGR--------------SAHGWANA
MMAR_1900|M.marinum_M DRGPNSWQ---EFDDWGPRLQRVVDERQ--------------WAHGWANA
MLBr_01770|M.leprae_Br4923 QLNRMQWTSNDD-DTLRPLLTQLTLDTNGHVAKTPGFDSRRVRQWGYNAA
MUL_1246|M.ulcerans_Agy99 ELDGLRWSPGPD-DTLRALLARLTVDADGHVGGTPGFDPGRVRQWGYNAA
MAB_1715c|M.abscessus_ATCC_199 ELAELRWDPDPEVDTLRPMLHRLTAPG----------------HWGYNAA
Mflv_3775|M.gilvum_PYR-GCK TLDELVSTS----KALKSGDRAGIAMQP---------------QRGYKIF
Mvan_2624|M.vanbaalenii_PYR-1 TLDELVSTS----KALKSGDRAGIAMQP---------------QRGYKIF
TH_2011|M.thermoresistible__bu HNPTWQQVAD-AAAALDTPDMAGICLRG---------------KPGWGEV
MAV_2476|M.avium_104 PTAWERPWDFSEFLDTARALTKRDASGR---------------AAQYGFV
MSMEG_0515|M.smegmatis_MC2_155 TADW-------TWDDFRAAAAKLTDPAKG--------------QYGWLIP
:
Mb2857c|M.bovis_AF2122/97 DLI----SWTFQGPNWAFGGAYSDK-----WTLTLTEPATIAAGNFYRNS
Rv2833c|M.tuberculosis_H37Rv DLI----SWTFQGPNWAFGGAYSDK-----WTLTLTEPATIAAGNFYRNS
MMAR_1900|M.marinum_M ELI----SWTFQGVNWTFDGSYSDL-----WTLRFTDPDTIAAGNFYRDS
MLBr_01770|M.leprae_Br4923 NDP----QAIYLNYIGSAGGVFQRG-----DEFAFDNPSAVEAFRYLVGL
MUL_1246|M.ulcerans_Agy99 NDP----QAIYLNYIGSAGGVFMRD-----NEFAFDNPPAIDAFRYLVGL
MAB_1715c|M.abscessus_ATCC_199 NDL----QGIYLNYLGSAGAVFQAD-----DKFAFAKPRAEMAFTYLVDL
Mflv_3775|M.gilvum_PYR-GCK EEWG---NWLFAAG----GSIYDAD-----GKITLNTPEAKRALEAYIDT
Mvan_2624|M.vanbaalenii_PYR-1 EEWG---NWLFAAG----GSIYDAD-----GKITLNTPEAKRALEAYIDT
TH_2011|M.thermoresistible__bu LAPL---DTVINTFG---GRWYDMD-----WNAQLDSPEVEEAVSFYVNL
MAV_2476|M.avium_104 NTWG---SYYSAGLFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADL
MSMEG_0515|M.smegmatis_MC2_155 ADGSEDTVWHYVPMLWEAGGDILTP---DNEKAAFNSEAGVTALTMLQDM
. : * .
Mb2857c|M.bovis_AF2122/97 IHGKGYAAVANDIAN-------EFATGILASAVASTGSLPGITASAR-FD
Rv2833c|M.tuberculosis_H37Rv IHGKGYAAVANDIAN-------EFATGILASAVASTGSLAGITASAR-FD
MMAR_1900|M.marinum_M IHTKRYAAVANNIAN-------EFATGIMASAVASTGSLTGITQMAK-FD
MLBr_01770|M.leprae_Br4923 INNDHVAPPASETNNNGDFSRNQFLSGRMALFQSGTYNLALIAREAR-FH
MUL_1246|M.ulcerans_Agy99 INNDHVAPPASDTNDNGDFSRNQFLAGRMALFQSGTYSLAPVARDAT-FR
MAB_1715c|M.abscessus_ATCC_199 INVDRVAPSAADTNDNNDFSRNQFLQGRMALFQSGTYNLAQIQANAT-FP
Mflv_3775|M.gilvum_PYR-GCK YN---TAAPANSLSWGMDEAQRSVSANQSASMINYNWQLPALNEPGSGPA
Mvan_2624|M.vanbaalenii_PYR-1 YN---TAAPANSLSWGMDEAQRSVSANQAASMINYNWQLPALNEPGSGPA
TH_2011|M.thermoresistible__bu VRDHGEPGPATSGFG---ECATQFAQGRAAMWYDATSAVSVLEDPAQSNV
MAV_2476|M.avium_104 ANKYRVAPNASETQS--MSTPNLFAVGRAAMALGGHWRYQTYLRAEG-LD
MSMEG_0515|M.smegmatis_MC2_155 AVTDKSLYLDTTNEN----GPKLMNSGKVGMLITGPWDLSQLSDIDY--G
. . .
Mb2857c|M.bovis_AF2122/97 FGAAPLPTGPDAAPACPTGGAG--LAIPAKLSEERKVNALKFIAFVTNPT
Rv2833c|M.tuberculosis_H37Rv FGAAPLPTGPDAAPACPTGGAG--LAIPAKLSEERKVNALKFIAFVTNPT
MMAR_1900|M.marinum_M FGAAPVPTGPGGAPGCPTGGAG--LAIPTKLSDERKRNALRFIEYITNPV
MLBr_01770|M.leprae_Br4923 WGIAMMPTGPQGRVSVTNG-----IAVAGNSATKHPDAVRQVLAWMGSRE
MUL_1246|M.ulcerans_Agy99 WGVAMLPIGPAGRVSVTNG-----IAAAGNSASQHPDAVRQVLAWMGSSA
MAB_1715c|M.abscessus_ATCC_199 WDVAMMPAGPQGRVSVTNG-----IVAAANSSSPHPDAVHKVLAWMGSTD
Mflv_3775|M.gilvum_PYR-GCK AGKIKLATIPGGKQVLGSWS----WAIPANSAT--PDAAWAFVSWITAKP
Mvan_2624|M.vanbaalenii_PYR-1 AGKIKLATIPGGKQVLGSWS----WAIPANSAT--PDAAWAFVSWITAKP
TH_2011|M.thermoresistible__bu VGKVGYALAPTVVKADAGWLYT--WALGIPASSDNKDSAWKFISWMTDKN
MAV_2476|M.avium_104 FDVAPLPVGPAVGKGQPACSDIGATGLAISSSSPRKEQAWEFVKFATGPV
MSMEG_0515|M.smegmatis_MC2_155 VQVMPTFAGSSGAHQTISGPDN---WVVFDNGDKRKQASIDFVKWLTAPE
. . .: :
Mb2857c|M.bovis_AF2122/97 NTAYFSQQTGYLPV---------------RKSAVDDASERHYLADNPRAR
Rv2833c|M.tuberculosis_H37Rv NTAYFSQQTGYLPV---------------RKSAVDDASERHYLADNPRAR
MMAR_1900|M.marinum_M NTAYFSQRTGYLAV---------------RKSAADVPSEQKYLADHPRAR
MLBr_01770|M.leprae_Br4923 GNAYLGRHGAAVPA---------------VRSAQSV-YFDYWAAKGIDVT
MUL_1246|M.ulcerans_Agy99 GNEYLGRDGVAIPA---------------VRSAQPS-YFAFWEAKGVNVN
MAB_1715c|M.abscessus_ATCC_199 GNSFLGRSGSAIPA---------------VLSARAP-YFQYWADKGVDVS
Mflv_3775|M.gilvum_PYR-GCK NDVVRTEKGGAAIR---------------KSTLQNPAVLQGQFG--EEYY
Mvan_2624|M.vanbaalenii_PYR-1 NDVVRTEKGGAAIR---------------QSTLQDPAVLGGQFG--EEYY
TH_2011|M.thermoresistible__bu YIRLVGEELGWARVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQH
MAV_2476|M.avium_104 GQALIGESCLFVPV---------------LRSALKSDGFARAHRRVGNLG
MSMEG_0515|M.smegmatis_MC2_155 QVKAFSLQTGDLPTR--------------SSVGDDQAVRDQLDQKLPGSS
Mb2857c|M.bovis_AF2122/97 VALDQLPHTRTQDYARVFLPGGDRIISAGLESIGLRGADVTKTFTNIQKR
Rv2833c|M.tuberculosis_H37Rv VALDQLPHTRTQDYARVFLPGGDRIISAGLESIGLRGADVTKTFTNIQKR
MMAR_1900|M.marinum_M VAINQLPHTRPQDYARVFLPGADRIISAGLESIGLRGTNVAKTFASIERQ
MLBr_01770|M.leprae_Br4923 PFFSVLDGPHIPAPGGAGFPAGDDALQSYFDEMFLGHGDVEKILCQAQAA
MUL_1246|M.ulcerans_Agy99 PFFAVLSGSRIPAPGGAGFAAGNDALKPYFDEMFLGRGQVATILREAQAA
MAB_1715c|M.abscessus_ATCC_199 PFFEVLRGQQIAAPGGQGFGAGFAALKPYFAEMFLGRLDVREALQQAQRA
Mflv_3775|M.gilvum_PYR-GCK RTVEQLLADAAPLTQGPSGEEMIQAVGTALNEAVAGEKSVDDALATAQAE
Mvan_2624|M.vanbaalenii_PYR-1 RTVEQLLANAAPLTQGPSGEEMIQAVGTELNEAVAGKKSVDDALAAAQAE
TH_2011|M.thermoresistible__bu PTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKY
MAV_2476|M.avium_104 VLTDGPAFSQG-LPITPAWEKVNALMDRNFGPILRGSRPATSLAGLSRSV
MSMEG_0515|M.smegmatis_MC2_155 VFVENLNNAKKARPAVEQYPAISEALGQAIVAVMLGKEQPAAALNSAAEA
: :
Mb2857c|M.bovis_AF2122/97 LQVILDRQIMRKLAGHG
Rv2833c|M.tuberculosis_H37Rv LQVILDRQIMRKLAGHG
MMAR_1900|M.marinum_M LQIILDRQIVRKLRQHG
MLBr_01770|M.leprae_Br4923 ANTAAHR----------
MUL_1246|M.ulcerans_Agy99 ANAAARR----------
MAB_1715c|M.abscessus_ATCC_199 ANRALER----------
Mflv_3775|M.gilvum_PYR-GCK AEKIQG-----------
Mvan_2624|M.vanbaalenii_PYR-1 AEKIQG-----------
TH_2011|M.thermoresistible__bu AQVVGKTYQEKP-----
MAV_2476|M.avium_104 DEVLRSP----------
MSMEG_0515|M.smegmatis_MC2_155 ADSALAGK---------
: