For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTRPRYSTLVAEALALATVLLTATAMLMGWSGGQLRGGKVVVTMRLWADQISTAYSQSFQAFTRTHPDIE VHTNVVAYSKYFNTLRTDVAGGSADDIFWLSSAYLAAYADNGRLINISNSLGQRATSDWEPAVVDQFTRA GALWGVPQLTDAGIAVFYNADLLTAAGIDPVQLNRMQWTSNDDDTLRPLLTQLTLDTNGHVAKTPGFDSR RVRQWGYNAANDPQAIYLNYIGSAGGVFQRGDEFAFDNPSAVEAFRYLVGLINNDHVAPPASETNNNGDF SRNQFLSGRMALFQSGTYNLALIAREARFHWGIAMMPTGPQGRVSVTNGIAVAGNSATKHPDAVRQVLAW MGSREGNAYLGRHGAAVPAVRSAQSVYFDYWAAKGIDVTPFFSVLDGPHIPAPGGAGFPAGDDALQSYFD EMFLGHGDVEKILCQAQAAANTAAHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01770 | uspC | - | 100% (446) | sugar transport periplasmic binding protein |
| M. leprae Br4923 | MLBr_01427 | - | 2e-15 | 25.81% (341) | putative ABC-transport lipoprotein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2345 | uspC | 0.0 | 74.66% (446) | periplasmic sugar-binding lipoprotein UspC |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2318 | uspC | 0.0 | 74.89% (446) | periplasmic sugar-binding lipoprotein UspC |
| M. abscessus ATCC 19977 | MAB_1715c | - | 1e-137 | 57.60% (441) | sugar ABC transporter, sugar-binding protein |
| M. marinum M | MMAR_3619 | uspC | 0.0 | 71.52% (446) | periplasmic sugar-binding lipoprotein UspC |
| M. avium 104 | MAV_2088 | - | 0.0 | 74.22% (446) | extracellular solute-binding protein |
| M. smegmatis MC2 155 | MSMEG_4468 | - | 1e-165 | 64.25% (442) | extracellular solute-binding protein UspC |
| M. thermoresistible (build 8) | TH_2011 | - | 1e-07 | 22.25% (355) | substrate binding protein |
| M. ulcerans Agy99 | MUL_1246 | uspC | 0.0 | 71.52% (446) | periplasmic sugar-binding lipoprotein UspC |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2345|M.bovis_AF2122/97 MTRPRQSTLVATALVLVAILLGVTAVLLGLSAE-PRGGKIVVTVRLWDEP
Rv2318|M.tuberculosis_H37Rv MTRPRQSTLVATALVLVAILLGVTAVLLGLSAE-PRGGKIVVTVRLWDEP
MMAR_3619|M.marinum_M MSRPRFSTLVAVAVTLIAALLGVTAVALDRIDA-PPGGKIVVTVRLWAAP
MUL_1246|M.ulcerans_Agy99 MNRPRFSTLVAVAVTLIAALLGVTAVALDRIDA-PPGGKIVVTVRLWAAP
MLBr_01770|M.leprae_Br4923 MTRPRYSTLVAEALALATVLLTATAMLMGWSGGQLRGGKVVVTMRLWADQ
MAV_2088|M.avium_104 MTRPRFSTLVAGAVALVAALLAAAAVLLDYSGQ-PHGDKTIVTVRVWGDE
MSMEG_4468|M.smegmatis_MC2_155 MRR---STLLAGGLAVTMAVLLVIAMLMGRTTE--PAGKTVVTVRLWDPQ
MAB_1715c|M.abscessus_ATCC_199 ---MKASTRAALTLALVALLLFGVAAWLGIPTT--PHGKTVVTVRVWDQQ
TH_2011|M.thermoresistible__bu ---VRRTPIRAVLAAVAAVCLTLTGCAGAGTLG---SSGNTVTIALVSNS
:. * .: * . . **: :
Mb2345|M.bovis_AF2122/97 IAAAYRQSFAAFTRSHPDIEVRTNLVAYS-TYFETLRTDVAGGSADDIFW
Rv2318|M.tuberculosis_H37Rv IAAAYRQSFAAFTRSHPDIEVRTNLVAYS-TYFETLRTDVAGGSADDIFW
MMAR_3619|M.marinum_M IAAAYQQSFAAFSRTHPNIEVHTNLVSFS-TYFDTLRTDVAGGSADDIFW
MUL_1246|M.ulcerans_Agy99 IAAAYQQSFAAFSRTHPNIEVHTNLVSFS-TYFDTLRTDVAGGSADDIFW
MLBr_01770|M.leprae_Br4923 ISTAYSQSFQAFTRTHPDIEVHTNVVAYS-KYFNTLRTDVAGGSADDIFW
MAV_2088|M.avium_104 LAEAYRQSFAAFTRAHPDIEVHVNMVAYS-TYFNTLRTDVAGGSADDIFW
MSMEG_4468|M.smegmatis_MC2_155 VAAAYRESFDAFSAEHPGIEVRVNTVAYA-SYFDSLRTDVAGGSADDIFW
MAB_1715c|M.abscessus_ATCC_199 VAEAYRGSFDEFSRRNPDIQVAVTVTSYA-SYFNSLRTDVAGHGADDIFW
TH_2011|M.thermoresistible__bu QMSDAQRLAPHFEAANPDIRLKFVTLSENQARAKITASTAMGGGEFDVVM
* :*.*.: : . : . * . *:.
Mb2345|M.bovis_AF2122/97 LSNAYFAAYADSGRLMKIQT--------DAADWEPAVVDQFTRSGVLWGV
Rv2318|M.tuberculosis_H37Rv LSNAYFAAYADSGRLMKIQT--------DAADWEPAVVDQFTRSGVLWGV
MMAR_3619|M.marinum_M LSNAYLAAYADSGRLMKIDTAV------DPGEWEPAVVDQFTRNGVLWGV
MUL_1246|M.ulcerans_Agy99 LSNAYLAAYADSGRLMKIDTAV------DPGEWEPAVVDQFTRNGVLWGV
MLBr_01770|M.leprae_Br4923 LSSAYLAAYADNGRLINISNSLGQR---ATSDWEPAVVDQFTRAGALWGV
MAV_2088|M.avium_104 LSNAYLAAYADSGRLLNILDTLGTN---AAADWERPVVEQFTRHGQLWGV
MSMEG_4468|M.smegmatis_MC2_155 ISNGYFAGYADNGHLLDIADLLGPD---AATAWEPSVVEQFTRNGALWGV
MAB_1715c|M.abscessus_ATCC_199 LSNAYLSDYADTGNLVPVEP---------RADWDPSVVAQFTRDGKLWGV
TH_2011|M.thermoresistible__bu ISNYETPQWAADGWLVNLSDYARQTPGYDEDDFIPSIRESLSYEGDMYAV
:*. . :* * *: : : .: .:: * ::.*
Mb2345|M.bovis_AF2122/97 PQLTDAGIAVFYNADLLAAAGVDPTQVDNLRWSRGDD-DTLRPMLARLTV
Rv2318|M.tuberculosis_H37Rv PQLTDAGIAVFYNADLLAAAGVDPTQVDNLRWSRGDD-DTLRPMLARLTV
MMAR_3619|M.marinum_M PQLTDAGIAVFYNADLLAAAGVDPAELDGLRWSPGPD-DTLRALLARLTV
MUL_1246|M.ulcerans_Agy99 PQLTDAGIAVFYNADLLAAAGVDPAELDGLRWSPGPD-DTLRALLARLTV
MLBr_01770|M.leprae_Br4923 PQLTDAGIAVFYNADLLTAAGIDPVQLNRMQWTSNDD-DTLRPLLTQLTL
MAV_2088|M.avium_104 PQLTDAGIALYYNADLLGAAGIDPAQLNSLRWNPAGG-DTLRPLLARLTV
MSMEG_4468|M.smegmatis_MC2_155 PQLTDAGIAVYYNADLLEKAGVSPADLSTLRWSNGPD-DTLRPLLARLTV
MAB_1715c|M.abscessus_ATCC_199 PQLSDAGIALYYNKNLLDAAQVDPAELAELRWDPDPEVDTLRPMLHRLTA
TH_2011|M.thermoresistible__bu PFYGES-SFLMYRKDLFEKSGIDMPHNPTWQQVADAAAALDTPDMAGICL
* :: : *. :*: : :. . : . : :
Mb2345|M.bovis_AF2122/97 DADGRTANTPGFDARRVRQWGYNAANDPQAIYLNYIGSAGGVFQRDGKFA
Rv2318|M.tuberculosis_H37Rv DADGRTANTPGFDARRVRQWGYNAANDPQAIYLNYIGSAGGVFQRDGKFA
MMAR_3619|M.marinum_M DADGHVGGTPGFDPGRVRQWGYNAANDPQAIYLNYIGSAGGVFMRDNEFA
MUL_1246|M.ulcerans_Agy99 DADGHVGGTPGFDPGRVRQWGYNAANDPQAIYLNYIGSAGGVFMRDNEFA
MLBr_01770|M.leprae_Br4923 DTNGHVAKTPGFDSRRVRQWGYNAANDPQAIYLNYIGSAGGVFQRGDEFA
MAV_2088|M.avium_104 DADGNRGDTRGFDPGRVRQWGYNAANDPQGIYLNYIGSAGGVFQRGDEFA
MSMEG_4468|M.smegmatis_MC2_155 EESG-----------RTRQWGYNAANDLQGIYLNFIGSAGGTFSEGDRFT
MAB_1715c|M.abscessus_ATCC_199 ----------------PGHWGYNAANDLQGIYLNYLGSAGAVFQADDKFA
TH_2011|M.thermoresistible__bu R----------------GKPGWGEVLAPLDTVINTFG--GRWYDMDWNAQ
: *:. . :* :* * : . .
Mb2345|M.bovis_AF2122/97 FDNPGAIEAFRYLVGLINDDHVAPPASDTNDNGDFSRNQFLAGKMALFQS
Rv2318|M.tuberculosis_H37Rv FDNPGAIEAFRYLVGLINDDHVAPPASDTNDNGDFSRNQFLAGKMALFQS
MMAR_3619|M.marinum_M FDNPPAIDAFRYLVGLINNDHVAPPASDTNDNGDFSRNQFLAGRMALFQS
MUL_1246|M.ulcerans_Agy99 FDNPPAIDAFRYLVGLINNDHVAPPASDTNDNGDFSRNQFLAGRMALFQS
MLBr_01770|M.leprae_Br4923 FDNPSAVEAFRYLVGLINNDHVAPPASETNNNGDFSRNQFLSGRMALFQS
MAV_2088|M.avium_104 FDNPAAVSAFRYLVDLINRDHVAPPAADTNDNGDFSRNQFLAGRMALFQS
MSMEG_4468|M.smegmatis_MC2_155 FDNPQAVEAFEYLVRLINTDRVAPPASDTNDNGDFSRNAFLAGRMALFQS
MAB_1715c|M.abscessus_ATCC_199 FAKPRAEMAFTYLVDLINVDRVAPSAADTNDNNDFSRNQFLQGRMALFQS
TH_2011|M.thermoresistible__bu LDSPEVEEAVSFYVNLVRDHGEPGPATSGFG---ECATQFAQGRAAMWYD
: .* . *. : * *:. . . .*:. . . . * *: *:: .
Mb2345|M.bovis_AF2122/97 GTYSLAPVAR----DALFHWGVAMLPAGPAGRVSVTNGIAAAGNSASKHP
Rv2318|M.tuberculosis_H37Rv GTYSLAPVAR----DALFHWGVAMLPAGPAGRVSVTNGIAAAGNSASKHP
MMAR_3619|M.marinum_M GTYSLAPVAR----DATFRWGVAMLPIGPAGRVSVTNGIAAAGNSASQHP
MUL_1246|M.ulcerans_Agy99 GTYSLAPVAR----DATFRWGVAMLPIGPAGRVSVTNGIAAAGNSASQHP
MLBr_01770|M.leprae_Br4923 GTYNLALIAR----EARFHWGIAMMPTGPQGRVSVTNGIAVAGNSATKHP
MAV_2088|M.avium_104 GTYNLAPVAR----DARFRWGVAMMPAGPVGRVSVTNGIAAAGNAATKHP
MSMEG_4468|M.smegmatis_MC2_155 GTYNLAAIAD----QAPFPWGVAMLPIGPKGRVSVTNGIAAAGNAATRHP
MAB_1715c|M.abscessus_ATCC_199 GTYNLAQIQA----NATFPWDVAMMPAGPQGRVSVTNGIVAAANSSSPHP
TH_2011|M.thermoresistible__bu ATSAVSVLEDPAQSNVVGKVGYALAPTVVKADAGWLYTWALGIPASSDNK
.* :: : :. . *: * . .. . . ::: :
Mb2345|M.bovis_AF2122/97 DAVRQVLAWMGSTEGNSYVGRHG---AAIPAVLSAQPVYFDYWSARGVDV
Rv2318|M.tuberculosis_H37Rv DAVRQVLAWMGSTEGNSYLGRHG---AAIPAVLSAQPVYFDYWSARGVDV
MMAR_3619|M.marinum_M DAVRQVLAWMGSSAGNEYLGRDG---VAIPAVRSAQPSYFAFWEAKGVNV
MUL_1246|M.ulcerans_Agy99 DAVRQVLAWMGSSAGNEYLGRDG---VAIPAVRSAQPSYFAFWEAKGVNV
MLBr_01770|M.leprae_Br4923 DAVRQVLAWMGSREGNAYLGRHG---AAVPAVRSAQSVYFDYWAAKGIDV
MAV_2088|M.avium_104 GAVRQVLAWMGSRQGNEYLGRYG---AAIPAVTSAQPVYFGYWAARGVDV
MSMEG_4468|M.smegmatis_MC2_155 EAVREVLAWMGSRRGNEFVGRRG---AAIPAVLAAQPVYHEYWASRGVDV
MAB_1715c|M.abscessus_ATCC_199 DAVHKVLAWMGSTDGNSFLGRSG---SAIPAVLSARAPYFQYWADKGVDV
TH_2011|M.thermoresistible__bu DSAWKFISWMTDKNYIRLVGEELGWARVPPGNRLSTYQIPEYQQASEAFG
:. :.::** . :*. . *. : :
Mb2345|M.bovis_AF2122/97 TPFFAVLNGPRIAAPGGA-------------GFAAGQQALEPYFDEMFLG
Rv2318|M.tuberculosis_H37Rv TPFFAVLNGPRIAAPGGA-------------GFAAGQQALEPYFDEMFLG
MMAR_3619|M.marinum_M EPFFAVLSGSRIPAPGGA-------------GFAAGNDALKPYFDEMFLG
MUL_1246|M.ulcerans_Agy99 NPFFAVLSGSRIPAPGGA-------------GFAAGNDALKPYFDEMFLG
MLBr_01770|M.leprae_Br4923 TPFFSVLDGPHIPAPGGA-------------GFPAGDDALQSYFDEMFLG
MAV_2088|M.avium_104 TPFFAVLNGPRIAAPGGA-------------GFAAGNDALRPYFDEMFSG
MSMEG_4468|M.smegmatis_MC2_155 SPFFRVLQGPRIAAPGGA-------------GFPAGFEALTPYFAEMFLG
MAB_1715c|M.abscessus_ATCC_199 SPFFEVLRGQQIAAPGGQ-------------GFGAGFAALKPYFAEMFLG
TH_2011|M.thermoresistible__bu QVTLESLENADTQHPTVQPVPYTGVQFLAIPEFQDLGTRVSQQISAAIAG
: * . * * : : : *
Mb2345|M.bovis_AF2122/97 RGDVTTTLRQAQAAANAATQR-----
Rv2318|M.tuberculosis_H37Rv RGDVTTTLRQAQAAANAATQR-----
MMAR_3619|M.marinum_M RGQVATILREAQAAANAAARR-----
MUL_1246|M.ulcerans_Agy99 RGQVATILREAQAAANAAARR-----
MLBr_01770|M.leprae_Br4923 HGDVEKILCQAQAAANTAAHR-----
MAV_2088|M.avium_104 RGDVATTLRRAQAAANAAAARR----
MSMEG_4468|M.smegmatis_MC2_155 RRDVAGTLAEAQRAANAAASR-----
MAB_1715c|M.abscessus_ATCC_199 RLDVREALQQAQRAANRALER-----
TH_2011|M.thermoresistible__bu QKSVKDALAQAQKYAQVVGKTYQEKP
: .* * .** *: .