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M. smegmatis MC2 155 MSMEG_5145 (-)

annotation: extracellular solute-binding protein, family protein 1
coordinates: 5251100 - 5252485
length: 461

VDLKSVDANVVESKADFLPSTSRRAFLAAALSVPLLGALAACGSSGPSRSGGGGGGAPGAASYWFLSSQP
QESIRTAAVERFNQANPDQQIQYTAFQNDAYKTKIKTAVGAGQAPTIIFGWGGGTLRSYVDAGQVDDLTS
WFDENPAVKDRLFPTAFGPATIDGRIYAMPAEVVQPVVLYYNKEVFDKVGAAPPQSWGDIMDLVPKFNAT
GVAPISLAGQSRWPEMMWLEFLFDRLGGPEVFEAAYEGEHNAWSHPAAIDALTKVQELIKADGFVRGFSS
VTPDSNADQALLYTGKAAMMLQGSWTYGGMATDGGDFVSSGKLGYMNFPPVDGGTGDPSTTVGNPAQYLS
IYSKATDEQKEVAKKFLSTAVLSDQEIKEWIDIGSVPIVQGTQGQLAGSDDADFLEFIYRVSTEAKTFGQ
SWDQALSPTAAETLLDNIAKLFQLSISPQQFADNMNQATSR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5145--100% (461)extracellular solute-binding protein, family protein 1
M. smegmatis MC2 155MSMEG_0515-1e-1421.68% (392) sugar transporter sugar binding lipoprotein
M. smegmatis MC2 155MSMEG_0505-9e-1121.35% (459) sugar ABC transporter, substrate-binding protein, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2067c-1e-0722.92% (301) sugar-binding lipoprotein
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv2041c-5e-0823.26% (301) sugar-binding lipoprotein
M. leprae Br4923MLBr_01427-8e-0824.30% (321) putative ABC-transport lipoprotein
M. abscessus ATCC 19977MAB_1715c-1e-0621.89% (233) sugar ABC transporter, sugar-binding protein
M. marinum MMMAR_3014-2e-0523.11% (264) sugar-binding lipoprotein
M. avium 104MAV_2476-7e-0922.82% (298) sugar ABC transporter, sugar-binding protein
M. thermoresistible (build 8)TH_2011-4e-0925.00% (224) substrate binding protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_01427|M.leprae_Br4923          ---------------MHGKLFGRRSLLRGAGALTAAALAPGAVGCS----
MMAR_3014|M.marinum_M               ---------------MFDKPLRRRELLRGAGLLTAAALAPVAAGCA----
Mb2067c|M.bovis_AF2122/97           ---------------MVNKPFERRSLLRGAGALTAASLAPWAAGCA----
Rv2041c|M.tuberculosis_H37Rv        ---------------MVNKPFERRSLLRGAGALTAASLAPWAAGCA----
MAV_2476|M.avium_104                ---------------MLDRPFGRRSLLRGAGALSAAALAPWSAGCG----
MAB_1715c|M.abscessus_ATCC_199      -----------------MKASTRAALTLALVALLLFGVAAWLGIPT----
TH_2011|M.thermoresistible__bu      -----------------VRRTPIRAVLAAVAAVCLTLTGCAGAGTL----
MSMEG_5145|M.smegmatis_MC2_155      MDLKSVDANVVESKADFLPSTSRRAFLAAALSVPLLGALAACGSSGPSRS
                                                             .  .   :                 

MLBr_01427|M.leprae_Br4923          ----SDDD-ALTFFFAANPEETNARMRIVGEFQRDHPDIKVRAVLSG--P
MMAR_3014|M.marinum_M               ----SDDD-ALTFFFAANPEEADARIRVVDAFGRSHPDIKVRTLLSG--P
Mb2067c|M.bovis_AF2122/97           ----ADDDDALTFFFAANPDELRPRMRVVNEFQRRYPDIKVRALLSG--P
Rv2041c|M.tuberculosis_H37Rv        ----ADDDDALTFFFAANPDELRPRMRVVNEFQRRYPDIKVRALLSG--P
MAV_2476|M.avium_104                ----SDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLSG--P
MAB_1715c|M.abscessus_ATCC_199      ----TPHGKTVVTVRVWDQQVAEAYRGSFDEFSRRNPDIQVAVTVTSY-A
TH_2011|M.thermoresistible__bu      ----GSSGNTVTIALVSNSQMSDAQR-LAPHFEAANPDIRLKFVTLSENQ
MSMEG_5145|M.smegmatis_MC2_155      GGGGGGAPGAASYWFLSSQPQESIRTAAVERFNQANPDQQIQYTAFQN-D
                                             :       .             *    ** ::         

MLBr_01427|M.leprae_Br4923          GVMQQLSTFCAGGKCPDVLMAWD-LTYAELADRGVLLDLNTLLGQDKAFA
MMAR_3014|M.marinum_M               GALQQISTFCAGGKCPDVLMAWE-LSYAELADRGVFLDLNTMLARDQKFA
Mb2067c|M.bovis_AF2122/97           GVMQQLATFCAGGKCPDVLMAWE-LTYAELADRGVLLDLNTLLARDQVFA
Rv2041c|M.tuberculosis_H37Rv        GVMQQLATFCAGGKCPDVLMAWE-LTYAELADRGVLLDLNTLLARDQAFA
MAV_2476|M.avium_104                GVMQQLSTFCVGGRCPDVLMAWE-LSYAELADRGVLLDLGPLLARDKAFA
MAB_1715c|M.abscessus_ATCC_199      SYFNSLRTDVAGHGADDIFWLSN-AYLSDYADTGNLVPVEPRADWDPSVV
TH_2011|M.thermoresistible__bu      ARAKITASTAMGGGEFDVVMISN-YETPQWAADGWLVNLSDYARQTPGYD
MSMEG_5145|M.smegmatis_MC2_155      AYKTKIKTAVGAGQAPTIIFGWGGGTLRSYVDAGQVDDLTSWFDENPAVK
                                    .      :   .     :.         . .  * .  :           

MLBr_01427|M.leprae_Br4923          AELKSDSIEPLYETFTFNGGQYAFPEQWSGNYLFYN-KQLFTNAGVQPPP
MMAR_3014|M.marinum_M               DELAADSIGALYDTFAYNGGQYAFPEQWSGNFLFYN-RGLFADGGVPPPP
Mb2067c|M.bovis_AF2122/97           AELKSDSIGALYETFTFNGGQYAFPEQWSGNFLFYN-KQLFDDAGVPPPP
Rv2041c|M.tuberculosis_H37Rv        AELKSDSIGALYETFTFNGGQYAFPEQWSGNFLFYN-KQLFDDAGVPPPP
MAV_2476|M.avium_104                QQLQADSIPALYETFTFNGKQYALPEQWSGNYLFYN-KRLFDEAGVPSPP
MAB_1715c|M.abscessus_ATCC_199      AQFTRD------------GKLWGVPQLSDAGIALYY-NKNLLDAAQVDPA
TH_2011|M.thermoresistible__bu      ED---DFIPSIRESLSYEGDMYAVPFYGESSFLMYR-KDLFEKSGIDMPH
MSMEG_5145|M.smegmatis_MC2_155      DRLFPTAFG----PATIDGRIYAMPAEVVQPVVLYYNKEVFDKVGAAPPQ
                                                      *  :..*        :*  .  : . .   * 

MLBr_01427|M.leprae_Br4923          -CTWEQPWSFTEFLDTARALTKRDSSGRVTQWGFVNTWLSYYTAGLFALN
MMAR_3014|M.marinum_M               -TSWDQPWSFAEFLDTARALTKRDGAGRVTQWGFVDTFVPPLSAGLFALN
Mb2067c|M.bovis_AF2122/97           -GSWERPWSFAEFLDAAQALTKQGRSGRDRQWGFVNAWVSFYAAGLFAMN
Rv2041c|M.tuberculosis_H37Rv        -GSWERPWSFAEFLDAAQALTKQGRSGRDRQWGFVNAWVSFYAAGLFAMN
MAV_2476|M.avium_104                -TAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTWGSYYSAGLFAMN
MAB_1715c|M.abscessus_ATCC_199      -ELAELRWDPDPEVDTLRPMLHRLTAPG--HWGYN---AANDLQGIYLNY
TH_2011|M.thermoresistible__bu      NPTWQQVADAAAALDTPDMAG--ICLRGKPGWGEVLAPLDTVINTFGGRW
MSMEG_5145|M.smegmatis_MC2_155      --SWGDIMDLVPKFNATGVAP--ISLAGQSRWPEM-----MWLEFLFDRL
                                            .    .::               :             :    

MLBr_01427|M.leprae_Br4923          NGVPWSNPRMNPTHLNFDDDAFIEAVQFYCDLTNKYQVAPDASEQQWMA-
MMAR_3014|M.marinum_M               NGVPWSTPRMNPTHLNFDDDAFIEAVQFYADLSAKHQVAPTASELQSIA-
Mb2067c|M.bovis_AF2122/97           NGVPWSVPRMNPTHLNFDHDGFLEAVQFYADLTNKHKVAPSAAEQQSMS-
Rv2041c|M.tuberculosis_H37Rv        NGVPWSVPRMNPTHLNFDHDGFLEAVQFYADLTNKHKVAPSAAEQQSMS-
MAV_2476|M.avium_104                NGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQSMS-
MAB_1715c|M.abscessus_ATCC_199      LGSAGAVFQAD-DKFAFAKPRAEMAFTYLVDLINVDRVAPSAADTNDNND
TH_2011|M.thermoresistible__bu      YDMDWN--------AQLDSPEVEEAVSFYVNLVRDHGEPGPATSGFGEC-
MSMEG_5145|M.smegmatis_MC2_155      GGPEVFEAAYEGEHNAWSHPAAIDALTKVQELIKADGFVRGFSSVTPDSN
                                     .                      *.    :*          :.      

MLBr_01427|M.leprae_Br4923          -TADLFSLGKAAIALGGHWRYQTFMR-AEGLDFD--VTSLPIGPSAGTVP
MMAR_3014|M.marinum_M               -TTDLFSLGKAAMALGGHWRYQTFDR-ADGLEFD--VTALPLGPNG----
Mb2067c|M.bovis_AF2122/97           -TADLFSVGKAGIALAGHWRYQTFDR-ADGLDFD--VAPLPIGPRG----
Rv2041c|M.tuberculosis_H37Rv        -TADLFSVGKAGIALAGHWRYQTFDR-ADGLDFD--VAPLPIGPRG----
MAV_2476|M.avium_104                -TPNLFAVGRAAMALGGHWRYQTYLR-AEGLDFD--VAPLPVGPAVGK--
MAB_1715c|M.abscessus_ATCC_199      FSRNQFLQGRMALFQSGTYNLAQIQA-NATFPWD--VAMMPAGPQG----
TH_2011|M.thermoresistible__bu      --ATQFAQGRAAMWYDATSAVSVLEDPAQSNVVG--KVGYALAPTVVK--
MSMEG_5145|M.smegmatis_MC2_155      ADQALLYTGKAAMMLQGSWTYGGMATDGGDFVSSGKLGYMNFPPVDGGTG
                                         :  *: .:   .                .         *      

MLBr_01427|M.leprae_Br4923          ATRSGACSDIGATGLAIAASSSRKEQAWEFVKFATGPAGQALIGESC---
MMAR_3014|M.marinum_M               ---RAACSNIGATGLAIAASSARKEQAWEFVKFATGPAGQALIGETD---
Mb2067c|M.bovis_AF2122/97           ---RAACSDIGVTGLAIAATSRRKDQAWEFVKFATGPVGQALIGESR---
Rv2041c|M.tuberculosis_H37Rv        ---RAACSDIGVTGLAIAATSRRKDQAWEFVKFATGPVGQALIGESR---
MAV_2476|M.avium_104                --GQPACSDIGATGLAISSSSPRKEQAWEFVKFATGPVGQALIGESC---
MAB_1715c|M.abscessus_ATCC_199      -----RVSVTNGIVAAANSSSPHPDAVHKVLAWMGSTDGNSFLGRSG---
TH_2011|M.thermoresistible__bu      ----ADAGWLYTWALGIPASSDNKDSAWKFISWMTDKNYIRLVGEELGWA
MSMEG_5145|M.smegmatis_MC2_155      DPSTTVGNPAQYLSIYSKATDEQKEVAKKFLSTAVLSDQEIKEWIDIG--
                                           .          ::. . : . :.:                   

MLBr_01427|M.leprae_Br4923          ----------LFVPVLQSAIYST---GFAKAHNRVANLAVLTGGPVHSAG
MMAR_3014|M.marinum_M               ----------LFVPVLGSALNSA---GFAKAHRRVDNLAVLTAGPGHSQG
Mb2067c|M.bovis_AF2122/97           ----------LFVPVLRSAINSH---GFANAHRRVGNLAVLSEGPAYSEG
Rv2041c|M.tuberculosis_H37Rv        ----------LFVPVLRSAINSH---GFANAHRRVGNLAVLSEGPAYSEG
MAV_2476|M.avium_104                ----------LFVPVLRSALKSD---GFARAHRRVGNLGVLTDGPAFSQG
MAB_1715c|M.abscessus_ATCC_199      ----------SAIPAVLSARAPY---FQYWADKGVDVSPFFEVLRGQQIA
TH_2011|M.thermoresistible__bu      RVPPGNRLSTYQIPEYQQASEAFGQVTLESLENADTQHPTVQPVPYTGVQ
MSMEG_5145|M.smegmatis_MC2_155      -----------SVPIVQGTQGQLA--GSDDADFLEFIYRVSTEAKTFGQS
                                                :*    :            .                  

MLBr_01427|M.leprae_Br4923          LPITPAWEKINALMDRNFGPVLRG-VRPATSLAGLARAVDEVLNSP----
MMAR_3014|M.marinum_M               LPITPAWPKVHALMDRNFGPVLRG-SRPATSLIGMSRALDEVLRSP----
Mb2067c|M.bovis_AF2122/97           LPVTPAWEKIAALMDRYFGPVLRG-SRPATSLTGLSQAVDEVLRNP----
Rv2041c|M.tuberculosis_H37Rv        LPVTPAWEKIAALMDRYFGPVLRG-SRPATSLTGLSQAVDEVLRNP----
MAV_2476|M.avium_104                LPITPAWEKVNALMDRNFGPILRG-SRPATSLAGLSRSVDEVLRSP----
MAB_1715c|M.abscessus_ATCC_199      APGGQGFGAGFAALKPYFAEMFLGRLDVREALQQAQRAANRALER-----
TH_2011|M.thermoresistible__bu      FLAIPEFQDLGTRVSQQISAAIAGQKSVKDALAQAQKYAQVVGKTYQEKP
MSMEG_5145|M.smegmatis_MC2_155      WDQALSPTAAETLLDN-IAKLFQLSISPQQFADNMNQATSR---------
                                               : :.  :.  :              :  .