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LTVDFDRLGVGPGTSVIDVGCGAGRHTFEAFRRGAHVIGFDQNVADLNSVDEMLQAMAEAGEAPATAKGE AVKGDALDLPYEDGTFDCVIASEILEHVPEDDRAISELVRVLKPGGSLAITVPRWLPEKICWLLSDEYHA NEGGHIRIYKADELRDKVLAHGLELTHTHHEHALHSPYWWLKCLVGTEKNDHPAVKAYHQLLVWDMMGRP WLTRTAESALNPLIGKSVALYFTKPDARG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_6483 | - | - | 100% (240) | methyltransferase type 11 |
M. smegmatis MC2 155 | MSMEG_0098 | - | 4e-14 | 34.90% (149) | methyltransferase |
M. smegmatis MC2 155 | MSMEG_2329 | - | 1e-10 | 31.48% (108) | methyltransferase, UbiE/COQ5 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1440c | - | 6e-11 | 34.51% (113) | putative methyltransferase |
M. gilvum PYR-GCK | Mflv_1100 | - | 1e-124 | 87.29% (236) | methyltransferase type 11 |
M. tuberculosis H37Rv | Rv1405c | - | 6e-11 | 34.51% (113) | putative methyltransferase |
M. leprae Br4923 | MLBr_00551 | - | 3e-11 | 35.40% (113) | putative methyltransferase |
M. abscessus ATCC 19977 | MAB_3381c | - | 3e-10 | 31.48% (108) | hypothetical protein MAB_3381c |
M. marinum M | MMAR_2924 | - | 1e-103 | 70.17% (238) | SAM-dependent methyltransferase |
M. avium 104 | MAV_2756 | - | 1e-102 | 70.21% (235) | methyltransferase |
M. thermoresistible (build 8) | TH_0087 | - | 1e-114 | 77.08% (240) | methyltransferase type 11 |
M. ulcerans Agy99 | MUL_1900 | - | 3e-10 | 30.56% (108) | hypothetical protein MUL_1900 |
M. vanbaalenii PYR-1 | Mvan_5717 | - | 1e-125 | 87.39% (238) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1440c|M.bovis_AF2122/97 ----------MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPI Rv1405c|M.tuberculosis_H37Rv ----------MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPI MLBr_00551|M.leprae_Br4923 ----------MNLYTPIHEDQSLAAIHRAMWALGDYALMAEEVMAPLGPI Mflv_1100|M.gilvum_PYR-GCK ----------------------------------------------MLTV Mvan_5717|M.vanbaalenii_PYR-1 ----------------------------------------------MLTV MSMEG_6483|M.smegmatis_MC2_155 ----------------------------------------------MLTV TH_0087|M.thermoresistible__bu ----------------------------------------------MLTV MMAR_2924|M.marinum_M ----------------------------------------------MLTV MAV_2756|M.avium_104 ----------------------------------------------MLTV MAB_3381c|M.abscessus_ATCC_199 MTEITGL--DGQPTTKATAEQVAAAFEDNKLAQILYHDWEAETYDEKWSI MUL_1900|M.ulcerans_Agy99 MTRSSEIPADAAPNPHATAEEVEAARHDSKLAQVLYHDWEAENYDEKWSI .: Mb1440c|M.bovis_AF2122/97 LVAAAGIG------------------PGVRVLDVAAGSGNISLPAAKTGA Rv1405c|M.tuberculosis_H37Rv LVAAAGIG------------------PGVRVLDVAAGSGNISLPAAKTGA MLBr_00551|M.leprae_Br4923 LVTATGIR------------------PGMQVLDVAAGSGNISLPAAKTGA Mflv_1100|M.gilvum_PYR-GCK DFDRLGVG------------------AGTKVIDVGCGAGRHTFEAFRRGA Mvan_5717|M.vanbaalenii_PYR-1 DFDRLGVG------------------AGTKVIDVGCGAGRHTFEAFRRGA MSMEG_6483|M.smegmatis_MC2_155 DFDRLGVG------------------PGTSVIDVGCGAGRHTFEAFRRGA TH_0087|M.thermoresistible__bu DYDRLGIG------------------PGVSVIDVGCGLGRHSFEAYRRGA MMAR_2924|M.marinum_M DFDRLGIG------------------PGATVIDVGCGAGRHAFEAYRCGA MAV_2756|M.avium_104 DFDRLGIG------------------PSSKVIDVGCGAGRHAFEAYRRGA MAB_3381c|M.abscessus_ATCC_199 SYDQRCIDYARGRFDAIVPVEDQRELPYDRALELGCGTGFFLLNLMQAGV MUL_1900|M.ulcerans_Agy99 SYDQRCVEYARGRFDAIVPAQVHADLPYERALELGCGTGFFLLNLIQAGV : . .:::..* * : : *. Mb1440c|M.bovis_AF2122/97 TVISTD--------LTPELLQRSQARAAQQGLTLQYQEANAQALPFADDE Rv1405c|M.tuberculosis_H37Rv TVISTD--------LTPELLQRSQARAAQQGLTLQYQEANAQALPFADDE MLBr_00551|M.leprae_Br4923 TIVSTD--------LTPELLQRSQARATELGLTLEYREADAQALPFGDGE Mflv_1100|M.gilvum_PYR-GCK DVIGFDQSASDLNDVDEILQAMKEQGEAPASAKGEAVKGDALELPYADGT Mvan_5717|M.vanbaalenii_PYR-1 DVVGFDQSVSDLNDVDEILQAMKEQGEVPASAKGEAVKGDALDLPYADGT MSMEG_6483|M.smegmatis_MC2_155 HVIGFDQNVADLNSVDEMLQAMAEAGEAPATAKGEAVKGDALDLPYEDGT TH_0087|M.thermoresistible__bu HIVAFDQNAEELNEVDTILQAMAEQREAPAGARAEVVKGDALDLPYADGT MMAR_2924|M.marinum_M DVVAFDRDAAELRAVDTMLRAMAQTGEAPAAASAKVVLGDALALPYPDGT MAV_2756|M.avium_104 DVVAFDQNEAELRSVDTVLRAMADSGEAPAGASATVVVGDALKLPYPDQT MAB_3381c|M.abscessus_ATCC_199 ARRGSVT------DLSPGMVKVATRTGQELGLDVDGRVADAERIPYDDNT MUL_1900|M.ulcerans_Agy99 ARRGSVT------DLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYDDDT . : : .:* :*: * Mb1440c|M.bovis_AF2122/97 FDTVISAIGVMFAPDHQAAADELVRVCRPGG--TIGVISWTCEGFFGRML Rv1405c|M.tuberculosis_H37Rv FDTVISAIGVMFAPDHQAAADELVRVCRPGG--TIGVISWTCEGFFGRML MLBr_00551|M.leprae_Br4923 FDVVMSAIGVMFAPDHRRAASELVRVCRPNG--TIGVISWTQEGFFGRML Mflv_1100|M.gilvum_PYR-GCK FDCVIASEILEHVPADDKAISELVRVLKPGGALAITVPRWLPERIC---W Mvan_5717|M.vanbaalenii_PYR-1 FDCVIASEILEHVPEDDRAIAELVRVLKPGGALAITVPRWLPERIC---W MSMEG_6483|M.smegmatis_MC2_155 FDCVIASEILEHVPEDDRAISELVRVLKPGGSLAITVPRWLPEKIC---W TH_0087|M.thermoresistible__bu FDRVIASEILEHVPEDDRAIAELVRVLKPGGKLVVTVPRWLPERIC---W MMAR_2924|M.marinum_M FDCVIASEILEHVPQDDAAIAELVRVLKVGGTLAISVPRWLPERVC---W MAV_2756|M.avium_104 FDCVIASEILEHIPHDDAAIAELIRVLKVGGTLAVSVPRWLPERVC---W MAB_3381c|M.abscessus_ATCC_199 FDLVVGHAVLHHIPDVELSLREVLRVLKPGGRFVFAGEPTTVGNLYARAL MUL_1900|M.ulcerans_Agy99 FDLVVGHAVLHHIPDVELSLREVMRVLKPGGRFVFAGEPTTVGNEYARTL ** *:. : . * : *::** : .* .. Mb1440c|M.bovis_AF2122/97 ATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVKRFD Rv1405c|M.tuberculosis_H37Rv ATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVKRFD MLBr_00551|M.leprae_Br4923 ATIRPYRPSLSAALPPAALWGREAYIRGLLDDTVTNVKTERRQLEVKRFN Mflv_1100|M.gilvum_PYR-GCK ALSDEYHANEGGHIR---IYRADELRDKVLAHGLTLTHTHHSHALHSPFW Mvan_5717|M.vanbaalenii_PYR-1 ALSDEYHANEGGHIR---IYRADELRDKVLAHGLALTHIHHAHALHSPYW MSMEG_6483|M.smegmatis_MC2_155 LLSDEYHANEGGHIR---IYKADELRDKVLAHGLELTHTHHEHALHSPYW TH_0087|M.thermoresistible__bu LLSDEYHANEGGHVR---IYRADELRDKITRHGLRLTHRHHAHALHSPFW MMAR_2924|M.marinum_M LLSDEYHSNEGGHVR---VYRASELREKITRHPMALTHAHHAHALHSPFW MAV_2756|M.avium_104 LLSDEYHSNEGGHVR---IYRASDLRAKILSGGMTLTHAHHAHALHSPFW MAB_3381c|M.abscessus_ATCC_199 ADLTWKATVQAMKLPGLESWRRPQEELDENSRAAALEWVVDLHTFDPADL MUL_1900|M.ulcerans_Agy99 STLTWRIATNVTKLPGLGGWRRPQEELDESSRAAALEAIVDLHTFAPEDL . : : Mb1440c|M.bovis_AF2122/97 TAQAVHD---YFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSD Rv1405c|M.tuberculosis_H37Rv TAQAVHD---YFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSD MLBr_00551|M.leprae_Br4923 SAEGVHN---YFKNHYGPTIEAYTNIGDNSVLAAELDAQLTELAQKYLTN Mflv_1100|M.gilvum_PYR-GCK WLKCAVG---TEKNDH-PAVAAYHKLLVWDMMSQPWLTRTAEAALNPLIG Mvan_5717|M.vanbaalenii_PYR-1 WLKCAVG---TEKTNH-PAVAAYHKLLVWDMMGRPWLTRTAEAALNPLIG MSMEG_6483|M.smegmatis_MC2_155 WLKCLVG---TEKNDH-PAVKAYHQLLVWDMMGRPWLTRTAESALNPLIG TH_0087|M.thermoresistible__bu WLKCAVG---TNNDRH-FAVRAYHQLLVWDMVRRPWVTRWAEEMLNPLIG MMAR_2924|M.marinum_M WLKCAVG---VSNADH-PLVSAYHKLLVWDLMRRPRVTRMAESVLNPLVG MAV_2756|M.avium_104 WLKCAVG---VHNTDH-RAVAAYHKLLVWDLMRRPKITQLAESLLNPLVG MAB_3381c|M.abscessus_ATCC_199 EKMAANAGAVAVRTASEEFTAAMLGWPVRTFESTVPPGKLGWGWAKFAFN MUL_1900|M.ulcerans_Agy99 ERMAKNAGAIRVETASEEFSAAMFGWPVRTFESSVPPGRLGWNWARFAFN . * . : . . Mb1440c|M.bovis_AF2122/97 GVMEWEYLLLTAEKR------------------ Rv1405c|M.tuberculosis_H37Rv GVMEWEYLLLTAEKR------------------ MLBr_00551|M.leprae_Br4923 STMGWEYLLLTAQKH------------------ Mflv_1100|M.gilvum_PYR-GCK KSVALYFRKPADTDA------------------ Mvan_5717|M.vanbaalenii_PYR-1 KSVALYFRKPAAADA------------------ MSMEG_6483|M.smegmatis_MC2_155 KSVALYFTKPDARG------------------- TH_0087|M.thermoresistible__bu KSVALYFDKPEVAGADS---------------- MMAR_2924|M.marinum_M KSVAMYFDKRESAQSPADLGHSVASA------- MAV_2756|M.avium_104 KSVAMYFVKRQDAKSQATAGYSIASV------- MAB_3381c|M.abscessus_ATCC_199 GWKALSWVDENVWRHVVPKGWYYNVMITGIKPS MUL_1900|M.ulcerans_Agy99 GWKALGWMDANVWRHVAPKGWFYNVMVTGVKPS :