For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSRASLEKNPHDVASMFDAVAKRYDLTNTVLSLGQDRFWRRETKSALRIGPADKVLDLAAGTAVSTVELA KSGAWCVAADFSVGMLAAGASRQVPKVAGDATRLPFADEVFDAVTISFGLRNVVDHKAGLREMARVTKPG GRLVVCEFSTPTNRLFSTVYKEYLMKALPAMATAVSSNPEAYVYLAESIRAWPTQAELARQIGEAGWSDV RWRNLTGGIVALHAATKPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1115 | ubiE | - | 100% (229) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. smegmatis MC2 155 | MSMEG_0098 | - | 2e-12 | 41.51% (106) | methyltransferase |
M. smegmatis MC2 155 | MSMEG_2285 | - | 1e-11 | 32.87% (143) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0573 | ubiE | 1e-106 | 82.02% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. gilvum PYR-GCK | Mflv_5258 | ubiE | 1e-114 | 89.04% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. tuberculosis H37Rv | Rv0558 | ubiE | 1e-106 | 82.02% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. leprae Br4923 | MLBr_02273 | ubiE | 3e-99 | 75.88% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. abscessus ATCC 19977 | MAB_3930c | - | 1e-103 | 80.09% (226) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
M. marinum M | MMAR_0907 | ubiE | 1e-107 | 84.21% (228) | ubiquinone/menaquinone methlytransferase, MenH |
M. avium 104 | MAV_4584 | ubiE | 1e-107 | 83.77% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. thermoresistible (build 8) | TH_0087 | - | 8e-10 | 36.28% (113) | methyltransferase type 11 |
M. ulcerans Agy99 | MUL_0660 | ubiE | 1e-107 | 83.77% (228) | ubiquinone/menaquinone biosynthesis methyltransferase |
M. vanbaalenii PYR-1 | Mvan_0983 | ubiE | 1e-113 | 87.67% (227) | ubiquinone/menaquinone biosynthesis methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0573|M.bovis_AF2122/97 -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL Rv0558|M.tuberculosis_H37Rv -----------------MSRAALDKDPRDVASMFDGVARKYDLTNTVLSL MMAR_0907|M.marinum_M -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL MUL_0660|M.ulcerans_Agy99 -----------------MSRAALDKDPRDVASMFDGVARRYDLTNTVLSL MAV_4584|M.avium_104 MQRWRRRGIPAPGSVKRVSRAELDKNPRDVASMFDGVARRYDLTNTVLSL MLBr_02273|M.leprae_Br4923 ---------MPPGSVDVVSRAALDKDPRDVVAMFDDVAHRYDLTNTVLSL Mflv_5258|M.gilvum_PYR-GCK -----------------MNRASLEKNPHEVASMFDGVARRYDLTNTVLSL Mvan_0983|M.vanbaalenii_PYR-1 -----------------MNRASLEKDPHEVASMFDGVARRYDLTNTVLSL MSMEG_1115|M.smegmatis_MC2_155 -----------------MSRASLEKNPHDVASMFDAVAKRYDLTNTVLSL MAB_3930c|M.abscessus_ATCC_199 -----------------MNRATLEKDPHEVASMFDAVARRYDITNTVLSF TH_0087|M.thermoresistible__bu ----------------------------MLTVDYDRLGIGPGVSVIDVGC :. :* :. .:: :. Mb0573|M.bovis_AF2122/97 GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELTKSGAWCVAADFSV Rv0558|M.tuberculosis_H37Rv GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTVELTKSGAWCVAADFSV MMAR_0907|M.marinum_M GQDRYWRRATRSALRIGPGDKVLDLAAGTAVSTVELAKSGAWCVAADFSV MUL_0660|M.ulcerans_Agy99 GQDRYWRRATRSALRIGPGDKVLDLAAGTAVSSVELAKSGAWCVAADFSV MAV_4584|M.avium_104 GQDRYWRKATRSALGIGPGQKVLDLAAGTAVSTVELNKSGAWCVAADFSV MLBr_02273|M.leprae_Br4923 GQDRYWRRATRSALRIGPGQKVLDLAAGTAVSTAELSKSGAWCVAADFSV Mflv_5258|M.gilvum_PYR-GCK GQDRFWRRATREALQLSPADKVLDLAAGTAVSTVELASSGAWCVAADFSV Mvan_0983|M.vanbaalenii_PYR-1 GQDRFWRRATREALQLSPSDKVLDLAAGTAVSTVELAGSGAWCVAADFSV MSMEG_1115|M.smegmatis_MC2_155 GQDRFWRRETKSALRIGPADKVLDLAAGTAVSTVELAKSGAWCVAADFSV MAB_3930c|M.abscessus_ATCC_199 GRDRFWRRATREALRLKPGDKVLDIAAGTAVSTAELTQSGAWCVAADFSV TH_0087|M.thermoresistible__bu GLGRHSFEAYRRGAHIVAFDQNAEELNEVDTILQAMAEQ----------- * .*. . : . : . :: : . . : . Mb0573|M.bovis_AF2122/97 GMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREM Rv0558|M.tuberculosis_H37Rv GMLAAGAARKVPKVAGDATRLPFGDDVFDAVTISFGLRNVANQQAALREM MMAR_0907|M.marinum_M GMLAAGHERKVCKVAGDATRLPFADDVFDAVTISFGLRNVVDFSAALREM MUL_0660|M.ulcerans_Agy99 GMLAAGHERRVCKVAGDATRLPFADDVFDAVTISFGLRNVVDFSAALREM MAV_4584|M.avium_104 GMLAAGAARRVPKVAGDATRLPFADDVFDAVTISFGLRNVVDTQAALREM MLBr_02273|M.leprae_Br4923 RMLATGGARKVPKVAADATQLPFSDGVFDAVTISFGLRNIADYQAALREM Mflv_5258|M.gilvum_PYR-GCK GMLAAGASRRVPKVAGDATRLPFDDGVFDAVTISFGLRNVVDFSAGLREM Mvan_0983|M.vanbaalenii_PYR-1 GMLAAGAARDVPKVAGDATRLPFADGVFDAVTISFGLRNVVDHSAGLREM MSMEG_1115|M.smegmatis_MC2_155 GMLAAGASRQVPKVAGDATRLPFADEVFDAVTISFGLRNVVDHKAGLREM MAB_3930c|M.abscessus_ATCC_199 GMLKAGARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREM TH_0087|M.thermoresistible__bu --REAPAGARAEVVKGDALDLPYADGTFDRVIASEILEHVPEDDRAIAEL : . * .** **: * ** * * *.:: : .: *: Mb0573|M.bovis_AF2122/97 ARVTRPGGRLLVCEFSTPTNALFATAYKEYLMR--------ALPRVARAV Rv0558|M.tuberculosis_H37Rv ARVTRPGGRLLVCEFSTPTNALFATAYKEYLMR--------ALPRVARAV MMAR_0907|M.marinum_M ARVTRPGGRLVVCEFSTPVSALFATVYKEYLMR--------ALPRVARAV MUL_0660|M.ulcerans_Agy99 ARVTRPGGRLVVCEFSTPVSALFATVYKEYLMR--------ALPRVARAV MAV_4584|M.avium_104 ARVTRPGGRLVVCEFSTPSNALFATVYKEYLMR--------ALPRVARAV MLBr_02273|M.leprae_Br4923 ARVTRPGGQLVVCEFSTPTNALVANVYTEYLMR--------ALPQVARLV Mflv_5258|M.gilvum_PYR-GCK ARVTRPGGRLVVCEFSTPTNGLFSTVYKEYLMK--------ALPAMATAV Mvan_0983|M.vanbaalenii_PYR-1 ARVTRPGGRLVVCEFSTPTNKLFATVYKEYLMR--------ALPAMASAV MSMEG_1115|M.smegmatis_MC2_155 ARVTKPGGRLVVCEFSTPTNRLFSTVYKEYLMK--------ALPAMATAV MAB_3930c|M.abscessus_ATCC_199 ARVTKPGGRLAVCEFSTPVNRPFRTLYMEYLMK--------TLPEVARAV TH_0087|M.thermoresistible__bu VRVLKPGGKLVVTVPRWLPERICWLLSDEYHANEGGHVRIYRADELRDKI .** :***:* * . ** . : : Mb0573|M.bovis_AF2122/97 SSN-------------PEAYEYLAESIRAWPD--------QAVLAHQISR Rv0558|M.tuberculosis_H37Rv SSN-------------PEAYEYLAESIRAWPD--------QAVLAHQISR MMAR_0907|M.marinum_M SSN-------------PEAYVYLAESIRAWPD--------QAALAQQMSR MUL_0660|M.ulcerans_Agy99 SSN-------------PEAYVYLAESIRAWPD--------QAALAQQMSR MAV_4584|M.avium_104 SSN-------------PDAYVYLAESIRAWPD--------QAALADQIAG MLBr_02273|M.leprae_Br4923 SSN-------------PDAYIYLAESIRAWPD--------QVTLACQLSR Mflv_5258|M.gilvum_PYR-GCK SSN-------------PDAYVYLAESIRAWPD--------QRALARRIEA Mvan_0983|M.vanbaalenii_PYR-1 SSN-------------PDAYVYLAESIRAWPD--------QAELAARIEA MSMEG_1115|M.smegmatis_MC2_155 SSN-------------PEAYVYLAESIRAWPT--------QAELARQIGE MAB_3930c|M.abscessus_ATCC_199 SSN-------------PDAYVYLAESIRAWPD--------QEALAHQIAS TH_0087|M.thermoresistible__bu TRHGLRLTHRHHAHALHSPFWWLKCAVGTNNDRHFAVRAYHQLLVWDMVR : : ..: :* :: : : *. : Mb0573|M.bovis_AF2122/97 ----AGWSGVRWRNLTGGIVALHAGYKPGKQTPQ Rv0558|M.tuberculosis_H37Rv ----AGWSGVRWRNLTGGIVALHAGYKPGKQTPQ MMAR_0907|M.marinum_M ----AGWSAVRWRNLTGGIVALHAGYKP---QPV MUL_0660|M.ulcerans_Agy99 ----AGWSAVRWRNLTGGIVALHAGYKP---QPV MAV_4584|M.avium_104 ----AGWAGVRWRNLTGGIVALHAAHRP----PR MLBr_02273|M.leprae_Br4923 ----TGWASPRWRNLTGGIVALHAADKP----VR Mflv_5258|M.gilvum_PYR-GCK ----AGWSDVRWRNLTGGIVALHAATKP------ Mvan_0983|M.vanbaalenii_PYR-1 ----AGWSDVRWRNLTGGIVALHAATKA------ MSMEG_1115|M.smegmatis_MC2_155 ----AGWSDVRWRNLTGGIVALHAATKPA----- MAB_3930c|M.abscessus_ATCC_199 ----AGWSNVRWRNLTGGIVALHIATL------- TH_0087|M.thermoresistible__bu RPWVTRWAEEMLNPLIGKSVALYFDKPEVAGADS : *: . * * ***: